MFE-296 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

288 genes with high or low expression in MFE-296 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 3.05709
BMPR1A bone morphogenetic protein receptor, type IA 2.83171
PDGFRL platelet-derived growth factor receptor-like 2.66325
LMO4 LIM domain only 4 2.65675
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.59985
GMFB glia maturation factor, beta 2.54563
DLX2 distal-less homeobox 2 2.40267
PTN pleiotrophin 2.32104
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 2.25243
PCM1 pericentriolar material 1 2.19929
MSX2 msh homeobox 2 2.16846
RAP2C RAP2C, member of RAS oncogene family 2.13553
ACTC1 actin, alpha, cardiac muscle 1 2.08489
AQR aquarius intron-binding spliceosomal factor 2.05856
CCDC68 coiled-coil domain containing 68 2.05689
EGFL6 EGF-like-domain, multiple 6 2.05635
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 2.05049
SNTG1 syntrophin, gamma 1 2.04885
UBA1 ubiquitin-like modifier activating enzyme 1 2.04865
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) 2.047
HAT1 histone acetyltransferase 1 2.04609
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 2.01038
MEST mesoderm specific transcript 2.00922
ZNF556 zinc finger protein 556 1.98417
SMAD6 SMAD family member 6 1.97731
RHOBTB1 Rho-related BTB domain containing 1 1.95137
RGS11 regulator of G-protein signaling 11 1.91442
MTUS1 microtubule associated tumor suppressor 1 1.898
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 1.89576
STAG1 stromal antigen 1 1.87786
CPA2 carboxypeptidase A2 (pancreatic) 1.87644
GPX7 glutathione peroxidase 7 1.81188
ATF7IP activating transcription factor 7 interacting protein 1.79794
WDR7 WD repeat domain 7 1.79713
PRPS2 phosphoribosyl pyrophosphate synthetase 2 1.78873
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 1.78639
HHLA3 HERV-H LTR-associating 3 1.7642
SNX7 sorting nexin 7 1.75923
TMEM35 transmembrane protein 35 1.73808
PDGFD platelet derived growth factor D 1.7265
THBS4 thrombospondin 4 1.70634
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.70567
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.70434
CASP5 caspase 5, apoptosis-related cysteine peptidase 1.70171
DGKI diacylglycerol kinase, iota 1.68702
KIFAP3 kinesin-associated protein 3 1.67516
IDE insulin-degrading enzyme 1.67107
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 1.66806
COPG2 coatomer protein complex, subunit gamma 2 1.66081
MAT1A methionine adenosyltransferase I, alpha 1.65708
FGL1 fibrinogen-like 1 1.65564
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 1.65535
PRDX2 peroxiredoxin 2 1.64516
ZNF606 zinc finger protein 606 1.64347
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 1.62915
NEK9 NIMA-related kinase 9 1.62832
STAG2 stromal antigen 2 1.61846
MPDZ multiple PDZ domain protein 1.61816
TRPM3 transient receptor potential cation channel, subfamily M, member 3 1.61563
CTCF CCCTC-binding factor (zinc finger protein) 1.61241
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding) 1.5941
PDS5B PDS5 cohesin associated factor B 1.58463
NAP1L2 nucleosome assembly protein 1-like 2 1.58415
BMP4 bone morphogenetic protein 4 1.57256
ACTN3 actinin, alpha 3 (gene/pseudogene) 1.53759
NFU1 NFU1 iron-sulfur cluster scaffold 1.52795
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 1.52594
WIF1 WNT inhibitory factor 1 1.52236
CADM4 cell adhesion molecule 4 1.5182
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 1.50935
ARID5B AT rich interactive domain 5B (MRF1-like) 1.50607
CDK16 cyclin-dependent kinase 16 1.50282
