MEX3C Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mex-3 RNA binding family member C|This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 51320)
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Genes

328 genes differentially expressed following the MEX3C gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ZNF804A zinc finger protein 804A 2.82116
GH2 growth hormone 2 2.82116
NLRP1 NLR family, pyrin domain containing 1 2.82116
ADGRE3 adhesion G protein-coupled receptor E3 2.82116
ARL5C ADP-ribosylation factor-like 5C 2.82116
CHRM1 cholinergic receptor, muscarinic 1 2.82116
GATA6 GATA binding protein 6 2.82116
MSC musculin 2.82116
GLOD5 glyoxalase domain containing 5 2.82116
SAMD11 sterile alpha motif domain containing 11 2.82116
IL21R interleukin 21 receptor 2.82116
SPDYC speedy/RINGO cell cycle regulator family member C 2.82116
TEX101 testis expressed 101 2.82116
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 2.82116
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 2.82116
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.82116
SP100 SP100 nuclear antigen 2.82116
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 2.82116
KLLN killin, p53-regulated DNA replication inhibitor 2.82116
LRRC8C-DT LRRC8C divergent transcript 2.82116
MEIKIN meiotic kinetochore factor 2.82116
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.82116
GPR149 G protein-coupled receptor 149 2.82116
MSMP microseminoprotein, prostate associated 2.82116
NECTIN4 nectin cell adhesion molecule 4 2.82116
IL12RB1 interleukin 12 receptor, beta 1 2.82116
SHOX2 short stature homeobox 2 2.82116
PRRT1B proline rich transmembrane protein 1B 2.82116
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 2.73962
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 2.72992
SLC22A10 solute carrier family 22, member 10 2.67507
TMEM176B transmembrane protein 176B 2.67507
FABP1 fatty acid binding protein 1, liver 2.67507
COL19A1 collagen, type XIX, alpha 1 2.67507
SPINK6 serine peptidase inhibitor, Kazal type 6 2.67507
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 2.67507
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 2.67507
ASB15 ankyrin repeat and SOCS box containing 15 2.67507
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2.67507
FGL1 fibrinogen-like 1 2.67507
INSM2 insulinoma-associated 2 2.67507
LRRC10B leucine rich repeat containing 10B 2.67507
LOC124909439 uncharacterized LOC124909439 2.67507
CELA1 chymotrypsin-like elastase family, member 1 2.67507
TRPC5OS TRPC5 opposite strand 2.67507
CD69 CD69 molecule 2.67507
CRX cone-rod homeobox 2.67507
ANKK1 ankyrin repeat and kinase domain containing 1 2.67507
ATOH1 atonal homolog 1 (Drosophila) 2.67507
SFTPB surfactant protein B 2.67507
PTGFR prostaglandin F receptor (FP) 2.67507
KRT20 keratin 20, type I 2.67507
AADACL4 arylacetamide deacetylase-like 4 2.67507
HBA1 hemoglobin, alpha 1 2.67507
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 2.67507
FOLR2 folate receptor 2 (fetal) 2.67507
RSPO3 R-spondin 3 2.67507
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.67507
SHCBP1L SHC SH2-domain binding protein 1-like 2.67507
TAS2R13 taste receptor, type 2, member 13 2.67507
ACKR5 atypical chemokine receptor 5 2.67507
AANAT aralkylamine N-acetyltransferase 2.67507
ELOVL3 ELOVL fatty acid elongase 3 2.67507
MLN motilin 2.67507
PROZ protein Z, vitamin K-dependent plasma glycoprotein 2.67507
FOXC2 forkhead box C2 2.67507
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.67507
GPR37L1 G protein-coupled receptor 37 like 1 2.67507
HNRNPCL3 heterogeneous nuclear ribonucleoprotein C-like 3 2.67507
ZAR1 zygote arrest 1 2.67507
ZNF726 zinc finger protein 726 2.67507
SPMIP11 sperm microtubule inner protein 11 2.67507
LITAFD LITAF domain containing 2.67507
SERTM2 serine rich and transmembrane domain containing 2 2.67507
GARIN5B golgi associated RAB2 interactor family member 5B 2.67507
DIPK2B divergent protein kinase domain 2B 2.67507
RTL9 retrotransposon Gag like 9 2.67507
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 2.67507
