MKN74 Gene Set

Dataset CCLE Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description A immortal human stomach-derived cell line cell that has the characteristics: Moderately differentiated adenocarcinoma. Once they were hypodiploids. Cell growth is slow. (Cell Line Ontology, CLO_0050798)
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Genes

106 genes mutated in the MKN74 cell line from the CCLE Cell Line Gene Mutation Profiles dataset.

Symbol Name
AAK1 AP2 associated kinase 1
ADAM18 ADAM metallopeptidase domain 18
ADAM28 ADAM metallopeptidase domain 28
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADGRB3 adhesion G protein-coupled receptor B3
ADGRG4 adhesion G protein-coupled receptor G4
ADHFE1 alcohol dehydrogenase, iron containing, 1
AKAP12 A kinase (PRKA) anchor protein 12
ALPK2 alpha-kinase 2
APC adenomatous polyposis coli
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
AURKC aurora kinase C
BRD2 bromodomain containing 2
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CD40LG CD40 ligand
CHD5 chromodomain helicase DNA binding protein 5
CLK3 CDC-like kinase 3
CLTCL1 clathrin, heavy chain-like 1
COL3A1 collagen, type III, alpha 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CSF1R colony stimulating factor 1 receptor
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DGKB diacylglycerol kinase, beta 90kDa
EIF4A2 eukaryotic translation initiation factor 4A2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EP300 E1A binding protein p300
EPHA3 EPH receptor A3
EPHA6 EPH receptor A6
EPHA8 EPH receptor A8
EPHB3 EPH receptor B3
EPHB4 EPH receptor B4
ETV1 ets variant 1
FANCG Fanconi anemia, complementation group G
FGFR1OP FGFR1 oncogene partner
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FN1 fibronectin 1
GRB7 growth factor receptor-bound protein 7
GRIA3 glutamate receptor, ionotropic, AMPA 3
GUCY2C guanylate cyclase 2C
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HDAC2 histone deacetylase 2
HOXA11 homeobox A11
ILK integrin-linked kinase
INSRR insulin receptor-related receptor
ITGA10 integrin, alpha 10
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KAT6B K(lysine) acetyltransferase 6B
KLK7 kallikrein-related peptidase 7
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRP1B low density lipoprotein receptor-related protein 1B
MAMDC4 MAM domain containing 4
MAML3 mastermind-like 3 (Drosophila)
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MBIP MAP3K12 binding inhibitory protein 1
MCF2 MCF.2 cell line derived transforming sequence
MET MET proto-oncogene, receptor tyrosine kinase
MYLK myosin light chain kinase
MYLK4 myosin light chain kinase family, member 4
NAV3 neuron navigator 3
NCAM1 neural cell adhesion molecule 1
NEK3 NIMA-related kinase 3
NEK8 NIMA-related kinase 8
NF1 neurofibromin 1
NOTCH3 notch 3
NOTCH4 notch 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPR1 natriuretic peptide receptor 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRK Nik related kinase
NUMA1 nuclear mitotic apparatus protein 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAX3 paired box 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGR progesterone receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKDCC protein kinase domain containing, cytoplasmic
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPRT protein tyrosine phosphatase, receptor type, T
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RECQL4 RecQ protein-like 4
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)
SETDB1 SET domain, bifurcated 1
SNRK SNF related kinase
STIL SCL/TAL1 interrupting locus
STK31 serine/threonine kinase 31
STK38 serine/threonine kinase 38
TAOK3 TAO kinase 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLK1 tousled-like kinase 1
TLN1 talin 1
TMEM123 transmembrane protein 123
TNK2 tyrosine kinase, non-receptor, 2
TP53 tumor protein p53
TP73 tumor protein p73
TRIO trio Rho guanine nucleotide exchange factor
TRPS1 trichorhinophalangeal syndrome I
TTN titin
ULK2 unc-51 like autophagy activating kinase 2
VEGFC vascular endothelial growth factor C