RAD51B RAD51 paralog B 1.48861
TXNRD3 thioredoxin reductase 3 1.48485
SH3BGR SH3 domain binding glutamate-rich protein 1.48063
ATP9A ATPase, class II, type 9A 1.47671
IVD isovaleryl-CoA dehydrogenase 1.46883
GLT8D2 glycosyltransferase 8 domain containing 2 1.46547
GCAT glycine C-acetyltransferase 1.46075
SAGE1 sarcoma antigen 1 1.46045
ABHD14A abhydrolase domain containing 14A 1.45959
DENND1A DENN/MADD domain containing 1A 1.45188
SERTAD2 SERTA domain containing 2 1.45067
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene) 1.45037
PRND prion protein 2 (dublet) 1.44814
ZNF45 zinc finger protein 45 1.43815
GALT galactose-1-phosphate uridylyltransferase 1.43397
TAL1 T-cell acute lymphocytic leukemia 1 1.42967
ZNF232 zinc finger protein 232 1.42915
TLE2 transducin-like enhancer of split 2 1.42148
ELAC1 elaC ribonuclease Z 1 1.42122
ECEL1 endothelin converting enzyme-like 1 1.42014
MAT2A methionine adenosyltransferase II, alpha 1.41916

low expression

Symbol Name Standardized Value
KRTAP4-7 keratin associated protein 4-7 -3.5369
JAK1 Janus kinase 1 -3.48077
IGL immunoglobulin lambda locus -3.35646
KRT84 keratin 84, type II -3.1063
HAMP hepcidin antimicrobial peptide -2.90292
ART1 ADP-ribosyltransferase 1 -2.81106
PNLIPRP2 pancreatic lipase-related protein 2 -2.76286
KRT35 keratin 35, type I -2.56338
MOG myelin oligodendrocyte glycoprotein -2.55138
CHML choroideremia-like (Rab escort protein 2) -2.53081
APCS amyloid P component, serum -2.51699
EPHB1 EPH receptor B1 -2.44962
PODNL1 podocan-like 1 -2.44217
SLAMF1 signaling lymphocytic activation molecule family member 1 -2.4416
FURIN furin (paired basic amino acid cleaving enzyme) -2.43813
INPP5F inositol polyphosphate-5-phosphatase F -2.41962
CDK17 cyclin-dependent kinase 17 -2.40611
IGLJ3 immunoglobulin lambda joining 3 -2.39983
SSX3 synovial sarcoma, X breakpoint 3 -2.39174
IL2RB interleukin 2 receptor, beta -2.33902
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -2.28179
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.22481
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -2.22207
VIPR2 vasoactive intestinal peptide receptor 2 -2.16849
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 -2.14908
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 -2.14047
TREM1 triggering receptor expressed on myeloid cells 1 -2.12663
HHLA1 HERV-H LTR-associating 1 -2.09656
HIST1H2BK histone cluster 1, H2bk -2.0918
A2M alpha-2-macroglobulin -2.08822
UGCG UDP-glucose ceramide glucosyltransferase -2.08081
MEGF6 multiple EGF-like-domains 6 -2.05863
KCTD12 potassium channel tetramerization domain containing 12 -2.04545
HBE1 hemoglobin, epsilon 1 -2.04186
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 -2.02272
PRSS22 protease, serine, 22 -2.02122
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -2.00845
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 -1.98791
RGS7 regulator of G-protein signaling 7 -1.98567
ZNF549 zinc finger protein 549 -1.9845
MED13L mediator complex subunit 13-like -1.9835
NPBWR2 neuropeptides B/W receptor 2 -1.97681
SCAND2P SCAN domain containing 2 pseudogene -1.96233
MAGEA3 melanoma antigen family A3 -1.95186
MLF1 myeloid leukemia factor 1 -1.94819
MTRF1L mitochondrial translational release factor 1-like -1.9357
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 -1.93503
MLH1 mutL homolog 1 -1.93182
PART1 prostate androgen-regulated transcript 1 (non-protein coding) -1.93019
DUSP4 dual specificity phosphatase 4 -1.92461
PTPRJ protein tyrosine phosphatase, receptor type, J -1.91532
