| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.168554 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.166423 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.116492 |
| GRAMD1B | GRAM domain containing 1B | 0.0979662 |
| MCL1 | myeloid cell leukemia 1 | 0.0901826 |
| STC1 | stanniocalcin 1 | 0.0722002 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0693522 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0679832 |
| CES1 | carboxylesterase 1 | 0.0676563 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0614314 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0576767 |
| CANX | calnexin | 0.0520295 |
| ARRDC3 | arrestin domain containing 3 | 0.049772 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0462067 |
| FAM13A | family with sequence similarity 13, member A | 0.0445537 |
| PYGL | phosphorylase, glycogen, liver | 0.0428178 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0416746 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0413913 |
| ENO1 | enolase 1, (alpha) | 0.0399496 |
| LMO7 | LIM domain 7 | 0.0393537 |
| GOLGB1 | golgin B1 | 0.03909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0376516 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0370695 |
| SPAG9 | sperm associated antigen 9 | 0.0364796 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0362794 |
| JMJD1C | jumonji domain containing 1C | 0.0361776 |
| HYOU1 | hypoxia up-regulated 1 | 0.0348377 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0338907 |
| JUN | jun proto-oncogene | 0.0332073 |
| MYO1E | myosin IE | 0.0331393 |
| MLF1 | myeloid leukemia factor 1 | 0.0329346 |
| SIK3 | SIK family kinase 3 | 0.0329035 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0320352 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0316553 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0314664 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0306499 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0304682 |
| HDLBP | high density lipoprotein binding protein | 0.0302779 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0300725 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0297383 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0296873 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0296664 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0293968 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0292133 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0292007 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0290699 |
| NDRG1 | N-myc downstream regulated 1 | 0.0286628 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0286347 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0283342 |
| CALR | calreticulin | 0.0282393 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0274077 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0273719 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.027141 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0271276 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0262229 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0261644 |
| EZR | ezrin | 0.0261462 |
| CUL4A | cullin 4A | 0.0260857 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0256668 |
| ATP13A3 | ATPase type 13A3 | 0.0256624 |
| PAPOLA | poly(A) polymerase alpha | 0.0256274 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.025609 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0254878 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0247086 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0243862 |
| ATP11A | ATPase, class VI, type 11A | 0.0243546 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0243459 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0241019 |
| EMP1 | epithelial membrane protein 1 | 0.0240168 |
| ENSA | endosulfine alpha | 0.0239463 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0236878 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0236872 |
| HBP1 | HMG-box transcription factor 1 | 0.0234168 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0231395 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0229692 |
| MYO5B | myosin VB | 0.0225492 |
| LAMB3 | laminin, beta 3 | 0.0224909 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0224679 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0223451 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0221559 |
| CRY1 | cryptochrome circadian clock 1 | 0.0221416 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.022136 |
| PGK1 | phosphoglycerate kinase 1 | 0.0220742 |
| ANXA1 | annexin A1 | 0.0219945 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0218751 |
| LAMA4 | laminin, alpha 4 | 0.021808 |
| BRD2 | bromodomain containing 2 | 0.021766 |
| ATF6 | activating transcription factor 6 | 0.0215118 |
| MSN | moesin | 0.0214324 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0214322 |
| PTMA | prothymosin, alpha | 0.0209106 |
| MPZL3 | myelin protein zero-like 3 | 0.0209033 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0208942 |
| TPM3 | tropomyosin 3 | 0.0207813 |
| SMAD3 | SMAD family member 3 | 0.0207708 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0206625 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.020582 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0205463 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0204851 |
| TMEM45B | transmembrane protein 45B | 0.020206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.173092 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0777603 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0689825 |
| ASPH | aspartate beta-hydroxylase | -0.0593682 |
| TMSB10 | thymosin beta 10 | -0.0517899 |
| EFNA5 | ephrin-A5 | -0.0499971 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0496721 |
| SCEL | sciellin | -0.0488839 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0456026 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0449683 |
| KRT7 | keratin 7, type II | -0.0409249 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0384344 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0352665 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0347081 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0346721 |
| RNF213 | ring finger protein 213 | -0.0336643 |
| ACTG1 | actin gamma 1 | -0.0327383 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0322864 |
| S100A10 | S100 calcium binding protein A10 | -0.0318358 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0313678 |
| TNS3 | tensin 3 | -0.02965 |
| PKM | pyruvate kinase, muscle | -0.0278295 |
| RPL35A | ribosomal protein L35a | -0.0275421 |
| PRKCA | protein kinase C, alpha | -0.0272616 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0270128 |
| MYOF | myoferlin | -0.0270099 |
| RPS3 | ribosomal protein S3 | -0.0268322 |
| CCND1 | cyclin D1 | -0.0264255 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0254443 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0252943 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0241337 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0238618 |
| HMGA1 | high mobility group AT-hook 1 | -0.0233449 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0229587 |
| PCED1B | PC-esterase domain containing 1B | -0.0229073 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0222543 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0220363 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0209533 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0207494 |
| KRT18 | keratin 18, type I | -0.0207289 |
| RPS24 | ribosomal protein S24 | -0.0205322 |
| RBM25 | RNA binding motif protein 25 | -0.0199642 |
| POTEF | POTE ankyrin domain family, member F | -0.0198221 |
| EHBP1 | EH domain binding protein 1 | -0.0194366 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0192668 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0188425 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0187593 |
| MAP7 | microtubule-associated protein 7 | -0.0187094 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0186644 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0181833 |
| KRT8 | keratin 8, type II | -0.0177376 |
| TXNRD1 | thioredoxin reductase 1 | -0.017691 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0176867 |
| RPS23 | ribosomal protein S23 | -0.0174805 |
| CCNL1 | cyclin L1 | -0.0173491 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0172339 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.017176 |
| PFN1 | profilin 1 | -0.0171624 |
| ANXA2 | annexin A2 | -0.0168854 |
| LAMA5 | laminin, alpha 5 | -0.0167065 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0166231 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0165947 |
| MT1X | metallothionein 1X | -0.0165844 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0165751 |
| FTL | ferritin, light polypeptide | -0.0162488 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0160255 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0159834 |
| KRT19 | keratin 19, type I | -0.015889 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0158301 |
| NTN4 | netrin 4 | -0.0157871 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0157432 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0157153 |
| PMP22 | peripheral myelin protein 22 | -0.0156947 |
| RNF145 | ring finger protein 145 | -0.0156457 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0156398 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0155161 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0154869 |
| TCERG1 | transcription elongation regulator 1 | -0.0153156 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0152915 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0152892 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0152103 |
| SP100 | SP100 nuclear antigen | -0.0151917 |
| SEC61G | Sec61 gamma subunit | -0.0151804 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.015141 |
| RIN2 | Ras and Rab interactor 2 | -0.0147845 |
| FLNB | filamin B, beta | -0.0144775 |
| RPL9 | ribosomal protein L9 | -0.0144098 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0143958 |
| CAB39 | calcium binding protein 39 | -0.0143313 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0142922 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0142889 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.014274 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0139306 |
| SLMAP | sarcolemma associated protein | -0.0139013 |
| OSMR | oncostatin M receptor | -0.0136891 |
| RPL34 | ribosomal protein L34 | -0.0136488 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0135795 |
| MT2A | metallothionein 2A | -0.0135559 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.013425 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0133469 |
