| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.22206 |
| MT2A | metallothionein 2A | 0.13887 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109705 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0984823 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0966243 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0883539 |
| RPS8 | ribosomal protein S8 | 0.0771954 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0743453 |
| CAPRIN2 | caprin family member 2 | 0.0690844 |
| RPL12 | ribosomal protein L12 | 0.0640626 |
| TXNIP | thioredoxin interacting protein | 0.0612097 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0592162 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0575888 |
| MT1X | metallothionein 1X | 0.0573866 |
| SPAG9 | sperm associated antigen 9 | 0.0573125 |
| RPS12 | ribosomal protein S12 | 0.0553631 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0551356 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0549076 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0543194 |
| RPL26 | ribosomal protein L26 | 0.052367 |
| JUN | jun proto-oncogene | 0.0520347 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0490009 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0489007 |
| SLK | STE20-like kinase | 0.0487658 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0483224 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0467741 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0460658 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0460413 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0454584 |
| FNIP1 | folliculin interacting protein 1 | 0.0451531 |
| AHNAK | AHNAK nucleoprotein | 0.0450278 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0443685 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0435662 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0428073 |
| TPM3 | tropomyosin 3 | 0.0427887 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0416683 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.040954 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0405738 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0395293 |
| ARRDC3 | arrestin domain containing 3 | 0.0394049 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0387216 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0380329 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0369724 |
| PRELID2 | PRELI domain containing 2 | 0.0360718 |
| ENO1 | enolase 1, (alpha) | 0.0359157 |
| EREG | epiregulin | 0.0358144 |
| MT1E | metallothionein 1E | 0.0354856 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0350189 |
| SON | SON DNA binding protein | 0.0342166 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0329443 |
| SVIL | supervillin | 0.0319891 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0315527 |
| EMP1 | epithelial membrane protein 1 | 0.0315022 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0308099 |
| LDHA | lactate dehydrogenase A | 0.030789 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0306134 |
| ADM | adrenomedullin | 0.0304926 |
| ANGPTL4 | angiopoietin-like 4 | 0.0297298 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0292515 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0289016 |
| HDAC9 | histone deacetylase 9 | 0.0285129 |
| SQSTM1 | sequestosome 1 | 0.0284966 |
| PRKCE | protein kinase C, epsilon | 0.0276506 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0276481 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0270077 |
| RPL18 | ribosomal protein L18 | 0.0269282 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0268695 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0267702 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0267207 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0265369 |
| KRT18 | keratin 18, type I | 0.0264171 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0263999 |
| GOLGB1 | golgin B1 | 0.0262577 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0260749 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0259286 |
| VEGFC | vascular endothelial growth factor C | 0.0258866 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0258367 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0257729 |
| CANX | calnexin | 0.0255908 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0255878 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0252346 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0251464 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0248195 |
| ANK2 | ankyrin 2, neuronal | 0.0245438 |
| ADAR | adenosine deaminase, RNA-specific | 0.0244886 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0242745 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.024255 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0239513 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0238365 |
| KLF6 | Kruppel-like factor 6 | 0.023489 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0233663 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0232949 |
| CD44 | CD44 molecule (Indian blood group) | 0.0232356 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0231045 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0228484 |
| MEF2A | myocyte enhancer factor 2A | 0.022753 |
| PLK2 | polo-like kinase 2 | 0.0225811 |
| AREG | amphiregulin | 0.0220265 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0220173 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0219891 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.282972 |
| PTMA | prothymosin, alpha | -0.167244 |
| VIM | vimentin | -0.152425 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101204 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0966493 |
| FTL | ferritin, light polypeptide | -0.0951586 |
| POTEF | POTE ankyrin domain family, member F | -0.0853545 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0770897 |
| TXNRD1 | thioredoxin reductase 1 | -0.0738425 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0727626 |
| RPS24 | ribosomal protein S24 | -0.0704539 |
| ACTG1 | actin gamma 1 | -0.0683244 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0652146 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0640841 |
| TP63 | tumor protein p63 | -0.0635056 |
| RPL31 | ribosomal protein L31 | -0.0591154 |
| RPL35A | ribosomal protein L35a | -0.058181 |
| RPLP1 | ribosomal protein, large, P1 | -0.0554886 |
| CAVIN1 | caveolae associated protein 1 | -0.0533026 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0520597 |
| EGR1 | early growth response 1 | -0.0501756 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0490556 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0487709 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0479566 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0464367 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0444748 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0435008 |
| GNAS | GNAS complex locus | -0.0404936 |
| RPL36A | ribosomal protein L36a | -0.0397252 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0390929 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0386204 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0385797 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.037878 |
| HLA-B | major histocompatibility complex, class I, B | -0.0377825 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0376345 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0369781 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0369086 |
| FBXO11 | F-box protein 11 | -0.0368437 |
| RPL7A | ribosomal protein L7a | -0.0366267 |
| TOP1 | topoisomerase (DNA) I | -0.0354805 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.035462 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0349257 |
| RPL38 | ribosomal protein L38 | -0.0340075 |
| RPL28 | ribosomal protein L28 | -0.0338321 |
| EHBP1 | EH domain binding protein 1 | -0.0337836 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0332275 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0328509 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0318775 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.030326 |
| WASF2 | WAS protein family, member 2 | -0.0300345 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0300051 |
| SEPTIN7 | septin 7 | -0.0298692 |
| EFNA5 | ephrin-A5 | -0.0294619 |
| RPL4 | ribosomal protein L4 | -0.0285969 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0283731 |
| TMEM123 | transmembrane protein 123 | -0.0283588 |
| NPR2 | natriuretic peptide receptor 2 | -0.0280674 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.028052 |
| OGA | O-GlcNAcase | -0.0280507 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.027842 |
| FOXK1 | forkhead box K1 | -0.0275401 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0275251 |
| WDR45B | WD repeat domain 45B | -0.027523 |
| PKM | pyruvate kinase, muscle | -0.0273124 |
| EPHA4 | EPH receptor A4 | -0.0272611 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0270541 |
| TFRC | transferrin receptor | -0.0266864 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.026238 |
| SP100 | SP100 nuclear antigen | -0.0261982 |
| MEMO1 | mediator of cell motility 1 | -0.0256049 |
| BMERB1 | bMERB domain containing 1 | -0.0255631 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0252371 |
| RPL11 | ribosomal protein L11 | -0.0251129 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0249097 |
| TMEM41B | transmembrane protein 41B | -0.0248273 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0248193 |
| RPS20 | ribosomal protein S20 | -0.024813 |
| TNS3 | tensin 3 | -0.0248004 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0245427 |
| RPL37 | ribosomal protein L37 | -0.0242455 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0242401 |
| MATR3 | matrin 3 | -0.024121 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0240653 |
| RPS14 | ribosomal protein S14 | -0.0239743 |
| RHEB | Ras homolog enriched in brain | -0.0237841 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.023757 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0232199 |
| RPS28 | ribosomal protein S28 | -0.023079 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0230748 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0229223 |
| RPS25 | ribosomal protein S25 | -0.0227705 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0226843 |
| NF1 | neurofibromin 1 | -0.0226475 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0225633 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0225557 |
| RIGI | RNA sensor RIG-I | -0.0223578 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0223404 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0222685 |
| TBCA | tubulin folding cofactor A | -0.0222597 |
| RPLP2 | ribosomal protein, large, P2 | -0.022233 |
