ML1 Gene Set

Dataset CCLE Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human acute myeloblastic leukaemia cell line from human peripheral blood. Morphology: Myoblast. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001884)
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Genes

734 genes with high or low expression in ML1 relative to other cell lines from the CCLE Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
C16ORF89 chromosome 16 open reading frame 89 3.40806
TG thyroglobulin 3.40803
MXRA5 matrix-remodelling associated 5 3.40802
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 3.40778
ARL9 ADP-ribosylation factor-like 9 3.17857
MRC2 mannose receptor, C type 2 2.85297
NRK Nik related kinase 2.65495
TMEM130 transmembrane protein 130 2.65492
DIO1 deiodinase, iodothyronine, type I 2.65483
SST somatostatin 2.58115
CCDC85A coiled-coil domain containing 85A 2.50898
IPO13 importin 13 2.4972
IMPAD1 inositol monophosphatase domain containing 1 2.47041
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 2.44197
FZD6 frizzled class receptor 6 2.42107
PKNOX1 PBX/knotted 1 homeobox 1 2.41751
FOXE1 forkhead box E1 2.41413
CALCB calcitonin-related polypeptide beta 2.41014
PDE1A phosphodiesterase 1A, calmodulin-dependent 2.40872
DMRT3 doublesex and mab-3 related transcription factor 3 2.40871
TPO thyroid peroxidase 2.40871
STATH statherin 2.40748
ULBP3 UL16 binding protein 3 2.35667
CA13 carbonic anhydrase XIII 2.35504
PPP1R1C protein phosphatase 1, regulatory (inhibitor) subunit 1C 2.33657
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 2.26967
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 2.25901
OTOS otospiralin 2.25089
KLHDC8A kelch domain containing 8A 2.2487
GPX3 glutathione peroxidase 3 2.22623
PDIA3 protein disulfide isomerase family A, member 3 2.21099
EPB41L5 erythrocyte membrane protein band 4.1 like 5 2.20942
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 2.20891
FZD1 frizzled class receptor 1 2.1721
ZCCHC12 zinc finger, CCHC domain containing 12 2.13763
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.13732
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.13701
PDE3A phosphodiesterase 3A, cGMP-inhibited 2.1348
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.05206
KRT27 keratin 27, type I 2.04754
EFCAB13 EF-hand calcium binding domain 13 2.03831
RDH10 retinol dehydrogenase 10 (all-trans) 2.03717
ACLY ATP citrate lyase 2.00397
PDE4D phosphodiesterase 4D, cAMP-specific 2.00059
DOCK1 dedicator of cytokinesis 1 1.98871
PCSK1 proprotein convertase subtilisin/kexin type 1 1.97765
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 1.97071
ADGRG1 adhesion G protein-coupled receptor G1 1.9659
HSPA12A heat shock 70kDa protein 12A 1.96568
PRKCZ protein kinase C, zeta 1.95691
TBL1X transducin (beta)-like 1X-linked 1.93739
ARMCX2 armadillo repeat containing, X-linked 2 1.9141
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.90521
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.89399
NMB neuromedin B 1.89243
SEC23A Sec23 homolog A (S. cerevisiae) 1.8911
CNTN6 contactin 6 1.88333
PYGM phosphorylase, glycogen, muscle 1.87431
TCTN3 tectonic family member 3 1.86737
COL14A1 collagen, type XIV, alpha 1 1.86379
CFI complement factor I 1.84971
FNDC1 fibronectin type III domain containing 1 1.84679
LINC00102 long intergenic non-protein coding RNA 102 1.83724
CFHR2 complement factor H-related 2 1.82548
ATL2 atlastin GTPase 2 1.82297
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.81894
INAFM1 InaF-motif containing 1 1.81861
TMEM167A transmembrane protein 167A 1.80833
CFH complement factor H 1.79469
ZNF436 zinc finger protein 436 1.78914
NKX2-1 NK2 homeobox 1 1.77237
PAPD5 PAP associated domain containing 5 1.76992
IL1R1 interleukin 1 receptor, type I 1.7485
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.74138
TOX4 TOX high mobility group box family member 4 1.73513
SAR1A secretion associated, Ras related GTPase 1A 1.73392
THBS3 thrombospondin 3 1.72484
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 1.72139
GGT5 gamma-glutamyltransferase 5 1.71208
SLC14A2 solute carrier family 14 (urea transporter), member 2 1.71041
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 1.70573
CASC4 cancer susceptibility candidate 4 1.70261
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.69009
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 1.68511
MBIP MAP3K12 binding inhibitory protein 1 1.68355
PRDM16 PR domain containing 16 1.68038
SERTM1 serine-rich and transmembrane domain containing 1 1.67761
ARMCX3 armadillo repeat containing, X-linked 3 1.67296
