MITF Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description microphthalmia-associated transcription factor|This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4286)
External Link https://ncbi.nlm.nih.gov/gene/4286
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Genes

499 genes differentially expressed following the MITF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CDC20 cell division cycle 20 0.0146816
LTF lactotransferrin 0.0143085
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0142854
NTS neurotensin 0.0137472
FGFR3 fibroblast growth factor receptor 3 0.0133591
DCXR dicarbonyl/L-xylulose reductase 0.0130178
HBB hemoglobin, beta 0.0120562
CD40 CD40 molecule, TNF receptor superfamily member 5 0.011754
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.011683
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0113155
S100A9 S100 calcium binding protein A9 0.0110623
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.0108775
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.0106879
S100A8 S100 calcium binding protein A8 0.0102483
BIRC5 baculoviral IAP repeat containing 5 0.0102034
CETN2 centrin, EF-hand protein, 2 0.00995293
CCNA2 cyclin A2 0.00994179
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00985388
CDCA4 cell division cycle associated 4 0.00974315
NEK2 NIMA-related kinase 2 0.00943162
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0093676
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00932428
RNF167 ring finger protein 167 0.00929658
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.0092892
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00925731
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00912106
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00903165
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00875509
GCA grancalcin, EF-hand calcium binding protein 0.00873448
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00872961
ACP3 acid phosphatase 3 0.00863376
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00862592
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 0.00862395
SRGN serglycin 0.0086139
NMU neuromedin U 0.00855402
TMEM14B transmembrane protein 14B 0.00851572
PUF60 poly-U binding splicing factor 60KDa 0.00847031
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00830532
KRT15 keratin 15, type I 0.00826084
OLFM4 olfactomedin 4 0.00825244
CD38 CD38 molecule 0.00825008
CST7 cystatin F (leukocystatin) 0.00823263
PRF1 perforin 1 (pore forming protein) 0.0082172
DCK deoxycytidine kinase 0.00820287
RPA3 replication protein A3, 14kDa 0.00818435
VBP1 von Hippel-Lindau binding protein 1 0.00818134
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00813316
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.00812225
PGD phosphogluconate dehydrogenase 0.00812078
INSIG1 insulin induced gene 1 0.00809034
IDO1 indoleamine 2,3-dioxygenase 1 0.00802679
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00796535
TXNDC9 thioredoxin domain containing 9 0.00796126
AKAP7 A kinase (PRKA) anchor protein 7 0.007961
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00792164
GLOD4 glyoxalase domain containing 4 0.00791467
ANPEP alanyl (membrane) aminopeptidase 0.00791258
HPF1 histone PARylation factor 1 0.00787944
MT1G metallothionein 1G 0.00787442
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00786666
CA12 carbonic anhydrase XII 0.0077924
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00772049
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00770113
DAD1 defender against cell death 1 0.0076973
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00766802
PCGF2 polycomb group ring finger 2 0.00763063
NUP37 nucleoporin 37kDa 0.00762392
ECI2 enoyl-CoA delta isomerase 2 0.00760695
GEMIN2 gem (nuclear organelle) associated protein 2 0.00758787
KIF20A kinesin family member 20A 0.00758551
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00758343
EAPP E2F-associated phosphoprotein 0.00756086
ASF1A anti-silencing function 1A histone chaperone 0.00753315
RPS5 ribosomal protein S5 0.00749473
C1QBP complement component 1, q subcomponent binding protein 0.00746355
PIMREG PICALM interacting mitotic regulator 0.00745236