OTOS otospiralin 2.67507
SOAT2 sterol O-acyltransferase 2 2.67507
PRG4 proteoglycan 4 2.67507
ASIC3 acid sensing (proton gated) ion channel 3 2.67507
DTHD1 death domain containing 1 2.67507
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.67507
MEOX2 mesenchyme homeobox 2 2.67507
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 2.67507
NKX2-4 NK2 homeobox 4 2.67507
RLBP1 retinaldehyde binding protein 1 2.67507
ATP13A5 ATPase type 13A5 2.67507
RS1 retinoschisin 1 2.67507
TUBA3D tubulin, alpha 3d 2.67507
ZBTB16 zinc finger and BTB domain containing 16 2.67507
OPN5 opsin 5 2.67507
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.67507
SLAMF7 SLAM family member 7 2.67507
GZMM granzyme M (lymphocyte met-ase 1) 2.67507
TACSTD2 tumor-associated calcium signal transducer 2 2.67507
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.67507
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.67507
ITK IL2-inducible T-cell kinase 2.67507
CPED1 cadherin-like and PC-esterase domain containing 1 2.67507
PRDM13 PR domain containing 13 2.67507
ITGB7 integrin, beta 7 2.67507
POF1B premature ovarian failure, 1B 2.67507
CNPY1 canopy FGF signaling regulator 1 2.67507
APLNR apelin receptor 2.67507
ZNF132 zinc finger protein 132 2.67507
CRHBP corticotropin releasing hormone binding protein 2.67507
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.67507
LRCOL1 leucine rich colipase-like 1 2.67507
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 2.67507
PRND prion protein 2 (dublet) 2.67507
C2CD4A C2 calcium-dependent domain containing 4A 2.67507
PRSS55 protease, serine, 55 2.67507
ZNF385C zinc finger protein 385C 2.67507
ACKR3 atypical chemokine receptor 3 2.67507
DLX3 distal-less homeobox 3 2.67507
EPO erythropoietin 2.67507
LHX2 LIM homeobox 2 2.67507
HHATL hedgehog acyltransferase-like 2.67507
C2ORF66 chromosome 2 open reading frame 66 2.67507
MKRN3 makorin ring finger protein 3 2.67507
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.67507
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.67507
C8ORF89 chromosome 8 open reading frame 89 2.67507
DHH desert hedgehog 2.67507
MUCL1 mucin-like 1 2.67507
AQP11 aquaporin 11 2.67507
TRAK2 trafficking protein, kinesin binding 2 2.67507
PCDHGA4 protocadherin gamma subfamily A, 4 2.67507
ODF4 outer dense fiber of sperm tails 4 2.67507
CLEC4G C-type lectin domain family 4, member G 2.67507
CDH19 cadherin 19, type 2 2.67507
NPBWR1 neuropeptides B/W receptor 1 2.67507
CPA5 carboxypeptidase A5 2.67507
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 2.67507
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.67507
RNASE11 ribonuclease, RNase A family, 11 (non-active) 2.67507
LRRC74B leucine rich repeat containing 74B 2.67507
FXYD4 FXYD domain containing ion transport regulator 4 2.67507
IL37 interleukin 37 2.67507
C22ORF31 chromosome 22 open reading frame 31 2.67507
STOML3 stomatin (EPB72)-like 3 2.67507
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 2.67507
MMRN1 multimerin 1 2.67507
ZNF831 zinc finger protein 831 2.67507
NR2F2 nuclear receptor subfamily 2, group F, member 2 2.67507
IL23R interleukin 23 receptor 2.67507
GOLGA8N golgin A8 family, member N 2.67507
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.67507
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.67507
NMUR2 neuromedin U receptor 2 2.67507
HMX1 H6 family homeobox 1 2.67507
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 2.67507
RAD9B RAD9 homolog B (S. pombe) 2.67507
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.67507
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.67507
MMP10 matrix metallopeptidase 10 2.67507
HEPACAM hepatic and glial cell adhesion molecule 2.67507
MMEL1 membrane metallo-endopeptidase-like 1 2.67507
KIAA0825 KIAA0825 2.67507
ORM1 orosomucoid 1 2.67507
ZPLD1 zona pellucida-like domain containing 1 2.67507
CSDC2 cold shock domain containing C2, RNA binding 2.67507
LAMP3 lysosomal-associated membrane protein 3 2.67507
GREM1 gremlin 1, DAN family BMP antagonist 2.67507
APOL3 apolipoprotein L, 3 2.67507
