MET_knockout_263_GSE8747 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE8747
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Genes

600 genes differentially expressed following the MET_knockout_263_GSE8747 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
PEX6 peroxisomal biogenesis factor 6 2.87988
L3MBTL2 l(3)mbt-like 2 (Drosophila) 2.61031
MMP2 matrix metallopeptidase 2 2.49431
ARMT1 acidic residue methyltransferase 1 2.4762
RFESD Rieske (Fe-S) domain containing 2.43027
ERCC2 excision repair cross-complementation group 2 2.42189
PMM2 phosphomannomutase 2 2.42152
C10ORF128 chromosome 10 open reading frame 128 2.31654
SIAE sialic acid acetylesterase 2.28822
RFX1 regulatory factor X, 1 (influences HLA class II expression) 2.2739
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 2.26097
SLAIN1 SLAIN motif family, member 1 2.20217
GNA12 guanine nucleotide binding protein (G protein) alpha 12 2.18072
LMCD1 LIM and cysteine-rich domains 1 2.16225
KIF2B kinesin family member 2B 2.15761
LAMA5 laminin, alpha 5 2.15492
HOXD3 homeobox D3 2.15201
TOM1 target of myb1 (chicken) 2.15039
SH3BP5L SH3-binding domain protein 5-like 2.14841
PVRL4 poliovirus receptor-related 4 2.13723
SLC22A18 solute carrier family 22, member 18 2.11533
C15ORF52 chromosome 15 open reading frame 52 2.11211
IRG1 immunoresponsive 1 homolog (mouse) 2.10812
SSNA1 Sjogren syndrome nuclear autoantigen 1 2.08972
PICK1 protein interacting with PRKCA 1 2.08455
NXPH4 neurexophilin 4 2.08106
SORBS1 sorbin and SH3 domain containing 1 2.08089
ANKRD52 ankyrin repeat domain 52 2.08087
SBNO2 strawberry notch homolog 2 (Drosophila) 2.05467
FOXRED1 FAD-dependent oxidoreductase domain containing 1 2.02655
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.00907
MKRN1 makorin ring finger protein 1 1.99373
ATG7 autophagy related 7 1.99036
KY kyphoscoliosis peptidase 1.96997
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 1.93922
NUB1 negative regulator of ubiquitin-like proteins 1 1.91446
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.91327
GSS glutathione synthetase 1.90131
USF2 upstream transcription factor 2, c-fos interacting 1.89284
TSGA10 testis specific, 10 1.87378
TEX261 testis expressed 261 1.82212
SCN11A sodium channel, voltage gated, type XI alpha subunit 1.81684
C4ORF19 chromosome 4 open reading frame 19 1.79613
EHD3 EH-domain containing 3 1.78752
IL27 interleukin 27 1.78459
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.77356
CDX1 caudal type homeobox 1 1.75595
PEX16 peroxisomal biogenesis factor 16 1.754
TPRKB TP53RK binding protein 1.75293
GTF2IRD1 GTF2I repeat domain containing 1 1.75292
MPPE1 metallophosphoesterase 1 1.75041
RFC2 replication factor C (activator 1) 2, 40kDa 1.74465
GJB2 gap junction protein, beta 2, 26kDa 1.73939
PCSK6 proprotein convertase subtilisin/kexin type 6 1.7382
GAB2 GRB2-associated binding protein 2 1.73478
ARNT aryl hydrocarbon receptor nuclear translocator 1.71132
PLEKHA7 pleckstrin homology domain containing, family A member 7 1.70611
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 1.70526
MYH10 myosin, heavy chain 10, non-muscle 1.70416
IGFALS insulin-like growth factor binding protein, acid labile subunit 1.69193
SMYD2 SET and MYND domain containing 2 1.69172
DCBLD1 discoidin, CUB and LCCL domain containing 1 1.68816
ZFP36L2 ZFP36 ring finger protein-like 2 1.683
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative) 1.68255
SNF8 SNF8, ESCRT-II complex subunit 1.65813
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 1.6491
EVPL envoplakin 1.64789
RBM10 RNA binding motif protein 10 1.64458
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.6362
SFXN3 sideroflexin 3 1.63432
IL15RA interleukin 15 receptor, alpha 1.62929
