| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the MK-886-601 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACVR1B | activin A receptor, type IB |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BAX | BCL2-associated X protein |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BRAP | BRCA1 associated protein |
| C10ORF76 | chromosome 10 open reading frame 76 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CCDC87 | coiled-coil domain containing 87 |
| CD86 | CD86 molecule |
| CLIC4 | chloride intracellular channel 4 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRYAB | crystallin, alpha B |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| ENG | endoglin |
| ERCC4 | excision repair cross-complementation group 4 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GPATCH4 | G patch domain containing 4 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HLA-G | major histocompatibility complex, class I, G |
| HMX1 | H6 family homeobox 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL1B | interleukin 1, beta |
| IL2RG | interleukin 2 receptor, gamma |
| IL7R | interleukin 7 receptor |
| KLHL28 | kelch-like family member 28 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOC647070 | uncharacterized LOC647070 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAPK1 | mitogen-activated protein kinase 1 |
| MAX | MYC associated factor X |
| MED28 | mediator complex subunit 28 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NF1 | neurofibromin 1 |
| NNAT | neuronatin |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHF20 | PHD finger protein 20 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLXNB1 | plexin B1 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKCA | protein kinase C, alpha |
| RAB11B | RAB11B, member RAS oncogene family |
| RORC | RAR-related orphan receptor C |
| RPS2 | ribosomal protein S2 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SDC2 | syndecan 2 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SH3BP2 | SH3-domain binding protein 2 |
| SLA | Src-like-adaptor |
| SLC43A3 | solute carrier family 43, member 3 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPIN2A | spindlin family, member 2A |
| SPRR1B | small proline-rich protein 1B |
| SUGP2 | SURP and G patch domain containing 2 |
| SUSD4 | sushi domain containing 4 |
| SVIL | supervillin |
| SYT17 | synaptotagmin XVII |
| T | T, brachyury homolog (mouse) |
| TBX21 | T-box 21 |
| TSPAN32 | tetraspanin 32 |
| TUBA4B | tubulin, alpha 4b |
| USP34 | ubiquitin specific peptidase 34 |
| WDR48 | WD repeat domain 48 |
| XYLT2 | xylosyltransferase II |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZMYM6 | zinc finger, MYM-type 6 |
| ZNF250 | zinc finger protein 250 |
| ZNF473 | zinc finger protein 473 |
| ZNF589 | zinc finger protein 589 |
| ZNF91 | zinc finger protein 91 |
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 |
| ADM2 | adrenomedullin 2 |
| AHR | aryl hydrocarbon receptor |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALLC | allantoicase |
| AMT | aminomethyltransferase |
| AURKC | aurora kinase C |
| AXIN1 | axin 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| BEAN1 | brain expressed, associated with NEDD4, 1 |
| BEX1 | brain expressed, X-linked 1 |
| BNC1 | basonuclin 1 |
| BTNL3 | butyrophilin-like 3 |
| C4BPA | complement component 4 binding protein, alpha |
| CAV3 | caveolin 3 |
| CCDC71 | coiled-coil domain containing 71 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CENPQ | centromere protein Q |
| COBL | cordon-bleu WH2 repeat protein |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CRIPT | cysteine-rich PDZ-binding protein |
| CSN2 | casein beta |
| CTSK | cathepsin K |
| DLK1 | delta-like 1 homolog (Drosophila) |
| EDA2R | ectodysplasin A2 receptor |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM188A | family with sequence similarity 188, member A |
| FAM214B | family with sequence similarity 214, member B |
| FAM76A | family with sequence similarity 76, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO2 | F-box protein 2 |
| FOXD1 | forkhead box D1 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HBD | hemoglobin, delta |
| HHLA1 | HERV-H LTR-associating 1 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) |
| INA | internexin neuronal intermediate filament protein, alpha |
| IRF2 | interferon regulatory factor 2 |
| KIFC3 | kinesin family member C3 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC15 | leucine rich repeat containing 15 |
| MAP2 | microtubule-associated protein 2 |
| MMP2 | matrix metallopeptidase 2 |
| MT3 | metallothionein 3 |
| MVP | major vault protein |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PDE8B | phosphodiesterase 8B |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PRRX1 | paired related homeobox 1 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RASIP1 | Ras interacting protein 1 |
| RELN | reelin |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SND1-IT1 | SND1 intronic transcript 1 |
| SRPX | sushi-repeat containing protein, X-linked |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM206 | transmembrane protein 206 |
| TMEM39A | transmembrane protein 39A |
| TNS2 | tensin 2 |
| TOR4A | torsin family 4, member A |
| TRIM8 | tripartite motif containing 8 |
| UBQLN4 | ubiquilin 4 |
| ULBP1 | UL16 binding protein 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR19 | WD repeat domain 19 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED2 | zinc finger, BED-type containing 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZNF134 | zinc finger protein 134 |
| ZNF34 | zinc finger protein 34 |
| ZNF770 | zinc finger protein 770 |
| ZNF816 | zinc finger protein 816 |
