| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.141146 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.114259 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103944 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0888457 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0830787 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.058219 |
| ARRDC3 | arrestin domain containing 3 | 0.0493227 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0423647 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0411111 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0392491 |
| ENO1 | enolase 1, (alpha) | 0.0376658 |
| TPM3 | tropomyosin 3 | 0.0375011 |
| RPL12 | ribosomal protein L12 | 0.0341263 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0338964 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0338095 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0316737 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0301485 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0300858 |
| NDRG1 | N-myc downstream regulated 1 | 0.029039 |
| CANX | calnexin | 0.0287862 |
| CALR | calreticulin | 0.0275996 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0269579 |
| YBX1 | Y box binding protein 1 | 0.0267935 |
| SQSTM1 | sequestosome 1 | 0.0263309 |
| RPLP0 | ribosomal protein, large, P0 | 0.025752 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0253842 |
| RPS3 | ribosomal protein S3 | 0.0238613 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0237028 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0233262 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0227206 |
| RPS12 | ribosomal protein S12 | 0.0223063 |
| PCBP2 | poly(rC) binding protein 2 | 0.0221675 |
| RPL7 | ribosomal protein L7 | 0.0220518 |
| TMSB4X | thymosin beta 4, X-linked | 0.0220095 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0218445 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0217613 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0211072 |
| SGMS2 | sphingomyelin synthase 2 | 0.0210441 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0200293 |
| FAM13A | family with sequence similarity 13, member A | 0.0198338 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.019486 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0193211 |
| ADM | adrenomedullin | 0.0190054 |
| RPL8 | ribosomal protein L8 | 0.0189934 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0188123 |
| HMGB2 | high mobility group box 2 | 0.0187107 |
| MSN | moesin | 0.0185536 |
| KRT18 | keratin 18, type I | 0.0181945 |
| ANXA1 | annexin A1 | 0.0181596 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0181448 |
| TJP1 | tight junction protein 1 | 0.0181348 |
| S100A6 | S100 calcium binding protein A6 | 0.0179849 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0179038 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0178607 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0176724 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0176086 |
| LDHA | lactate dehydrogenase A | 0.0172713 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0172514 |
| SON | SON DNA binding protein | 0.0170517 |
| KIAA1217 | KIAA1217 | 0.0166417 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0166388 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0165815 |
| BRD2 | bromodomain containing 2 | 0.0165115 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0163676 |
| LAMC2 | laminin, gamma 2 | 0.0160164 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.015591 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0153703 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0151853 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.015056 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0150301 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.015028 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0149889 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.014829 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0145212 |
| RPS2 | ribosomal protein S2 | 0.0145187 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.014446 |
| RPL18 | ribosomal protein L18 | 0.0143931 |
| SDC4 | syndecan 4 | 0.0143556 |
| KRT19 | keratin 19, type I | 0.014335 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0139144 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0137201 |
| STEAP4 | STEAP family member 4 | 0.0136908 |
| UBC | ubiquitin C | 0.0136 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0134945 |
| DTNA | dystrobrevin, alpha | 0.0134768 |
| JUN | jun proto-oncogene | 0.0132704 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0132674 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0132553 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0128336 |
| HDAC9 | histone deacetylase 9 | 0.0128032 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0127651 |
| TAGLN2 | transgelin 2 | 0.0124267 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0123568 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0123088 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0121666 |
| MLF1 | myeloid leukemia factor 1 | 0.0119633 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0119514 |
| FHIT | fragile histidine triad | 0.0118488 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0117085 |
| DSPP | dentin sialophosphoprotein | 0.0116861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.147504 |
| PTMA | prothymosin, alpha | -0.134247 |
| POTEF | POTE ankyrin domain family, member F | -0.107955 |
| TMSB10 | thymosin beta 10 | -0.08574 |
| ACTG1 | actin gamma 1 | -0.0755712 |
| FN1 | fibronectin 1 | -0.0586735 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0526971 |
| FBXO32 | F-box protein 32 | -0.0376181 |
| CCND1 | cyclin D1 | -0.0374478 |
| LMO7 | LIM domain 7 | -0.034549 |
| TPM4 | tropomyosin 4 | -0.0335167 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0325053 |
| RPL31 | ribosomal protein L31 | -0.0324361 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0319451 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0317255 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0316291 |
| PKM | pyruvate kinase, muscle | -0.0303678 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0293096 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0289987 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0284541 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278457 |
| ERBIN | erbb2 interacting protein | -0.0260733 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0257014 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0256467 |
| RBM39 | RNA binding motif protein 39 | -0.0256081 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0253157 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0246473 |
| S100A10 | S100 calcium binding protein A10 | -0.0245161 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0244298 |
| VIM | vimentin | -0.0244166 |
| RPL35A | ribosomal protein L35a | -0.0236907 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0235303 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.023492 |
| HLA-B | major histocompatibility complex, class I, B | -0.0233477 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0229048 |
| CD2AP | CD2-associated protein | -0.0225066 |
| GNAS | GNAS complex locus | -0.0225064 |
| MYO6 | myosin VI | -0.0215512 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0212916 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0210861 |
| RASAL2 | RAS protein activator like 2 | -0.0209936 |
| MAP4 | microtubule-associated protein 4 | -0.0209793 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0209074 |
| RBM47 | RNA binding motif protein 47 | -0.0205182 |
| RAI14 | retinoic acid induced 14 | -0.0200365 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0198434 |
| CTSD | cathepsin D | -0.0194362 |
| TMEM123 | transmembrane protein 123 | -0.0193013 |
| TMEM165 | transmembrane protein 165 | -0.0190771 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0189546 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0185572 |
| RHOA | ras homolog family member A | -0.0185074 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0183072 |
| RPS24 | ribosomal protein S24 | -0.0182144 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0178878 |
| RNF145 | ring finger protein 145 | -0.0177941 |
| FRMD5 | FERM domain containing 5 | -0.0177877 |
| H1-0 | H1.0 linker histone | -0.0177046 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0176969 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0176433 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0176299 |
| NUMB | numb homolog (Drosophila) | -0.0175707 |
| RPS29 | ribosomal protein S29 | -0.0175094 |
| HLA-A | major histocompatibility complex, class I, A | -0.0173986 |
| OGA | O-GlcNAcase | -0.0173081 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.0171539 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0171217 |
| CAVIN1 | caveolae associated protein 1 | -0.0168039 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0167968 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.016419 |
| TOP1 | topoisomerase (DNA) I | -0.016369 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0161842 |
| RPL28 | ribosomal protein L28 | -0.0160605 |
| VDAC1 | voltage-dependent anion channel 1 | -0.015903 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0157225 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0156834 |
| MSI2 | musashi RNA-binding protein 2 | -0.0154733 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0152039 |
| RPS23 | ribosomal protein S23 | -0.0151013 |
| SRPK2 | SRSF protein kinase 2 | -0.0150901 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0149423 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0147819 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0147601 |
| LAMB3 | laminin, beta 3 | -0.0146803 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0145914 |
| ZNF207 | zinc finger protein 207 | -0.0144093 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0143923 |
| CUX1 | cut-like homeobox 1 | -0.0143585 |
| SLC38A1 | solute carrier family 38, member 1 | -0.014323 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0143119 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0143035 |
| FBXO34 | F-box protein 34 | -0.0142991 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0142378 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0142061 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0140577 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0140554 |
| RNF213 | ring finger protein 213 | -0.014044 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0139419 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | -0.0138124 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0137232 |
