| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.207145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.205213 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.171121 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.10241 |
| MCL1 | myeloid cell leukemia 1 | 0.100918 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0987523 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0969777 |
| INTS6 | integrator complex subunit 6 | 0.0851589 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0846807 |
| GOLGB1 | golgin B1 | 0.0775095 |
| TPM3 | tropomyosin 3 | 0.0765253 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.075064 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0688367 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0652294 |
| PCBP2 | poly(rC) binding protein 2 | 0.0639572 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0606077 |
| BRD2 | bromodomain containing 2 | 0.0601878 |
| COPA | coatomer protein complex, subunit alpha | 0.0570312 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0540347 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0535678 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0535516 |
| KRT18 | keratin 18, type I | 0.0526608 |
| CANX | calnexin | 0.052286 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0521329 |
| HOMER1 | homer scaffolding protein 1 | 0.0505048 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0486442 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0483135 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0482077 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0479673 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0467823 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0465508 |
| JMJD1C | jumonji domain containing 1C | 0.0464533 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0450108 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0447357 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0442056 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.044169 |
| CRY1 | cryptochrome circadian clock 1 | 0.0437723 |
| AEBP2 | AE binding protein 2 | 0.0418221 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0401508 |
| YBX3 | Y box binding protein 3 | 0.0395647 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0394173 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0390883 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.039073 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0389522 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0388103 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0384736 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0383829 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.038082 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0372676 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0369195 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0357655 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.035656 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0355957 |
| CALR | calreticulin | 0.0347805 |
| ATF6 | activating transcription factor 6 | 0.0346096 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0345356 |
| RPS8 | ribosomal protein S8 | 0.0343472 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.034136 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0340938 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0339229 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0338628 |
| LRRC23 | leucine rich repeat containing 23 | 0.0338568 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0334307 |
| MORF4L2 | mortality factor 4 like 2 | 0.0329157 |
| YBX1 | Y box binding protein 1 | 0.0325107 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.031863 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0316757 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0313549 |
| TLN1 | talin 1 | 0.0312798 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0311061 |
| ENO1 | enolase 1, (alpha) | 0.0309562 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0306412 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0305568 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0302326 |
| CLTC | clathrin, heavy chain (Hc) | 0.0302026 |
| NABP1 | nucleic acid binding protein 1 | 0.029853 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0297322 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0296766 |
| CALU | calumenin | 0.0294863 |
| TPM2 | tropomyosin 2 (beta) | 0.0292297 |
| MAGEA4 | melanoma antigen family A4 | 0.0291785 |
| DST | dystonin | 0.0290132 |
| FBXO11 | F-box protein 11 | 0.0288841 |
| PYGL | phosphorylase, glycogen, liver | 0.0288537 |
| JUN | jun proto-oncogene | 0.0287587 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0286214 |
| GOLT1B | golgi transport 1B | 0.0284594 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0283812 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0283606 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0282093 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0281001 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0276788 |
| SPAG9 | sperm associated antigen 9 | 0.0274896 |
| RPL37A | ribosomal protein L37a | 0.027418 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0271378 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0270551 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0268658 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0268351 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0266537 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0265608 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.124269 |
| GRAMD1B | GRAM domain containing 1B | -0.0889656 |
| NCOA7 | nuclear receptor coactivator 7 | -0.065921 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0646324 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0591801 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0565425 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0553326 |
| DENND5B | DENN/MADD domain containing 5B | -0.0530902 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.050046 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0489988 |
| TXNRD1 | thioredoxin reductase 1 | -0.0489638 |
| OSMR | oncostatin M receptor | -0.0478004 |
| POTEF | POTE ankyrin domain family, member F | -0.0464923 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0463242 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0445321 |
| PFN1 | profilin 1 | -0.0440652 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.043481 |
| CDK17 | cyclin-dependent kinase 17 | -0.0424706 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0423876 |
| PDE10A | phosphodiesterase 10A | -0.0420217 |
| LATS2 | large tumor suppressor kinase 2 | -0.0417565 |
| EGR1 | early growth response 1 | -0.0409373 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.040264 |
| RNF213 | ring finger protein 213 | -0.0401069 |
| SBF2 | SET binding factor 2 | -0.0400337 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.039588 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.037652 |
| RYR3 | ryanodine receptor 3 | -0.0365457 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0361916 |
| VIM | vimentin | -0.0359655 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0357753 |
| HMGA2 | high mobility group AT-hook 2 | -0.0348992 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0346811 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0344803 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0339363 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.03371 |
| GNAS | GNAS complex locus | -0.0329433 |
| IGF2 | insulin-like growth factor 2 | -0.0323861 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0304984 |
| CCND1 | cyclin D1 | -0.0298769 |
| RAD51B | RAD51 paralog B | -0.0298155 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0294054 |
| TLK1 | tousled-like kinase 1 | -0.0292317 |
| PTMA | prothymosin, alpha | -0.0290441 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0289217 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0285821 |
| CBX3 | chromobox homolog 3 | -0.028196 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0278608 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0277808 |
| TMEM165 | transmembrane protein 165 | -0.0276525 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0272649 |
| PHIP | pleckstrin homology domain interacting protein | -0.0269966 |
| HLA-B | major histocompatibility complex, class I, B | -0.0267051 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0263926 |
| H1-0 | H1.0 linker histone | -0.0262423 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0258038 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0254546 |
| CLDN1 | claudin 1 | -0.0254452 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0254287 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0250168 |
| ZFR | zinc finger RNA binding protein | -0.0247024 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0245689 |
| RNF145 | ring finger protein 145 | -0.0243525 |
| RPS24 | ribosomal protein S24 | -0.0242486 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0241545 |
| TAPBP | TAP binding protein (tapasin) | -0.0241382 |
| MMP12 | matrix metallopeptidase 12 | -0.0239305 |
| RBM25 | RNA binding motif protein 25 | -0.0237808 |
| PLSCR1 | phospholipid scramblase 1 | -0.023737 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0236751 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0236476 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0234055 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0232179 |
| R3HDM1 | R3H domain containing 1 | -0.0230974 |
| THOC2 | THO complex 2 | -0.0229688 |
| PTK2 | protein tyrosine kinase 2 | -0.0229036 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.022618 |
| EGFR | epidermal growth factor receptor | -0.0225918 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.022375 |
| TPM4 | tropomyosin 4 | -0.0223063 |
| BSG | basigin (Ok blood group) | -0.0221627 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0219986 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0219585 |
| NUP155 | nucleoporin 155kDa | -0.0219523 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0218855 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0217228 |
| HMGA1 | high mobility group AT-hook 1 | -0.0217163 |
| KLHL5 | kelch-like family member 5 | -0.021689 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0216841 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0216144 |
| RFX7 | regulatory factor X, 7 | -0.0215359 |
| PMP22 | peripheral myelin protein 22 | -0.0215126 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0214487 |
| SRPK2 | SRSF protein kinase 2 | -0.0214256 |
| RPL34 | ribosomal protein L34 | -0.0214051 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0212023 |
| TUBB | tubulin, beta class I | -0.0209995 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.020954 |
| NEMF | nuclear export mediator factor | -0.0207573 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0206158 |
