MKI67 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description marker of proliferation Ki-67|This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 4288)
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Genes

282 genes differentially expressed following the MKI67 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
KLHL30 kelch-like family member 30 2.72482
SCG2 secretogranin II 2.72482
OR8A1 olfactory receptor, family 8, subfamily A, member 1 2.72482
SLC16A11 solute carrier family 16, member 11 2.72482
TRIM10 tripartite motif containing 10 2.72482
PCDHB6 protocadherin beta 6 2.72482
GLYAT glycine-N-acyltransferase 2.72482
CLEC19A C-type lectin domain family 19, member A 2.72482
CXORF65 chromosome X open reading frame 65 2.72482
USP26 ubiquitin specific peptidase 26 2.72482
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.72482
CAPN14 calpain 14 2.72482
RS1 retinoschisin 1 2.72482
GRXCR1 glutaredoxin, cysteine rich 1 2.72482
KLHL35 kelch-like family member 35 2.72482
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.72482
TMPRSS11E transmembrane protease, serine 11E 2.72482
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.72482
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2.72482
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.72482
MEI1 meiosis inhibitor 1 2.72482
MFAP5 microfibrillar associated protein 5 2.72482
SMIM5 small integral membrane protein 5 2.72482
MEIKIN meiotic kinetochore factor 2.72482
TRIM42 tripartite motif containing 42 2.72482
GMNC geminin coiled-coil domain containing 2.72482
S100A1 S100 calcium binding protein A1 2.72482
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.72482
CRYGA crystallin, gamma A 2.72482
TBATA thymus, brain and testes associated 2.72482
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.72482
RGPD4 RANBP2-like and GRIP domain containing 4 2.72482
C19ORF67 chromosome 19 open reading frame 67 2.72482
GPR26 G protein-coupled receptor 26 2.72482
MYOM3 myomesin 3 2.72482
TCAF2 TRPM8 channel-associated factor 2 2.72482
OTUD6A OTU deubiquitinase 6A 2.72482
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.72482
NOTUM notum pectinacetylesterase homolog (Drosophila) 2.72482
C3ORF22 chromosome 3 open reading frame 22 2.72482
TMCO5A transmembrane and coiled-coil domains 5A 2.72482
SERTM2 serine rich and transmembrane domain containing 2 2.72482
YIPF7 Yip1 domain family, member 7 2.72482
ROPN1B rhophilin associated tail protein 1B 2.72482
ALX3 ALX homeobox 3 2.72482
CFAP97 cilia and flagella associated protein 97 2.72482
STMN4 stathmin-like 4 2.72482
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 2.72482
TMPRSS6 transmembrane protease, serine 6 2.72482
SPAAR small regulatory polypeptide of amino acid response 2.72482
GBP6 guanylate binding protein family, member 6 2.72482
NECTIN4 nectin cell adhesion molecule 4 2.72482
CFAP276 cilia and flagella associated protein 276 2.72482
GARIN3 golgi associated RAB2B interactor family member 3 2.72482
H1-8 H1.8 linker histone 2.72482
CFAP97D1 CFAP97 domain containing 1 2.72482
CCN5 cellular communication network factor 5 2.72482
LHFPL6 LHFPL tetraspan subfamily member 6 2.72482
TCIM transcriptional and immune response regulator 2.72482
ASDURF ASNSD1 upstream open reading frame 2.72482
PAPOLB poly(A) polymerase beta (testis specific) 2.72482
GCSAM germinal center-associated, signaling and motility 2.72482
CD70 CD70 molecule 2.72482
LSP1 lymphocyte-specific protein 1 2.72482
FAM186A family with sequence similarity 186, member A 2.72482