RAB24 RAB24, member RAS oncogene family 1.62822
C18ORF25 chromosome 18 open reading frame 25 1.62818
SH2B1 SH2B adaptor protein 1 1.62043
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 1.61682
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.61418
TMED1 transmembrane emp24 protein transport domain containing 1 1.61117
SMTN smoothelin 1.60142
RNASEH2A ribonuclease H2, subunit A 1.5922
ELOVL1 ELOVL fatty acid elongase 1 1.58352
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 1.57838
UNC13A unc-13 homolog A (C. elegans) 1.57536
ANAPC1 anaphase promoting complex subunit 1 1.57201
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 1.57171
OPCML opioid binding protein/cell adhesion molecule-like 1.56934
C16ORF74 chromosome 16 open reading frame 74 1.56881
RAE1 ribonucleic acid export 1 1.56369
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 1.56283
TRABD TraB domain containing 1.56205
NSUN5 NOP2/Sun domain family, member 5 1.55885
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 1.55719
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 1.55636
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.55003
TFIP11 tuftelin interacting protein 11 1.54755
CCDC25 coiled-coil domain containing 25 1.54069
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 1.53988
TGM1 transglutaminase 1 1.53579
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.53403
CREB3L3 cAMP responsive element binding protein 3-like 3 1.52608
RCOR2 REST corepressor 2 1.51382
IGFBP3 insulin-like growth factor binding protein 3 1.50937
ZNF717 zinc finger protein 717 1.50331
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.50234
PPP1R9A protein phosphatase 1, regulatory subunit 9A 1.50193
CAMSAP1 calmodulin regulated spectrin-associated protein 1 1.48601
FADS6 fatty acid desaturase 6 1.48353
RNF216 ring finger protein 216 1.48262
FGF4 fibroblast growth factor 4 1.48244
ADRA2A adrenoceptor alpha 2A 1.47839
MRPS10 mitochondrial ribosomal protein S10 1.47536
PXN paxillin 1.46723
CAND1 cullin-associated and neddylation-dissociated 1 1.46686
PISD phosphatidylserine decarboxylase 1.46222
PWWP2B PWWP domain containing 2B 1.45812
APEH acylaminoacyl-peptide hydrolase 1.45552
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.45514
SEC31A SEC31 homolog A (S. cerevisiae) 1.44866
C16ORF92 chromosome 16 open reading frame 92 1.44667
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 1.44511
CDC20 cell division cycle 20 1.44265
PEX5 peroxisomal biogenesis factor 5 1.44193
CDK10 cyclin-dependent kinase 10 1.4417
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.44045
CENPJ centromere protein J 1.44032
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.44014
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 1.43499
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 1.43369
KIF1C kinesin family member 1C 1.43074
NNAT neuronatin 1.42572
RAB1B RAB1B, member RAS oncogene family 1.42526
PDCD5 programmed cell death 5 1.42416
FGF1 fibroblast growth factor 1 (acidic) 1.42393
RAB30 RAB30, member RAS oncogene family 1.42332
RAB9B RAB9B, member RAS oncogene family 1.42076
CUEDC2 CUE domain containing 2 1.42065
EHD1 EH-domain containing 1 1.41775
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.41728
AATK apoptosis-associated tyrosine kinase 1.41156
ANXA11 annexin A11 1.41103
MED30 mediator complex subunit 30 1.40898
ZNF169 zinc finger protein 169 1.40742
COMMD5 COMM domain containing 5 1.40232
BSDC1 BSD domain containing 1 1.39883
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 1.39754
GAS8 growth arrest-specific 8 1.39174
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.39078
PPL periplakin 1.39005
CAV3 caveolin 3 1.38951
FN3K fructosamine 3 kinase 1.38746
