MKN45 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Human gastric adenocarcinoma, established from the poorly differentiated adenocarcinoma of the stomach (medullary type) of a 62-year-old woman. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001225)
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Genes

145 genes with high or low copy number in MKN45 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
MIR610 microRNA 610 4.51153
CCDC34 coiled-coil domain containing 34 4.51153
LIN7C lin-7 homolog C (C. elegans) 4.51153
BDNF brain-derived neurotrophic factor 4.51153
KIF18A kinesin family member 18A 4.51153
LINC00678 long intergenic non-protein coding RNA 678 4.51153
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 4.51153
BDNF-AS BDNF antisense RNA 4.51153
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 3.12177
FIBIN fin bud initiation factor homolog (zebrafish) 3.12177
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 3.12177
ANO3 anoctamin 3 2.76305
OMP olfactory marker protein 2.49065
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 2.49065
FEZF1 FEZ family zinc finger 1 2.49065
CADPS2 Ca++-dependent secretion activator 2 2.49065
FEZF1-AS1 FEZF1 antisense RNA 1 2.49065
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 2.49065
CAPN5 calpain 5 2.49065
MYO7A myosin VIIA 2.44392
FAM3C family with sequence similarity 3, member C 2.44392
WNT16 wingless-type MMTV integration site family, member 16 2.44392
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.41451
CPED1 cadherin-like and PC-esterase domain containing 1 2.39327
TSPAN12 tetraspanin 12 2.39327
GDPD4 glycerophosphodiester phosphodiesterase domain containing 4 2.39327
MIR3666 microRNA 3666 2.39327
ING3 inhibitor of growth family, member 3 2.39327
MDFIC MyoD family inhibitor domain containing 2.36889
FOXP2 forkhead box P2 2.36889
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 2.36889
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 2.35236
ANKRD7 ankyrin repeat domain 7 2.283
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 2.283
TES testin LIM domain protein 2.26395
TFEC transcription factor EC 2.26395
CAV2 caveolin 2 2.25904
WNT2 wingless-type MMTV integration site family member 2 2.25904
CTTNBP2 cortactin binding protein 2 2.25904
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.25904
ST7-OT3 ST7 overlapping transcript 3 2.25904
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 2.25904
ST7-AS2 ST7 antisense RNA 2 2.24845
CAV1 caveolin 1, caveolae protein, 22kDa 2.24845
ST7-OT4 ST7 overlapping transcript 4 2.24139
ST7 suppression of tumorigenicity 7 2.24139
ST7-AS1 ST7 antisense RNA 1 2.24139
MET MET proto-oncogene, receptor tyrosine kinase 2.2355
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 2.2355
SNORA25 small nucleolar RNA, H/ACA box 25 2.15953
CCDC67 coiled-coil domain containing 67 2.12703
C11ORF54 chromosome 11 open reading frame 54 2.12703
CEP295 centrosomal protein 295kDa 2.12703
SNORA8 small nucleolar RNA, H/ACA box 8 2.12703
SMCO4 single-pass membrane protein with coiled-coil domains 4 2.12703
MIR1304 microRNA 1304 2.12703
SCARNA9 small Cajal body-specific RNA 9 2.12703
SNORA18 small nucleolar RNA, H/ACA box 18 2.12703
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.12703
LOC642414 tripartite motif containing 64B pseudogene 2.12527
TRIM49 tripartite motif containing 49 2.12506
GRM5 glutamate receptor, metabotropic 5 2.12484
GRM5-AS1 GRM5 antisense RNA 1 2.12439
TRIM53AP tripartite motif containing 53A, pseudogene 2.12439
JRKL JRK-like 2.12225
MIR1260B microRNA 1260b 2.12225
FOLH1B folate hydrolase 1B 2.12225
UBTFL1 upstream binding transcription factor, RNA polymerase I-like 1 2.12225
TRIM49C tripartite motif containing 49C 2.12225
JRKL-AS1 JRKL antisense RNA 1 2.12225
MIR5692A1 microRNA 5692a-1 2.12225
RAB38 RAB38, member RAS oncogene family 2.12225
TYR tyrosinase 2.12225
TRIM49D2P 2.12225
NOX4 NADPH oxidase 4 2.12225
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 2.12225
TRIM64B tripartite motif containing 64B 2.12225
CCDC82 coiled-coil domain containing 82 2.12225
MIR4490 microRNA 4490 2.12225
TRIM64 tripartite motif containing 64 2.12225
TRIM77 tripartite motif containing 77 2.12225
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 2.12225
CTSC cathepsin C 2.10992
FAT3 FAT atypical cadherin 3 2.10992
MAML2 mastermind-like 2 (Drosophila) 2.10992
AASS aminoadipate-semialdehyde synthase 2.09431
SNORD5 small nucleolar RNA, C/D box 5 2.08334
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2.06473
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.06473
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene) 2.06473
SNORA40 small nucleolar RNA, H/ACA box 40 2.05129

