| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.149932 |
| IGF1R | insulin-like growth factor 1 receptor | 0.100927 |
| RAD51B | RAD51 paralog B | 0.0907698 |
| TENM3 | teneurin transmembrane protein 3 | 0.0893549 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.082991 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0786522 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0778443 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0745722 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0671874 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0667178 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0665495 |
| PDE8A | phosphodiesterase 8A | 0.0659285 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0646643 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0642014 |
| ATOSA | atos homolog A | 0.0640208 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0621979 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0596737 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0593703 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0587751 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0572223 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0558886 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0555991 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.055376 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0547314 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.053954 |
| DSG2 | desmoglein 2 | 0.0532373 |
| ANO6 | anoctamin 6 | 0.0532351 |
| MTAP | methylthioadenosine phosphorylase | 0.0525407 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0524007 |
| TXNIP | thioredoxin interacting protein | 0.0523261 |
| CDK13 | cyclin-dependent kinase 13 | 0.0500503 |
| ABHD17C | abhydrolase domain containing 17C | 0.0487866 |
| PGK1 | phosphoglycerate kinase 1 | 0.0486566 |
| CMIP | c-Maf inducing protein | 0.0465652 |
| MXD1 | MAX dimerization protein 1 | 0.0457132 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0453669 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0449756 |
| IRF6 | interferon regulatory factor 6 | 0.0447525 |
| RUNX1 | runt-related transcription factor 1 | 0.0439571 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0437418 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0432478 |
| MYO1E | myosin IE | 0.0425331 |
| ARRDC3 | arrestin domain containing 3 | 0.0425315 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0416143 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0410229 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | 0.0408182 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0405107 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0402214 |
| TUSC3 | tumor suppressor candidate 3 | 0.0400448 |
| DSPP | dentin sialophosphoprotein | 0.0398829 |
| DENND1A | DENN/MADD domain containing 1A | 0.0398565 |
| OGA | O-GlcNAcase | 0.0397806 |
| CERT1 | ceramide transporter 1 | 0.0396766 |
| CREBRF | CREB3 regulatory factor | 0.0389347 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0389061 |
| DUSP10 | dual specificity phosphatase 10 | 0.038383 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0383729 |
| TUT4 | terminal uridylyl transferase 4 | 0.0382774 |
| CDK14 | cyclin-dependent kinase 14 | 0.0382613 |
| FOXO3 | forkhead box O3 | 0.0379569 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.037314 |
| RYBP | RING1 and YY1 binding protein | 0.0372216 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0369195 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0364662 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.036403 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0363248 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0358881 |
| NEBL | nebulette | 0.0355177 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0354895 |
| CDK19 | cyclin-dependent kinase 19 | 0.0348572 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0348316 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0347686 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0344 |
| BPTF | bromodomain PHD finger transcription factor | 0.0341291 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0338434 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0335319 |
| CDYL | chromodomain protein, Y-like | 0.0332713 |
| FAT1 | FAT atypical cadherin 1 | 0.0330428 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0328655 |
| PCGF5 | polycomb group ring finger 5 | 0.0328536 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0328031 |
| PLS3 | plastin 3 | 0.0326964 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0326418 |
| STOX2 | storkhead box 2 | 0.032611 |
| NCKAP1 | NCK-associated protein 1 | 0.0325986 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.032362 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0322996 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0321524 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.031981 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0319777 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.0319652 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0318635 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0316729 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0312701 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0310397 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0309841 |
| CUL4A | cullin 4A | 0.0308388 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0308353 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0307835 |
| CALR | calreticulin | 0.0306898 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124778 |
| VIM | vimentin | -0.103274 |
| KRT17 | keratin 17, type I | -0.0987509 |
| TMSB10 | thymosin beta 10 | -0.0971356 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0946344 |
| STC1 | stanniocalcin 1 | -0.0935119 |
| LMO7 | LIM domain 7 | -0.0903257 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0893716 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0802214 |
| PTMA | prothymosin, alpha | -0.0760497 |
| RPS6 | ribosomal protein S6 | -0.0758369 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0757248 |
| SPAG9 | sperm associated antigen 9 | -0.0707201 |
| MORF4L2 | mortality factor 4 like 2 | -0.0700402 |
| FN1 | fibronectin 1 | -0.0672689 |
| LSAMP | limbic system-associated membrane protein | -0.0606928 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0585856 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0563218 |
| EGR1 | early growth response 1 | -0.0562748 |
| GOLGA4 | golgin A4 | -0.0555211 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0551002 |
| PARD3 | par-3 family cell polarity regulator | -0.0549477 |
| POTEF | POTE ankyrin domain family, member F | -0.054895 |
| TPM4 | tropomyosin 4 | -0.0547881 |
| FTL | ferritin, light polypeptide | -0.054157 |
| TJP1 | tight junction protein 1 | -0.053289 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0528132 |
| ASPH | aspartate beta-hydroxylase | -0.0521215 |
| GPC6 | glypican 6 | -0.051948 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0505681 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0500039 |
| RPS16 | ribosomal protein S16 | -0.0466324 |
| S100A9 | S100 calcium binding protein A9 | -0.0461435 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0460908 |
| PDE10A | phosphodiesterase 10A | -0.0460269 |
| MT2A | metallothionein 2A | -0.0453878 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0439265 |
| RPL31 | ribosomal protein L31 | -0.0434719 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0434061 |
| INHBA | inhibin, beta A | -0.0433676 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0432598 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0426632 |
| MUC16 | mucin 16, cell surface associated | -0.0426563 |
| EGFR | epidermal growth factor receptor | -0.0424081 |
| ANXA2 | annexin A2 | -0.0423824 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0414681 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0410018 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0405526 |
| RPL12 | ribosomal protein L12 | -0.0400418 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.039855 |
| RPL35A | ribosomal protein L35a | -0.0379767 |
| FOXP1 | forkhead box P1 | -0.037922 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0377861 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0376673 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.037539 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0374827 |
| RNF145 | ring finger protein 145 | -0.0374253 |
| MAP7 | microtubule-associated protein 7 | -0.0374042 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0371797 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0371484 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0367761 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0363312 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0360343 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.035981 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0355227 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.03539 |
| ENO1 | enolase 1, (alpha) | -0.0353276 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0351491 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0349277 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0345436 |
| TXNRD1 | thioredoxin reductase 1 | -0.0340864 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0339894 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0338896 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0338271 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0336972 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0336114 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0329342 |
| NDRG1 | N-myc downstream regulated 1 | -0.0327748 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0323207 |
| ARF4 | ADP-ribosylation factor 4 | -0.0323056 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0323017 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0322639 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0322301 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0322186 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0321608 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0320635 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0320563 |
| CCDC88A | coiled-coil domain containing 88A | -0.0319671 |
| GNAS | GNAS complex locus | -0.0318779 |
| MED13 | mediator complex subunit 13 | -0.0316338 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0316095 |
| MSN | moesin | -0.0315453 |
| SQSTM1 | sequestosome 1 | -0.0314476 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0313608 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0308277 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0305227 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0303206 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0301801 |
| RORA | RAR-related orphan receptor A | -0.0299851 |
| RPL19 | ribosomal protein L19 | -0.0298324 |