AFF1 AF4/FMR2 family, member 1 -1.9077
ARHGAP24 Rho GTPase activating protein 24 -1.90225
EPHA5 EPH receptor A5 -1.90032
ZNF225 zinc finger protein 225 -1.88924
ARHGAP26 Rho GTPase activating protein 26 -1.88703
CXCL8 chemokine (C-X-C motif) ligand 8 -1.87962
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) -1.87797
USP12 ubiquitin specific peptidase 12 -1.87545
CHN2 chimerin 2 -1.86576
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 -1.86318
GRM3 glutamate receptor, metabotropic 3 -1.86309
ATXN3L ataxin 3-like -1.8598
CETN1 centrin, EF-hand protein, 1 -1.85899
PTK2B protein tyrosine kinase 2 beta -1.85608
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -1.85032
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -1.84545
KRT38 keratin 38, type I -1.8448
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -1.84144
LOC400655 uncharacterized LOC400655 -1.83222
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled -1.82968
CD96 CD96 molecule -1.81599
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -1.81157
CYTH1 cytohesin 1 -1.80162
DRD5 dopamine receptor D5 -1.798
CUTC cutC copper transporter -1.79392
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.78954
KLK7 kallikrein-related peptidase 7 -1.78925
ACSL6 acyl-CoA synthetase long-chain family member 6 -1.7875
SCG3 secretogranin III -1.78737
PNMT phenylethanolamine N-methyltransferase -1.78437
SIGLEC7 sialic acid binding Ig-like lectin 7 -1.77611
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -1.77205
IFNA10 interferon, alpha 10 -1.76762
TINAGL1 tubulointerstitial nephritis antigen-like 1 -1.75505
HAPLN1 hyaluronan and proteoglycan link protein 1 -1.75323
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -1.7526
MED26 mediator complex subunit 26 -1.74045
HOXA5 homeobox A5 -1.73555
CA4 carbonic anhydrase IV -1.73403
TMPRSS6 transmembrane protease, serine 6 -1.73381
CDH4 cadherin 4, type 1, R-cadherin (retinal) -1.72813
AKR1D1 aldo-keto reductase family 1, member D1 -1.72562
NLGN4X neuroligin 4, X-linked -1.72485
NR0B1 nuclear receptor subfamily 0, group B, member 1 -1.72067
MOGAT2 monoacylglycerol O-acyltransferase 2 -1.72057
TFAM transcription factor A, mitochondrial -1.72048
SCRG1 stimulator of chondrogenesis 1 -1.71784
PDZD7 PDZ domain containing 7 -1.71624
PRDM12 PR domain containing 12 -1.71246
RPE65 retinal pigment epithelium-specific protein 65kDa -1.70426
GYS2 glycogen synthase 2 (liver) -1.69229
SELPLG selectin P ligand -1.69158
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -1.68866
MAN2A1 mannosidase, alpha, class 2A, member 1 -1.6827
CTSE cathepsin E -1.67983
CIITA class II, major histocompatibility complex, transactivator -1.67881
RAB40A RAB40A, member RAS oncogene family -1.67829
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -1.67599
IHH indian hedgehog -1.67457
PTGER3 prostaglandin E receptor 3 (subtype EP3) -1.66996
PECAM1 platelet/endothelial cell adhesion molecule 1 -1.66861
TTI1 TELO2 interacting protein 1 -1.66111
DENND3 DENN/MADD domain containing 3 -1.66107
IL24 interleukin 24 -1.65558
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -1.65346
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 -1.649
EPM2AIP1 EPM2A (laforin) interacting protein 1 -1.64702
CDX2 caudal type homeobox 2 -1.62575
PGC progastricsin (pepsinogen C) -1.61841
PNPLA4 patatin-like phospholipase domain containing 4 -1.61386
AQP6 aquaporin 6, kidney specific -1.60285
BNC2 basonuclin 2 -1.58905
SPN sialophorin -1.58856
PAGE1 P antigen family, member 1 (prostate associated) -1.58364