low copy number

Symbol Name Standardized Value
RGS11 regulator of G-protein signaling 11 -5.12655
ITFG3 integrin alpha FG-GAP repeat containing 3 -5.12655
HBA2 hemoglobin, alpha 2 -5.12655
RHBDF1 rhomboid 5 homolog 1 (Drosophila) -5.12655
HBA1 hemoglobin, alpha 1 -5.12655
HBQ1 hemoglobin, theta 1 -5.12655
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -5.12655
MPG N-methylpurine-DNA glycosylase -5.12655
HBM hemoglobin, mu -5.12655
HBZ hemoglobin, zeta -5.12655
DMTN dematin actin binding protein -3.7119
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 -3.7119
FAM160B2 family with sequence similarity 160, member B2 -3.7119
HR hair growth associated -3.7119
CPA6 carboxypeptidase A6 -3.40381
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 -3.2703
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 -3.24687
LUC7L LUC7-like (S. cerevisiae) -3.24687
YAP1 Yes-associated protein 1 -3.23157
KIF26B kinesin family member 26B -3.15836
PCNXL2 pecanex-like 2 (Drosophila) -3.14331
NTPCR nucleoside-triphosphatase, cancer-related -3.14331
OR2J2 olfactory receptor, family 2, subfamily J, member 2 -3.11641
PARK2 parkin RBR E3 ubiquitin protein ligase -2.85647
OR2T34 olfactory receptor, family 2, subfamily T, member 34 -2.84792
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -2.84635
SMAD4 SMAD family member 4 -2.82872
MACROD2-AS1 MACROD2 antisense RNA 1 -2.81384
LINGO2 leucine rich repeat and Ig domain containing 2 -2.79933
OR2T11 olfactory receptor, family 2, subfamily T, member 11 (gene/pseudogene) -2.78432
HACD4 3-hydroxyacyl-CoA dehydratase 4 -2.78237
OR2T10 olfactory receptor, family 2, subfamily T, member 10 -2.78237
IFNB1 interferon, beta 1, fibroblast -2.77588
IFNW1 interferon, omega 1 -2.77446
IZUMO3 IZUMO family member 3 -2.77409
IFNA21 interferon, alpha 21 -2.77074
IFNA4 interferon, alpha 4 -2.7694
IFNA17 interferon, alpha 17 -2.76453
IFNA16 interferon, alpha 16 -2.76453
IFNA14 interferon, alpha 14 -2.75972
IFNA7 interferon, alpha 7 -2.75972
IFNA10 interferon, alpha 10 -2.75972
IFNA22P interferon, alpha 22, pseudogene -2.75555
PSG4 pregnancy specific beta-1-glycoprotein 4 -2.75301
HCG4B HLA complex group 4B (non-protein coding) -2.75184
IFNA5 interferon, alpha 5 -2.74973
LOC284344 uncharacterized LOC284344 -2.74526
KLHL9 kelch-like family member 9 -2.74526
IFNA6 interferon, alpha 6 -2.74032
IFNA13 interferon, alpha 13 -2.73798
IFNA2 interferon, alpha 2 -2.73608
IFNA8 interferon, alpha 8 -2.73024
IFNA1 interferon, alpha 1 -2.72828
IFNE interferon, epsilon -2.72466