| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.233783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.13437 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.117049 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0991293 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0937622 |
| CDH13 | cadherin 13 | 0.0936912 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0927172 |
| COL1A2 | collagen, type I, alpha 2 | 0.0912209 |
| ENO1 | enolase 1, (alpha) | 0.0777572 |
| CADM1 | cell adhesion molecule 1 | 0.0735926 |
| CANX | calnexin | 0.0703903 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0687123 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0681146 |
| NDRG1 | N-myc downstream regulated 1 | 0.0646243 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0627377 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0608801 |
| CALR | calreticulin | 0.0603057 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.059005 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0520206 |
| VEGFA | vascular endothelial growth factor A | 0.0507175 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0505846 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0504636 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0481202 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0452566 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0436075 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0434712 |
| RPS8 | ribosomal protein S8 | 0.0432958 |
| FBN1 | fibrillin 1 | 0.0430977 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0429882 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0421078 |
| CALU | calumenin | 0.0412656 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0407694 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0398373 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0393181 |
| COL5A1 | collagen, type V, alpha 1 | 0.0386895 |
| GOLGB1 | golgin B1 | 0.0376945 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0372641 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0362977 |
| ASPH | aspartate beta-hydroxylase | 0.036261 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0360964 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.035912 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0352103 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0347998 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0345466 |
| SQSTM1 | sequestosome 1 | 0.0345071 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0337037 |
| PTK2 | protein tyrosine kinase 2 | 0.033365 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0319582 |
| ADM | adrenomedullin | 0.0319484 |
| STC2 | stanniocalcin 2 | 0.0314941 |
| MTDH | metadherin | 0.0313247 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0312536 |
| RAB2A | RAB2A, member RAS oncogene family | 0.031215 |
| MYO10 | myosin X | 0.0303959 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0298012 |
| GOLGA4 | golgin A4 | 0.0292459 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0291092 |
| PGM3 | phosphoglucomutase 3 | 0.0290771 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0286813 |
| GANAB | glucosidase, alpha; neutral AB | 0.0281561 |
| POSTN | periostin, osteoblast specific factor | 0.0281407 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0276741 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0275688 |
| COL3A1 | collagen, type III, alpha 1 | 0.0270489 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0270109 |
| FN1 | fibronectin 1 | 0.0267524 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0264896 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0264151 |
| PDE10A | phosphodiesterase 10A | 0.0263823 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0259668 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0249549 |
| RPS12 | ribosomal protein S12 | 0.0245814 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0240997 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0236365 |
| NAV2 | neuron navigator 2 | 0.0234096 |
| YBX1 | Y box binding protein 1 | 0.0228767 |
| JUN | jun proto-oncogene | 0.0228756 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0227947 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0226843 |
| RND3 | Rho family GTPase 3 | 0.0226 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0225972 |
| ARRDC3 | arrestin domain containing 3 | 0.0223863 |
| RPS3 | ribosomal protein S3 | 0.0219838 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0219152 |
| HYOU1 | hypoxia up-regulated 1 | 0.021744 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0216842 |
| TPM3 | tropomyosin 3 | 0.021298 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0212489 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0211981 |
| ANKRD11 | ankyrin repeat domain 11 | 0.020938 |
| QKI | QKI, KH domain containing, RNA binding | 0.0209097 |
| FNIP1 | folliculin interacting protein 1 | 0.0207744 |
| TRAM1 | translocation associated membrane protein 1 | 0.0207699 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0207579 |
| PCBP2 | poly(rC) binding protein 2 | 0.0206779 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0206772 |
| CCNY | cyclin Y | 0.0205919 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0204743 |
| TFG | TRK-fused gene | 0.0204153 |
| DST | dystonin | 0.0203741 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.1071 |
| MT2A | metallothionein 2A | -0.0696132 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0694982 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0336315 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0324073 |
| HMGA2 | high mobility group AT-hook 2 | -0.0312829 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0307129 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0289187 |
| MT1X | metallothionein 1X | -0.0286881 |
| OSMR | oncostatin M receptor | -0.0270552 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0265511 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0248043 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0247818 |
| PALLD | palladin, cytoskeletal associated protein | -0.0225057 |
| GLIS3 | GLIS family zinc finger 3 | -0.0219749 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0214146 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0211192 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0202547 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0188444 |
| RIGI | RNA sensor RIG-I | -0.0184892 |
| HAS2 | hyaluronan synthase 2 | -0.0176342 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0174285 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0169599 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0168398 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0167009 |
| VCL | vinculin | -0.0166994 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0166088 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.015324 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0152641 |
| RPLP1 | ribosomal protein, large, P1 | -0.0145003 |
| EBF1 | early B-cell factor 1 | -0.0140567 |
| CAVIN1 | caveolae associated protein 1 | -0.0136647 |
| RPL32 | ribosomal protein L32 | -0.0136279 |
| MAP1B | microtubule-associated protein 1B | -0.0131656 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0131372 |
| FRMD4A | FERM domain containing 4A | -0.0131341 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0131172 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0130497 |
| KLF6 | Kruppel-like factor 6 | -0.012804 |
| FTL | ferritin, light polypeptide | -0.0125109 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0122143 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0120813 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0119868 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0119281 |
| NREP | neuronal regeneration related protein | -0.0118606 |
| STK38L | serine/threonine kinase 38 like | -0.0118347 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0117201 |
| EHD2 | EH-domain containing 2 | -0.0117147 |
| AOPEP | aminopeptidase O (putative) | -0.0116986 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.011564 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0115363 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0112902 |
| JAK2 | Janus kinase 2 | -0.0112746 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0111285 |
| S100A6 | S100 calcium binding protein A6 | -0.0110178 |
| EGR1 | early growth response 1 | -0.0109773 |
| PLSCR1 | phospholipid scramblase 1 | -0.0108414 |
| MTSS1 | metastasis suppressor 1 | -0.0107093 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0104235 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.0102849 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0102556 |
| ACTN4 | actinin, alpha 4 | -0.0102104 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.00986166 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.00976458 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.00953816 |
| CAPNS1 | calpain, small subunit 1 | -0.00949697 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00926184 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.00914797 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.00905954 |
| JMJD1C | jumonji domain containing 1C | -0.0090531 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00904026 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00902992 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0090035 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0089648 |
| COL1A1 | collagen, type I, alpha 1 | -0.00896066 |
| KIAA1217 | KIAA1217 | -0.00894434 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00892158 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0088967 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0088563 |
| FAM20C | family with sequence similarity 20, member C | -0.0087581 |
| RPS24 | ribosomal protein S24 | -0.00875549 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00862239 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00859097 |
| CBX3 | chromobox homolog 3 | -0.00858818 |
| SH3PXD2B | SH3 and PX domains 2B | -0.00841114 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.00825675 |
| FHL2 | four and a half LIM domains 2 | -0.00821615 |
| TPM1 | tropomyosin 1 (alpha) | -0.00818344 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.00816542 |
| TAPBP | TAP binding protein (tapasin) | -0.00808743 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.00808163 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.00805937 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.00805298 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00795192 |
| SMAD3 | SMAD family member 3 | -0.00792818 |
| GPR141 | G protein-coupled receptor 141 | -0.00790593 |
| RPS19 | ribosomal protein S19 | -0.00776095 |
| MX2 | MX dynamin-like GTPase 2 | -0.00774094 |
| TENM1 | teneurin transmembrane protein 1 | -0.00771411 |
| CFB | complement factor B | -0.00767946 |
