MIX23 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description mitochondrial matrix import factor 23 (NCBI Entrez Gene Database, 131076)
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Genes

331 genes differentially expressed following the MIX23 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GOLGA6B golgin A6 family, member B 2.72187
LDB3 LIM domain binding 3 2.72187
ARSI arylsulfatase family, member I 2.72187
NTN5 netrin 5 2.72187
CLEC4G C-type lectin domain family 4, member G 2.72187
CFAP61 cilia and flagella associated protein 61 2.72187
C20ORF144 chromosome 20 open reading frame 144 2.72187
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.72187
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.72187
BTN1A1 butyrophilin, subfamily 1, member A1 2.72187
WFDC10A WAP four-disulfide core domain 10A 2.72187
GALR3 galanin receptor 3 2.72187
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 2.72187
SPINK6 serine peptidase inhibitor, Kazal type 6 2.72187
PSG8 pregnancy specific beta-1-glycoprotein 8 2.72187
EPHB3 EPH receptor B3 2.72187
THPO thrombopoietin 2.72187
ARHGAP40 Rho GTPase activating protein 40 2.72187
SLC22A10 solute carrier family 22, member 10 2.72187
NES nestin 2.72187
OVCH1 ovochymase 1 2.72187
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 2.72187
TTLL13 tubulin tyrosine ligase like 13 2.72187
ASGR2 asialoglycoprotein receptor 2 2.72187
HAS1 hyaluronan synthase 1 2.72187
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 2.66186
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.66186
SCN2B sodium channel, voltage gated, type II beta subunit 2.66186
DUXA double homeobox A 2.66186
FGF23 fibroblast growth factor 23 2.66186
CEMP1 cementum protein 1 2.66186
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.66186
LRRD1 leucine-rich repeats and death domain containing 1 2.66186
CDH5 cadherin 5, type 2 (vascular endothelium) 2.66186
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 2.66186
SCG2 secretogranin II 2.66186
MYO7B myosin VIIB 2.66186
SLC26A9 solute carrier family 26 (anion exchanger), member 9 2.66186
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 2.66186
MILR1 mast cell immunoglobulin-like receptor 1 2.66186
CAPS calcyphosine 2.66186
ACOT12 acyl-CoA thioesterase 12 2.66186
DPPA3 developmental pluripotency associated 3 2.66186
MEIKIN meiotic kinetochore factor 2.66186
CPB2 carboxypeptidase B2 (plasma) 2.66186
MS4A18 membrane-spanning 4-domains, subfamily A, member 18 2.66186
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 2.66186
ALPK2 alpha-kinase 2 2.66186
ASPA aspartoacylase 2.66186
RSPO3 R-spondin 3 2.66186
MSC musculin 2.66186
SIGLEC6 sialic acid binding Ig-like lectin 6 2.66186
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 2.66186
GJB4 gap junction protein, beta 4, 30.3kDa 2.66186
GSTM5 glutathione S-transferase mu 5 2.66186
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.66186
PLXNB3 plexin B3 2.66186
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.66186
HNF4A hepatocyte nuclear factor 4, alpha 2.66186
SPMIP1 sperm microtubule inner protein 1 2.66186
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2.66186
ELOVL3 ELOVL fatty acid elongase 3 2.66186
OR2T8 olfactory receptor, family 2, subfamily T, member 8 2.66186
FOXN4 forkhead box N4 2.66186
PDF peptide deformylase (mitochondrial) 2.66186
GIPR gastric inhibitory polypeptide receptor 2.66186
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 2.66186
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 2.66186
TFF1 trefoil factor 1 2.66186
PTH1R parathyroid hormone 1 receptor 2.66186
DEPP1 DEPP autophagy regulator 1 2.66186
SPMIP9 sperm microtubule inner protein 9 2.66186
SPATA31H1 SPATA31 subfamily H member 1 2.66186
H4C14 H4 clustered histone 14 2.66186
ARMH2 armadillo like helical domain containing 2 2.66186
CFAP299 cilia and flagella associated protein 299 2.66186
CATSPERZ catsper channel auxiliary subunit zeta 2.66186
GARIN1A golgi associated RAB2 interactor 1A 2.66186
CCN5 cellular communication network factor 5 2.66186