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 1.38569
PDE4A phosphodiesterase 4A, cAMP-specific 1.37974
RNF19B ring finger protein 19B 1.37968
WDR4 WD repeat domain 4 1.37755
CCDC59 coiled-coil domain containing 59 1.37436
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.37036
OMP olfactory marker protein 1.36783
KRT78 keratin 78, type II 1.36666
BRI3BP BRI3 binding protein 1.36623
DGKQ diacylglycerol kinase, theta 110kDa 1.36612
NWD1 NACHT and WD repeat domain containing 1 1.36288
CBR1 carbonyl reductase 1 1.3611
ABHD4 abhydrolase domain containing 4 1.36065
FBXL14 F-box and leucine-rich repeat protein 14 1.35975
TTC7A tetratricopeptide repeat domain 7A 1.35555
RXRB retinoid X receptor, beta 1.35496
PGLS 6-phosphogluconolactonase 1.35479
SCML4 sex comb on midleg-like 4 (Drosophila) 1.35224
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.35199
BBS4 Bardet-Biedl syndrome 4 1.35198
FSCN1 fascin actin-bundling protein 1 1.34876
C11ORF86 chromosome 11 open reading frame 86 1.34348
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 1.34332
PADI1 peptidyl arginine deiminase, type I 1.34061
TBKBP1 TBK1 binding protein 1 1.34007
PPP4C protein phosphatase 4, catalytic subunit 1.33457
MRPL4 mitochondrial ribosomal protein L4 1.33405
WDR5 WD repeat domain 5 1.33154
MTX1 metaxin 1 1.32807
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 1.32803
SPATS1 spermatogenesis associated, serine-rich 1 1.32403
LDHD lactate dehydrogenase D 1.3203
CCDC70 coiled-coil domain containing 70 1.31946
MRPL46 mitochondrial ribosomal protein L46 1.31283
GPR146 G protein-coupled receptor 146 1.31189
ZNHIT2 zinc finger, HIT-type containing 2 1.30913
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.30698
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.30326
MFAP3 microfibrillar-associated protein 3 1.30154
PSAP prosaposin 1.30001
SIT1 signaling threshold regulating transmembrane adaptor 1 1.29969
ZFYVE9 zinc finger, FYVE domain containing 9 1.29344
MYEF2 myelin expression factor 2 1.29331
PFKL phosphofructokinase, liver 1.2907
POLR2H polymerase (RNA) II (DNA directed) polypeptide H 1.29027
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 1.29027
RAB26 RAB26, member RAS oncogene family 1.28987
TRIM17 tripartite motif containing 17 1.28823
TSPO translocator protein (18kDa) 1.28611
ZDHHC5 zinc finger, DHHC-type containing 5 1.28271
ZFP64 ZFP64 zinc finger protein 1.28211
NANP N-acetylneuraminic acid phosphatase 1.28166
PXMP4 peroxisomal membrane protein 4, 24kDa 1.28124
MRPS34 mitochondrial ribosomal protein S34 1.28015
AXIN1 axin 1 1.27967
FGF19 fibroblast growth factor 19 1.27446
PTPN14 protein tyrosine phosphatase, non-receptor type 14 1.27237
ALK anaplastic lymphoma receptor tyrosine kinase 1.26997
OR13F1 olfactory receptor, family 13, subfamily F, member 1 1.26862
STK32A serine/threonine kinase 32A 1.26608
POU3F2 POU class 3 homeobox 2 1.26476
TMC7 transmembrane channel-like 7 1.26006
TAPBPL TAP binding protein-like 1.25537
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.25464
KCTD13 potassium channel tetramerization domain containing 13 1.25343
KIAA0195 KIAA0195 1.25164
NPHP1 nephronophthisis 1 (juvenile) 1.25087
MED16 mediator complex subunit 16 1.24858
HSPA12B heat shock 70kD protein 12B 1.24626
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 1.24465
EGR2 early growth response 2 1.24249
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 1.23988
FNTB farnesyltransferase, CAAX box, beta 1.23921
YEATS4 YEATS domain containing 4 1.23907
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.23877
MMP11 matrix metallopeptidase 11 1.23818
RBPMS2 RNA binding protein with multiple splicing 2 1.23558
TUFM Tu translation elongation factor, mitochondrial 1.23551
CCR7 chemokine (C-C motif) receptor 7 1.23455