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.66862
CRLF1 cytokine receptor-like factor 1 1.66096
SPHAR S-phase response (cyclin related) 1.65149
LOC100131691 1.64694
FAM13C family with sequence similarity 13, member C 1.63997
HTN3 histatin 3 1.63718
PORCN porcupine homolog (Drosophila) 1.63457
LONRF2 LON peptidase N-terminal domain and ring finger 2 1.63407
UBE4B ubiquitination factor E4B 1.63022
ITFG1 integrin alpha FG-GAP repeat containing 1 1.62687
TMEM100 transmembrane protein 100 1.62647
TRAM1 translocation associated membrane protein 1 1.62603
SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.626
LRP12 low density lipoprotein receptor-related protein 12 1.62547
PLD3 phospholipase D family, member 3 1.61637
ITGAV integrin, alpha V 1.61395
MXRA8 matrix-remodelling associated 8 1.60253
TSPAN18 tetraspanin 18 1.60034
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 1.59811
DAD1 defender against cell death 1 1.59646
DAPL1 death associated protein-like 1 1.59358
IDO2 indoleamine 2,3-dioxygenase 2 1.59193
TSC2 tuberous sclerosis 2 1.59064
NPW neuropeptide W 1.59019
TM9SF1 transmembrane 9 superfamily member 1 1.58426
SFRP1 secreted frizzled-related protein 1 1.58361
HBEGF heparin-binding EGF-like growth factor 1.58268
SLIT3 slit homolog 3 (Drosophila) 1.57898
TMEM165 transmembrane protein 165 1.57637
USP8 ubiquitin specific peptidase 8 1.57326
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 1.57142
P4HB prolyl 4-hydroxylase, beta polypeptide 1.56973
TSPYL5 TSPY-like 5 1.56838
IDO1 indoleamine 2,3-dioxygenase 1 1.56434
KRT86 keratin 86, type II 1.56011
RANBP17 RAN binding protein 17 1.55959
SFTA3 surfactant associated 3 1.55583
PRAF2 PRA1 domain family, member 2 1.55573
OASL 2'-5'-oligoadenylate synthetase-like 1.55016
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 1.54948
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 1.54232
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.5394
RHOBTB3 Rho-related BTB domain containing 3 1.5377
CA11 carbonic anhydrase XI 1.53367
CRELD2 cysteine-rich with EGF-like domains 2 1.53256
DCSTAMP dendrocyte expressed seven transmembrane protein 1.53121
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 1.52988
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 1.52889
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 1.52467
TMED2 transmembrane emp24 domain trafficking protein 2 1.52304
DLX2 distal-less homeobox 2 1.52197
SHE Src homology 2 domain containing E 1.51846
PPP1R3B protein phosphatase 1, regulatory subunit 3B 1.51315
TMEM169 transmembrane protein 169 1.50971
P3H1 prolyl 3-hydroxylase 1 1.50536
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene 1.50501
RUFY2 RUN and FYVE domain containing 2 1.5002
CGNL1 cingulin-like 1 1.49911
GAA glucosidase, alpha; acid 1.49787
SORBS2 sorbin and SH3 domain containing 2 1.49572
SNCG synuclein, gamma (breast cancer-specific protein 1) 1.49229
TREM1 triggering receptor expressed on myeloid cells 1 1.49055
TMEM59 transmembrane protein 59 1.4903
BFSP1 beaded filament structural protein 1, filensin 1.48991
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 1.48887
MMRN2 multimerin 2 1.48754
CNTN5 contactin 5 1.48575
RASD2 RASD family, member 2 1.48569
AFAP1L2 actin filament associated protein 1-like 2 1.48018
MIR143HG MIR143 host gene 1.47974
IGFBP4 insulin-like growth factor binding protein 4 1.47922
INSC inscuteable homolog (Drosophila) 1.47193
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.47135
ZNF365 zinc finger protein 365 1.47037
NELL2 NEL-like 2 (chicken) 1.46742
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 1.46689
ZYG11B zyg-11 family member B, cell cycle regulator 1.46169
PARD6B par-6 family cell polarity regulator beta 1.46162
PTPRE protein tyrosine phosphatase, receptor type, E 1.45945
RAB11FIP2 RAB11 family interacting protein 2 (class I) 1.45748
SHISA6 shisa family member 6 1.45377
AFF4 AF4/FMR2 family, member 4 1.45346
SIK1 salt-inducible kinase 1 1.45258
SALL2 spalt-like transcription factor 2 1.44394
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 1.44339
CLIC2 chloride intracellular channel 2 1.44178
KLHDC2 kelch domain containing 2 1.44141
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 1.43998
HIBADH 3-hydroxyisobutyrate dehydrogenase 1.4346
FAM189A2 family with sequence similarity 189, member A2 1.43024
XKR4 XK, Kell blood group complex subunit-related family, member 4 1.4227
LIX1 Lix1 homolog (chicken) 1.41324
PDGFRL platelet-derived growth factor receptor-like 1.40905
STRN3 striatin, calmodulin binding protein 3 1.40898
FAM196A family with sequence similarity 196, member A 1.4083