DHCR24 24-dehydrocholesterol reductase 0.00744132
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00742539
COMMD8 COMM domain containing 8 0.00741058
LBR lamin B receptor 0.00736611
AMD1 adenosylmethionine decarboxylase 1 0.00735982
WDR61 WD repeat domain 61 0.00735445
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00733027
HMGB2 high mobility group box 2 0.00730761
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.00728908
SLC2A4RG SLC2A4 regulator 0.00728287
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.00728132
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00727631
LGALS13 lectin, galactoside-binding, soluble, 13 0.00723767
CD8A CD8a molecule 0.00723289
CD320 CD320 molecule 0.00721164
HOXB7 homeobox B7 0.00719458
PTTG1 pituitary tumor-transforming 1 0.00717103
C3ORF14 chromosome 3 open reading frame 14 0.00716995
HLA-DOB major histocompatibility complex, class II, DO beta 0.00716538
C1ORF115 chromosome 1 open reading frame 115 0.00715217
TRMT5 tRNA methyltransferase 5 0.00709255
DHCR7 7-dehydrocholesterol reductase 0.00706552
S100A12 S100 calcium binding protein A12 0.00706228
ABHD10 abhydrolase domain containing 10 0.00705293
GPI glucose-6-phosphate isomerase 0.00704216
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00703386
CENPX centromere protein X 0.00701644
ENO2 enolase 2 (gamma, neuronal) 0.00701114
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00699913
ADAMDEC1 ADAM-like, decysin 1 0.0069785
THYN1 thymocyte nuclear protein 1 0.00696391
SPC25 SPC25, NDC80 kinetochore complex component 0.00694005
OIP5 Opa interacting protein 5 0.00692437
ELOVL6 ELOVL fatty acid elongase 6 0.00691882
LAGE3 L antigen family, member 3 0.00691384
CDT1 chromatin licensing and DNA replication factor 1 0.00691328
C12ORF29 chromosome 12 open reading frame 29 0.00691194
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00688858
BMX BMX non-receptor tyrosine kinase 0.00688588
RTN1 reticulon 1 0.00688027
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00687805
PPA2 pyrophosphatase (inorganic) 2 0.00687316
ASF1B anti-silencing function 1B histone chaperone 0.00682741
CCNB2 cyclin B2 0.00681936
GPR171 G protein-coupled receptor 171 0.00681924
CD96 CD96 molecule 0.00681851
CHEK2 checkpoint kinase 2 0.00681144
JCHAIN joining chain of multimeric IgA and IgM 0.00680671
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00680174
RNASEH2A ribonuclease H2, subunit A 0.00678137
KIF15 kinesin family member 15 0.00677082
HOXB2 homeobox B2 0.00673521
B3GNT1 0.00670862
FASN fatty acid synthase 0.00670763
FOXG1 forkhead box G1 0.00669907
DNASE1L3 deoxyribonuclease I-like 3 0.00669375
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.00665653
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.00665443
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00663284
SFRP1 secreted frizzled-related protein 1 0.00659196
LIG1 ligase I, DNA, ATP-dependent 0.00657623
CD48 CD48 molecule 0.00657203
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00653298
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00653274
CCNF cyclin F 0.00653158
PIR pirin (iron-binding nuclear protein) 0.0065137
COPS4 COP9 signalosome subunit 4 0.00648798
FBL fibrillarin 0.0064607
CSTA cystatin A (stefin A) 0.00645342
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 0.00642821
HAUS4 HAUS augmin-like complex, subunit 4 0.00642052
XCL1 chemokine (C motif) ligand 1 0.00641183
MSMO1 methylsterol monooxygenase 1 0.00641079
RNASE6 ribonuclease, RNase A family, k6 0.00639697
LMNB1 lamin B1 0.00639551
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00638487
ARL3 ADP-ribosylation factor-like 3 0.00638474
TECR trans-2,3-enoyl-CoA reductase 0.00638377
LTA4H leukotriene A4 hydrolase 0.00638122
SDC1 syndecan 1 0.00637128
GPM6A glycoprotein M6A 0.00636957
RAB13 RAB13, member RAS oncogene family 0.00636912
ELANE elastase, neutrophil expressed 0.00636808
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00634808
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00634157
NSL1 NSL1, MIS12 kinetochore complex component 0.00633683
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.00633303
