MIER2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mesoderm induction early response 1, family member 2| (NCBI Entrez Gene Database, 54531)
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Genes

341 genes differentially expressed following the MIER2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NIBAN3 niban apoptosis regulator 3 3.93204
AHSG alpha-2-HS-glycoprotein 3.93204
NTN5 netrin 5 3.93204
ZNF750 zinc finger protein 750 3.93204
BMP8B bone morphogenetic protein 8b 3.93204
RAD21L1 RAD21-like 1 (S. pombe) 3.93204
SPEF1 sperm flagellar 1 3.93204
ADAM20 ADAM metallopeptidase domain 20 3.93204
SOST sclerostin 3.93204
TMPRSS12 transmembrane (C-terminal) protease, serine 12 3.93204
CLDN2 claudin 2 3.93204
TMIE transmembrane inner ear 3.93204
PRR22 proline rich 22 3.93204
ART1 ADP-ribosyltransferase 1 3.93204
OR52N2 olfactory receptor, family 52, subfamily N, member 2 3.93204
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 3.93204
GTSF1 gametocyte specific factor 1 3.93204
HLF hepatic leukemia factor 3.93204
SMIM31 small integral membrane protein 31 3.93204
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 3.93204
KRTAP5-11 keratin associated protein 5-11 3.93204
ADCY4 adenylate cyclase 4 3.93204
SSTR3 somatostatin receptor 3 3.92521
NFAM1 NFAT activating protein with ITAM motif 1 3.92521
FOXR1 forkhead box R1 3.92521
GJB1 gap junction protein, beta 1, 32kDa 3.92521
GJB3 gap junction protein, beta 3, 31kDa 3.92521
PAX6 paired box 6 3.92521
CXORF65 chromosome X open reading frame 65 3.92521
SSTR1 somatostatin receptor 1 3.92521
PCDHB4 protocadherin beta 4 3.92521
CTRC chymotrypsin C (caldecrin) 3.92521
MFAP5 microfibrillar associated protein 5 3.92521
TAL2 T-cell acute lymphocytic leukemia 2 3.92521
SPMIP10 sperm microtubule inner protein 10 3.92521
RNASE6 ribonuclease, RNase A family, k6 3.92521
TECTB tectorin beta 3.92521
EPHB3 EPH receptor B3 3.92521
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 3.92521
KIAA1755 KIAA1755 3.92521
FAM9B family with sequence similarity 9, member B 3.92521
TMEM132C transmembrane protein 132C 3.92521
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 3.92521
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 3.92521
SLC39A12 solute carrier family 39 (zinc transporter), member 12 3.92521
GATA4 GATA binding protein 4 3.92521
LCN15 lipocalin 15 3.92521
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 3.92521
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 3.92521
CXCL2 chemokine (C-X-C motif) ligand 2 3.92521
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 3.92521
OTUD6A OTU deubiquitinase 6A 3.92521
LYZL6 lysozyme-like 6 3.92521
SCGN secretagogin, EF-hand calcium binding protein 3.92521
FAM167B family with sequence similarity 167, member B 3.92521
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 3.92521
DLK2 delta-like 2 homolog (Drosophila) 3.92521
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.92521
PRDM7 PR domain containing 7 3.92521
ZNF705D zinc finger protein 705D 3.92521
LMNTD1 lamin tail domain containing 1 3.92521
SPIC Spi-C transcription factor (Spi-1/PU.1 related) 3.92521
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.92521
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 3.92521
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 3.92521
ANGPTL8 angiopoietin like 8 3.92521
DUSP29 dual specificity phosphatase 29 3.92521
TUBB8B tubulin beta 8B 3.92521
H4C14 H4 clustered histone 14 3.92521
MDFIC2 MyoD family inhibitor domain containing 2 3.92521
TEX50 testis expressed 50 3.92521
GPR83 G protein-coupled receptor 83 3.92521
FRK fyn-related Src family tyrosine kinase 3.92521
TARM1 T cell-interacting, activating receptor on myeloid cells 1 3.92521
MAP3K7CL MAP3K7 C-terminal like 3.92521
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 3.92521
PTTG2 pituitary tumor-transforming 2 3.92521
ATP13A4 ATPase type 13A4 3.92521
RAB44 RAB44, member RAS oncogene family 3.92521
OASL 2'-5'-oligoadenylate synthetase-like 3.92521
NXPE2 neurexophilin and PC-esterase domain family, member 2 3.92521
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 3.92521
ULBP1 UL16 binding protein 1 3.92521
DMBX1 diencephalon/mesencephalon homeobox 1 3.92521