C1QTNF1 C1q and tumor necrosis factor related protein 1 2.72482
LEF1 lymphoid enhancer-binding factor 1 2.72482
TLR4 toll-like receptor 4 2.72482
ZNF575 zinc finger protein 575 2.72482
ANXA13 annexin A13 2.72482
CALCA calcitonin-related polypeptide alpha 2.72482
MYOT myotilin 2.72482
INSRR insulin receptor-related receptor 2.72482
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 2.72482
PRDM7 PR domain containing 7 2.72482
PRG3 proteoglycan 3 2.72482
ROPN1 rhophilin associated tail protein 1 2.72482
ARMC12 armadillo repeat containing 12 2.72482
RGS21 regulator of G-protein signaling 21 2.72482
CDSN corneodesmosin 2.72482
NPFF neuropeptide FF-amide peptide precursor 2.72482
PCDHB11 protocadherin beta 11 2.72482
CFH complement factor H 2.72482
GOLGA6B golgin A6 family, member B 2.72482
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 2.72482
F2RL2 coagulation factor II (thrombin) receptor-like 2 2.72482
F2RL3 coagulation factor II (thrombin) receptor-like 3 2.72482
FAM177B family with sequence similarity 177, member B 2.72482
AKNAD1 AKNA domain containing 1 2.72482
CPA4 carboxypeptidase A4 2.72482
TREH trehalase (brush-border membrane glycoprotein) 2.72482
KLF2 Kruppel-like factor 2 2.72482
ANKRD60 ankyrin repeat domain 60 2.72482
MAGEF1 melanoma antigen family F1 2.72482
MORC1 MORC family CW-type zinc finger 1 2.72482
ENDOU endonuclease, polyU-specific 2.72482
KCNK4 potassium channel, two pore domain subfamily K, member 4 2.72482
OR56A4 olfactory receptor, family 56, subfamily A, member 4 2.72482
TESPA1 thymocyte expressed, positive selection associated 1 2.72482
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.72482
ANKRD65 ankyrin repeat domain 65 2.72482
PSKH2 protein serine kinase H2 2.72482
NUPR1 nuclear protein, transcriptional regulator, 1 2.72482
PGR progesterone receptor 2.72482
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.72482
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.72482
IL27 interleukin 27 2.72482
C1ORF185 chromosome 1 open reading frame 185 2.72482
TTC28 tetratricopeptide repeat domain 28 2.72482
GOLGA8K golgin A8 family, member K 2.72482
KRTAP2-2 keratin associated protein 2-2 2.72482
IZUMO1R IZUMO1 receptor, JUNO 2.72482
NOBOX NOBOX oogenesis homeobox 2.72482
VWA3A von Willebrand factor A domain containing 3A 2.72482
COMP cartilage oligomeric matrix protein 2.72482
KLK11 kallikrein-related peptidase 11 2.72482
EGR2 early growth response 2 2.72482
TPPP3 tubulin polymerization-promoting protein family member 3 2.72482
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.72482
CTSF cathepsin F 2.72482
PRTN3 proteinase 3 2.72482
MCIDAS multiciliate differentiation and DNA synthesis associated cell cycle protein 2.72482
TSPAN32 tetraspanin 32 2.72482
PLGLB2 plasminogen-like B2 2.72482
STEAP4 STEAP family member 4 2.72482
ADGRF5 adhesion G protein-coupled receptor F5 2.72482
NWD1 NACHT and WD repeat domain containing 1 2.72482
LRRC74B leucine rich repeat containing 74B 2.72482
TMEM86A transmembrane protein 86A 2.72482
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial 2.72482
ZBED6 zinc finger, BED-type containing 6 2.72482
PPP1R9A protein phosphatase 1, regulatory subunit 9A 2.72482
ANXA8 annexin A8 2.72482
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.72482
AGBL4 ATP/GTP binding protein-like 4 2.72482
ADRA1B adrenoceptor alpha 1B 2.72482
NUTM2A NUT family member 2A 2.72482
TGM7 transglutaminase 7 2.72482
FIGLA folliculogenesis specific basic helix-loop-helix 2.72482