GPM6B glycoprotein M6B 0.0063318
IL18RAP interleukin 18 receptor accessory protein 0.0063288
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00632065
HBD hemoglobin, delta 0.00627845
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 0.00627738
KIF4A kinesin family member 4A 0.00626977
GANAB glucosidase, alpha; neutral AB 0.00626876
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00625849
CXCL12 chemokine (C-X-C motif) ligand 12 0.00625602
VDAC3 voltage-dependent anion channel 3 0.00624614
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.00623347
FBXO5 F-box protein 5 0.00623195
NT5DC2 5'-nucleotidase domain containing 2 0.00623094
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 0.00623077
GNLY granulysin 0.00621696
ANO10 anoctamin 10 0.00620273
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.00620118
PLBD1 phospholipase B domain containing 1 0.00618588
ACAT2 acetyl-CoA acetyltransferase 2 0.00618083
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00616899
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00614937
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00614834
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.00614648
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00614589
SELENBP1 selenium binding protein 1 0.00613993
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00612638
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00611842
TPX2 TPX2, microtubule-associated 0.00611041
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00610856
FRG1 FSHD region gene 1 0.00609497
FOXM1 forkhead box M1 0.00607562
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.0060673
GIMAP5 GTPase, IMAP family member 5 0.00606029
BLVRB biliverdin reductase B 0.00605868
CDK1 cyclin-dependent kinase 1 0.00605527
TARP TCR gamma alternate reading frame protein 0.00604656
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.00603576
CD2 CD2 molecule 0.00603214
PBX1 pre-B-cell leukemia homeobox 1 0.00600321
CRYL1 crystallin, lambda 1 0.00600244
TTK TTK protein kinase 0.00600005
MCM6 minichromosome maintenance complex component 6 0.00599962
GPR18 G protein-coupled receptor 18 0.00599954
NCAPH non-SMC condensin I complex, subunit H 0.00599829
MT1F metallothionein 1F 0.00598571
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00597991
NKG7 natural killer cell granule protein 7 0.00597026
SV2A synaptic vesicle glycoprotein 2A 0.00595486
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00594145
ZNF226 zinc finger protein 226 0.00593317
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.00593307
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00592069
IQCG IQ motif containing G 0.00591648
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.00590607
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 0.00590252
MMRN1 multimerin 1 0.00588399
IL2RB interleukin 2 receptor, beta 0.00588033
ATRAID all-trans retinoic acid-induced differentiation factor 0.00587603
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.00587587
CLEC10A C-type lectin domain family 10, member A 0.00586972
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00586941
RPRD1A regulation of nuclear pre-mRNA domain containing 1A 0.0058692
CRIP2 cysteine-rich protein 2 0.00585823
TMEM38B transmembrane protein 38B 0.00584173
GIMAP4 GTPase, IMAP family member 4 0.00583128
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00582956
ESD esterase D 0.00582676
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.00581737
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.0058138
FLOT2 flotillin 2 0.00580973
AHSP alpha hemoglobin stabilizing protein 0.00579325
GLB1 galactosidase, beta 1 0.00578937
CCR7 chemokine (C-C motif) receptor 7 0.00578871
ALDOC aldolase C, fructose-bisphosphate 0.00578701
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.00578325
USP1 ubiquitin specific peptidase 1 0.00576802
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00576424
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00575018
EAF2 ELL associated factor 2 0.00574651
FXYD3 FXYD domain containing ion transport regulator 3 0.00573734
KIF18A kinesin family member 18A 0.0057328
DEPDC1 DEP domain containing 1 0.00572688