HDAC6 histone deacetylase 6 1.22835
GALNS galactosamine (N-acetyl)-6-sulfatase 1.2281
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.22444
BCL2L1 BCL2-like 1 1.22251
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 1.2218
PBX2 pre-B-cell leukemia homeobox 2 1.22128
ZNF236 zinc finger protein 236 1.22049
GLIS3 GLIS family zinc finger 3 1.2203
SND1 staphylococcal nuclease and tudor domain containing 1 1.21936
TNRC6B trinucleotide repeat containing 6B 1.21557
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 1.21474
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.21464
PCTP phosphatidylcholine transfer protein 1.21366
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 1.21085
MAP3K10 mitogen-activated protein kinase kinase kinase 10 1.20984
STEAP1 six transmembrane epithelial antigen of the prostate 1 1.20756
NUBPL nucleotide binding protein-like 1.20755
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 1.2068
MST1 macrophage stimulating 1 1.20663
HNRNPL heterogeneous nuclear ribonucleoprotein L 1.20585
GPR22 G protein-coupled receptor 22 1.20519
KLHL22 kelch-like family member 22 1.20448
C11ORF24 chromosome 11 open reading frame 24 1.20227
SCHIP1 schwannomin interacting protein 1 1.20137
TACC1 transforming, acidic coiled-coil containing protein 1 1.20127
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 1.20087
PLP1 proteolipid protein 1 1.20083
CST9L cystatin 9-like 1.2008
DHRS7C dehydrogenase/reductase (SDR family) member 7C 1.19718
FADS2 fatty acid desaturase 2 1.19556
PDGFA platelet-derived growth factor alpha polypeptide 1.19421
KLHDC3 kelch domain containing 3 1.19028
MAP2K5 mitogen-activated protein kinase kinase 5 1.18919
MAGEB5 melanoma antigen family B5 1.18521
MAP3K14 mitogen-activated protein kinase kinase kinase 14 1.18436
ATCAY ataxia, cerebellar, Cayman type 1.18348
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.18251
ZNF324 zinc finger protein 324 1.18107
ATHL1 ATH1, acid trehalase-like 1 (yeast) 1.18009
DHRS7 dehydrogenase/reductase (SDR family) member 7 1.1798
KLHDC4 kelch domain containing 4 1.17827
IARS isoleucyl-tRNA synthetase 1.17761
OR52K2 olfactory receptor, family 52, subfamily K, member 2 1.17627
WDR55 WD repeat domain 55 1.1762
AUP1 ancient ubiquitous protein 1 1.17484
IRF3 interferon regulatory factor 3 1.17382
METTL2A methyltransferase like 2A 1.1737
EPB41L5 erythrocyte membrane protein band 4.1 like 5 1.1731
ALOX12B arachidonate 12-lipoxygenase, 12R type 1.17287
C14ORF37 chromosome 14 open reading frame 37 1.17235
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.17226
ALDH16A1 aldehyde dehydrogenase 16 family, member A1 1.17206
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.17067
CD37 CD37 molecule 1.17012
PPAP2B phosphatidic acid phosphatase type 2B 1.1696
EI24 etoposide induced 2.4 1.1692
STIM1 stromal interaction molecule 1 1.16719
MPV17 MpV17 mitochondrial inner membrane protein 1.16568
OCLN occludin 1.16561
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.16491
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.16395
C11ORF68 chromosome 11 open reading frame 68 1.1621
JMJD4 jumonji domain containing 4 1.15945
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 1.15661
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 1.15582
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 1.15521
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 1.15406
H1FX H1 histone family, member X 1.15388
TCN2 transcobalamin II 1.15297
CCDC6 coiled-coil domain containing 6 1.15214
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.15126
HMGA1 high mobility group AT-hook 1 1.14848

decreased expression

Symbol Name Standardized Value
LMBRD2 LMBR1 domain containing 2 -4.00808
