| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the MK-886-264 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AJAP1 | adherens junctions associated protein 1 |
| ARHGAP19 | Rho GTPase activating protein 19 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ATM | ATM serine/threonine kinase |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BRAP | BRCA1 associated protein |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CASKIN2 | CASK interacting protein 2 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CD5 | CD5 molecule |
| CDC25A | cell division cycle 25A |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CLDN17 | claudin 17 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DCAF8 | DDB1 and CUL4 associated factor 8 |
| DCC | DCC netrin 1 receptor |
| DDR2 | discoidin domain receptor tyrosine kinase 2 |
| DMWD | dystrophia myotonica, WD repeat containing |
| EFCAB1 | EF-hand calcium binding domain 1 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| ESR1 | estrogen receptor 1 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FNDC3A | fibronectin type III domain containing 3A |
| FOLR2 | folate receptor 2 (fetal) |
| FOXO1 | forkhead box O1 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GALR3 | galanin receptor 3 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRM2 | glutamate receptor, metabotropic 2 |
| HDC | histidine decarboxylase |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFT122 | intraflagellar transport 122 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL5RA | interleukin 5 receptor, alpha |
| IRF8 | interferon regulatory factor 8 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| KRT6B | keratin 6B, type II |
| L1CAM | L1 cell adhesion molecule |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 |
| LOC441601 | septin 7 pseudogene |
| MALL | mal, T-cell differentiation protein-like |
| MAP1A | microtubule-associated protein 1A |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NNAT | neuronatin |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PIP | prolactin-induced protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PQLC3 | PQ loop repeat containing 3 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRSS53 | protease, serine, 53 |
| RAPGEF3 | Rap guanine nucleotide exchange factor (GEF) 3 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SNX1 | sorting nexin 1 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPIN2A | spindlin family, member 2A |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNGR1 | synaptogyrin 1 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| TMF1 | TATA element modulatory factor 1 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TXNL4A | thioredoxin-like 4A |
| VRK3 | vaccinia related kinase 3 |
| YIPF6 | Yip1 domain family, member 6 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF287 | zinc finger protein 287 |
| ZNF3 | zinc finger protein 3 |
| ZNF358 | zinc finger protein 358 |
| ZNF460 | zinc finger protein 460 |
| Symbol | Name |
|---|---|
| ACP5 | acid phosphatase 5, tartrate resistant |
| ADRB2 | adrenoceptor beta 2, surface |
| ALX3 | ALX homeobox 3 |
| AMN | amnion associated transmembrane protein |
| ARRB2 | arrestin, beta 2 |
| ASGR2 | asialoglycoprotein receptor 2 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ASIP | agouti signaling protein |
| BCO1 | beta-carotene oxygenase 1 |
| BHMT | betaine--homocysteine S-methyltransferase |
| C19ORF57 | chromosome 19 open reading frame 57 |
| C20ORF195 | chromosome 20 open reading frame 195 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC176 | coiled-coil domain containing 176 |
| CCL11 | chemokine (C-C motif) ligand 11 |
| CD70 | CD70 molecule |
| CDH22 | cadherin 22, type 2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CENPQ | centromere protein Q |
| CNPY3 | canopy FGF signaling regulator 3 |
| CRHBP | corticotropin releasing hormone binding protein |
| CRYAB | crystallin, alpha B |
| CST5 | cystatin D |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP13 | dual specificity phosphatase 13 |
| ECE2 | endothelin converting enzyme 2 |
| EPX | eosinophil peroxidase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGF16 | fibroblast growth factor 16 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FTCD | formimidoyltransferase cyclodeaminase |
| GCM1 | glial cells missing homolog 1 (Drosophila) |
| GDF3 | growth differentiation factor 3 |
| GDF5 | growth differentiation factor 5 |
| GPR63 | G protein-coupled receptor 63 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HMX1 | H6 family homeobox 1 |
| HTR1A | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled |
| HYDIN | HYDIN, axonemal central pair apparatus protein |
| IFNA5 | interferon, alpha 5 |
| IL9 | interleukin 9 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCNQ4 | potassium channel, voltage gated KQT-like subfamily Q, member 4 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLHDC8A | kelch domain containing 8A |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KRT75 | keratin 75, type II |
| LENEP | lens epithelial protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MAGEA5 | melanoma antigen family A5 |
| MTMR10 | myotubularin related protein 10 |
| MTNR1A | melatonin receptor 1A |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| NOL12 | nucleolar protein 12 |
| NRIP2 | nuclear receptor interacting protein 2 |
| OPRD1 | opioid receptor, delta 1 |
| OR1E1 | olfactory receptor, family 1, subfamily E, member 1 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PDE11A | phosphodiesterase 11A |
| PHOX2A | paired-like homeobox 2a |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PRDM14 | PR domain containing 14 |
| PRPS1L1 | phosphoribosyl pyrophosphate synthetase 1-like 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTK6 | protein tyrosine kinase 6 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| REG1P | regenerating islet-derived 1 pseudogene |
| RIMBP2 | RIMS binding protein 2 |
| RIN2 | Ras and Rab interactor 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPEG | SPEG complex locus |
| SPRR3 | small proline-rich protein 3 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIM68 | tripartite motif containing 68 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| XYLT2 | xylosyltransferase II |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
| ZFR2 | zinc finger RNA binding protein 2 |
| ZNF134 | zinc finger protein 134 |
| ZNF639 | zinc finger protein 639 |