PGAP3 post-GPI attachment to proteins 3 0.00571236
EMC9 ER membrane protein complex subunit 9 0.00569967
CXCL6 chemokine (C-X-C motif) ligand 6 0.00568043
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00567781
CENPF centromere protein F, 350/400kDa 0.00566629

decreased expression

Symbol Name Standardized Value
IFI6 interferon, alpha-inducible protein 6 -0.0184225
IFI27 interferon, alpha-inducible protein 27 -0.0173398
ISG15 ISG15 ubiquitin-like modifier -0.0160414
MX1 MX dynamin-like GTPase 1 -0.0144109
TENT5A terminal nucleotidyltransferase 5A -0.0143276
ASPN asporin -0.0140315
MIR22HG MIR22 host gene -0.0130458
HSPA1A heat shock 70kDa protein 1A -0.0127824
THBS1 thrombospondin 1 -0.0126722
HMOX1 heme oxygenase 1 -0.0126552
PLK2 polo-like kinase 2 -0.0124007
SFRP4 secreted frizzled-related protein 4 -0.0123812
RTN2 reticulon 2 -0.0121993
HSPB8 heat shock 22kDa protein 8 -0.0119112
POSTN periostin, osteoblast specific factor -0.0118966
IRF7 interferon regulatory factor 7 -0.0117262
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0117004
TIMP3 TIMP metallopeptidase inhibitor 3 -0.0115754
FN1 fibronectin 1 -0.0114435
COL15A1 collagen, type XV, alpha 1 -0.0113295
ASS1 argininosuccinate synthase 1 -0.0111825
PIEZO2 piezo-type mechanosensitive ion channel component 2 -0.0110148
TAGLN transgelin -0.0108924
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0106611
CADM1 cell adhesion molecule 1 -0.0106144
INHBA inhibin, beta A -0.0105712
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0104801
IFI44L interferon-induced protein 44-like -0.0104537
GOLGA8A golgin A8 family, member A -0.0104215
HIST1H2BD histone cluster 1, H2bd -0.0103452
AHR aryl hydrocarbon receptor -0.0102904
THBS4 thrombospondin 4 -0.0102739
XAF1 XIAP associated factor 1 -0.010223
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0102096
DYNLL1 dynein, light chain, LC8-type 1 -0.0101283
RGS5 regulator of G-protein signaling 5 -0.0100985
ZNF91 zinc finger protein 91 -0.0100273
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0100158
CD163 CD163 molecule -0.00998214
BST2 bone marrow stromal cell antigen 2 -0.00995884
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0099263
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00991231
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00986036
TRIM22 tripartite motif containing 22 -0.00985057
DUSP5 dual specificity phosphatase 5 -0.00976924
MFAP5 microfibrillar associated protein 5 -0.00974591
SIK1 salt-inducible kinase 1 -0.00974289
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00973568
FHL2 four and a half LIM domains 2 -0.00971217
KLF6 Kruppel-like factor 6 -0.00963508
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00941788
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00939635
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.0093601
TFPI2 tissue factor pathway inhibitor 2 -0.00932841
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00929205
NOTCH2NL notch 2 N-terminal like -0.00924335
ZMAT3 zinc finger, matrin-type 3 -0.00922248
CD14 CD14 molecule -0.00922096
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.0091857
NRCAM neuronal cell adhesion molecule -0.00916794
AREG amphiregulin -0.00916327
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00910914
COL10A1 collagen, type X, alpha 1 -0.00909148
RUNX1 runt-related transcription factor 1 -0.00908433
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00907907
CUX1 cut-like homeobox 1 -0.00907687
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00903756
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00901057
PRSS23 protease, serine, 23 -0.00900409
SNAI2 snail family zinc finger 2 -0.00888088
ATF3 activating transcription factor 3 -0.00875674
COMP cartilage oligomeric matrix protein -0.00873448
TNNC1 troponin C type 1 (slow) -0.00873058
HIST1H2BK histone cluster 1, H2bk -0.00869821
DAPK1 death-associated protein kinase 1 -0.0086844
MVP major vault protein -0.00867632
MXRA5 matrix-remodelling associated 5 -0.00852944
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00850164
EDNRA endothelin receptor type A -0.00850105
CYTH1 cytohesin 1 -0.00843571
CKM creatine kinase, muscle -0.00842905
