| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.220159 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.160498 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.103549 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.103378 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102867 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0958356 |
| CANX | calnexin | 0.0881231 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0871576 |
| CALR | calreticulin | 0.0843675 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.084048 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0786466 |
| SQSTM1 | sequestosome 1 | 0.0754921 |
| AHNAK | AHNAK nucleoprotein | 0.0746703 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0738434 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0660323 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0657281 |
| ANXA2 | annexin A2 | 0.0649413 |
| CDH13 | cadherin 13 | 0.0623783 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0621722 |
| FSTL1 | follistatin-like 1 | 0.0607166 |
| CD44 | CD44 molecule (Indian blood group) | 0.0594639 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0590049 |
| DST | dystonin | 0.0550048 |
| SEPTIN9 | septin 9 | 0.054305 |
| COL3A1 | collagen, type III, alpha 1 | 0.0534666 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0511038 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0509259 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0505948 |
| NAV2 | neuron navigator 2 | 0.0503695 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0497997 |
| TPM4 | tropomyosin 4 | 0.0490733 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0466169 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.046361 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0459241 |
| OGA | O-GlcNAcase | 0.0451468 |
| TPM3 | tropomyosin 3 | 0.0443004 |
| PTMA | prothymosin, alpha | 0.0442687 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0442614 |
| ENO1 | enolase 1, (alpha) | 0.0437035 |
| FLNB | filamin B, beta | 0.0436354 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0414925 |
| FAM107B | family with sequence similarity 107, member B | 0.0413352 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.040735 |
| APP | amyloid beta (A4) precursor protein | 0.0405448 |
| HDAC9 | histone deacetylase 9 | 0.0403849 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0396767 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0392772 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0378222 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0360939 |
| MYOF | myoferlin | 0.0352107 |
| FLNA | filamin A, alpha | 0.0345735 |
| CD109 | CD109 molecule | 0.0345259 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0345084 |
| ASPH | aspartate beta-hydroxylase | 0.0342385 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0341683 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0338267 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0334679 |
| HELZ | helicase with zinc finger | 0.0329966 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0328174 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.032598 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0325302 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0319947 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0319542 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0317693 |
| RTN4 | reticulon 4 | 0.0317675 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0317026 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0311589 |
| ERBIN | erbb2 interacting protein | 0.0308592 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0308352 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0301993 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0301759 |
| SPAG9 | sperm associated antigen 9 | 0.0300142 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0298448 |
| DSPP | dentin sialophosphoprotein | 0.0296999 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0295749 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0291576 |
| RND3 | Rho family GTPase 3 | 0.0290836 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0290767 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0288192 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.028749 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0286751 |
| CALU | calumenin | 0.0284676 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0279116 |
| PLEC | plectin | 0.0279001 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278334 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0271675 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0271535 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0269643 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0268864 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0268151 |
| BCL2L1 | BCL2-like 1 | 0.0266985 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.026585 |
| GOLGA4 | golgin A4 | 0.0265677 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0265661 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0263112 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0262409 |
| ADM | adrenomedullin | 0.0262385 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0259262 |
| CTBP2 | C-terminal binding protein 2 | 0.0257914 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.0257812 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.283457 |
| TMSB10 | thymosin beta 10 | -0.226322 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.122078 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.103046 |
| MYADM | myeloid-associated differentiation marker | -0.0583505 |
| SUCNR1 | succinate receptor 1 | -0.0570003 |
| LOX | lysyl oxidase | -0.0565185 |
| MX2 | MX dynamin-like GTPase 2 | -0.0547995 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0540215 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0534516 |
| POTEF | POTE ankyrin domain family, member F | -0.0484358 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0479602 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.046576 |
| FN1 | fibronectin 1 | -0.0463182 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0411783 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0396415 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0366885 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0358331 |
| NAV1 | neuron navigator 1 | -0.0352093 |
| PFN1 | profilin 1 | -0.0345211 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0323223 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0322072 |
| HLA-B | major histocompatibility complex, class I, B | -0.0312344 |
| PODXL | podocalyxin-like | -0.0294718 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0288883 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.028725 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0281772 |
| TPM1 | tropomyosin 1 (alpha) | -0.0281253 |
| VIM | vimentin | -0.0271225 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0271092 |
| MT1X | metallothionein 1X | -0.026875 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0257546 |
| FRMD4A | FERM domain containing 4A | -0.0251817 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0249652 |
| TAGLN2 | transgelin 2 | -0.0248578 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0241682 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0239906 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0230832 |
| S100A4 | S100 calcium binding protein A4 | -0.0230767 |
| S100A6 | S100 calcium binding protein A6 | -0.021769 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0213642 |
| TNS3 | tensin 3 | -0.0213026 |
| MAP1B | microtubule-associated protein 1B | -0.0209545 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0209215 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0201324 |
| HLA-C | major histocompatibility complex, class I, C | -0.0198784 |
| MT2A | metallothionein 2A | -0.0198313 |
| TAPBP | TAP binding protein (tapasin) | -0.0195489 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0194938 |
| RIGI | RNA sensor RIG-I | -0.0190722 |
| HSPB1 | heat shock 27kDa protein 1 | -0.018571 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0182839 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.017953 |
| S100A10 | S100 calcium binding protein A10 | -0.017893 |
| VEGFC | vascular endothelial growth factor C | -0.0178305 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0178169 |
| SMIM44 | small integral membrane protein 44 | -0.0175541 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0173696 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0173262 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0169846 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.016922 |
| BSG | basigin (Ok blood group) | -0.0167571 |
| PRSS23 | protease, serine, 23 | -0.0167283 |
| TENM3 | teneurin transmembrane protein 3 | -0.0161872 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0155835 |
| KRT81 | keratin 81, type II | -0.0155563 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0154904 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0154648 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0153772 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0153258 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0148555 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0148406 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0143647 |
| RNF213 | ring finger protein 213 | -0.0142371 |
| JAZF1 | JAZF zinc finger 1 | -0.0141799 |
| SP100 | SP100 nuclear antigen | -0.0141626 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0141166 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0141092 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0140212 |
| FRMD5 | FERM domain containing 5 | -0.013818 |
| NPR2 | natriuretic peptide receptor 2 | -0.0137777 |
| CBX3 | chromobox homolog 3 | -0.0137543 |
| KATNAL1 | katanin p60 subunit A-like 1 | -0.01358 |
| CAPNS1 | calpain, small subunit 1 | -0.0134819 |
| IFI44L | interferon-induced protein 44-like | -0.0133345 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.013328 |
| COL5A1 | collagen, type V, alpha 1 | -0.0132403 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0131552 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.012967 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0129591 |
| CPLANE1 | ciliogenesis and planar polarity effector complex subunit 1 | -0.0126806 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0126317 |
| CCND1 | cyclin D1 | -0.0126307 |
| MXRA5 | matrix-remodelling associated 5 | -0.0125878 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0125579 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0124539 |
| PLSCR1 | phospholipid scramblase 1 | -0.0123811 |
| GDI1 | GDP dissociation inhibitor 1 | -0.0122538 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0122172 |
| AGRN | agrin | -0.0121872 |
