MFM-223 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Breast Carcinoma Metastasis (Cell Model Passports, SIDM00332)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00332
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Genes

199 proteins associated with the cell line MFM-223 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ADK adenosine kinase
AIP aryl hydrocarbon receptor interacting protein
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA11 annexin A11
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BABAM1 BRISC and BRCA1 A complex member 1
C19ORF53 chromosome 19 open reading frame 53
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CC2D1A coiled-coil and C2 domain containing 1A
CCDC124 coiled-coil domain containing 124
CCDC6 coiled-coil domain containing 6
CHMP2A charged multivesicular body protein 2A
CHMP4B charged multivesicular body protein 4B
CLTB clathrin, light chain B
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
COG3 component of oligomeric golgi complex 3
COMT catechol-O-methyltransferase
COMTD1 catechol-O-methyltransferase domain containing 1
CORO1B coronin, actin binding protein, 1B
CRABP2 cellular retinoic acid binding protein 2
CRTC1 CREB regulated transcription coactivator 1
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EPN2 epsin 2
EPN3 epsin 3
ERLIN2 ER lipid raft associated 2
FBXO22 F-box protein 22
FILIP1 filamin A interacting protein 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GBP1 guanylate binding protein 1, interferon-inducible
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GOLGA5 golgin A5
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GORASP2 golgi reassembly stacking protein 2, 55kDa
GYG1 glycogenin 1
HDGF hepatoma-derived growth factor
HEBP2 heme binding protein 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ILVBL ilvB (bacterial acetolactate synthase)-like
LMCD1 LIM and cysteine-rich domains 1
LOC100507393 putative uncharacterized protein FLJ44672-like
LOC100653005
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAGED2 melanoma antigen family D2
MAP1S microtubule-associated protein 1S
MAP2K3 mitogen-activated protein kinase kinase 3
MCTP1 multiple C2 domains, transmembrane 1
MEA1 male-enhanced antigen 1
MTA3 metastasis associated 1 family, member 3
MYO9B myosin IXB
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NAGK N-acetylglucosamine kinase
NANS N-acetylneuraminic acid synthase
NDFIP1 Nedd4 family interacting protein 1
NLGN1 neuroligin 1
NOTCH4 notch 4
NOVA2 neuro-oncological ventral antigen 2
NR2C2AP nuclear receptor 2C2-associated protein
PDCD6IP programmed cell death 6 interacting protein
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PGLS 6-phosphogluconolactonase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PPT1 palmitoyl-protein thioesterase 1
PRRC1 proline-rich coiled-coil 1
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB5A RAB5A, member RAS oncogene family
RAD23A RAD23 homolog A (S. cerevisiae)
RALYL RALY RNA binding protein-like
RBPJ recombination signal binding protein for immunoglobulin kappa J region
S100A13 S100 calcium binding protein A13
S100A16 S100 calcium binding protein A16
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24C SEC24 family member C
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIDT1 SID1 transmembrane family, member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
STK24 serine/threonine kinase 24
SUN5 Sad1 and UNC84 domain containing 5
SYAP1 synapse associated protein 1
TATDN1 TatD DNase domain containing 1
TFG TRK-fused gene
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM11 transmembrane protein 11
TMEM65 transmembrane protein 65
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
UBA1 ubiquitin-like modifier activating enzyme 1
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
VCL vinculin
VDAC2 voltage-dependent anion channel 2
ZFP36L1 ZFP36 ring finger protein-like 1

Symbol Name
ABT1 activator of basal transcription 1
ADPGK ADP-dependent glucokinase
AGK acylglycerol kinase
BRAT1 BRCA1-associated ATM activator 1
CCDC86 coiled-coil domain containing 86
CDKN2AIP CDKN2A interacting protein
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHUK conserved helix-loop-helix ubiquitous kinase
COX5A cytochrome c oxidase subunit Va
COX5B cytochrome c oxidase subunit Vb
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
COX6C cytochrome c oxidase subunit VIc
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
COX7C cytochrome c oxidase subunit VIIc
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe)
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
GFM2 G elongation factor, mitochondrial 2
GPR35 G protein-coupled receptor 35
GSTM2 glutathione S-transferase mu 2 (muscle)
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
INO80B INO80 complex subunit B
ITSN1 intersectin 1 (SH3 domain protein)
IVD isovaleryl-CoA dehydrogenase
KHNYN KH and NYN domain containing
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
LOC105371745 uncharacterized LOC105371745
LRRC34 leucine rich repeat containing 34
METTL16 methyltransferase like 16
MKKS McKusick-Kaufman syndrome
MRPL1 mitochondrial ribosomal protein L1
MRPL14 mitochondrial ribosomal protein L14
MRPL18 mitochondrial ribosomal protein L18
MRPL19 mitochondrial ribosomal protein L19
MRPL21 mitochondrial ribosomal protein L21
MRPL32 mitochondrial ribosomal protein L32
MRPL39 mitochondrial ribosomal protein L39
MRPL41 mitochondrial ribosomal protein L41
MRPL43 mitochondrial ribosomal protein L43
MRPS23 mitochondrial ribosomal protein S23
MRPS24 mitochondrial ribosomal protein S24
MRPS28 mitochondrial ribosomal protein S28
MRPS33 mitochondrial ribosomal protein S33
MT-CO2 cytochrome c oxidase subunit II
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NDUFA4 NDUFA4, mitochondrial complex associated
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NEDE nephropathy, progressive, with deafness
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NGRN neugrin, neurite outgrowth associated
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOM1 nucleolar protein with MIF4G domain 1
OR4K3 olfactory receptor, family 4, subfamily K, member 3 (gene/pseudogene)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROM2 prominin 2
PVR poliovirus receptor
RPL7L1 ribosomal protein L7-like 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRP1 ribosomal RNA processing 1
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae)
SIRT3 sirtuin 3
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SP3 Sp3 transcription factor
TDP2 tyrosyl-DNA phosphodiesterase 2
TECR trans-2,3-enoyl-CoA reductase
TERF2 telomeric repeat binding factor 2
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TRIM9 tripartite motif containing 9
TXNIP thioredoxin interacting protein
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
UQCRB ubiquinol-cytochrome c reductase binding protein
UQCRC1 ubiquinol-cytochrome c reductase core protein I
UQCRC2 ubiquinol-cytochrome c reductase core protein II
WDR74 WD repeat domain 74
WDR75 WD repeat domain 75
WDR92 WD repeat domain 92
YES1 YES proto-oncogene 1, Src family tyrosine kinase