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.00837588
IER5 immediate early response 5 -0.00837296
KLHL41 kelch-like family member 41 -0.00834407
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00833386
INSR insulin receptor -0.00832899
PTK2 protein tyrosine kinase 2 -0.00827898
JMJD6 jumonji domain containing 6 -0.00827153
OLFML2B olfactomedin-like 2B -0.00823215
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00822288
IL6 interleukin 6 -0.00820923
EMP1 epithelial membrane protein 1 -0.00820634
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00818702
IFI44 interferon-induced protein 44 -0.00813934
HBEGF heparin-binding EGF-like growth factor -0.00809366
PDE4DIP phosphodiesterase 4D interacting protein -0.00803764
LIMCH1 LIM and calponin homology domains 1 -0.0079906
TXLNA taxilin alpha -0.00798939
CST1 cystatin SN -0.00797835
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00797201
PLAAT3 phospholipase A and acyltransferase 3 -0.00796407
CD93 CD93 molecule -0.00794822
OLFML2A olfactomedin-like 2A -0.00792203
MEIS1 Meis homeobox 1 -0.00791099
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00789342
TUFT1 tuftelin 1 -0.00785824
FILIP1L filamin A interacting protein 1-like -0.00784508
SGK1 serum/glucocorticoid regulated kinase 1 -0.00781853
TIGAR TP53 induced glycolysis regulatory phosphatase -0.007813
WASL Wiskott-Aldrich syndrome-like -0.0077679
CTSA cathepsin A -0.00775668
SOX4 SRY (sex determining region Y)-box 4 -0.00772546
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00771361
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00770076
COL16A1 collagen, type XVI, alpha 1 -0.00768652
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00767475
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00764969
BIK BCL2-interacting killer (apoptosis-inducing) -0.00763299
FOSB FBJ murine osteosarcoma viral oncogene homolog B -0.00762892
SLC38A1 solute carrier family 38, member 1 -0.00760583
MN1 meningioma (disrupted in balanced translocation) 1 -0.00760431
ZNF160 zinc finger protein 160 -0.00754822
ADCY9 adenylate cyclase 9 -0.00754795
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00753753
TTN titin -0.00753204
CEL carboxyl ester lipase -0.00752731
RHOBTB3 Rho-related BTB domain containing 3 -0.00750311
JUNB jun B proto-oncogene -0.00748281
NUAK1 NUAK family, SNF1-like kinase, 1 -0.00745918
TNNC2 troponin C type 2 (fast) -0.00744573
EGR1 early growth response 1 -0.00744369
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00742562
ACTA1 actin, alpha 1, skeletal muscle -0.0074241
TNNT1 troponin T type 1 (skeletal, slow) -0.00741227
GAS6 growth arrest-specific 6 -0.00740797
DOCK9 dedicator of cytokinesis 9 -0.0073982
FNDC3B fibronectin type III domain containing 3B -0.00737964
IL6R interleukin 6 receptor -0.00737188
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00736231
LAMA3 laminin, alpha 3 -0.00736152
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.00734083
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -0.00733165
WSB1 WD repeat and SOCS box containing 1 -0.00729157
COL14A1 collagen, type XIV, alpha 1 -0.00728788
IGF2R insulin-like growth factor 2 receptor -0.00725199
EGFL6 EGF-like-domain, multiple 6 -0.00723031
LAMB3 laminin, beta 3 -0.00721994
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00721929
THBS2 thrombospondin 2 -0.00719964
DUSP4 dual specificity phosphatase 4 -0.00719732
PDGFD platelet derived growth factor D -0.00718282
BEX4 brain expressed, X-linked 4 -0.00718128
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00717509
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.00717293
TNNI2 troponin I type 2 (skeletal, fast) -0.00714882
HIST1H2AC histone cluster 1, H2ac -0.00713832
IRS2 insulin receptor substrate 2 -0.00713724
AKAP12 A kinase (PRKA) anchor protein 12 -0.00713029
PODXL podocalyxin-like -0.00712445
FBLN2 fibulin 2 -0.00710625
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00710505
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00709252
REXO2 RNA exonuclease 2 -0.00708339
BTG2 BTG family, member 2 -0.00707686
IRF9 interferon regulatory factor 9 -0.00706518