PON3 paraoxonase 3 -3.59611
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 -3.58201
MAP2K1 mitogen-activated protein kinase kinase 1 -3.57601
ADSS adenylosuccinate synthase -3.56705
SPIRE2 spire-type actin nucleation factor 2 -3.44411
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -3.4183
MIS12 MIS12 kinetochore complex component -3.34784
KNTC1 kinetochore associated 1 -3.26168
GOLIM4 golgi integral membrane protein 4 -3.21988
MYOT myotilin -3.21538
FMR1 fragile X mental retardation 1 -3.21272
TM9SF3 transmembrane 9 superfamily member 3 -3.14458
OR5I1 olfactory receptor, family 5, subfamily I, member 1 -3.09114
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -3.04235
KRT72 keratin 72, type II -3.0349
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -3.01919
USP9X ubiquitin specific peptidase 9, X-linked -3.00277
NBN nibrin -2.92509
WWTR1 WW domain containing transcription regulator 1 -2.87918
PRX periaxin -2.86616
ATAD1 ATPase family, AAA domain containing 1 -2.81906
ZNF473 zinc finger protein 473 -2.80753
CD164 CD164 molecule, sialomucin -2.80101
PARVB parvin, beta -2.79388
MTIF2 mitochondrial translational initiation factor 2 -2.79161
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.78403
IMPAD1 inositol monophosphatase domain containing 1 -2.77724
TMEM123 transmembrane protein 123 -2.77269
RBMS2 RNA binding motif, single stranded interacting protein 2 -2.76139
RSL1D1 ribosomal L1 domain containing 1 -2.75769
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -2.7162
LAPTM4A lysosomal protein transmembrane 4 alpha -2.70989
RNF111 ring finger protein 111 -2.68543
MEGF9 multiple EGF-like-domains 9 -2.67988
CLK1 CDC-like kinase 1 -2.65058
AP4B1 adaptor-related protein complex 4, beta 1 subunit -2.64969
GIMAP6 GTPase, IMAP family member 6 -2.64694
OR8B4 olfactory receptor, family 8, subfamily B, member 4 (gene/pseudogene) -2.6463
GEMIN6 gem (nuclear organelle) associated protein 6 -2.63881
C5ORF24 chromosome 5 open reading frame 24 -2.63526
CDH18 cadherin 18, type 2 -2.63343
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -2.62162
NACA nascent polypeptide-associated complex alpha subunit -2.60663
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.59509
MARK2 MAP/microtubule affinity-regulating kinase 2 -2.59138
EIF4A3 eukaryotic translation initiation factor 4A3 -2.56229
SCN4A sodium channel, voltage gated, type IV alpha subunit -2.55937
PECAM1 platelet/endothelial cell adhesion molecule 1 -2.55393
WDR59 WD repeat domain 59 -2.54614
GFM2 G elongation factor, mitochondrial 2 -2.53976
INTS6 integrator complex subunit 6 -2.53416
CNOT2 CCR4-NOT transcription complex, subunit 2 -2.52955
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -2.50628
MIER2 mesoderm induction early response 1, family member 2 -2.475
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -2.4531
TMEM41B transmembrane protein 41B -2.45155
OLFM3 olfactomedin 3 -2.43382
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -2.42287
MTUS1 microtubule associated tumor suppressor 1 -2.42072
LAS1L LAS1-like (S. cerevisiae) -2.40389
HAND1 heart and neural crest derivatives expressed 1 -2.39572
INTS8 integrator complex subunit 8 -2.39369
CBX3 chromobox homolog 3 -2.39312
TMEM45B transmembrane protein 45B -2.39282
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -2.39217
ARHGAP5 Rho GTPase activating protein 5 -2.3893
PARK2 parkin RBR E3 ubiquitin protein ligase -2.38549
TSC22D2 TSC22 domain family, member 2 -2.38484
SH3KBP1 SH3-domain kinase binding protein 1 -2.37896
GFRA4 GDNF family receptor alpha 4 -2.37124
NIPBL Nipped-B homolog (Drosophila) -2.36863
OR2A5 olfactory receptor, family 2, subfamily A, member 5 -2.35568
BMPR1A bone morphogenetic protein receptor, type IA -2.34749