KPNA6 karyopherin alpha 6 (importin alpha 7) 1.40316
DGKI diacylglycerol kinase, iota 1.40299
HEXA hexosaminidase A (alpha polypeptide) 1.40191
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2 1.39937
IGFBP5 insulin-like growth factor binding protein 5 1.39672
KERA keratocan 1.39615
RHOB ras homolog family member B 1.3923
TAS2R10 taste receptor, type 2, member 10 1.39079
SLC44A5 solute carrier family 44, member 5 1.39064
PAM peptidylglycine alpha-amidating monooxygenase 1.38854
NEMF nuclear export mediator factor 1.38815
ACSM5 acyl-CoA synthetase medium-chain family member 5 1.38763
SULF1 sulfatase 1 1.38356
CLCN4 chloride channel, voltage-sensitive 4 1.3824
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 1.38217
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 1.38206
STON1 stonin 1 1.38203
SLC26A2 solute carrier family 26 (anion exchanger), member 2 1.38139
SNAI1 snail family zinc finger 1 1.38107
ALDOA aldolase A, fructose-bisphosphate 1.3806
FRZB frizzled-related protein 1.38039
RAB36 RAB36, member RAS oncogene family 1.37941
CHM choroideremia (Rab escort protein 1) 1.3773
SCARB2 scavenger receptor class B, member 2 1.37652
SEC23IP SEC23 interacting protein 1.37615
LRP5L low density lipoprotein receptor-related protein 5-like 1.37553
SLC30A5 solute carrier family 30 (zinc transporter), member 5 1.37496
ADAM10 ADAM metallopeptidase domain 10 1.37447
FAM49A family with sequence similarity 49, member A 1.37254
TMEM144 transmembrane protein 144 1.37028
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 1.3662
C8ORF31 chromosome 8 open reading frame 31 1.36184
TSPAN12 tetraspanin 12 1.35596
OSTC oligosaccharyltransferase complex subunit (non-catalytic) 1.35225
PTPRJ protein tyrosine phosphatase, receptor type, J 1.34904

low expression

Symbol Name Standardized Value
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 -3.9697
PLAC9 placenta-specific 9 -3.30303
PHGR1 proline/histidine/glycine-rich 1 -3.18345
TADA2A transcriptional adaptor 2A -3.16116
LINC00299 long intergenic non-protein coding RNA 299 -3.13339
CHAD chondroadherin -3.12097
SPICE1 spindle and centriole associated protein 1 -3.11235
SP6 Sp6 transcription factor -3.05389
RAB40A RAB40A, member RAS oncogene family -3.03869
CALCR calcitonin receptor -2.95843
NME9 NME/NM23 family member 9 -2.93155
KRT9 keratin 9, type I -2.9254
RHCG Rh family, C glycoprotein -2.87366
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -2.7966
IFI27L1 interferon, alpha-inducible protein 27-like 1 -2.79256
C8ORF74 chromosome 8 open reading frame 74 -2.76755
C6ORF25 chromosome 6 open reading frame 25 -2.74332
LOR loricrin -2.72749
TACR3 tachykinin receptor 3 -2.72295
MIR497HG mir-497-195 cluster host gene -2.70845
PSORS1C1 psoriasis susceptibility 1 candidate 1 -2.70509
AGRP agouti related neuropeptide -2.69982
DCD dermcidin -2.64543
A2ML1 alpha-2-macroglobulin-like 1 -2.64255
ZMYND10 zinc finger, MYND-type containing 10 -2.63312
PRDM12 PR domain containing 12 -2.62605
SPRR3 small proline-rich protein 3 -2.61686
CACTIN cactin, spliceosome C complex subunit -2.59504
APOM apolipoprotein M -2.59421
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.58706
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 -2.57139
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 -2.57088
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -2.56881
TNR tenascin R -2.56525
C6ORF136 chromosome 6 open reading frame 136 -2.53912
NOXO1 NADPH oxidase organizer 1 -2.53146
LRRC25 leucine rich repeat containing 25 -2.52639
GPR21 G protein-coupled receptor 21 -2.50216
SNTG1 syntrophin, gamma 1 -2.49507
MRPL14 mitochondrial ribosomal protein L14 -2.49253
WDR93 WD repeat domain 93 -2.47624
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -2.47576
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 -2.47548
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 -2.46854
MRPS22 mitochondrial ribosomal protein S22 -2.46789
USP2 ubiquitin specific peptidase 2 -2.46321
LOC284395 uncharacterized LOC284395 -2.44768
ZAR1 zygote arrest 1 -2.44426
FGL2 fibrinogen-like 2 -2.40416
LOC100505918 uncharacterized LOC100505918 -2.39197
KAT5 K(lysine) acetyltransferase 5 -2.3788
SYCE3 synaptonemal complex central element protein 3 -2.37246
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -2.36142
ITPK1 inositol-tetrakisphosphate 1-kinase -2.34998
SNAP91 synaptosomal-associated protein, 91kDa -2.34942
PNPLA5 patatin-like phospholipase domain containing 5 -2.34916
XGY2 Xg pseudogene, Y-linked 2 -2.34572
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -2.3396
TLR10 toll-like receptor 10 -2.33692