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 -1.5832
KRT33A keratin 33A, type I -1.58319
PPBPP2 pro-platelet basic protein pseudogene 2 -1.57802
VSNL1 visinin-like 1 -1.57665
PTPRR protein tyrosine phosphatase, receptor type, R -1.57618
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -1.57614
CBLN1 cerebellin 1 precursor -1.57195
TRPC4 transient receptor potential cation channel, subfamily C, member 4 -1.57118
IFNA14 interferon, alpha 14 -1.57102
TRH thyrotropin-releasing hormone -1.57045
CXCL12 chemokine (C-X-C motif) ligand 12 -1.56829
PTPRC protein tyrosine phosphatase, receptor type, C -1.56805
PDZK1IP1 PDZK1 interacting protein 1 -1.56764
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -1.55714
PIEZO2 piezo-type mechanosensitive ion channel component 2 -1.55426
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D -1.55108
STAT4 signal transducer and activator of transcription 4 -1.55048
PCDHB1 protocadherin beta 1 -1.55019
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -1.54992
LOR loricrin -1.54479
NR4A3 nuclear receptor subfamily 4, group A, member 3 -1.53753
KSR1 kinase suppressor of ras 1 -1.5298
EMCN endomucin -1.52973
H2BFS H2B histone family, member S (pseudogene) -1.52915
MSMO1 methylsterol monooxygenase 1 -1.52253
ADCY8 adenylate cyclase 8 (brain) -1.52178
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -1.51873
CD2 CD2 molecule -1.51672
SERP1 stress-associated endoplasmic reticulum protein 1 -1.51465
ZNF471 zinc finger protein 471 -1.51263
COL21A1 collagen, type XXI, alpha 1 -1.5123
NPY4R neuropeptide Y receptor Y4 -1.50876
FOXP1 forkhead box P1 -1.50778
PARP6 poly (ADP-ribose) polymerase family, member 6 -1.50489
OTUD7B OTU deubiquitinase 7B -1.50432
EVI2A ecotropic viral integration site 2A -1.50361
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -1.48811
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 -1.4881
NGB neuroglobin -1.48754
PADI1 peptidyl arginine deiminase, type I -1.48583
F9 coagulation factor IX -1.48569
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 -1.48229
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -1.47855
CHRM2 cholinergic receptor, muscarinic 2 -1.47768
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 -1.47757
NRIP2 nuclear receptor interacting protein 2 -1.47361
GPR25 G protein-coupled receptor 25 -1.47009
NTSR1 neurotensin receptor 1 (high affinity) -1.47007
ANOS1 anosmin 1 -1.46953
ASIC3 acid sensing (proton gated) ion channel 3 -1.46701
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -1.45906
BEAN1 brain expressed, associated with NEDD4, 1 -1.45839
ADH6 alcohol dehydrogenase 6 (class V) -1.45569
IRF4 interferon regulatory factor 4 -1.45411
PAMR1 peptidase domain containing associated with muscle regeneration 1 -1.45011
CLCN1 chloride channel, voltage-sensitive 1 -1.44861
FGF6 fibroblast growth factor 6 -1.44842
ASCL3 achaete-scute family bHLH transcription factor 3 -1.44559
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -1.44027
ANKH ANKH inorganic pyrophosphate transport regulator -1.43727
BNC1 basonuclin 1 -1.43339
STMN4 stathmin-like 4 -1.43268
POU6F2 POU class 6 homeobox 2 -1.42694
PDK4 pyruvate dehydrogenase kinase, isozyme 4 -1.42568
GJA4 gap junction protein, alpha 4, 37kDa -1.42507
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 -1.42482
PTPRG protein tyrosine phosphatase, receptor type, G -1.42134
GNG13 guanine nucleotide binding protein (G protein), gamma 13 -1.42088
GRM1 glutamate receptor, metabotropic 1 -1.41821
PROZ protein Z, vitamin K-dependent plasma glycoprotein -1.41788