VEGFD vascular endothelial growth factor D 2.66186
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 2.66186
DOK2 docking protein 2, 56kDa 2.66186
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.66186
PRR18 proline rich 18 2.66186
C1QL2 complement component 1, q subcomponent-like 2 2.66186
SIM2 single-minded family bHLH transcription factor 2 2.66186
TMEM235 transmembrane protein 235 2.66186
LOC124900192 uncharacterized LOC124900192 2.66186
KLHL33 kelch-like family member 33 2.66186
ATP13A5 ATPase type 13A5 2.66186
COL10A1 collagen, type X, alpha 1 2.66186
TBX22 T-box 22 2.66186
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.66186
CCR7 chemokine (C-C motif) receptor 7 2.66186
C15ORF62 chromosome 15 open reading frame 62 2.66186
SYT15 synaptotagmin XV 2.66186
ROPN1 rhophilin associated tail protein 1 2.66186
GDF6 growth differentiation factor 6 2.66186
NCLN nicalin 2.66186
FMR1NB fragile X mental retardation 1 neighbor 2.66186
C7ORF57 chromosome 7 open reading frame 57 2.66186
TACR2 tachykinin receptor 2 2.66186
CCR8 chemokine (C-C motif) receptor 8 2.66186
USH1G Usher syndrome 1G (autosomal recessive) 2.66186
BMP5 bone morphogenetic protein 5 2.66186
CARNS1 carnosine synthase 1 2.66186
GAL3ST2 galactose-3-O-sulfotransferase 2 2.66186
EDN3 endothelin 3 2.66186
GLOD5 glyoxalase domain containing 5 2.66186
SIT1 signaling threshold regulating transmembrane adaptor 1 2.66186
EFCAB9 EF-hand calcium binding domain 9 2.66186
SYNE3 spectrin repeat containing, nuclear envelope family member 3 2.66186
BTNL2 butyrophilin-like 2 2.66186
S100Z S100 calcium binding protein Z 2.66186
A3GALT2 alpha 1,3-galactosyltransferase 2 2.66186
ZNF471 zinc finger protein 471 2.66186
SLC7A4 solute carrier family 7, member 4 2.66186
ERP27 endoplasmic reticulum protein 27 2.66186
C9ORF50 chromosome 9 open reading frame 50 2.66186
ALOX15B arachidonate 15-lipoxygenase, type B 2.66186
PRR15L proline rich 15-like 2.66186
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.66186
NTSR2 neurotensin receptor 2 2.66186
HSPB9 heat shock protein, alpha-crystallin-related, B9 2.66186
KLF1 Kruppel-like factor 1 (erythroid) 2.66186
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.66186
EVPLL envoplakin-like 2.66186
QRFP pyroglutamylated RFamide peptide 2.66186
CCNI2 cyclin I family, member 2 2.66186
ORM2 orosomucoid 2 2.66186
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.66186
DRC1 dynein regulatory complex subunit 1 2.66186
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 2.66186
GOLGA8R golgin A8 family, member R 2.66186
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.66186
TMPPE transmembrane protein with metallophosphoesterase domain 2.66186
BCL2L15 BCL2-like 15 2.66186
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.66186
KISS1 KiSS-1 metastasis-suppressor 2.66186
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.66186
ZCCHC12 zinc finger, CCHC domain containing 12 2.66186
SIAH3 siah E3 ubiquitin protein ligase family member 3 2.66186
KLK6 kallikrein-related peptidase 6 2.66186
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.66186
LYZ lysozyme 2.66186
LPCAT2 lysophosphatidylcholine acyltransferase 2 2.66186
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.66186
BOLA2 bolA family member 2 2.66186
DNAH2 dynein, axonemal, heavy chain 2 2.66186
KRTAP12-2 keratin associated protein 12-2 2.66186
PITX2 paired-like homeodomain 2 2.66186
TMPRSS12 transmembrane (C-terminal) protease, serine 12 2.66186
AREG amphiregulin 2.66186
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.66186
ADAM29 ADAM metallopeptidase domain 29 2.66186
NLRP9 NLR family, pyrin domain containing 9 2.66186
MMP13 matrix metallopeptidase 13 2.66186
NLRP3 NLR family, pyrin domain containing 3 2.66186
ZNF396 zinc finger protein 396 2.66186
AKR1C2 aldo-keto reductase family 1, member C2 2.66186
CIB4 calcium and integrin binding family member 4 2.66186
SGMS2 sphingomyelin synthase 2 2.66186
OR56B4 olfactory receptor, family 56, subfamily B, member 4 2.66186
PATE2 prostate and testis expressed 2 2.66186
CSNK2A2 casein kinase 2, alpha prime polypeptide 2.66186
