MICOS13 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mitochondrial contact site and cristae organizing system subunit 13 (NCBI Entrez Gene Database, 125988)
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Genes

331 genes differentially expressed following the MICOS13 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RPS14 ribosomal protein S14 2.90259
CD6 CD6 molecule 2.90259
AGTR1 angiotensin II receptor, type 1 2.90259
INHBC inhibin, beta C 2.90259
SOX1 SRY (sex determining region Y)-box 1 2.90259
VWA5B2 von Willebrand factor A domain containing 5B2 2.90259
SACK1A scaffolding CK1 anchoring protein A 2.90259
GPR52 G protein-coupled receptor 52 2.90259
DUXB double homeobox B 2.90259
SLC46A2 solute carrier family 46, member 2 2.90259
HRH4 histamine receptor H4 2.90259
GJA3 gap junction protein, alpha 3, 46kDa 2.90259
GJA9 gap junction protein, alpha 9, 59kDa 2.90259
KLHL31 kelch-like family member 31 2.90259
HHEX hematopoietically expressed homeobox 2.90259
OR2A25 olfactory receptor, family 2, subfamily A, member 25 2.90259
RAET1L retinoic acid early transcript 1L 2.90259
RAET1G retinoic acid early transcript 1G 2.90259
HBA2 hemoglobin, alpha 2 2.90259
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.90259
CFHR3 complement factor H-related 3 2.90259
MYT1L myelin transcription factor 1-like 2.90259
RAX retina and anterior neural fold homeobox 2.90259
PCDHB1 protocadherin beta 1 2.90259
ELMO3 engulfment and cell motility 3 2.90259
ZNF556 zinc finger protein 556 2.90259
C1ORF141 chromosome 1 open reading frame 141 2.90259
LRRC61 leucine rich repeat containing 61 2.90259
TREML1 triggering receptor expressed on myeloid cells-like 1 2.90259
CRYGN crystallin, gamma N 2.90259
LBX2 ladybird homeobox 2 2.90259
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 2.90259
MYO1A myosin IA 2.90259
SPHK1 sphingosine kinase 1 2.90259
SUSD2 sushi domain containing 2 2.90259
AANAT aralkylamine N-acetyltransferase 2.90259
CORO1A coronin, actin binding protein, 1A 2.90259
TMEM151A transmembrane protein 151A 2.90259
PGBDF plakoglobin binding and degradation factor 2.90259
CNTNAP4 contactin associated protein-like 4 2.90259
AMTN amelotin 2.90259
CLEC19A C-type lectin domain family 19, member A 2.90259
LRRC52 leucine rich repeat containing 52 2.90259
GDNF glial cell derived neurotrophic factor 2.90259
MFAP5 microfibrillar associated protein 5 2.90259
GPR22 G protein-coupled receptor 22 2.90259
EVPL envoplakin 2.90259
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.90259
WDR97 WD repeat domain 97 2.90259
CFAP65 cilia and flagella associated protein 65 2.90259
CCDC9B coiled-coil domain containing 9B 2.90259
DEFB108B defensin, beta 108B 2.90259
ERVW-1 endogenous retrovirus group W, member 1 2.90259
GBP4 guanylate binding protein 4 2.90259
GBP6 guanylate binding protein family, member 6 2.90259
KY kyphoscoliosis peptidase 2.90259
YIPF7 Yip1 domain family, member 7 2.90259
GARIN1A golgi associated RAB2 interactor 1A 2.90259
CFAP206 cilia and flagella associated protein 206 2.90259
ODAPH odontogenesis associated phosphoprotein 2.90259
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 2.90259
TEKTL1 tektin like 1 2.90259
FAM240A family with sequence similarity 240 member A 2.90259
LRRC8C-DT LRRC8C divergent transcript 2.90259
CPNE8-AS1 CPNE8 antisense RNA 1 2.90259
IRF2-DT IRF2 divergent transcript 2.90259
CTXND1 cortexin domain containing 1 2.90259
SPAAR small regulatory polypeptide of amino acid response 2.90259
ARMH2 armadillo like helical domain containing 2 2.90259
OTOR otoraplin 2.90259
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 2.90259
ANO3 anoctamin 3 2.90259
GJD2 gap junction protein, delta 2, 36kDa 2.90259
GJD4 gap junction protein, delta 4, 40.1kDa 2.90259
IFNL1 interferon, lambda 1 2.90259
GZMM granzyme M (lymphocyte met-ase 1) 2.90259
OVOL3 ovo-like zinc finger 3 2.90259
NPIPB9 nuclear pore complex interacting protein family, member B9 2.90259
CXCL16 chemokine (C-X-C motif) ligand 16 2.90259
MSX1 msh homeobox 1 2.90259
FAM43A family with sequence similarity 43, member A 2.90259
C9 complement component 9 2.90259
PGA5 pepsinogen 5, group I (pepsinogen A) 2.90259