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 -2.31646
CHRD chordin -2.31628
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 -2.31371
CNTFR ciliary neurotrophic factor receptor -2.31266
CST6 cystatin E/M -2.3122
LAMA3 laminin, alpha 3 -2.30809
TMPRSS13 transmembrane protease, serine 13 -2.30709
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.28256
ECRP ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) pseudogene -2.28014
MRPL48 mitochondrial ribosomal protein L48 -2.27082
LINC00593 long intergenic non-protein coding RNA 593 -2.26824
PRDM11 PR domain containing 11 -2.25306
ASCL2 achaete-scute family bHLH transcription factor 2 -2.25056
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 -2.24879
PMCHL2 pro-melanin-concentrating hormone-like 2, pseudogene -2.21923
AQP10 aquaporin 10 -2.21722
WIZ widely interspaced zinc finger motifs -2.21485
COQ3 coenzyme Q3 methyltransferase -2.20855
CCKAR cholecystokinin A receptor -2.20578
DHPS deoxyhypusine synthase -2.20445
TUBB1 tubulin, beta 1 class VI -2.18164
LOC151174 uncharacterized LOC151174 -2.17017
LOC100133461 uncharacterized LOC100133461 -2.1692
CYSRT1 cysteine-rich tail protein 1 -2.16049
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) -2.15688
FANCE Fanconi anemia, complementation group E -2.15648
APCS amyloid P component, serum -2.15048
MAGEB1 melanoma antigen family B1 -2.13781
DCHS1 dachsous cadherin-related 1 -2.13655
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator -2.13323
C22ORF42 chromosome 22 open reading frame 42 -2.13293
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding) -2.13107
PNLIPRP2 pancreatic lipase-related protein 2 -2.12978
KRT1 keratin 1, type II -2.1296
PRR34 proline rich 34 -2.12795
GMIP GEM interacting protein -2.12378
DOT1L DOT1-like histone H3K79 methyltransferase -2.11473
RABL6 RAB, member RAS oncogene family-like 6 -2.11158
CCDC177 coiled-coil domain containing 177 -2.10891
ONECUT3 one cut homeobox 3 -2.10722
ZNF341 zinc finger protein 341 -2.10377
SLC35G3 solute carrier family 35, member G3 -2.10092
KRT84 keratin 84, type II -2.10076
CDHR1 cadherin-related family member 1 -2.09892
C6ORF201 chromosome 6 open reading frame 201 -2.09286
NOVA2 neuro-oncological ventral antigen 2 -2.09073
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -2.08713
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 -2.08609
CCL17 chemokine (C-C motif) ligand 17 -2.07979
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 -2.07696
MEA1 male-enhanced antigen 1 -2.07019
SIGLEC8 sialic acid binding Ig-like lectin 8 -2.06984
TPRN taperin -2.0644
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 -2.06214
VSX1 visual system homeobox 1 -2.05399
ALPI alkaline phosphatase, intestinal -2.04628
CDCA7L cell division cycle associated 7-like -2.04619
LSP1 lymphocyte-specific protein 1 -2.04553
AQP7 aquaporin 7 -2.02887
APOC3 apolipoprotein C-III -2.02624
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.02227
ZSCAN20 zinc finger and SCAN domain containing 20 -2.02097
SPI1 Spi-1 proto-oncogene -2.01866
RAD23A RAD23 homolog A (S. cerevisiae) -2.01788
NEFM neurofilament, medium polypeptide -2.01728
TSNARE1 t-SNARE domain containing 1 -2.01226
SSTR4 somatostatin receptor 4 -2.00826
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -2.00753
MUC13 mucin 13, cell surface associated -2.00617
MASP2 mannan-binding lectin serine peptidase 2 -2.00399
LOC100130357 uncharacterized LOC100130357 -2.00355
NOL7 nucleolar protein 7, 27kDa -1.99908
LOC389332 uncharacterized LOC389332 -1.99783
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 -1.9787
GPRIN2 G protein regulated inducer of neurite outgrowth 2 -1.97865
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -1.97795
MYO19 myosin XIX -1.97209
GUCY2F guanylate cyclase 2F, retinal -1.97135
SSTR3 somatostatin receptor 3 -1.97134
HPCA hippocalcin -1.97134
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.9705
TSSK6 testis-specific serine kinase 6 -1.96843
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -1.96771
FCRL3 Fc receptor-like 3 -1.96742
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 -1.96639
LOC284661 uncharacterized LOC284661 -1.96484
AARS2 alanyl-tRNA synthetase 2, mitochondrial -1.95846
TEX101 testis expressed 101 -1.95504
LRRC55 leucine rich repeat containing 55 -1.95246
LOC284865 uncharacterized LOC284865 -1.95128
TDP1 tyrosyl-DNA phosphodiesterase 1 -1.95125
NELFE negative elongation factor complex member E -1.94609
NYAP1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 -1.94529
ZDHHC19 zinc finger, DHHC-type containing 19 -1.94494