C4BPA complement component 4 binding protein, alpha 2.66186
SPACA5 sperm acrosome associated 5 2.66186
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 2.66186
PATE1 prostate and testis expressed 1 2.66186
DMRTC1 DMRT-like family C1 2.66186
TUBAL3 tubulin, alpha-like 3 2.66186
TOR1AIP1 torsin A interacting protein 1 2.64443
WDR31 WD repeat domain 31 2.64443
SHE Src homology 2 domain containing E 2.53196
CCDC159 coiled-coil domain containing 159 2.53196
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 2.44736
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2.44509
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 2.43136
TBCD tubulin folding cofactor D 2.42328
SLC33A2 solute carrier family 33 member 2 2.41707
PCDHB2 protocadherin beta 2 2.41458
BKGD beta-keto-L-gulonate decarboxylase 2.39859
ZCCHC24 zinc finger, CCHC domain containing 24 2.37484
REN renin 2.33308
SLC25A38 solute carrier family 25, member 38 2.32748
RARA retinoic acid receptor, alpha 2.32377
CDKL3 cyclin-dependent kinase-like 3 2.32003
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) 2.29681
MLXIPL MLX interacting protein-like 2.29681
LDB2 LIM domain binding 2 2.29218
RPS12 ribosomal protein S12 2.27671
SRPK1 SRSF protein kinase 1 2.27155
NLGN1 neuroligin 1 2.26771
ARHGAP6 Rho GTPase activating protein 6 2.26188
CRB3 crumbs family member 3 2.25484
DNAH14 dynein, axonemal, heavy chain 14 2.23624
BTN3A2 butyrophilin, subfamily 3, member A2 2.23431
SCFD1 sec1 family domain containing 1 2.22959
BORA bora, aurora kinase A activator 2.22009
ZNG1E Zn regulated GTPase metalloprotein activator 1E 2.20074
GFPT2 glutamine-fructose-6-phosphate transaminase 2 2.19906
TCN2 transcobalamin II 2.18672
GPHRB golgi pH regulator B 2.18672
ALKBH3 alkB, alkylation repair homolog 3 (E. coli) 2.12432
TMEM143 transmembrane protein 143 2.11546
MAN1A2 mannosidase, alpha, class 1A, member 2 2.09943
CTH cystathionine gamma-lyase 2.09533
OPRD1 opioid receptor, delta 1 2.08123
FANCD2 Fanconi anemia, complementation group D2 2.07558
EXD3 exonuclease 3'-5' domain containing 3 2.07377
CYB5R4 cytochrome b5 reductase 4 2.07054
MTMR2 myotubularin related protein 2 2.06767
GPBP1 GC-rich promoter binding protein 1 2.06362
METTL1 methyltransferase like 1 2.06336
ERVK3-1 endogenous retrovirus group K3, member 1 2.05784
KCTD14 potassium channel tetramerization domain containing 14 2.0542
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 2.053
NR6A1 nuclear receptor subfamily 6, group A, member 1 2.053
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 2.04309
PPCS phosphopantothenoylcysteine synthetase 2.02705
SRSF12 serine/arginine-rich splicing factor 12 2.02378
ZNF395 zinc finger protein 395 2.01468
COL8A2 collagen, type VIII, alpha 2 2.00991
ERCC1 excision repair cross-complementation group 1 2.00991

decreased expression

Symbol Name Standardized Value
SLC14A2 solute carrier family 14 (urea transporter), member 2 -2.72187
KLHL17 kelch-like family member 17 -2.72187
IQCN IQ motif containing N -2.66186
TMC3 transmembrane channel-like 3 -2.66186
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -2.66186
MTERF4 mitochondrial transcription termination factor 4 -2.66186
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -2.66186
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -2.66186
DGKI diacylglycerol kinase, iota -2.66186
FGF8 fibroblast growth factor 8 (androgen-induced) -2.66186
TGM2 transglutaminase 2 -2.66186
RGPD5 RANBP2-like and GRIP domain containing 5 -2.66186
ACAN aggrecan -2.66186
C10ORF90 chromosome 10 open reading frame 90 -2.66186
USP32 ubiquitin specific peptidase 32 -2.66186
TMEM79 transmembrane protein 79 -2.66186
NLRP10 NLR family, pyrin domain containing 10 -2.66186
NAXE NAD(P)HX epimerase -2.66186
MIX23 mitochondrial matrix import factor 23 -2.66186
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 -2.66186
PCDHGA9 protocadherin gamma subfamily A, 9 -2.66186
BNC1 basonuclin 1 -2.66186
MFSD1 major facilitator superfamily domain containing 1 -2.66186
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 -2.66186