ABHD15 abhydrolase domain containing 15 2.90259
RPS5 ribosomal protein S5 2.90259
BDKRB2 bradykinin receptor B2 2.90259
WNT16 wingless-type MMTV integration site family, member 16 2.90259
DOK2 docking protein 2, 56kDa 2.90259
TSPAN1 tetraspanin 1 2.90259
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 2.90259
GATA3 GATA binding protein 3 2.90259
ZNF683 zinc finger protein 683 2.90259
GDF6 growth differentiation factor 6 2.90259
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.90259
GRM1 glutamate receptor, metabotropic 1 2.90259
CLIC5 chloride intracellular channel 5 2.90259
CDHR4 cadherin-related family member 4 2.90259
LRRIQ3 leucine-rich repeats and IQ motif containing 3 2.90259
POU1F1 POU class 1 homeobox 1 2.90259
RNASE11 ribonuclease, RNase A family, 11 (non-active) 2.90259
TBC1D10C TBC1 domain family, member 10C 2.90259
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.90259
F2RL3 coagulation factor II (thrombin) receptor-like 3 2.90259
C2CD4A C2 calcium-dependent domain containing 4A 2.90259
CRHR1 corticotropin releasing hormone receptor 1 2.90259
GCOM1 GRINL1A complex locus 1 2.90259
ESYT1 extended synaptotagmin-like protein 1 2.90259
CXCR5 chemokine (C-X-C motif) receptor 5 2.90259
CNTF ciliary neurotrophic factor 2.90259
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 2.90259
ZNF703 zinc finger protein 703 2.90259
TUBA8 tubulin, alpha 8 2.90259
EDN3 endothelin 3 2.90259
GPR12 G protein-coupled receptor 12 2.90259
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 2.90259
C11ORF91 chromosome 11 open reading frame 91 2.90259
TSLP thymic stromal lymphopoietin 2.90259
TEKT5 tektin 5 2.90259
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.90259
RBBP8NL RBBP8 N-terminal like 2.90259
NLRP14 NLR family, pyrin domain containing 14 2.90259
MSMP microseminoprotein, prostate associated 2.90259
ERVV-1 endogenous retrovirus group V, member 1 2.90259
GPR150 G protein-coupled receptor 150 2.90259
HPGDS hematopoietic prostaglandin D synthase 2.90259
C10ORF105 chromosome 10 open reading frame 105 2.90259
WNT4 wingless-type MMTV integration site family, member 4 2.90259
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.90259
PSG8 pregnancy specific beta-1-glycoprotein 8 2.90259
NCR3 natural cytotoxicity triggering receptor 3 2.90259
ZIM2 zinc finger, imprinted 2 2.90259
ITGA11 integrin, alpha 11 2.90259
GADD45G growth arrest and DNA-damage-inducible, gamma 2.90259
BSPH1 binder of sperm protein homolog 1 2.90259
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 2.90259
ARL13A ADP-ribosylation factor-like 13A 2.90259
TG thyroglobulin 2.90259
DMRT1 doublesex and mab-3 related transcription factor 1 2.90259
XIRP2 xin actin binding repeat containing 2 2.90259
PRH2 proline-rich protein HaeIII subfamily 2 2.90259
CFI complement factor I 2.90259
FADS6 fatty acid desaturase 6 2.90259
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 2.90259
SLC9C2 solute carrier family 9, member C2 (putative) 2.90259
MMP13 matrix metallopeptidase 13 2.90259
THEM5 thioesterase superfamily member 5 2.90259
LRRC38 leucine rich repeat containing 38 2.90259
POU3F2 POU class 3 homeobox 2 2.90259
CIB3 calcium and integrin binding family member 3 2.90259
AQP1 aquaporin 1 (Colton blood group) 2.90259
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 2.90259
CARNS1 carnosine synthase 1 2.90259
MT1A metallothionein 1A 2.90259
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 2.90259
C9ORF57 chromosome 9 open reading frame 57 2.90259
TMEM132D transmembrane protein 132D 2.90259
FXYD3 FXYD domain containing ion transport regulator 3 2.90259
ESAM endothelial cell adhesion molecule 2.90259
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.90259
CLIC3 chloride intracellular channel 3 2.90259
CLEC2B C-type lectin domain family 2, member B 2.90259
NRGN neurogranin (protein kinase C substrate, RC3) 2.90259
NLRP5 NLR family, pyrin domain containing 5 2.90259
LPO lactoperoxidase 2.90259
ANGPTL3 angiopoietin-like 3 2.90259
TSPAN32 tetraspanin 32 2.90259
CSF3R colony stimulating factor 3 receptor (granulocyte) 2.90259
STOML3 stomatin (EPB72)-like 3 2.90259