OR14A16 olfactory receptor, family 14, subfamily A, member 16 2.67507
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.67507
TEX35 testis expressed 35 2.67507
WDR11 WD repeat domain 11 2.6323
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 2.58972
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 2.58972
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.58972
CCDC154 coiled-coil domain containing 154 2.58972
CSMD3 CUB and Sushi multiple domains 3 2.58972
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2.58782
TMEM145 transmembrane protein 145 2.58484
CLTCL1 clathrin, heavy chain-like 1 2.48671
NUDCD1 NudC domain containing 1 2.48279
FKBP6 FK506 binding protein 6, 36kDa 2.4438
LSM12 LSM12 homolog (S. cerevisiae) 2.43274
SNX30 sorting nexin family member 30 2.43274
FIMP1 fertilization-influencing membrane protein 1 2.3886
STARD9 StAR-related lipid transfer (START) domain containing 9 2.3886
COL17A1 collagen, type XVII, alpha 1 2.3886
ARHGAP15 Rho GTPase activating protein 15 2.3886
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.3886
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.3868
COMMD7 COMM domain containing 7 2.36712
CCNL2 cyclin L2 2.35549
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 2.34841
SLC46A3 solute carrier family 46, member 3 2.33767
SMKR1 small lysine-rich protein 1 2.33767
ZSCAN31 zinc finger and SCAN domain containing 31 2.33681
RNF216 ring finger protein 216 2.33142
PKDCC protein kinase domain containing, cytoplasmic 2.32416
SIVA1 SIVA1, apoptosis-inducing factor 2.30267
PLEKHO2 pleckstrin homology domain containing, family O member 2 2.28062
TSHZ3 teashirt zinc finger homeobox 3 2.266
PIERCE2 piercer of microtubule wall 2 2.25829
ZDHHC3 zinc finger, DHHC-type containing 3 2.25772
DCAKD dephospho-CoA kinase domain containing 2.25746
GATD3 glutamine amidotransferase class 1 domain containing 3 2.25389
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.2523
SIRAL1 SIR2 antiphage like 1 2.23455
PLCH1 phospholipase C, eta 1 2.1934
POGK pogo transposable element with KRAB domain 2.14587
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 2.1307
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 2.1125
MTX2 metaxin 2 2.10502
SNX5 sorting nexin 5 2.0814
BACE2 beta-site APP-cleaving enzyme 2 2.07312
NEFH neurofilament, heavy polypeptide 2.07312
PCDH9 protocadherin 9 2.07312
CCDC124 coiled-coil domain containing 124 2.06337
BABAM2 BRISC and BRCA1 A complex member 2 2.06157
HESX1 HESX homeobox 1 2.05562
RAI14 retinoic acid induced 14 2.04467
DHODH dihydroorotate dehydrogenase (quinone) 2.04389
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 2.0315
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 2.0315
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 2.0315
PIERCE1 piercer of microtubule wall 1 2.03099
TSPAN2 tetraspanin 2 2.03099
AHCTF1 AT hook containing transcription factor 1 2.03099
TMEM126A transmembrane protein 126A 2.01935
NEMP1 nuclear envelope integral membrane protein 1 2.01611

decreased expression

Symbol Name Standardized Value
ZBED6 zinc finger, BED-type containing 6 -2.82116
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 -2.82116
SPARCL1 SPARC-like 1 (hevin) -2.82116
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) -2.82116
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 -2.82116
TDRD3 tudor domain containing 3 -2.75745
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -2.67507
KAZN kazrin, periplakin interacting protein -2.67507
AHCY adenosylhomocysteinase -2.67507
C5AR1 complement component 5a receptor 1 -2.67507
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -2.67507
TEX46 testis expressed 46 -2.67507
MBOAT4 membrane bound O-acyltransferase domain containing 4 -2.67507
RNF212B ring finger protein 212B -2.67507
TBC1D28 TBC1 domain family, member 28 -2.67507
GPR26 G protein-coupled receptor 26 -2.67507
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) -2.67507
FETUB fetuin B -2.67507
SACK1A scaffolding CK1 anchoring protein A -2.67507
