| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0877909 |
| LMO7 | LIM domain 7 | 0.0843803 |
| AREG | amphiregulin | 0.0661204 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0542246 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0481371 |
| CMIP | c-Maf inducing protein | 0.0418097 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0386947 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379731 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0333506 |
| HM13 | histocompatibility (minor) 13 | 0.0329145 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0323871 |
| SEPTIN9 | septin 9 | 0.0312959 |
| HYOU1 | hypoxia up-regulated 1 | 0.0312425 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0298455 |
| GOLGB1 | golgin B1 | 0.0288832 |
| GDA | guanine deaminase | 0.0285855 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0281667 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0260602 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0252181 |
| ANXA1 | annexin A1 | 0.0250689 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0249106 |
| FAM107B | family with sequence similarity 107, member B | 0.0242365 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0227844 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0227133 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0226297 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0223142 |
| VMP1 | vacuole membrane protein 1 | 0.0221612 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0218344 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0212944 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0212047 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0210816 |
| PTMA | prothymosin, alpha | 0.0208417 |
| NDRG1 | N-myc downstream regulated 1 | 0.0205177 |
| TXNRD1 | thioredoxin reductase 1 | 0.0204198 |
| CUX1 | cut-like homeobox 1 | 0.0201937 |
| SIK3 | SIK family kinase 3 | 0.0197422 |
| PLEC | plectin | 0.0195246 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0188813 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0187673 |
| IER3 | immediate early response 3 | 0.0185112 |
| TFF1 | trefoil factor 1 | 0.0184604 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0184276 |
| PGM3 | phosphoglucomutase 3 | 0.0184196 |
| CDK13 | cyclin-dependent kinase 13 | 0.0182406 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0180089 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0178105 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0177124 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0176107 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0173009 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0169999 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0169459 |
| HELZ | helicase with zinc finger | 0.0169361 |
| RCOR1 | REST corepressor 1 | 0.0168298 |
| SNX9 | sorting nexin 9 | 0.0165065 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0165041 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0163143 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0162004 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0161484 |
| CLTC | clathrin, heavy chain (Hc) | 0.0159442 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0157916 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0157099 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0156644 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.015404 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0153206 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0152963 |
| BRD2 | bromodomain containing 2 | 0.0151041 |
| SERINC3 | serine incorporator 3 | 0.0150111 |
| GTPBP2 | GTP binding protein 2 | 0.0146995 |
| MCL1 | myeloid cell leukemia 1 | 0.0146196 |
| MUC13 | mucin 13, cell surface associated | 0.014614 |
| HBP1 | HMG-box transcription factor 1 | 0.0145413 |
| USP53 | ubiquitin specific peptidase 53 | 0.0144959 |
| MYO1E | myosin IE | 0.0143499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0143096 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0142597 |
| LIPH | lipase, member H | 0.014182 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0141786 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0140186 |
| VEGFA | vascular endothelial growth factor A | 0.0140115 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.013935 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0139011 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0138618 |
| TJP1 | tight junction protein 1 | 0.0138516 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0137971 |
| RPL31 | ribosomal protein L31 | 0.013716 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0136173 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0136077 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0135995 |
| GANAB | glucosidase, alpha; neutral AB | 0.0135211 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0134889 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0134856 |
| MPZL3 | myelin protein zero-like 3 | 0.0134363 |
| PMM2 | phosphomannomutase 2 | 0.0134263 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0133396 |
| MYOF | myoferlin | 0.0133272 |
| ZNF146 | zinc finger protein 146 | 0.013208 |
| SGMS2 | sphingomyelin synthase 2 | 0.0131169 |
| SMAD3 | SMAD family member 3 | 0.01296 |
| VIM | vimentin | 0.0127849 |