FAM132A family with sequence similarity 132, member A -1.94463
LMX1A LIM homeobox transcription factor 1, alpha -1.94448
PCP2 Purkinje cell protein 2 -1.94393
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 -1.9432
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -1.94021
PRRC2A proline-rich coiled-coil 2A -1.93979
CASS4 Cas scaffolding protein family member 4 -1.93694
GZMK granzyme K (granzyme 3; tryptase II) -1.93636
IGHMBP2 immunoglobulin mu binding protein 2 -1.93273
EOMES eomesodermin -1.92968
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -1.92911
HCK HCK proto-oncogene, Src family tyrosine kinase -1.92832
ADAM21 ADAM metallopeptidase domain 21 -1.92722
FSCB fibrous sheath CABYR binding protein -1.92241
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 -1.92198
RAD9A RAD9 homolog A (S. pombe) -1.91857
CHRND cholinergic receptor, nicotinic, delta (muscle) -1.91776
CCDC37 coiled-coil domain containing 37 -1.91745
PRODH2 proline dehydrogenase (oxidase) 2 -1.91662
ESPNL espin-like -1.91642
RASL10A RAS-like, family 10, member A -1.91448
SMYD1 SET and MYND domain containing 1 -1.91371
PROZ protein Z, vitamin K-dependent plasma glycoprotein -1.90766
TM4SF5 transmembrane 4 L six family member 5 -1.90224
LPPR1 lipid phosphate phosphatase-related protein type 1 -1.90158
AA06 uncharacterized LOC100506677 -1.89966
DXO decapping exoribonuclease -1.89593
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -1.89246
PRSS22 protease, serine, 22 -1.88871
CSH2 chorionic somatomammotropin hormone 2 -1.88862
LINC00163 long intergenic non-protein coding RNA 163 -1.88115
BRD4 bromodomain containing 4 -1.87875
LMOD2 leiomodin 2 (cardiac) -1.87744
UMPS uridine monophosphate synthetase -1.87722
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -1.87636
SPDEF SAM pointed domain containing ETS transcription factor -1.87408
UQCC3 ubiquinol-cytochrome c reductase complex assembly factor 3 -1.86874
PNMAL2 paraneoplastic Ma antigen family-like 2 -1.86872
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) -1.86636
EDDM3B epididymal protein 3B -1.86614
C10ORF67 chromosome 10 open reading frame 67 -1.86586
FBXL19-AS1 FBXL19 antisense RNA 1 (head to head) -1.86327
TRMT10C tRNA methyltransferase 10 homolog C (S. cerevisiae) -1.85949
LOC283177 uncharacterized LOC283177 -1.85239
ADAM20 ADAM metallopeptidase domain 20 -1.85195
TMIGD2 transmembrane and immunoglobulin domain containing 2 -1.84881
TRIM10 tripartite motif containing 10 -1.8448
CLP1 cleavage and polyadenylation factor I subunit 1 -1.84384
PTPN23 protein tyrosine phosphatase, non-receptor type 23 -1.8426
SNW1 SNW domain containing 1 -1.84217
CCT8 chaperonin containing TCP1, subunit 8 (theta) -1.84185
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -1.84061
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -1.83943
UCN3 urocortin 3 -1.83704
CASP5 caspase 5, apoptosis-related cysteine peptidase -1.83696
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 -1.83515
VTCN1 V-set domain containing T cell activation inhibitor 1 -1.83409
KIAA1161 KIAA1161 -1.83197
DDB2 damage-specific DNA binding protein 2, 48kDa -1.83084
LINC00282 long intergenic non-protein coding RNA 282 -1.83031
ASPRV1 aspartic peptidase, retroviral-like 1 -1.82701
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 -1.82387
CCDC105 coiled-coil domain containing 105 -1.82345
C9ORF84 chromosome 9 open reading frame 84 -1.82189
OARD1 O-acyl-ADP-ribose deacylase 1 -1.82036
EPHX3 epoxide hydrolase 3 -1.82035
XIRP2 xin actin binding repeat containing 2 -1.81863
PRPF19 pre-mRNA processing factor 19 -1.81626
VMO1 vitelline membrane outer layer 1 homolog (chicken) -1.81471
REPS1 RALBP1 associated Eps domain containing 1 -1.81353
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -1.81231
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3 -1.8116
INTS4 integrator complex subunit 4 -1.80884
CTSG cathepsin G -1.80787
MEP1A meprin A, alpha (PABA peptide hydrolase) -1.80765
C1ORF127 chromosome 1 open reading frame 127 -1.80492
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8 -1.80247
MCEMP1 mast cell-expressed membrane protein 1 -1.80158
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 -1.80039
CCDC94 coiled-coil domain containing 94 -1.79752
MYO15A myosin XVA -1.79538
C11ORF48 -1.79418
PPAN peter pan homolog (Drosophila) -1.792
PEX16 peroxisomal biogenesis factor 16 -1.79084
MED19 mediator complex subunit 19 -1.78871
SPINK1 serine peptidase inhibitor, Kazal type 1 -1.78722
CRYBB1 crystallin, beta B1 -1.78707
FKBPL FK506 binding protein like -1.7849
ANAPC15 anaphase promoting complex subunit 15 -1.78379