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.34256
SOX4 SRY (sex determining region Y)-box 4 -2.33252
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -2.32661
METAP2 methionyl aminopeptidase 2 -2.31976
SERBP1 SERPINE1 mRNA binding protein 1 -2.3111
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -2.31079
CHMP5 charged multivesicular body protein 5 -2.30888
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -2.30581
CIITA class II, major histocompatibility complex, transactivator -2.30434
MAPKAP1 mitogen-activated protein kinase associated protein 1 -2.29277
DPP4 dipeptidyl-peptidase 4 -2.29257
NUP88 nucleoporin 88kDa -2.27365
SCOC short coiled-coil protein -2.27197
CPEB2 cytoplasmic polyadenylation element binding protein 2 -2.26224
SESN1 sestrin 1 -2.25107
COLEC12 collectin sub-family member 12 -2.24518
OIT3 oncoprotein induced transcript 3 -2.23239
F13B coagulation factor XIII, B polypeptide -2.22591
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -2.22403
NMI N-myc (and STAT) interactor -2.22354
ZNF653 zinc finger protein 653 -2.21996
TNRC6A trinucleotide repeat containing 6A -2.21655
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -2.21538
CLOCK clock circadian regulator -2.21097
LARP4 La ribonucleoprotein domain family, member 4 -2.20748
KLF12 Kruppel-like factor 12 -2.20425
CNOT6 CCR4-NOT transcription complex, subunit 6 -2.18538
ARR3 arrestin 3, retinal (X-arrestin) -2.184
ZNF274 zinc finger protein 274 -2.18217
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -2.17147
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -2.16907
LSP1 lymphocyte-specific protein 1 -2.15431
RNF138 ring finger protein 138, E3 ubiquitin protein ligase -2.15183
CREBBP CREB binding protein -2.14081
TGFBR1 transforming growth factor, beta receptor 1 -2.13888
NT5C3A 5'-nucleotidase, cytosolic IIIA -2.13588
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.13506
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) -2.13278
PITRM1 pitrilysin metallopeptidase 1 -2.12386
MED6 mediator complex subunit 6 -2.1199
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -2.11373
RORA RAR-related orphan receptor A -2.11
MAPK1 mitogen-activated protein kinase 1 -2.10922
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 -2.10863
RAD21 RAD21 homolog (S. pombe) -2.10838
TOP1 topoisomerase (DNA) I -2.10806
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -2.10704
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -2.10514
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) -2.1042
PROP1 PROP paired-like homeobox 1 -2.10342
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.10153
SPAST spastin -2.10135
PTPN2 protein tyrosine phosphatase, non-receptor type 2 -2.09845
ATXN7 ataxin 7 -2.09824
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -2.09469
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) -2.09066
TESK2 testis-specific kinase 2 -2.08976
PPP6C protein phosphatase 6, catalytic subunit -2.08971
SPIN1 spindlin 1 -2.08031
STXBP3 syntaxin binding protein 3 -2.07316
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.06985
ADCK2 aarF domain containing kinase 2 -2.06934
SNRPN small nuclear ribonucleoprotein polypeptide N -2.0646
GTPBP1 GTP binding protein 1 -2.06397
ZNF618 zinc finger protein 618 -2.06203
ITM2B integral membrane protein 2B -2.06178
COL6A1 collagen, type VI, alpha 1 -2.05898
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -2.05065
RBM45 RNA binding motif protein 45 -2.04921
TPP2 tripeptidyl peptidase II -2.04648
FBXL4 F-box and leucine-rich repeat protein 4 -2.04439
MUT methylmalonyl CoA mutase -2.04116
HSPA14 heat shock 70kDa protein 14 -2.03615
MRPL35 mitochondrial ribosomal protein L35 -2.03224
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.03167