THEM5 thioesterase superfamily member 5 -2.67507
PARP15 poly (ADP-ribose) polymerase family, member 15 -2.67507
IL6ST-DT IL6ST divergent transcript -2.67507
LIX1 Lix1 homolog (chicken) -2.67507
CNOT6 CCR4-NOT transcription complex, subunit 6 -2.67507
ZNF541 zinc finger protein 541 -2.67507
FAT1 FAT atypical cadherin 1 -2.67507
RUBCN rubicon autophagy regulator -2.67507
ZNF701 zinc finger protein 701 -2.67507
GPR150 G protein-coupled receptor 150 -2.67507
MEPE matrix extracellular phosphoglycoprotein -2.67507
LRRN4 leucine rich repeat neuronal 4 -2.67507
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 -2.67507
CLEC20A C-type lectin domain containing 20A -2.67507
ANGPTL8 angiopoietin like 8 -2.67507
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -2.67507
TMEM255A transmembrane protein 255A -2.67507
CDC20B cell division cycle 20B -2.67507
ULK4 unc-51 like kinase 4 -2.67507
PGLYRP2 peptidoglycan recognition protein 2 -2.67507
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 -2.67507
GDF6 growth differentiation factor 6 -2.67507
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 -2.67507
RAG2 recombination activating gene 2 -2.67507
CEL carboxyl ester lipase -2.65364
TNC tenascin C -2.65364
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 -2.65364
C2ORF92 chromosome 2 open reading frame 92 -2.62978
MYO7A myosin VIIA -2.59787
GAB1 GRB2-associated binding protein 1 -2.57187
SPAG1 sperm associated antigen 1 -2.54579
EPN2 epsin 2 -2.54005
TSHZ2 teashirt zinc finger homeobox 2 -2.49994
BCAP31 B-cell receptor-associated protein 31 -2.48037
ALOX12 arachidonate 12-lipoxygenase -2.43274
ZSCAN5A zinc finger and SCAN domain containing 5A -2.40865
MYRF myelin regulatory factor -2.40588
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 -2.3886
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.37001
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.36712
C1ORF52 chromosome 1 open reading frame 52 -2.34841
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -2.3261
SEC31B SEC31 homolog B (S. cerevisiae) -2.29405
NAP1L5 nucleosome assembly protein 1-like 5 -2.28062
STRADA STE20-related kinase adaptor alpha -2.27404
RNF144A ring finger protein 144A -2.2611
PCDHB16 protocadherin beta 16 -2.26072
GPHRA golgi pH regulator A -2.24254
MAK male germ cell-associated kinase -2.24254
TMED7 transmembrane emp24 protein transport domain containing 7 -2.23455
PTPRN protein tyrosine phosphatase, receptor type, N -2.23117
KLHL20 kelch-like family member 20 -2.216
SCLT1 sodium channel and clathrin linker 1 -2.20949
PTPRT protein tyrosine phosphatase, receptor type, T -2.1934
SV2C synaptic vesicle glycoprotein 2C -2.18051
MAP1A microtubule-associated protein 1A -2.18051
EMC4 ER membrane protein complex subunit 4 -2.18051
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -2.18051
CORO1C coronin, actin binding protein, 1C -2.18027
CEP43 centrosomal protein 43 -2.14733
LOC122539214 Zinc finger protein LOC122539214 -2.14402
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 -2.13787
DLGAP3 discs, large (Drosophila) homolog-associated protein 3 -2.1109
CBX1 chromobox homolog 1 -2.1109
ART5 ADP-ribosyltransferase 5 -2.0814
NPHP3 nephronophthisis 3 (adolescent) -2.07312
ZC3HAV1L zinc finger CCCH-type, antiviral 1-like -2.06657
PABIR3 PABIR family member 3 -2.05881
SLX4IP SLX4 interacting protein -2.05881
TAC4 tachykinin 4 (hemokinin) -2.04389
FAHD2B fumarylacetoacetate hydrolase domain containing 2B -2.04389
CNKSR2 connector enhancer of kinase suppressor of Ras 2 -2.03957
SAXO2 stabilizer of axonemal microtubules 2 -2.0315
ADGRB3 adhesion G protein-coupled receptor B3 -2.0315
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.0315
ZNF598 zinc finger protein 598 -2.01935
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein -2.01611
MCUB mitochondrial calcium uniporter dominant negative subunit beta -2.00636
KAT8 K(lysine) acetyltransferase 8 -2.00636
PHTF2 putative homeodomain transcription factor 2 -2.00575
SARAF store-operated calcium entry-associated regulatory factor -2.00061