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -1.7783
ODF3L2 outer dense fiber of sperm tails 3-like 2 -1.7772
PTCH2 patched 2 -1.77519
IL36RN interleukin 36 receptor antagonist -1.77312
ESR1 estrogen receptor 1 -1.77128
CELA2A chymotrypsin-like elastase family, member 2A -1.77125
BPIFA1 BPI fold containing family A, member 1 -1.76745
ALDOC aldolase C, fructose-bisphosphate -1.7647
FPR2 formyl peptide receptor 2 -1.76342
RNASEH2C ribonuclease H2, subunit C -1.76331
SF3B2 splicing factor 3b, subunit 2, 145kDa -1.76279
FLJ32955 -1.76243
CRLF3 cytokine receptor-like factor 3 -1.76222
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 -1.76186
LKAAEAR1 LKAAEAR motif containing 1 -1.76179
RNF183 ring finger protein 183 -1.7591
C1ORF21 chromosome 1 open reading frame 21 -1.75895
VWA3A von Willebrand factor A domain containing 3A -1.75801
ASB2 ankyrin repeat and SOCS box containing 2 -1.75768
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 -1.75737
SCN5A sodium channel, voltage gated, type V alpha subunit -1.75662
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -1.75435
SMCO3 single-pass membrane protein with coiled-coil domains 3 -1.75342
ADH6 alcohol dehydrogenase 6 (class V) -1.75284
NKD1 naked cuticle homolog 1 (Drosophila) -1.7526
ZNF366 zinc finger protein 366 -1.75131
DPPA2 developmental pluripotency associated 2 -1.75073
C14ORF105 chromosome 14 open reading frame 105 -1.75015
ADGRL3 adhesion G protein-coupled receptor L3 -1.74536
SART1 squamous cell carcinoma antigen recognized by T cells -1.74524
LOC100507642 uncharacterized LOC100507642 -1.74488
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) -1.74272
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 -1.7419
LOC100130100 Ig kappa chain V-I region Walker-like -1.73943
MAD2L1BP MAD2L1 binding protein -1.7385
CEP63 centrosomal protein 63kDa -1.73603
SIM1 single-minded family bHLH transcription factor 1 -1.73361
LOC731424 uncharacterized LOC731424 -1.73294
SLC16A11 solute carrier family 16, member 11 -1.73073
INTS5 integrator complex subunit 5 -1.72879
SHCBP1L SHC SH2-domain binding protein 1-like -1.72627
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -1.72518
ARMC12 armadillo repeat containing 12 -1.72505
TTC9C tetratricopeptide repeat domain 9C -1.72332
SLC5A11 solute carrier family 5 (sodium/inositol cotransporter), member 11 -1.72233
UPK1B uroplakin 1B -1.72099
ZBTB3 zinc finger and BTB domain containing 3 -1.71964
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific -1.71919
LOC100506558 -1.71881
C11ORF44 chromosome 11 open reading frame 44 -1.7181
GUCY2C guanylate cyclase 2C -1.71124
DAXX death-domain associated protein -1.70814
C1QA complement component 1, q subcomponent, A chain -1.70644
GPR26 G protein-coupled receptor 26 -1.70632
MSC musculin -1.70466
HAPLN2 hyaluronan and proteoglycan link protein 2 -1.70292
OR2C3 olfactory receptor, family 2, subfamily C, member 3 -1.7006
TCTEX1D1 Tctex1 domain containing 1 -1.70011
REG1A regenerating islet-derived 1 alpha -1.69932
SMTNL2 smoothelin-like 2 -1.69841
TPPP2 tubulin polymerization-promoting protein family member 2 -1.69817
UMODL1-AS1 UMODL1 antisense RNA 1 -1.69688
IFNA5 interferon, alpha 5 -1.69488
HMBS hydroxymethylbilane synthase -1.69317
CR1L complement component (3b/4b) receptor 1-like -1.6922
DIO3OS DIO3 opposite strand/antisense RNA (head to head) -1.69219
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -1.69213
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -1.69029
LY6G6C lymphocyte antigen 6 complex, locus G6C -1.68749
COL11A2 collagen, type XI, alpha 2 -1.68736
GPR31 G protein-coupled receptor 31 -1.68522
RDH16 retinol dehydrogenase 16 (all-trans) -1.68502
SOGA3 SOGA family member 3 -1.68427
SP5 Sp5 transcription factor -1.67832
ACAN aggrecan -1.6754
LOC340357 uncharacterized LOC340357 -1.67475
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -1.67328
KLK5 kallikrein-related peptidase 5 -1.67283
IGSF6 immunoglobulin superfamily, member 6 -1.66961
TTLL4 tubulin tyrosine ligase-like family member 4 -1.66541
MRPS18A mitochondrial ribosomal protein S18A -1.66144
FANCG Fanconi anemia, complementation group G -1.65972
RHO rhodopsin -1.65322
DCC DCC netrin 1 receptor -1.65291
PPBPP2 pro-platelet basic protein pseudogene 2 -1.65273
NKG7 natural killer cell granule protein 7 -1.65229
PPP1R17 protein phosphatase 1, regulatory subunit 17 -1.6511
TOPBP1 topoisomerase (DNA) II binding protein 1 -1.65058
CDH23 cadherin-related 23 -1.64924
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -1.64506
MRPS18B mitochondrial ribosomal protein S18B -1.64403