DYNLT3 dynein, light chain, Tctex-type 3 -2.02902
TATDN1 TatD DNase domain containing 1 -2.02843
PLCH2 phospholipase C, eta 2 -2.02748
C2ORF57 chromosome 2 open reading frame 57 -2.0271
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -2.02446
KLF11 Kruppel-like factor 11 -2.02217
ACSM3 acyl-CoA synthetase medium-chain family member 3 -2.01979
EXOC6 exocyst complex component 6 -2.01844
ATP11C ATPase, class VI, type 11C -2.01748
ZFP36L1 ZFP36 ring finger protein-like 1 -2.016
ASB12 ankyrin repeat and SOCS box containing 12 -2.01565
SEBOX SEBOX homeobox -2.01423
DSG1 desmoglein 1 -2.00779
STAB2 stabilin 2 -2.00542
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.003
ENG endoglin -2.00241
IL17F interleukin 17F -1.99986
BACE2 beta-site APP-cleaving enzyme 2 -1.99932
KLF4 Kruppel-like factor 4 (gut) -1.99891
RPL6 ribosomal protein L6 -1.99879
LATS1 large tumor suppressor kinase 1 -1.9966
SBDS Shwachman-Bodian-Diamond syndrome -1.98934
SGPP1 sphingosine-1-phosphate phosphatase 1 -1.98556
GHSR growth hormone secretagogue receptor -1.98144
TWISTNB TWIST neighbor -1.97852
ZNF704 zinc finger protein 704 -1.97663
ANXA5 annexin A5 -1.97593
NCL nucleolin -1.97473
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) -1.97259
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -1.97229
TMEM154 transmembrane protein 154 -1.96654
COMTD1 catechol-O-methyltransferase domain containing 1 -1.96272
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M -1.95673
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -1.95358
CCNH cyclin H -1.95354
FANCE Fanconi anemia, complementation group E -1.95243
FBXW2 F-box and WD repeat domain containing 2 -1.95081
ZC3H7A zinc finger CCCH-type containing 7A -1.94819
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) -1.94571
ZNF454 zinc finger protein 454 -1.94537
PTHLH parathyroid hormone-like hormone -1.943
ADRB1 adrenoceptor beta 1 -1.94052
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -1.93719
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 -1.93146
COX18 COX18 cytochrome c oxidase assembly factor -1.92921
PVRL3 poliovirus receptor-related 3 -1.92783
CA8 carbonic anhydrase VIII -1.92758
WAC WW domain containing adaptor with coiled-coil -1.92056
STAT4 signal transducer and activator of transcription 4 -1.91939
SNX13 sorting nexin 13 -1.91905
PNPLA8 patatin-like phospholipase domain containing 8 -1.91868
AHCYL1 adenosylhomocysteinase-like 1 -1.91742
BANP BTG3 associated nuclear protein -1.91615
GNPAT glyceronephosphate O-acyltransferase -1.91597
NKG7 natural killer cell granule protein 7 -1.91176
ACBD3 acyl-CoA binding domain containing 3 -1.9106
C8B complement component 8, beta polypeptide -1.91054
RBM6 RNA binding motif protein 6 -1.91016
OPA1 optic atrophy 1 (autosomal dominant) -1.90863
COPB1 coatomer protein complex, subunit beta 1 -1.90376
CGN cingulin -1.89167
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -1.88604
ZBTB40 zinc finger and BTB domain containing 40 -1.88314
ZSWIM3 zinc finger, SWIM-type containing 3 -1.88269
SMG7 SMG7 nonsense mediated mRNA decay factor -1.881
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -1.87445
OCIAD1 OCIA domain containing 1 -1.87441
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 -1.87364
ZC3H7B zinc finger CCCH-type containing 7B -1.87338
HTRA3 HtrA serine peptidase 3 -1.87139
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -1.87133
ZNF326 zinc finger protein 326 -1.87127
SIRT2 sirtuin 2 -1.86777
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 -1.86398
HIPK1 homeodomain interacting protein kinase 1 -1.85994
NFE2L2 nuclear factor, erythroid 2-like 2 -1.85648
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 -1.85563
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -1.85188
