Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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200 genes differentially expressed following the MG-262-7079 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD3 | abhydrolase domain containing 3 |
ADM | adrenomedullin |
ALOXE3 | arachidonate lipoxygenase 3 |
ANKLE2 | ankyrin repeat and LEM domain containing 2 |
ARG2 | arginase 2 |
ATF3 | activating transcription factor 3 |
BAG3 | BCL2-associated athanogene 3 |
BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
CARS | cysteinyl-tRNA synthetase |
CDC6 | cell division cycle 6 |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
CLK1 | CDC-like kinase 1 |
CLU | clusterin |
CRYAB | crystallin, alpha B |
CSRP2 | cysteine and glycine-rich protein 2 |
CTGF | connective tissue growth factor |
CXCL3 | chemokine (C-X-C motif) ligand 3 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DDIT3 | DNA-damage-inducible transcript 3 |
DDIT4 | DNA-damage-inducible transcript 4 |
DFNB31 | deafness, autosomal recessive 31 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
DUSP1 | dual specificity phosphatase 1 |
DUSP2 | dual specificity phosphatase 2 |
EGF | epidermal growth factor |
FAM129A | family with sequence similarity 129, member A |
FAM46A | family with sequence similarity 46, member A |
FKBP4 | FK506 binding protein 4, 59kDa |
GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
GADD45B | growth arrest and DNA-damage-inducible, beta |
GPN1 | GPN-loop GTPase 1 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
HMOX1 | heme oxygenase 1 |
HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA4 | heat shock 70kDa protein 4 |
HSPA4L | heat shock 70kDa protein 4-like |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPB1 | heat shock 27kDa protein 1 |
HSPB8 | heat shock 22kDa protein 8 |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
IER5 | immediate early response 5 |
IL11 | interleukin 11 |
IL17RB | interleukin 17 receptor B |
IL1RL1 | interleukin 1 receptor-like 1 |
IL7R | interleukin 7 receptor |
JUN | jun proto-oncogene |
KLHL25 | kelch-like family member 25 |
KRT6A | keratin 6A, type II |
LDLR | low density lipoprotein receptor |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MARS | methionyl-tRNA synthetase |
MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
MERTK | MER proto-oncogene, tyrosine kinase |
MRPL18 | mitochondrial ribosomal protein L18 |
NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
NKRF | NFKB repressing factor |
OASL | 2'-5'-oligoadenylate synthetase-like |
P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
PELI1 | pellino E3 ubiquitin protein ligase 1 |
PGF | placental growth factor |
PLAUR | plasminogen activator, urokinase receptor |
PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
PRKD1 | protein kinase D1 |
RFPL2 | ret finger protein-like 2 |
RND1 | Rho family GTPase 1 |
RUNX3 | runt-related transcription factor 3 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
SMC4 | structural maintenance of chromosomes 4 |
SQSTM1 | sequestosome 1 |
STC2 | stanniocalcin 2 |
SUGP1 | SURP and G patch domain containing 1 |
TMEM2 | transmembrane protein 2 |
TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
TRIM26 | tripartite motif containing 26 |
TSPYL2 | TSPY-like 2 |
UBB | ubiquitin B |
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
ZFP36 | ZFP36 ring finger protein |
ZNF473 | zinc finger protein 473 |
ZNF804A | zinc finger protein 804A |
Symbol | Name |
---|---|
ABI3BP | ABI family, member 3 (NESH) binding protein |
ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
ARL4A | ADP-ribosylation factor-like 4A |
B3GNT1 | |
BBS10 | Bardet-Biedl syndrome 10 |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BHLHE41 | basic helix-loop-helix family, member e41 |
BOLA1 | bolA family member 1 |
C11ORF68 | chromosome 11 open reading frame 68 |
CAPN5 | calpain 5 |
CBR4 | carbonyl reductase 4 |
CEMIP | cell migration inducing protein, hyaluronan binding |
CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
CTAGE9 | CTAGE family, member 9 |
CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
DEPDC1 | DEP domain containing 1 |
DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
DUSP4 | dual specificity phosphatase 4 |
EFNA1 | ephrin-A1 |
ERF | Ets2 repressor factor |
FADD | Fas (TNFRSF6)-associated via death domain |
FJX1 | four jointed box 1 (Drosophila) |
FZD2 | frizzled class receptor 2 |
FZD8 | frizzled class receptor 8 |
GLI3 | GLI family zinc finger 3 |
GRHL2 | grainyhead-like 2 (Drosophila) |
GRPR | gastrin-releasing peptide receptor |
H1F0 | H1 histone family, member 0 |
H1FX | H1 histone family, member X |
HAS2 | hyaluronan synthase 2 |
HDAC7 | histone deacetylase 7 |
HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
HIST1H2AC | histone cluster 1, H2ac |
HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
HK2 | hexokinase 2 |
HMGA2 | high mobility group AT-hook 2 |
HOXA5 | homeobox A5 |
HYAL2 | hyaluronoglucosaminidase 2 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
IL33 | interleukin 33 |
INHBB | inhibin, beta B |
KIFC1 | kinesin family member C1 |
KLF10 | Kruppel-like factor 10 |
LIF | leukemia inhibitory factor |
LIG4 | ligase IV, DNA, ATP-dependent |
LPAR6 | lysophosphatidic acid receptor 6 |
LPCAT1 | lysophosphatidylcholine acyltransferase 1 |
LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
MCM3AP-AS1 | MCM3AP antisense RNA 1 |
MNT | MAX network transcriptional repressor |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
MXD3 | MAX dimerization protein 3 |
NDE1 | nudE neurodevelopment protein 1 |
NPR3 | natriuretic peptide receptor 3 |
NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
PEX11B | peroxisomal biogenesis factor 11 beta |
PHC2 | polyhomeotic homolog 2 (Drosophila) |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
PIAS3 | protein inhibitor of activated STAT, 3 |
PLAU | plasminogen activator, urokinase |
PPAP2B | phosphatidic acid phosphatase type 2B |
PPARG | peroxisome proliferator-activated receptor gamma |
PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
PSRC1 | proline/serine-rich coiled-coil 1 |
PTGFR | prostaglandin F receptor (FP) |
PTX3 | pentraxin 3, long |
PYCARD | PYD and CARD domain containing |
RAB20 | RAB20, member RAS oncogene family |
RANBP6 | RAN binding protein 6 |
RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
RIN2 | Ras and Rab interactor 2 |
RSAD1 | radical S-adenosyl methionine domain containing 1 |
SCO2 | SCO2 cytochrome c oxidase assembly protein |
SETD6 | SET domain containing 6 |
SHROOM2 | shroom family member 2 |
SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
SOX9 | SRY (sex determining region Y)-box 9 |
SPATA7 | spermatogenesis associated 7 |
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
ST5 | suppression of tumorigenicity 5 |
STX1A | syntaxin 1A (brain) |
TENM4 | teneurin transmembrane protein 4 |
TMEM177 | transmembrane protein 177 |
TMEM187 | transmembrane protein 187 |
TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TSPAN15 | tetraspanin 15 |
VASP | vasodilator-stimulated phosphoprotein |
WDR5B | WD repeat domain 5B |
ZBED8 | zinc finger, BED-type containing 8 |
ZHX2 | zinc fingers and homeoboxes 2 |
ZNF248 | zinc finger protein 248 |
ZNF33B | zinc finger protein 33B |