BPIFA3 BPI fold containing family A, member 3 -1.64362
KIFC1 kinesin family member C1 -1.64279
RNF186 ring finger protein 186 -1.64219
MMP15 matrix metallopeptidase 15 (membrane-inserted) -1.64151
RAD18 RAD18 E3 ubiquitin protein ligase -1.64145
HAO2 hydroxyacid oxidase 2 (long chain) -1.63848
TRMT61A tRNA methyltransferase 61A -1.63747
PTH2 parathyroid hormone 2 -1.63629
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -1.63471
IL18BP interleukin 18 binding protein -1.63445
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -1.63186
TSPAN32 tetraspanin 32 -1.63152
PWRN1 Prader-Willi region non-protein coding RNA 1 -1.62905
NELFB negative elongation factor complex member B -1.62875
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.62621
CUL9 cullin 9 -1.62382
DRD5 dopamine receptor D5 -1.6236
PLA2G4F phospholipase A2, group IVF -1.62279
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 -1.61893
EXOSC8 exosome component 8 -1.61832
CHRM2 cholinergic receptor, muscarinic 2 -1.61421
NYX nyctalopin -1.61331
PDCD1 programmed cell death 1 -1.61291
CEP250 centrosomal protein 250kDa -1.60952
NDOR1 NADPH dependent diflavin oxidoreductase 1 -1.60688
SNRPC small nuclear ribonucleoprotein polypeptide C -1.60668
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -1.60635
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 -1.60403
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein -1.60237
C19ORF52 chromosome 19 open reading frame 52 -1.60128
CXCL14 chemokine (C-X-C motif) ligand 14 -1.59998
ANKFN1 ankyrin-repeat and fibronectin type III domain containing 1 -1.5994
DNAH3 dynein, axonemal, heavy chain 3 -1.5981
TRAIP TRAF interacting protein -1.59741
ESX1 ESX homeobox 1 -1.59679
ACTN3 actinin, alpha 3 (gene/pseudogene) -1.59608
WFDC11 WAP four-disulfide core domain 11 -1.59267
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) -1.59151
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O -1.59114
KXD1 KxDL motif containing 1 -1.58858
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 -1.58822
GSTZ1 glutathione S-transferase zeta 1 -1.5881
ZNHIT3 zinc finger, HIT-type containing 3 -1.5845
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) -1.58395
ZSCAN12 zinc finger and SCAN domain containing 12 -1.58367
LOC100505938 uncharacterized LOC100505938 -1.58327
FERMT3 fermitin family member 3 -1.58244
GEMIN4 gem (nuclear organelle) associated protein 4 -1.58047
CASR calcium-sensing receptor -1.57977
SYT9 synaptotagmin IX -1.57868
SLC38A11 solute carrier family 38, member 11 -1.57818
C14ORF166 chromosome 14 open reading frame 166 -1.57581
FFAR4 free fatty acid receptor 4 -1.57429
ZNF408 zinc finger protein 408 -1.574
RPA1 replication protein A1, 70kDa -1.57381
LOC100130264 uncharacterized LOC100130264 -1.57312
OSM oncostatin M -1.57242
RGMA repulsive guidance molecule family member a -1.57161
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -1.57036
F11 coagulation factor XI -1.5679
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -1.56767
FAM185A family with sequence similarity 185, member A -1.56682
VSIG2 V-set and immunoglobulin domain containing 2 -1.56273
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -1.56238
PCCB propionyl CoA carboxylase, beta polypeptide -1.56145
GCDH glutaryl-CoA dehydrogenase -1.56143
TRAF3 TNF receptor-associated factor 3 -1.56058
LOC286114 uncharacterized LOC286114 -1.55934
PON1 paraoxonase 1 -1.55731
NIT2 nitrilase family, member 2 -1.55598
LYPD3 LY6/PLAUR domain containing 3 -1.55495
ANKRD53 ankyrin repeat domain 53 -1.55454
MYH7B myosin, heavy chain 7B, cardiac muscle, beta -1.55064
DNTT DNA nucleotidylexotransferase -1.55026
ATG3 autophagy related 3 -1.54996
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa -1.54874
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 -1.5474
MRPL3 mitochondrial ribosomal protein L3 -1.54638
C21ORF2 chromosome 21 open reading frame 2 -1.54623
C9ORF9 chromosome 9 open reading frame 9 -1.54556
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 -1.54448
RLN1 relaxin 1 -1.54406
C1ORF87 chromosome 1 open reading frame 87 -1.54367
KLK1 kallikrein 1 -1.54349
MRPL18 mitochondrial ribosomal protein L18 -1.54235
FRAS1 Fraser extracellular matrix complex subunit 1 -1.54229
C14ORF80 chromosome 14 open reading frame 80 -1.5393
TRIM26 tripartite motif containing 26 -1.53832
TTC31 tetratricopeptide repeat domain 31 -1.53823
PCYT1B phosphate cytidylyltransferase 1, choline, beta -1.53636
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 -1.53529
NTNG1 netrin G1 -1.53507
IGHV1-2 immunoglobulin heavy variable 1-2 -1.53374
CWC15 CWC15 spliceosome-associated protein -1.53373
