| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0851252 |
| CD44 | CD44 molecule (Indian blood group) | 0.082618 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0765898 |
| LMO7 | LIM domain 7 | 0.0666466 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0637418 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0563591 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0538338 |
| SMAD3 | SMAD family member 3 | 0.0537937 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0511411 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0471385 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0459107 |
| CLU | clusterin | 0.0458921 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.045386 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0440944 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0438063 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0436336 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0431753 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0387672 |
| ASPH | aspartate beta-hydroxylase | 0.0387408 |
| FAM107B | family with sequence similarity 107, member B | 0.0382825 |
| TGM2 | transglutaminase 2 | 0.0372072 |
| TPM3 | tropomyosin 3 | 0.0368296 |
| SIK3 | SIK family kinase 3 | 0.0363286 |
| CANX | calnexin | 0.0358754 |
| FNDC3B | fibronectin type III domain containing 3B | 0.035027 |
| MCL1 | myeloid cell leukemia 1 | 0.0342409 |
| PLEC | plectin | 0.0330369 |
| RIN2 | Ras and Rab interactor 2 | 0.0325699 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0323757 |
| STC1 | stanniocalcin 1 | 0.0313014 |
| ARRDC3 | arrestin domain containing 3 | 0.0300688 |
| MYOF | myoferlin | 0.0300454 |
| SEPTIN9 | septin 9 | 0.0299149 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0295105 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0288787 |
| ANO6 | anoctamin 6 | 0.0284448 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0275774 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0270104 |
| KIAA1217 | KIAA1217 | 0.0269257 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0265526 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0263727 |
| JMJD1C | jumonji domain containing 1C | 0.0262928 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0249933 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0249187 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0247887 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0246902 |
| ANXA1 | annexin A1 | 0.0244963 |
| MSN | moesin | 0.0244193 |
| FNIP1 | folliculin interacting protein 1 | 0.0243936 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0234997 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0232739 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0228521 |
| TXNIP | thioredoxin interacting protein | 0.0228246 |
| CEP250 | centrosomal protein 250kDa | 0.0228234 |
| GOLGB1 | golgin B1 | 0.0226968 |
| PRELID2 | PRELI domain containing 2 | 0.0224021 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0220117 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0219234 |
| RPS2 | ribosomal protein S2 | 0.0218452 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0218039 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.021777 |
| DST | dystonin | 0.0217169 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.021504 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0211263 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0207258 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0206623 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.020331 |
| VMP1 | vacuole membrane protein 1 | 0.0202989 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0202911 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0202835 |
| NAV2 | neuron navigator 2 | 0.0197432 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0196809 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0196633 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0195354 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0195274 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0191423 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0190359 |
| BARX2 | BARX homeobox 2 | 0.0189454 |
| ADAR | adenosine deaminase, RNA-specific | 0.0188473 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0188161 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0187584 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0187449 |
| CUL4B | cullin 4B | 0.0187423 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0187289 |
| IL6ST | interleukin 6 signal transducer | 0.0183555 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0181731 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0181706 |
| SVIL | supervillin | 0.0179847 |
| RPL7 | ribosomal protein L7 | 0.0178959 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0178554 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0177337 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0174673 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0174194 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0172716 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0171519 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0171434 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0168981 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0167365 |
| CDK17 | cyclin-dependent kinase 17 | 0.0167073 |
| RAI14 | retinoic acid induced 14 | 0.016633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.2651 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.168966 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.106003 |
| FLNB | filamin B, beta | -0.105382 |
| TMSB10 | thymosin beta 10 | -0.100633 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0921401 |
| NDRG1 | N-myc downstream regulated 1 | -0.0682568 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0625478 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0621617 |
| POTEF | POTE ankyrin domain family, member F | -0.0616085 |
| S100A10 | S100 calcium binding protein A10 | -0.0578071 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0568382 |
| PODXL | podocalyxin-like | -0.056623 |
| IGF2 | insulin-like growth factor 2 | -0.0508218 |
| GNAS | GNAS complex locus | -0.050055 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0493108 |
| LDHA | lactate dehydrogenase A | -0.0428797 |
| LAMA5 | laminin, alpha 5 | -0.0406299 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0393124 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0392303 |
| SQLE | squalene epoxidase | -0.0374641 |
| PTMA | prothymosin, alpha | -0.0370357 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0355668 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0348616 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0348371 |
| H1-0 | H1.0 linker histone | -0.0330973 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0319106 |
| RPS24 | ribosomal protein S24 | -0.0318944 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0309931 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0308093 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0306292 |
| PALLD | palladin, cytoskeletal associated protein | -0.0302676 |
| MT1X | metallothionein 1X | -0.0288763 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0288537 |
| MEF2A | myocyte enhancer factor 2A | -0.0277477 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0277072 |
| PKM | pyruvate kinase, muscle | -0.0272712 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0272614 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0272055 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0260957 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0252667 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0251545 |
| HMGA1 | high mobility group AT-hook 1 | -0.0250551 |
| THBD | thrombomodulin | -0.0250357 |
| EGR1 | early growth response 1 | -0.0247574 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0246172 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0244324 |
| TMEM165 | transmembrane protein 165 | -0.0240977 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.023817 |
| S100A6 | S100 calcium binding protein A6 | -0.0238031 |
| RPS21 | ribosomal protein S21 | -0.023765 |
| SULF1 | sulfatase 1 | -0.0236813 |
| CSNK1E | casein kinase 1, epsilon | -0.0233171 |
| RPL34 | ribosomal protein L34 | -0.0232561 |
| SULF2 | sulfatase 2 | -0.0230202 |
| RPL35A | ribosomal protein L35a | -0.0228375 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.0227295 |
| ACTN4 | actinin, alpha 4 | -0.0227084 |
| PFN1 | profilin 1 | -0.0223096 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0221759 |
| TMSB4X | thymosin beta 4, X-linked | -0.0219668 |
| FTL | ferritin, light polypeptide | -0.0217714 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0217102 |
| LMNA | lamin A/C | -0.021667 |
| WASF2 | WAS protein family, member 2 | -0.0212117 |
| RPLP1 | ribosomal protein, large, P1 | -0.0207515 |
| GUK1 | guanylate kinase 1 | -0.0207272 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0206953 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0204806 |
| FOSL1 | FOS-like antigen 1 | -0.0202693 |
| EPHA2 | EPH receptor A2 | -0.0202077 |
| S100A2 | S100 calcium binding protein A2 | -0.0198074 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0198031 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0196017 |
| S100A11 | S100 calcium binding protein A11 | -0.019512 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0193269 |
| SERTAD2 | SERTA domain containing 2 | -0.0191586 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0189624 |
| ARF1 | ADP-ribosylation factor 1 | -0.018428 |
| KRT17 | keratin 17, type I | -0.0183872 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0182739 |
| ITGB4 | integrin, beta 4 | -0.0180892 |
| RPLP0 | ribosomal protein, large, P0 | -0.0180297 |
| S100A4 | S100 calcium binding protein A4 | -0.0179526 |
| CAVIN1 | caveolae associated protein 1 | -0.0179471 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0178914 |
| FOXO3 | forkhead box O3 | -0.0178763 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0177847 |
| RPL11 | ribosomal protein L11 | -0.0175449 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0174723 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0171819 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0170281 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0168107 |
| RPS25 | ribosomal protein S25 | -0.0167183 |
| RPL32 | ribosomal protein L32 | -0.0167091 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.016707 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0166915 |
| OXR1 | oxidation resistance 1 | -0.0166405 |
| TAGLN2 | transgelin 2 | -0.0166166 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0165211 |