TMEM161A transmembrane protein 161A -1.84883
C12ORF4 chromosome 12 open reading frame 4 -1.84578
CUL1 cullin 1 -1.84516
SMC2 structural maintenance of chromosomes 2 -1.84444
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 -1.83545
ADIPOR2 adiponectin receptor 2 -1.83422
CSE1L CSE1 chromosome segregation 1-like (yeast) -1.83198
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -1.83191
DLAT dihydrolipoamide S-acetyltransferase -1.82723
DEK DEK proto-oncogene -1.82687
OR4D10 olfactory receptor, family 4, subfamily D, member 10 -1.82605
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -1.82231
HBS1L HBS1-like translational GTPase -1.82055
SEC11A SEC11 homolog A (S. cerevisiae) -1.8188
DAPL1 death associated protein-like 1 -1.81632
LRRC26 leucine rich repeat containing 26 -1.81559
RSU1 Ras suppressor protein 1 -1.81375
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -1.81351
NCK1 NCK adaptor protein 1 -1.81334
GJA3 gap junction protein, alpha 3, 46kDa -1.81148
GNPTG N-acetylglucosamine-1-phosphate transferase, gamma subunit -1.8111
PUM2 pumilio RNA-binding family member 2 -1.80936
TBCCD1 TBCC domain containing 1 -1.80726
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -1.80137
CORIN corin, serine peptidase -1.80106
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -1.79766
NXT2 nuclear transport factor 2-like export factor 2 -1.7968
CCT2 chaperonin containing TCP1, subunit 2 (beta) -1.79601
LZTR1 leucine-zipper-like transcription regulator 1 -1.79147
SUMO1 small ubiquitin-like modifier 1 -1.78748
BGN biglycan -1.78717
DEGS2 delta(4)-desaturase, sphingolipid 2 -1.78625
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -1.78624
GPBP1 GC-rich promoter binding protein 1 -1.7831
TMCO1 transmembrane and coiled-coil domains 1 -1.78277
HYAL3 hyaluronoglucosaminidase 3 -1.78098
HNF4A hepatocyte nuclear factor 4, alpha -1.78053
MEMO1 mediator of cell motility 1 -1.7783
GTF2I general transcription factor IIi -1.77294
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -1.77235
FAHD2B fumarylacetoacetate hydrolase domain containing 2B -1.77235
POGZ pogo transposable element with ZNF domain -1.76897
STRN3 striatin, calmodulin binding protein 3 -1.76833
WDR24 WD repeat domain 24 -1.76807
THAP11 THAP domain containing 11 -1.76602
VCAM1 vascular cell adhesion molecule 1 -1.75849
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -1.75363
SLK STE20-like kinase -1.75337
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -1.75213
CLIC4 chloride intracellular channel 4 -1.75191
TCEA1 transcription elongation factor A (SII), 1 -1.75061
TOR1AIP2 torsin A interacting protein 2 -1.74986
MRPS11 mitochondrial ribosomal protein S11 -1.74763
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -1.74749
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) -1.74563
PRMT3 protein arginine methyltransferase 3 -1.74167
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -1.74125
NR1H2 nuclear receptor subfamily 1, group H, member 2 -1.74097
RAP1GAP RAP1 GTPase activating protein -1.73736
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -1.73289
SNX5 sorting nexin 5 -1.72778
COMMD7 COMM domain containing 7 -1.72751
RAN RAN, member RAS oncogene family -1.72674
IGFBP7 insulin-like growth factor binding protein 7 -1.7241
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -1.72357
OTX1 orthodenticle homeobox 1 -1.722
TSPYL2 TSPY-like 2 -1.7197
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.71629
TM2D3 TM2 domain containing 3 -1.71605
PEBP1 phosphatidylethanolamine binding protein 1 -1.71423
NARS asparaginyl-tRNA synthetase -1.71125
RHEBL1 Ras homolog enriched in brain like 1 -1.70931
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -1.70895