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 3.92521
TBX3 T-box 3 3.92521
CREB3L3 cAMP responsive element binding protein 3-like 3 3.92521
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 3.92521
NPFF neuropeptide FF-amide peptide precursor 3.92521
GJD3 gap junction protein, delta 3, 31.9kDa 3.92521
SPATA31H1 SPATA31 subfamily H member 1 3.92521
CDC20B cell division cycle 20B 3.92521
TEX19 testis expressed 19 3.92521
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6 3.92521
PLA2G4E phospholipase A2, group IVE 3.92521
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 3.92521
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 3.92521
RAB40AL RAB40A, member RAS oncogene family-like 3.92521
PROK1 prokineticin 1 3.92521
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) 3.92521
FZD1 frizzled class receptor 1 3.92521
ALOX15B arachidonate 15-lipoxygenase, type B 3.92521
ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 3.92521
POU3F2 POU class 3 homeobox 2 3.92521
IFNL4 interferon, lambda 4 (gene/pseudogene) 3.92521
CPO carboxypeptidase O 3.92521
TTC9B tetratricopeptide repeat domain 9B 3.92521
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 3.92521
MBOAT4 membrane bound O-acyltransferase domain containing 4 3.92521
ARR3 arrestin 3, retinal (X-arrestin) 3.92521
CXCR4 chemokine (C-X-C motif) receptor 4 3.92521
PCP2 Purkinje cell protein 2 3.92521
SMIM22 small integral membrane protein 22 3.92521
C2ORF66 chromosome 2 open reading frame 66 3.92521
WFDC8 WAP four-disulfide core domain 8 3.92521
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.92521
FAM177B family with sequence similarity 177, member B 3.92521
APOC2 apolipoprotein C-II 3.92521
MAGEA11 melanoma antigen family A11 3.92521
EGR2 early growth response 2 3.92521
POTEF POTE ankyrin domain family, member F 3.92521
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 3.92521
ARHGAP40 Rho GTPase activating protein 40 3.92521
CLCNKB chloride channel, voltage-sensitive Kb 3.92521
DKK1 dickkopf WNT signaling pathway inhibitor 1 3.92521
CLEC18A C-type lectin domain family 18, member A 3.92521
SYT5 synaptotagmin V 3.92521
BTG4 B-cell translocation gene 4 3.92521
GOLGA8T golgin A8 family, member T 3.92521
NLRP9 NLR family, pyrin domain containing 9 3.92521
DKK2 dickkopf WNT signaling pathway inhibitor 2 3.92521
C5ORF46 chromosome 5 open reading frame 46 3.92521
ICAM2 intercellular adhesion molecule 2 3.92521
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.92521
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 3.92521
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 3.92521
R3HDML R3H domain containing-like 3.92521
SAMD9 sterile alpha motif domain containing 9 3.92521
TBX1 T-box 1 3.92521
LRRC74A leucine rich repeat containing 74A 3.92521
CD8A CD8a molecule 3.92521
ITGA10 integrin, alpha 10 3.92521
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3.92521
MT1A metallothionein 1A 3.92521
SDS serine dehydratase 3.92521
VTCN1 V-set domain containing T cell activation inhibitor 1 3.92521
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 3.92521
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 3.92521
PMP22 peripheral myelin protein 22 3.87744
ATP5MGL ATP synthase membrane subunit g like 3.87744
SLC16A13 solute carrier family 16, member 13 3.87021
DEUP1 deuterosome assembly protein 1 3.53036
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 3.40946
CBLIF cobalamin binding intrinsic factor 3.10977
PTPN20 protein tyrosine phosphatase, non-receptor type 20 3.10977
AGK acylglycerol kinase 3.01378
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 2.99804
CNTD1 cyclin N-terminal domain containing 1 2.99391
PGLYRP1 peptidoglycan recognition protein 1 2.99391
AZU1 azurocidin 1 2.99391
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 2.99391
ISG15 ISG15 ubiquitin-like modifier 2.91065
TERF2IP telomeric repeat binding factor 2, interacting protein 2.83655
PI4K2B phosphatidylinositol 4-kinase type 2 beta 2.83469
USP25 ubiquitin specific peptidase 25 2.76034
PLIN2 perilipin 2 2.68523
RAD51 RAD51 recombinase 2.68375
ENGASE endo-beta-N-acetylglucosaminidase 2.63797
DPP10 dipeptidyl-peptidase 10 (non-functional) 2.58613
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 2.54721
