| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.14138 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.120538 |
| EGR1 | early growth response 1 | 0.0948501 |
| EXT1 | exostosin glycosyltransferase 1 | 0.093009 |
| SPAG9 | sperm associated antigen 9 | 0.0927435 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0926468 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0754103 |
| LMO7 | LIM domain 7 | 0.0725173 |
| JUN | jun proto-oncogene | 0.0720074 |
| LYST | lysosomal trafficking regulator | 0.0618117 |
| RPL27A | ribosomal protein L27a | 0.061634 |
| MYO1E | myosin IE | 0.0596818 |
| RPL8 | ribosomal protein L8 | 0.0589622 |
| FTL | ferritin, light polypeptide | 0.0576521 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0555183 |
| RPL5 | ribosomal protein L5 | 0.0492362 |
| EZR | ezrin | 0.0488925 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0486664 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0470129 |
| RPS3 | ribosomal protein S3 | 0.0464053 |
| STC1 | stanniocalcin 1 | 0.0461912 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0458791 |
| SMAD3 | SMAD family member 3 | 0.0457763 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0456943 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0444967 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0441207 |
| INTS6 | integrator complex subunit 6 | 0.0431195 |
| RPS23 | ribosomal protein S23 | 0.0426705 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0415244 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0410213 |
| RPL35A | ribosomal protein L35a | 0.0401787 |
| SFTPA2 | surfactant protein A2 | 0.0400671 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0398256 |
| FNIP1 | folliculin interacting protein 1 | 0.0380459 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0379146 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.037434 |
| NCAM1 | neural cell adhesion molecule 1 | 0.036879 |
| PKM | pyruvate kinase, muscle | 0.0367331 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.035023 |
| SLTM | SAFB-like, transcription modulator | 0.0346184 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0342045 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0339906 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0335678 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0323029 |
| FAT1 | FAT atypical cadherin 1 | 0.0321546 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0319945 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0316457 |
| HLA-B | major histocompatibility complex, class I, B | 0.0316134 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0312136 |
| RPLP1 | ribosomal protein, large, P1 | 0.0310411 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0303398 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0297209 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.029519 |
| RPS12 | ribosomal protein S12 | 0.0294849 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0293785 |
| S100A6 | S100 calcium binding protein A6 | 0.0291435 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0291359 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0286733 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0281945 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0280751 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0279703 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0277247 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0276675 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0273491 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0269856 |
| GNAS | GNAS complex locus | 0.0269024 |
| RPL15 | ribosomal protein L15 | 0.0268995 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.026526 |
| FBXO11 | F-box protein 11 | 0.0257116 |
| AREG | amphiregulin | 0.0257064 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0256902 |
| RTN4 | reticulon 4 | 0.0235862 |
| LDHA | lactate dehydrogenase A | 0.0231999 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0228756 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0223047 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0210273 |
| RPS8 | ribosomal protein S8 | 0.0209981 |
| PGK1 | phosphoglycerate kinase 1 | 0.0209924 |
| B2M | beta-2-microglobulin | 0.0209703 |
| VCL | vinculin | 0.0203614 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.019746 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0184924 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0181549 |
| MT2A | metallothionein 2A | 0.0176594 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0173516 |
| MSI2 | musashi RNA-binding protein 2 | 0.0168309 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0165362 |
| JMJD1C | jumonji domain containing 1C | 0.0164783 |
| PRELID2 | PRELI domain containing 2 | 0.0164124 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0161797 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0160298 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0159433 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0157123 |
| SBF2 | SET binding factor 2 | 0.0156708 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0142889 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0141086 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0136701 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0133286 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.012652 |
| TXNRD1 | thioredoxin reductase 1 | 0.0114317 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | -0.129943 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0869494 |
| VIM | vimentin | -0.0866635 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0777682 |
| PRKCA | protein kinase C, alpha | -0.0762991 |
| EFNA5 | ephrin-A5 | -0.0749048 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0739872 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0691567 |
| NF1 | neurofibromin 1 | -0.0691041 |
| PDE10A | phosphodiesterase 10A | -0.0656527 |
| MYOF | myoferlin | -0.064133 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0639185 |
| VMP1 | vacuole membrane protein 1 | -0.0607086 |
| PTMA | prothymosin, alpha | -0.0583713 |
| FN1 | fibronectin 1 | -0.0563327 |
| ASPH | aspartate beta-hydroxylase | -0.0530647 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0501004 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0491569 |
| PCBP2 | poly(rC) binding protein 2 | -0.0480535 |
| PARD3 | par-3 family cell polarity regulator | -0.0468939 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0459761 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0435009 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0434111 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0430349 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0411301 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0407024 |
| FLNB | filamin B, beta | -0.0403369 |
| GOLGA4 | golgin A4 | -0.0393084 |
| FAM13A | family with sequence similarity 13, member A | -0.038645 |
| ANXA2 | annexin A2 | -0.0375665 |
| CDH13 | cadherin 13 | -0.0368464 |
| FHIT | fragile histidine triad | -0.0364239 |
| MATR3 | matrin 3 | -0.035022 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0344074 |
| TMSB10 | thymosin beta 10 | -0.0338581 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0337826 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0324756 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0312854 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0310507 |
| PRRC2C | proline-rich coiled-coil 2C | -0.030704 |
| HELZ | helicase with zinc finger | -0.0297728 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0297228 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0294471 |
| ATP11A | ATPase, class VI, type 11A | -0.0291314 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0274753 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0274016 |
| PTK2 | protein tyrosine kinase 2 | -0.0268191 |
| NDRG1 | N-myc downstream regulated 1 | -0.0264864 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0263244 |
| ITGA6 | integrin, alpha 6 | -0.026151 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0260747 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0252028 |
| MED13L | mediator complex subunit 13-like | -0.0250311 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0247281 |
| RPS19 | ribosomal protein S19 | -0.0246503 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.023989 |
| RPL31 | ribosomal protein L31 | -0.0235764 |
| RORA | RAR-related orphan receptor A | -0.0235676 |
| YAP1 | Yes-associated protein 1 | -0.0233651 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0233529 |
| OGA | O-GlcNAcase | -0.0227233 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0216563 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0198601 |
| ATXN1 | ataxin 1 | -0.0185363 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0168501 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0163748 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0159055 |
| MYO10 | myosin X | -0.013854 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0126658 |
| CANX | calnexin | -0.012586 |
| RPL37 | ribosomal protein L37 | -0.0116732 |
| DTNA | dystrobrevin, alpha | -0.0113371 |
| HMGA2 | high mobility group AT-hook 2 | -0.0113099 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0107905 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0105342 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0103209 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0101277 |
| ENO1 | enolase 1, (alpha) | -0.00874777 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00840088 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.00756764 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0067885 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.00663703 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.00576445 |
| RPL12 | ribosomal protein L12 | -0.00457737 |
| LAMC2 | laminin, gamma 2 | -0.0044829 |
| RPS13 | ribosomal protein S13 | -0.00438056 |
| AHNAK | AHNAK nucleoprotein | -0.00383583 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.00343663 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00319904 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00314345 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00286337 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.00281601 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00271381 |
| RPS6 | ribosomal protein S6 | -0.00221973 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.00199791 |
| RPL7 | ribosomal protein L7 | -0.0016417 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.00148807 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00117059 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -7.331E-4 |
| ARHGAP26 | Rho GTPase activating protein 26 | -6.20112E-4 |
