MKNK1 Gene Set

Dataset PhosphoSitePlus Substrates of Kinases
Category physical interactions
Type kinase
Description MAP kinase interacting serine/threonine kinase 1|This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 8569)
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6 substrates of the kinase MKNK1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

Symbol Name
EIF4E eukaryotic translation initiation factor 4E
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PNPLA8 patatin-like phospholipase domain containing 8
SFPQ splicing factor proline/glutamine-rich
SPRY2 sprouty homolog 2 (Drosophila)