ADGRG1 adhesion G protein-coupled receptor G1 -2.66186
ZNF431 zinc finger protein 431 -2.66186
MICALL2 MICAL-like 2 -2.66186
ARHGAP30 Rho GTPase activating protein 30 -2.66186
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 -2.66186
CXCL2 chemokine (C-X-C motif) ligand 2 -2.66186
NGFR nerve growth factor receptor -2.66186
EBF3 early B-cell factor 3 -2.66186
PRKACB protein kinase, cAMP-dependent, catalytic, beta -2.66186
F2RL2 coagulation factor II (thrombin) receptor-like 2 -2.66186
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -2.66186
KLF4 Kruppel-like factor 4 (gut) -2.66186
EPHA5 EPH receptor A5 -2.66186
PCDHAC1 protocadherin alpha subfamily C, 1 -2.66186
IGSF6 immunoglobulin superfamily, member 6 -2.66186
RBM24 RNA binding motif protein 24 -2.66186
EXD1 exonuclease 3'-5' domain containing 1 -2.66186
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -2.66186
BTNL8 butyrophilin-like 8 -2.66186
AMH anti-Mullerian hormone -2.66186
ZNF837 zinc finger protein 837 -2.66186
CNTF ciliary neurotrophic factor -2.66186
SIPA1L2 signal-induced proliferation-associated 1 like 2 -2.65232
NGRN neugrin, neurite outgrowth associated -2.64443
TUBGCP4 tubulin, gamma complex associated protein 4 -2.63988
CLK2 CDC-like kinase 2 -2.61654
TENT5C terminal nucleotidyltransferase 5C -2.61654
CORT cortistatin -2.61654
GRM7 glutamate receptor, metabotropic 7 -2.61111
TBC1D12 TBC1 domain family, member 12 -2.58504
PNN pinin, desmosome associated protein -2.53196
CLMN calmin (calponin-like, transmembrane) -2.52899
WDR70 WD repeat domain 70 -2.48414
FZD7 frizzled class receptor 7 -2.44736
BCAP29 B-cell receptor-associated protein 29 -2.44509
TFR2 transferrin receptor 2 -2.412
C12ORF42 chromosome 12 open reading frame 42 -2.41066
FIG4 FIG4 phosphoinositide 5-phosphatase -2.38101
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.3625
ZNF723 zinc finger protein 723 -2.32822
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) -2.32377
SLC35H1 solute carrier family 35 member H1 -2.28327
SMG7 SMG7 nonsense mediated mRNA decay factor -2.27671
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) -2.2634
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -2.25404
PCDH17 protocadherin 17 -2.23431
NEURL1 neuralized E3 ubiquitin protein ligase 1 -2.23431
SPICP3 Spi-C transcription factor pseudogene 3 -2.22959
DPF2 D4, zinc and double PHD fingers family 2 -2.22959
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -2.22959
FERMT1 fermitin family member 1 -2.21163
LRP10 low density lipoprotein receptor-related protein 10 -2.19616
DENND2D DENN/MADD domain containing 2D -2.18413
SARAF store-operated calcium entry-associated regulatory factor -2.14613
B4GAT1-DT B4GAT1 divergent transcript -2.14233
LOXL2 lysyl oxidase-like 2 -2.14196
ZNF526 zinc finger protein 526 -2.13747
FAM174A family with sequence similarity 174, member A -2.1299
SEC23B Sec23 homolog B (S. cerevisiae) -2.12666
DUSP1 dual specificity phosphatase 1 -2.11546
PKN1 protein kinase N1 -2.11546
CHERP calcium homeostasis endoplasmic reticulum protein -2.11546
SRRD SRR1 domain containing -2.1134
STK35 serine/threonine kinase 35 -2.10952
SH3GLB1 SH3-domain GRB2-like endophilin B1 -2.10952
ANKRD13B ankyrin repeat domain 13B -2.10952
CHMP4B charged multivesicular body protein 4B -2.09847
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 -2.08335
NMT2 N-myristoyltransferase 2 -2.07503
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.07377
C3ORF38 chromosome 3 open reading frame 38 -2.07054
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.06481
RCOR2 REST corepressor 2 -2.05784
RMI1 RecQ mediated genome instability 1 -2.05784
ACOT13 acyl-CoA thioesterase 13 -2.05414
POR P450 (cytochrome) oxidoreductase -2.05414
RNF114 ring finger protein 114 -2.053
CR2 complement component (3d/Epstein Barr virus) receptor 2 -2.04713
ZDHHC8 zinc finger, DHHC-type containing 8 -2.04309
ZNF846 zinc finger protein 846 -2.04309
RXYLT1 ribitol xylosyltransferase 1 -2.01899
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 -2.00388
STX19 syntaxin 19 -2.00388