CORO6 coronin 6 2.72482
RUFY4 RUN and FYVE domain containing 4 2.72482
TMEM52B transmembrane protein 52B 2.72482
SPNS3 spinster homolog 3 (Drosophila) 2.72482
CARD9 caspase recruitment domain family, member 9 2.72482
OR14A2 olfactory receptor, family 14, subfamily A, member 2 2.72482
ADIRF adipogenesis regulatory factor 2.72482
NPC1L1 NPC1-like 1 2.72482
TMEM184A transmembrane protein 184A 2.72482
TMEM272 transmembrane protein 272 2.7002
ELMOD1 ELMO/CED-12 domain containing 1 2.7002
SACK1B scaffolding CK1 anchoring protein B 2.66143
EDIL3 EGF-like repeats and discoidin I-like domains 3 2.61216
POC1A POC1 centriolar protein A 2.61216
SAMD3 sterile alpha motif domain containing 3 2.60047
INKA2 inka box actin regulator 2 2.48702
PPIG peptidylprolyl isomerase G (cyclophilin G) 2.48591
NRG1 neuregulin 1 2.40998
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.40612
GPR37L1 G protein-coupled receptor 37 like 1 2.39923
CCR3 chemokine (C-C motif) receptor 3 2.39185
DDB2 damage-specific DNA binding protein 2, 48kDa 2.35983
CALR calreticulin 2.32569
SPIN1 spindlin 1 2.29138
SNX21 sorting nexin family member 21 2.28977
DIAPH3 diaphanous-related formin 3 2.2545
DOCK3 dedicator of cytokinesis 3 2.24712
TENT5D terminal nucleotidyltransferase 5D 2.2456
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 2.22735
KREMEN2 kringle containing transmembrane protein 2 2.21027
EIF3M eukaryotic translation initiation factor 3, subunit M 2.14515
SRFBP1 serum response factor binding protein 1 2.11656
TUBA1C tubulin, alpha 1c 2.11656
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2.10269
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.10269
LPCAT4 lysophosphatidylcholine acyltransferase 4 2.10084
ZNF20 zinc finger protein 20 2.093
GCSH glycine cleavage system protein H (aminomethyl carrier) 2.0904
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 2.0781
DUSP1 dual specificity phosphatase 1 2.04265
RBM39 RNA binding motif protein 39 2.04265
ZNF713 zinc finger protein 713 2.03132
USP45 ubiquitin specific peptidase 45 2.01491
QPCTL glutaminyl-peptide cyclotransferase-like 2.00689
ELAVL1 ELAV like RNA binding protein 1 2.00662

decreased expression

Symbol Name Standardized Value
SYNJ1 synaptojanin 1 -2.72482
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 -2.72482
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.72482
KIF13A kinesin family member 13A -2.72482
AZU1 azurocidin 1 -2.72482
NME8 NME/NM23 family member 8 -2.72482
FAM178B family with sequence similarity 178, member B -2.72482
RARA retinoic acid receptor, alpha -2.72482
INKA1 inka box actin regulator 1 -2.72482
SPON2 spondin 2, extracellular matrix protein -2.72482
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 -2.72482
MRGBP MRG/MORF4L binding protein -2.72482
ZNF630 zinc finger protein 630 -2.72482
AGRN agrin -2.72482
ADRA1A adrenoceptor alpha 1A -2.72482
LTB4R leukotriene B4 receptor -2.72482
DHDH dihydrodiol dehydrogenase (dimeric) -2.72482
ZNF554 zinc finger protein 554 -2.72482
MSN moesin -2.70098
NLRP7 NLR family, pyrin domain containing 7 -2.7002
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.7002
FGF4 fibroblast growth factor 4 -2.7002
C1QL3 complement component 1, q subcomponent-like 3 -2.7002
LOC124906010 uncharacterized LOC124906010 -2.7002
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -2.7002
DAND5 DAN domain family member 5, BMP antagonist -2.7002
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -2.7002