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 2.8914
WSCD1 WSC domain containing 1 2.88272
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 2.87128
SCRG1 stimulator of chondrogenesis 1 2.86552
LEKR1 leucine, glutamate and lysine rich 1 2.86552
MTRFR mitochondrial translation release factor in rescue 2.85004
SHOC1 shortage in chiasmata 1 2.83147
C19ORF73 chromosome 19 open reading frame 73 2.7983
CXXC5 CXXC finger protein 5 2.70954
FRRS1 ferric-chelate reductase 1 2.68795
NOTCH2NLC notch 2 N-terminal like C 2.65509
ZNF652 zinc finger protein 652 2.63596
XDH xanthine dehydrogenase 2.59191
AR androgen receptor 2.54412
TMEM158 transmembrane protein 158 (gene/pseudogene) 2.54289
KIAA0930 KIAA0930 2.54055
DNAH1 dynein, axonemal, heavy chain 1 2.52161
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.45938
ZNF446 zinc finger protein 446 2.43037
SIN3B SIN3 transcription regulator family member B 2.41648
MRPL4 mitochondrial ribosomal protein L4 2.40811
RPS10 ribosomal protein S10 2.40291
UBA2 ubiquitin-like modifier activating enzyme 2 2.38536
TRIL TLR4 interactor with leucine-rich repeats 2.38536
THOP1 thimet oligopeptidase 1 2.3667
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.36532
BRICD5 BRICHOS domain containing 5 2.36532
ZRANB3 zinc finger, RAN-binding domain containing 3 2.36532
SRGAP2B SLIT-ROBO Rho GTPase activating protein 2B 2.36206
KRT18 keratin 18, type I 2.29129
AUTS2 autism susceptibility candidate 2 2.2889
GCFC2 GC-rich sequence DNA-binding factor 2 2.23659
PREPL prolyl endopeptidase-like 2.19941
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.19696
LTBP4 latent transforming growth factor beta binding protein 4 2.19689
LYAR Ly1 antibody reactive 2.14898
TIMM29 translocase of inner mitochondrial membrane 29 2.13895
TUBB tubulin, beta class I 2.12554
DCLK1 doublecortin-like kinase 1 2.1132
SELENOH selenoprotein H 2.11095
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 2.10787
EXOC3L2 exocyst complex component 3-like 2 2.10787
SYT4 synaptotagmin IV 2.10787
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 2.09913
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.09413
ISOC1 isochorismatase domain containing 1 2.08985
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 2.08211
EIF3K eukaryotic translation initiation factor 3, subunit K 2.06585
CPLX2 complexin 2 2.05833
H2AC14 H2A clustered histone 14 2.05594
AKAP10 A kinase (PRKA) anchor protein 10 2.04378
HINT3 histidine triad nucleotide binding protein 3 2.03821
TMEM69 transmembrane protein 69 2.02522
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 2.02391
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.02391
TMEM45A transmembrane protein 45A 2.0107
D2HGDH D-2-hydroxyglutarate dehydrogenase 2.00861
LIG1 ligase I, DNA, ATP-dependent 2.00861

decreased expression

Symbol Name Standardized Value
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -2.90259
C22ORF23 chromosome 22 open reading frame 23 -2.90259
ELL3 elongation factor RNA polymerase II-like 3 -2.90259
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -2.90259
WDR5B WD repeat domain 5B -2.90259
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 -2.90259
HIST1H2BI histone cluster 1, H2bi -2.90259
NTF4 neurotrophin 4 -2.90259
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) -2.90259
IPO13 importin 13 -2.90259
SPMIP6 sperm microtubule inner protein 6 -2.90259
CPHXL2 cytoplasmic polyadenylated homeobox like 2 -2.90259
VDAC3 voltage-dependent anion channel 3 -2.90259
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.90259
RAB42 RAB42, member RAS oncogene family -2.89753
SPNS2 spinster homolog 2 (Drosophila) -2.8914
LIN7B lin-7 homolog B (C. elegans) -2.88272
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 -2.87894
PITX3 paired-like homeodomain 3 -2.87128
RAMACL RNA guanine-7 methyltransferase activating subunit like -2.87128
CBLIF cobalamin binding intrinsic factor -2.87128
REEP1 receptor accessory protein 1 -2.87128
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -2.87128
OR10A2 olfactory receptor, family 10, subfamily A, member 2 -2.87128
TMEM121 transmembrane protein 121 -2.87128