| RRM2 | ribonucleotide reductase M2 | 0.0124563 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | -0.287192 |
| NPSR1 | neuropeptide S receptor 1 | -0.178415 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.112498 |
| TMSB10 | thymosin beta 10 | -0.102398 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.100956 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0943206 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0658126 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.054137 |
| KRT8 | keratin 8, type II | -0.0519575 |
| CDK6 | cyclin-dependent kinase 6 | -0.0498365 |
| H1-0 | H1.0 linker histone | -0.0495776 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0462351 |
| KRT18 | keratin 18, type I | -0.0428768 |
| S100A6 | S100 calcium binding protein A6 | -0.0409226 |
| TMSB4X | thymosin beta 4, X-linked | -0.040645 |
| EHBP1 | EH domain binding protein 1 | -0.040501 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0398683 |
| RPL23 | ribosomal protein L23 | -0.0395025 |
| RPL26 | ribosomal protein L26 | -0.0394438 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0383002 |
| ACTN4 | actinin, alpha 4 | -0.0380843 |
| B2M | beta-2-microglobulin | -0.0378292 |
| POTEF | POTE ankyrin domain family, member F | -0.0374538 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0363408 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0362516 |
| RRBP1 | ribosome binding protein 1 | -0.0346823 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0345375 |
| GPX2 | glutathione peroxidase 2 | -0.0339723 |
| RUNX1 | runt-related transcription factor 1 | -0.0332504 |
| PLSCR1 | phospholipid scramblase 1 | -0.0326286 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0325021 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0320653 |
| RPL18 | ribosomal protein L18 | -0.0319355 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0315238 |
| RPS19 | ribosomal protein S19 | -0.0313798 |
| GNAS | GNAS complex locus | -0.031084 |
| RPL12 | ribosomal protein L12 | -0.0310391 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307775 |
| INSIG1 | insulin induced gene 1 | -0.0307554 |
| AHNAK | AHNAK nucleoprotein | -0.0305087 |
| FLNB | filamin B, beta | -0.0301207 |
| ATF5 | activating transcription factor 5 | -0.0298441 |
| AHR | aryl hydrocarbon receptor | -0.0295825 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0292539 |
| RPS21 | ribosomal protein S21 | -0.0291827 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0284307 |
| TMEM123 | transmembrane protein 123 | -0.0282834 |
| EPCAM | epithelial cell adhesion molecule | -0.0282223 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0280745 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0273833 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0271409 |
| PFN1 | profilin 1 | -0.0269798 |
| HMGA1 | high mobility group AT-hook 1 | -0.0268349 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0268241 |
| POF1B | premature ovarian failure, 1B | -0.0268104 |
| NF1 | neurofibromin 1 | -0.0266331 |
| SHROOM3 | shroom family member 3 | -0.0262575 |
| S100A10 | S100 calcium binding protein A10 | -0.0262454 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0255628 |
| COBL | cordon-bleu WH2 repeat protein | -0.0252767 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0252425 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.025221 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0249825 |
| CD2AP | CD2-associated protein | -0.0248553 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0241829 |
| RAD51B | RAD51 paralog B | -0.0241113 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0239757 |
| AUTS2 | autism susceptibility candidate 2 | -0.0235177 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0233618 |
| PRELID2 | PRELI domain containing 2 | -0.0232331 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0230422 |
| PHF14 | PHD finger protein 14 | -0.0230234 |
| RPL19 | ribosomal protein L19 | -0.0227748 |
| ADD3 | adducin 3 (gamma) | -0.022586 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0224997 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0223278 |
| CBX3 | chromobox homolog 3 | -0.0221808 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0221492 |
| ACTG1 | actin gamma 1 | -0.0220865 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0219083 |
| ITGB4 | integrin, beta 4 | -0.0215433 |
| KRT19 | keratin 19, type I | -0.0215416 |
| RNF213 | ring finger protein 213 | -0.0215313 |
| FRMD5 | FERM domain containing 5 | -0.0209308 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0209102 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0206809 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0206647 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0205717 |
| RPS24 | ribosomal protein S24 | -0.0204321 |
| DEK | DEK proto-oncogene | -0.0203095 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0203037 |
| RPL34 | ribosomal protein L34 | -0.0202815 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0200336 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0200185 |
| NFIA | nuclear factor I/A | -0.0200063 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0199389 |
| RPL32 | ribosomal protein L32 | -0.0197742 |
| OXR1 | oxidation resistance 1 | -0.0196261 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0195847 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0195747 |