LCN2 lipocalin 2 2.54721
EIF3A eukaryotic translation initiation factor 3, subunit A 2.54721
HSH2D hematopoietic SH2 domain containing 2.54721
TJP2 tight junction protein 2 2.52797
HSPG2 heparan sulfate proteoglycan 2 2.52797
IARS1 isoleucyl-tRNA synthetase 1 2.52797
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 2.51949
BTN3A3 butyrophilin, subfamily 3, member A3 2.47768
ITPRID2 ITPR interacting domain containing 2 2.47393
TOP2B topoisomerase (DNA) II beta 180kDa 2.45706
CHPT1 choline phosphotransferase 1 2.39969
CFAP69 cilia and flagella associated protein 69 2.39504
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 2.39086
KIFBP kinesin family binding protein 2.38221
AFAP1 actin filament associated protein 1 2.37998
PGBD1 piggyBac transposable element derived 1 2.36518
PRPF4B pre-mRNA processing factor 4B 2.35645
FAN1 FANCD2/FANCI-associated nuclease 1 2.3505
GCC2 GRIP and coiled-coil domain containing 2 2.33206
GLRA3 glycine receptor, alpha 3 2.31178
FRS2 fibroblast growth factor receptor substrate 2 2.29226
SOBP sine oculis binding protein homolog (Drosophila) 2.289
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 2.28298
ANXA4 annexin A4 2.27719
NAT10 N-acetyltransferase 10 (GCN5-related) 2.27147
CXXC1 CXXC finger protein 1 2.25256
DNAAF10 dynein axonemal assembly factor 10 2.24584
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 2.1815
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 2.17155
LIN54 lin-54 DREAM MuvB core complex component 2.15416
KIF7 kinesin family member 7 2.14902
SLC6A16 solute carrier family 6, member 16 2.14714
SPINDOC spindlin interactor and repressor of chromatin binding 2.14698
SARS1 seryl-tRNA synthetase 1 2.13617
CCDC88A coiled-coil domain containing 88A 2.13586
PUDP pseudouridine 5'-phosphatase 2.11905
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.08722
SNCAIP synuclein, alpha interacting protein 2.05917
MIB2 mindbomb E3 ubiquitin protein ligase 2 2.03658
RNF217 ring finger protein 217 2.01332
DIRAS1 DIRAS family, GTP-binding RAS-like 1 2.01332
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.0116
SHARPIN SHANK-associated RH domain interactor 2.0116
TRIM35 tripartite motif containing 35 2.0116

decreased expression

Symbol Name Standardized Value
GPRASP1 G protein-coupled receptor associated sorting protein 1 -3.93204
FCRL5 Fc receptor-like 5 -3.92521
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -3.92521
ANKRD7 ankyrin repeat domain 7 -3.92521
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -3.92521
ACP5 acid phosphatase 5, tartrate resistant -3.92521
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 -3.92521
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled -3.80476
PXT1 peroxisomal, testis specific 1 -3.80476
DNASE1L2 deoxyribonuclease I-like 2 -3.80476
PRSS53 protease, serine, 53 -3.80476
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B -3.80476
LURAP1L leucine rich adaptor protein 1-like -3.80476
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -3.80476
USP50 ubiquitin specific peptidase 50 -3.80476
GPRC5A G protein-coupled receptor, class C, group 5, member A -3.80476
IRX1 iroquois homeobox 1 -3.80476
S100A2 S100 calcium binding protein A2 -3.80476
BMP5 bone morphogenetic protein 5 -3.80476
RPL3L ribosomal protein L3-like -3.80476
MAGED4 melanoma antigen family D4 -3.80476
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -3.80476
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E -3.80476
ALPK2 alpha-kinase 2 -3.80476
APOA1 apolipoprotein A-I -3.80476
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -3.80476
CLIC5 chloride intracellular channel 5 -3.80476
MYOT myotilin -3.80476
AMH anti-Mullerian hormone -3.80476
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -3.80476
GATA5 GATA binding protein 5 -3.80476
DDTL D-dopachrome tautomerase-like -3.80476
CNGB3 cyclic nucleotide gated channel beta 3 -3.80476
TRIM55 tripartite motif containing 55 -3.80476
RUNX3 runt-related transcription factor 3 -3.80476
LEF1 lymphoid enhancer-binding factor 1 -3.80476
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) -3.80476
GOLGA6L4 golgin A6 family-like 4 -3.80476
DRC5 dynein regulatory complex subunit 5 -3.80476