DLX4 distal-less homeobox 4 -2.87128
FAM131C family with sequence similarity 131, member C -2.87128
RGPD1 RANBP2-like and GRIP domain containing 1 -2.87128
GATA2 GATA binding protein 2 -2.87128
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.87128
TRPC6 transient receptor potential cation channel, subfamily C, member 6 -2.87128
AKR1C2 aldo-keto reductase family 1, member C2 -2.87128
ANKRD42-DT ANKRD42 divergent transcript -2.87128
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -2.87128
HSPA1L heat shock 70kDa protein 1-like -2.87128
RAD21L1 RAD21-like 1 (S. pombe) -2.87128
ADAM8 ADAM metallopeptidase domain 8 -2.87128
CCDC159 coiled-coil domain containing 159 -2.87128
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -2.87128
C2CD4D C2 calcium-dependent domain containing 4D -2.87128
B9D2 B9 protein domain 2 -2.87128
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -2.87128
HLA-G major histocompatibility complex, class I, G -2.87128
ZNF843 zinc finger protein 843 -2.87128
MLIP muscular LMNA-interacting protein -2.87128
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 -2.87128
F10 coagulation factor X -2.87128
BHMT betaine--homocysteine S-methyltransferase -2.87128
POTEJ POTE ankyrin domain family, member J -2.87128
ZNF638 zinc finger protein 638 -2.85707
CD164L2 CD164 sialomucin-like 2 -2.72695
CALCOCO2 calcium binding and coiled-coil domain 2 -2.65526
BBS5 Bardet-Biedl syndrome 5 -2.59191
ALOX12 arachidonate 12-lipoxygenase -2.59191
ZNF253 zinc finger protein 253 -2.59191
INSYN1 inhibitory synaptic factor 1 -2.59191
PAMR1 peptidase domain containing associated with muscle regeneration 1 -2.51627
TMEM184B transmembrane protein 184B -2.50527
MAGED1 melanoma antigen family D1 -2.43579
SLC35G1 solute carrier family 35, member G1 -2.42842
SH2D5 SH2 domain containing 5 -2.38536
CCDC63 coiled-coil domain containing 63 -2.38536
CBY3 chibby homolog 3 (Drosophila) -2.38536
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -2.38403
SCNN1A sodium channel, non voltage gated 1 alpha subunit -2.35756
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -2.35226
CDC42SE1 CDC42 small effector 1 -2.35226
CAB39L calcium binding protein 39-like -2.34085
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -2.34009
NUMA1 nuclear mitotic apparatus protein 1 -2.33458
PCSK7 proprotein convertase subtilisin/kexin type 7 -2.33458
SRP19 signal recognition particle 19kDa -2.32279
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -2.29951
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 -2.29951
FAAH fatty acid amide hydrolase -2.294
C1ORF54 chromosome 1 open reading frame 54 -2.294
ZBTB4 zinc finger and BTB domain containing 4 -2.29096
HAPSTR1 HUWE1 associated protein modifying stress responses -2.23319
ERLIN1 ER lipid raft associated 1 -2.22324
AURKC aurora kinase C -2.21833
MYOM1 myomesin 1 -2.20332
SCGB2B2 secretoglobin, family 2B, member 2 -2.18755
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.15659
NRXN1 neurexin 1 -2.13895
TMTC1 transmembrane and tetratricopeptide repeat containing 1 -2.11934
HIBADH 3-hydroxyisobutyrate dehydrogenase -2.11537
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type -2.11216
DUSP19 dual specificity phosphatase 19 -2.11216
ECT2L epithelial cell transforming 2 like -2.11216
FAM229A family with sequence similarity 229, member A -2.11216
GEMIN6 gem (nuclear organelle) associated protein 6 -2.10787
DOK6 docking protein 6 -2.10787
MON1A MON1 secretory trafficking family member A -2.10787
SAAL1 serum amyloid A-like 1 -2.10424
LDLRAD4 low density lipoprotein receptor class A domain containing 4 -2.08987
FOXP1 forkhead box P1 -2.08985
MAP7 microtubule-associated protein 7 -2.08985
IRAK1BP1 interleukin-1 receptor-associated kinase 1 binding protein 1 -2.08091
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.06585
TSPAN18 tetraspanin 18 -2.04463
CMTM7 CKLF-like MARVEL transmembrane domain containing 7 -2.04244
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -2.02849
TMEM38A transmembrane protein 38A -2.01016
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 -2.00861
LSMEM2 leucine-rich single-pass membrane protein 2 -2.00068