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00706278
PLXDC1 plexin domain containing 1 -0.007059
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00704922
PDGFRL platelet-derived growth factor receptor-like -0.00703937
CRYAB crystallin, alpha B -0.0070139
STAT1 signal transducer and activator of transcription 1, 91kDa -0.00698894
CCN2 cellular communication network factor 2 -0.00696997
MYOF myoferlin -0.00695139
PEG3 paternally expressed 3 -0.00695091
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00695071
JAK1 Janus kinase 1 -0.00692258
RFTN1 raftlin, lipid raft linker 1 -0.00690498
GOLGA8H golgin A8 family, member H -0.00689571
PLK3 polo-like kinase 3 -0.0068828
COL11A1 collagen, type XI, alpha 1 -0.00686469
COG7 component of oligomeric golgi complex 7 -0.00686116
NCOA3 nuclear receptor coactivator 3 -0.00684528
MB myoglobin -0.00683834
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00682406
MTUS1 microtubule associated tumor suppressor 1 -0.00681055
SLC16A6 solute carrier family 16, member 6 -0.0067954
IGFBP6 insulin-like growth factor binding protein 6 -0.00677439
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00674018
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00673846
EPHA2 EPH receptor A2 -0.00673564
F13A1 coagulation factor XIII, A1 polypeptide -0.00673284
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00672623
ADGRF5 adhesion G protein-coupled receptor F5 -0.00672352
MATN2 matrilin 2 -0.00669291
TRIO trio Rho guanine nucleotide exchange factor -0.0066673
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -0.00666372
ARHGAP29 Rho GTPase activating protein 29 -0.00665856
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00665222
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00665209
IRS1 insulin receptor substrate 1 -0.00664984
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00664788
PEG10 paternally expressed 10 -0.00664742
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00664539
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00663121
CFB complement factor B -0.00661098
SUSD6 sushi domain containing 6 -0.00660322
CCND1 cyclin D1 -0.0066015
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00659474
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00659157
KRT23 keratin 23, type I -0.0065758
AKAP8 A kinase (PRKA) anchor protein 8 -0.00657397
GAB2 GRB2-associated binding protein 2 -0.00657269
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00656165
MAP7 microtubule-associated protein 7 -0.00656066
PKP2 plakophilin 2 -0.0065387
TSPAN8 tetraspanin 8 -0.00650993
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00650533
DUSP1 dual specificity phosphatase 1 -0.00650199
TNS3 tensin 3 -0.00650135
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -0.00648656
PCDH17 protocadherin 17 -0.00647738
SYT1 synaptotagmin I -0.00645076
PDLIM3 PDZ and LIM domain 3 -0.00644192
DDA1 DET1 and DDB1 associated 1 -0.00643741
LIF leukemia inhibitory factor -0.0064312
NPEPL1 aminopeptidase-like 1 -0.00642846
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.00642234
CDV3 CDV3 homolog (mouse) -0.00641309
KLC1 kinesin light chain 1 -0.006406
CARD10 caspase recruitment domain family, member 10 -0.00639973
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00637287
ADAM10 ADAM metallopeptidase domain 10 -0.00636203
SPATA20 spermatogenesis associated 20 -0.00635075
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -0.00633657
RBM47 RNA binding motif protein 47 -0.00631675
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00631053
KMT5B lysine methyltransferase 5B -0.00630853
MEG3 maternally expressed 3 (non-protein coding) -0.00629757
L1CAM L1 cell adhesion molecule -0.00629043
GLA galactosidase, alpha -0.00628778
AMOTL2 angiomotin like 2 -0.00628018
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.0062797
MCM2 minichromosome maintenance complex component 2 -0.00626891
SENP6 SUMO1/sentrin specific peptidase 6 -0.00626318
SNAP25 synaptosomal-associated protein, 25kDa -0.00625978
PTK2B protein tyrosine kinase 2 beta -0.00625547
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00624637
NPC1 Niemann-Pick disease, type C1 -0.00624461
STX16 syntaxin 16 -0.00624285