FNDC8 fibronectin type III domain containing 8 -3.80476
OLFML1 olfactomedin-like 1 -3.80476
GSTM2 glutathione S-transferase mu 2 (muscle) -3.80476
TEX101 testis expressed 101 -3.80476
PCDHB14 protocadherin beta 14 -3.80476
PYY peptide YY -3.69479
MPZL2 myelin protein zero-like 2 -3.69479
GAB3 GRB2-associated binding protein 3 -3.69479
EAPP E2F-associated phosphoprotein -3.36016
ARMCX3 armadillo repeat containing, X-linked 3 -3.28454
CCDC127 coiled-coil domain containing 127 -3.17491
BEND5 BEN domain containing 5 -2.99335
TMC1 transmembrane channel-like 1 -2.94109
PCLAF PCNA clamp associated factor -2.87996
AKAP10 A kinase (PRKA) anchor protein 10 -2.83655
INTS3 integrator complex subunit 3 -2.76952
METRN meteorin, glial cell differentiation regulator -2.74132
CFAP210 cilia and flagella associated protein 210 -2.69206
CUL5 cullin 5 -2.69041
USP21 ubiquitin specific peptidase 21 -2.63797
PSD pleckstrin and Sec7 domain containing -2.6269
TLE2 transducin-like enhancer of split 2 -2.6269
AVPI1 arginine vasopressin-induced 1 -2.57809
KIAA2012 KIAA2012 -2.56844
DNAH12 dynein, axonemal, heavy chain 12 -2.56844
BARX1 BARX homeobox 1 -2.56844
DCLK3 doublecortin-like kinase 3 -2.56844
TNS1-AS1 TNS1 antisense RNA 1 -2.56844
DNAAF19 dynein axonemal assembly factor 19 -2.56844
SHISAL2A shisa like 2A -2.56844
DRC3 dynein regulatory complex subunit 3 -2.56844
PTN pleiotrophin -2.53127
MIER2 mesoderm induction early response 1, family member 2 -2.52797
TRAPPC9 trafficking protein particle complex 9 -2.48063
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa -2.47864
DRG1 developmentally regulated GTP binding protein 1 -2.42611
BRAT1 BRCA1-associated ATM activator 1 -2.39522
CBX3 chromobox homolog 3 -2.39086
LTBP3 latent transforming growth factor beta binding protein 3 -2.38221
LRRC17 leucine rich repeat containing 17 -2.38186
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.36662
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.3505
FAM78A family with sequence similarity 78, member A -2.33263
EXTL3 exostosin-like glycosyltransferase 3 -2.33031
TRAK1 trafficking protein, kinesin binding 1 -2.31608
RHBG Rh family, B glycoprotein (gene/pseudogene) -2.31492
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -2.31492
CLDN3 claudin 3 -2.29226
DNAH1 dynein, axonemal, heavy chain 1 -2.289
ULBP3 UL16 binding protein 3 -2.289
VENTX VENT homeobox -2.289
KANK4 KN motif and ankyrin repeat domains 4 -2.289
BASP1 brain abundant, membrane attached signal protein 1 -2.28402
UQCRC1 ubiquinol-cytochrome c reductase core protein I -2.25837
FBXO9 F-box protein 9 -2.25743
MFSD11 major facilitator superfamily domain containing 11 -2.25743
SH3PXD2A SH3 and PX domains 2A -2.24452
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 -2.24141
ZNF717 zinc finger protein 717 -2.22325
FAM110D family with sequence similarity 110, member D -2.20059
ADPRH ADP-ribosylarginine hydrolase -2.20059
DCBLD2 discoidin, CUB and LCCL domain containing 2 -2.20059
OXTR oxytocin receptor -2.20059
KIRREL2 kin of IRRE like 2 (Drosophila) -2.20059
PTCH1 patched 1 -2.19015
CLEC16A C-type lectin domain family 16, member A -2.18728
PCDHA5 protocadherin alpha 5 -2.18728
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A -2.18728
SLITRK4 SLIT and NTRK-like family, member 4 -2.18728
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 -2.18728
MOB3C MOB kinase activator 3C -2.18728
SELENOV selenoprotein V -2.18246
BBS7 Bardet-Biedl syndrome 7 -2.17155
MLXIPL MLX interacting protein-like -2.16529
ZZZ3 zinc finger, ZZ-type containing 3 -2.15961
ISOC2 isochorismatase domain containing 2 -2.15961
DCLRE1C DNA cross-link repair 1C -2.15919
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -2.15053
TMEM255B transmembrane protein 255B -2.14714
H1-2 H1.2 linker histone, cluster member -2.14714
ERI2 ERI1 exoribonuclease family member 2 -2.09843
WASL Wiskott-Aldrich syndrome-like -2.09109
RNPC3 RNA-binding region (RNP1, RRM) containing 3 -2.04618
ACSL1 acyl-CoA synthetase long-chain family member 1 -2.04168
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -2.01368
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.0116
LCMT1 leucine carboxyl methyltransferase 1 -2.0116
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.00688