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.7002
NPIPB8 nuclear pore complex interacting protein family, member B8 -2.7002
POU2F3 POU class 2 homeobox 3 -2.7002
COL15A1 collagen, type XV, alpha 1 -2.7002
CTXND1 cortexin domain containing 1 -2.7002
GBX1 gastrulation brain homeobox 1 -2.7002
CFAP100 cilia and flagella associated protein 100 -2.7002
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -2.7002
CSF1R colony stimulating factor 1 receptor -2.7002
IP6K3 inositol hexakisphosphate kinase 3 -2.7002
COL9A2 collagen, type IX, alpha 2 -2.7002
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B -2.7002
VSTM1 V-set and transmembrane domain containing 1 -2.7002
TRPV5 transient receptor potential cation channel, subfamily V, member 5 -2.7002
BTLA B and T lymphocyte associated -2.7002
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -2.7002
ZNF703 zinc finger protein 703 -2.7002
GLUD2 glutamate dehydrogenase 2 -2.7002
RSAD2 radical S-adenosyl methionine domain containing 2 -2.7002
SPEF2 sperm flagellar 2 -2.69887
ZNF34 zinc finger protein 34 -2.61097
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -2.61097
ARL16 ADP-ribosylation factor-like 16 -2.60662
OR1F1 olfactory receptor, family 1, subfamily F, member 1 -2.59511
STARD3NL STARD3 N-terminal like -2.59511
FAAH2 fatty acid amide hydrolase 2 -2.58728
HTRA3 HtrA serine peptidase 3 -2.56307
EVI2B ecotropic viral integration site 2B -2.54242
PKP3 plakophilin 3 -2.54242
CBX4 chromobox homolog 4 -2.53539
TADA2B transcriptional adaptor 2B -2.51013
DCAF10 DDB1 and CUL4 associated factor 10 -2.45907
COL4A1 collagen, type IV, alpha 1 -2.42976
ZNF79 zinc finger protein 79 -2.42164
HEXB hexosaminidase B (beta polypeptide) -2.39923
TXNRD1 thioredoxin reductase 1 -2.39185
NGF nerve growth factor (beta polypeptide) -2.3877
MYL5 myosin, light chain 5, regulatory -2.3877
STK31 serine/threonine kinase 31 -2.37348
SLC39A11 solute carrier family 39, member 11 -2.37152
C1ORF50 chromosome 1 open reading frame 50 -2.3652
ZFAND3 zinc finger, AN1-type domain 3 -2.35588
ZC3H14 zinc finger CCCH-type containing 14 -2.35323
ANXA11 annexin A11 -2.32569
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 -2.30418
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -2.29904
PCNA proliferating cell nuclear antigen -2.29674
NPIPB13 nuclear pore complex interacting protein family, member B13 -2.29199
VASP vasodilator-stimulated phosphoprotein -2.2326
ENPEP glutamyl aminopeptidase (aminopeptidase A) -2.21896
MKI67 marker of proliferation Ki-67 -2.19035
ABTB1 ankyrin repeat and BTB (POZ) domain containing 1 -2.18479
ADCY10 adenylate cyclase 10 (soluble) -2.18479
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -2.15865
CD99L2 CD99 molecule-like 2 -2.1279
SPATA33 spermatogenesis associated 33 -2.11962
TUBG2 tubulin, gamma 2 -2.11823
MIGA2 mitoguardin 2 -2.0904
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial -2.0904
ZC3H12B zinc finger CCCH-type containing 12B -2.08444
SLC37A3 solute carrier family 37, member 3 -2.07854
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.06037
STRA6 stimulated by retinoic acid 6 -2.05796
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -2.04265
URGCP upregulator of cell proliferation -2.04243
HOMER2 homer scaffolding protein 2 -2.0142
MEX3C mex-3 RNA binding family member C -2.01276
PROZ protein Z, vitamin K-dependent plasma glycoprotein -2.00689
ART3 ADP-ribosyltransferase 3 -2.00689
CFAP61 cilia and flagella associated protein 61 -2.00689
STK39 serine threonine kinase 39 -2.0041