| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.139993 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.112073 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.110193 |
| LOX | lysyl oxidase | 0.100818 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0992085 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0762344 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0653952 |
| VIM | vimentin | 0.0652664 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0647863 |
| LOXL2 | lysyl oxidase-like 2 | 0.0591913 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0580518 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0565993 |
| FAM107B | family with sequence similarity 107, member B | 0.0529271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0524569 |
| ENO1 | enolase 1, (alpha) | 0.0522161 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0511331 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0506118 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.050348 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0503398 |
| CD44 | CD44 molecule (Indian blood group) | 0.0501092 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.047067 |
| SMAD3 | SMAD family member 3 | 0.0448131 |
| CANX | calnexin | 0.0447774 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0440703 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0439262 |
| CA12 | carbonic anhydrase XII | 0.042521 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.041814 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0416708 |
| PCBP2 | poly(rC) binding protein 2 | 0.0413114 |
| STC1 | stanniocalcin 1 | 0.0405369 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0401744 |
| AHNAK | AHNAK nucleoprotein | 0.040068 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0385485 |
| ASPH | aspartate beta-hydroxylase | 0.0383395 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0377154 |
| PYGL | phosphorylase, glycogen, liver | 0.0370297 |
| INTS6 | integrator complex subunit 6 | 0.0368754 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0364186 |
| NDRG1 | N-myc downstream regulated 1 | 0.0360674 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0358197 |
| EMP1 | epithelial membrane protein 1 | 0.0356899 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0348076 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0346005 |
| ANXA2 | annexin A2 | 0.0344109 |
| SEPTIN9 | septin 9 | 0.0340391 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0337569 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0337398 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0333346 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0326189 |
| ECE1 | endothelin converting enzyme 1 | 0.0325475 |
| ANGPTL4 | angiopoietin-like 4 | 0.0324349 |
| NAV2 | neuron navigator 2 | 0.0308602 |
| FLNB | filamin B, beta | 0.0305392 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0304746 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0300533 |
| ANO6 | anoctamin 6 | 0.0299924 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0299899 |
| ADM | adrenomedullin | 0.0297869 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0297213 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0296705 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.029656 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0296133 |
| ANXA1 | annexin A1 | 0.0288841 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.028664 |
| CALU | calumenin | 0.0283412 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0277832 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0276949 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0276746 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274421 |
| EZR | ezrin | 0.0273963 |
| FN1 | fibronectin 1 | 0.0269936 |
| LDHA | lactate dehydrogenase A | 0.026961 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0268792 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0265854 |
| CEP250 | centrosomal protein 250kDa | 0.0258511 |
| TGFB1 | transforming growth factor, beta 1 | 0.0254037 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0247595 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0246384 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0246272 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0245778 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0245513 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0242464 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0241747 |
| MYO10 | myosin X | 0.0239625 |
| SFTPA2 | surfactant protein A2 | 0.0238757 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0235171 |
| ARRDC3 | arrestin domain containing 3 | 0.0233473 |
| MCL1 | myeloid cell leukemia 1 | 0.0229601 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0226895 |
| SQSTM1 | sequestosome 1 | 0.0225304 |
| RCOR1 | REST corepressor 1 | 0.0223764 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0220621 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0220179 |
| FBN1 | fibrillin 1 | 0.0219049 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0216292 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0212155 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0210704 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0210371 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0208806 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0208151 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.107148 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0896655 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0853704 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0825387 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0755306 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0723887 |
| OSMR | oncostatin M receptor | -0.070641 |
| NRG1 | neuregulin 1 | -0.0598036 |
| GLCCI1 | glucocorticoid induced 1 | -0.0596937 |
| CDH13 | cadherin 13 | -0.0581722 |
| USP34 | ubiquitin specific peptidase 34 | -0.0563739 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0507048 |
| NRP1 | neuropilin 1 | -0.0487348 |
| GPC6 | glypican 6 | -0.0475197 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0469216 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0459012 |
| VRK2 | vaccinia related kinase 2 | -0.0396918 |
| MECOM | MDS1 and EVI1 complex locus | -0.0388283 |
| MTSS1 | metastasis suppressor 1 | -0.0379072 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0370999 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0365639 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0355998 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0349858 |
| RBM39 | RNA binding motif protein 39 | -0.0348256 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0339893 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0316813 |
| ETV6 | ets variant 6 | -0.0306412 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0305419 |
| IFI44L | interferon-induced protein 44-like | -0.0294316 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.029144 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0288472 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.028755 |
| HMGA1 | high mobility group AT-hook 1 | -0.0283813 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.028115 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0280408 |
| MX2 | MX dynamin-like GTPase 2 | -0.0280029 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0277352 |
| POTEF | POTE ankyrin domain family, member F | -0.0275685 |
| NPC1 | Niemann-Pick disease, type C1 | -0.02723 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.027139 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0269445 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0267275 |
| DNER | delta/notch-like EGF repeat containing | -0.0264304 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0263819 |
| FRMD4A | FERM domain containing 4A | -0.0259923 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0255659 |
| MT2A | metallothionein 2A | -0.02538 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0250608 |
| PCNX1 | pecanex 1 | -0.0248117 |
| PRRX1 | paired related homeobox 1 | -0.0247895 |
| GOLGA4 | golgin A4 | -0.0243749 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0242902 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0241975 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0241841 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0238893 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0237363 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0234145 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0230213 |
| NAV3 | neuron navigator 3 | -0.0228379 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0227853 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0227783 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.02252 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.022517 |
| OXR1 | oxidation resistance 1 | -0.0223492 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0222332 |
| RNF149 | ring finger protein 149 | -0.0221683 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0221649 |
| SP100 | SP100 nuclear antigen | -0.0218543 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0217581 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0216031 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0214242 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0213324 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0212131 |
| HMGA2 | high mobility group AT-hook 2 | -0.0209971 |
| TMEM165 | transmembrane protein 165 | -0.0209894 |
| CDK17 | cyclin-dependent kinase 17 | -0.0209597 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0208323 |
| CCDC91 | coiled-coil domain containing 91 | -0.0206042 |
| TCF12 | transcription factor 12 | -0.0202277 |
| RUNX2 | runt-related transcription factor 2 | -0.020217 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.020103 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0199769 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0198663 |
| PFN1 | profilin 1 | -0.0197616 |
| PHF14 | PHD finger protein 14 | -0.0196647 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0195439 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0195425 |
| ZNF804A | zinc finger protein 804A | -0.0194549 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0193641 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0192995 |
| RPS19 | ribosomal protein S19 | -0.0191996 |
| IFI44 | interferon-induced protein 44 | -0.0189299 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0185018 |
| BNC2 | basonuclin 2 | -0.0184638 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0184406 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0184151 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0182915 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0182618 |
| VMP1 | vacuole membrane protein 1 | -0.0181044 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.018085 |