TMOD4 tropomodulin 4 (muscle) -1.53331
GPR37L1 G protein-coupled receptor 37 like 1 -1.53227
ALX3 ALX homeobox 3 -1.53211
TDP2 tyrosyl-DNA phosphodiesterase 2 -1.52973
POC1A POC1 centriolar protein A -1.52925
MFAP5 microfibrillar associated protein 5 -1.52898
HMGA1 high mobility group AT-hook 1 -1.52853
LENEP lens epithelial protein -1.52845
SFMBT1 Scm-like with four mbt domains 1 -1.52717
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 -1.52714
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -1.52654
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) -1.52436
TJAP1 tight junction associated protein 1 (peripheral) -1.52435
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) -1.52365
ZMYND19 zinc finger, MYND-type containing 19 -1.52268
PIFO primary cilia formation -1.52154
CNTROB centrobin, centrosomal BRCA2 interacting protein -1.5204
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -1.51969
MC3R melanocortin 3 receptor -1.5171
ZNF653 zinc finger protein 653 -1.51679
TACR2 tachykinin receptor 2 -1.51654
LINC00523 long intergenic non-protein coding RNA 523 -1.51542
CATSPER3 cation channel, sperm associated 3 -1.51522
SPATA24 spermatogenesis associated 24 -1.51244
MTMR14 myotubularin related protein 14 -1.51209
CAPS calcyphosine -1.51203
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -1.51149
ACYP1 acylphosphatase 1, erythrocyte (common) type -1.51126
PLA2G2E phospholipase A2, group IIE -1.51095
ACHE acetylcholinesterase (Yt blood group) -1.51069
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon -1.50975
OR3A3 olfactory receptor, family 3, subfamily A, member 3 -1.50948
CALML5 calmodulin-like 5 -1.50932
FHDC1 FH2 domain containing 1 -1.50906
SPHKAP SPHK1 interactor, AKAP domain containing -1.50691
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -1.50341
TRAF3IP2-AS1 TRAF3IP2 antisense RNA 1 -1.50329
MEN1 multiple endocrine neoplasia I -1.5031
ABCA17P ATP-binding cassette, sub-family A (ABC1), member 17, pseudogene -1.50103
ATOH1 atonal homolog 1 (Drosophila) -1.5003
CARD14 caspase recruitment domain family, member 14 -1.49918
TRIM51 tripartite motif-containing 51 -1.49898
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -1.49869
ASIC3 acid sensing (proton gated) ion channel 3 -1.49808
C15ORF62 chromosome 15 open reading frame 62 -1.49776
TSPYL6 TSPY-like 6 -1.49771
PIRT phosphoinositide-interacting regulator of transient receptor potential channels -1.49639
SLURP1 secreted LY6/PLAUR domain containing 1 -1.49437
RABL3 RAB, member of RAS oncogene family-like 3 -1.49325
CYMP chymosin pseudogene -1.49308
LOC100506571 uncharacterized LOC100506571 -1.49294
MPO myeloperoxidase -1.49069
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -1.48824
C1ORF110 chromosome 1 open reading frame 110 -1.48687
WBSCR27 Williams Beuren syndrome chromosome region 27 -1.48545
PQLC2L PQ loop repeat containing 2-like -1.48527
ABT1 activator of basal transcription 1 -1.48448
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 -1.48354
AICDA activation-induced cytidine deaminase -1.48324
GMEB2 glucocorticoid modulatory element binding protein 2 -1.48215
LOC100130331 POTE ankyrin domain family, member F pseudogene -1.48048
WIPF3 WAS/WASL interacting protein family, member 3 -1.48037
ADRA1D adrenoceptor alpha 1D -1.48017
GSK3A glycogen synthase kinase 3 alpha -1.4801
SCAF1 SR-related CTD-associated factor 1 -1.47782
C11ORF31 chromosome 11 open reading frame 31 -1.47758
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -1.47681
SP7 Sp7 transcription factor -1.47611
KCNK16 potassium channel, two pore domain subfamily K, member 16 -1.47572
PTCHD2 patched domain containing 2 -1.47321
FBXO24 F-box protein 24 -1.47215
GYLTL1B glycosyltransferase-like 1B -1.47182
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -1.46992
OR10H1 olfactory receptor, family 10, subfamily H, member 1 -1.46712
SH2D5 SH2 domain containing 5 -1.46586
CNTD2 cyclin N-terminal domain containing 2 -1.46423
VARS2 valyl-tRNA synthetase 2, mitochondrial -1.46077
FAM170A family with sequence similarity 170, member A -1.46016
MRPL49 mitochondrial ribosomal protein L49 -1.45952
TRAPPC4 trafficking protein particle complex 4 -1.45921
ORAOV1 oral cancer overexpressed 1 -1.45852
NTN1 netrin 1 -1.45796
FAM160A2 family with sequence similarity 160, member A2 -1.45691
C18ORF8 chromosome 18 open reading frame 8 -1.4557
TRHR thyrotropin-releasing hormone receptor -1.45514
TBC1D21 TBC1 domain family, member 21 -1.45494
TCP1 t-complex 1 -1.45406
ASB10 ankyrin repeat and SOCS box containing 10 -1.45153
HSPB2 heat shock 27kDa protein 2 -1.45126