| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CENPF | centromere protein F, 350/400kDa | 0.108203 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.10358 |
| MKI67 | marker of proliferation Ki-67 | 0.0912632 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0908258 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0855644 |
| RPS8 | ribosomal protein S8 | 0.0849371 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0841101 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0769097 |
| COL3A1 | collagen, type III, alpha 1 | 0.0759873 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0748486 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0673437 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0649956 |
| RPS6 | ribosomal protein S6 | 0.0639288 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0623165 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0622749 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0599034 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0571175 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0564502 |
| CENPE | centromere protein E, 312kDa | 0.0535998 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0520336 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.04993 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0487177 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0461411 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0453701 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0449279 |
| COL5A2 | collagen, type V, alpha 2 | 0.0444205 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0444085 |
| PCDH9 | protocadherin 9 | 0.0443377 |
| DST | dystonin | 0.043929 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0429689 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0429549 |
| ANXA1 | annexin A1 | 0.0427611 |
| CDH19 | cadherin 19, type 2 | 0.0426482 |
| FOXP2 | forkhead box P2 | 0.0424485 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0422586 |
| RPLP0 | ribosomal protein, large, P0 | 0.0421782 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0409321 |
| RPS12 | ribosomal protein S12 | 0.0404216 |
| VIM | vimentin | 0.0392153 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0385379 |
| JMJD1C | jumonji domain containing 1C | 0.038261 |
| COL1A2 | collagen, type I, alpha 2 | 0.0380064 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0366078 |
| GANAB | glucosidase, alpha; neutral AB | 0.0364414 |
| MCL1 | myeloid cell leukemia 1 | 0.0360973 |
| RPL37 | ribosomal protein L37 | 0.0359434 |
| ENO1 | enolase 1, (alpha) | 0.0350846 |
| CCNA2 | cyclin A2 | 0.0347453 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0346915 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0343719 |
| DUSP6 | dual specificity phosphatase 6 | 0.0337761 |
| NFIA | nuclear factor I/A | 0.0335019 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0331485 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0329184 |
| GPC6 | glypican 6 | 0.0317645 |
| PGK1 | phosphoglycerate kinase 1 | 0.0314411 |
| SGO2 | shugoshin 2 | 0.0314386 |
| TPR | translocated promoter region, nuclear basket protein | 0.0311603 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.031022 |
| ADAR | adenosine deaminase, RNA-specific | 0.0310003 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0307223 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0302162 |
| TEX11 | testis expressed 11 | 0.0300831 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0300766 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0297934 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0297877 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0297127 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0291671 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0291549 |
| PDGFC | platelet derived growth factor C | 0.0291171 |
| CLTC | clathrin, heavy chain (Hc) | 0.0288826 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.028819 |
| ZNF609 | zinc finger protein 609 | 0.0288119 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.0287533 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0285014 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0284827 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0284574 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0282511 |
| RPL35A | ribosomal protein L35a | 0.0281364 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.028053 |
| ACTG1 | actin gamma 1 | 0.0279136 |
| RPL26 | ribosomal protein L26 | 0.0279092 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0278 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0277891 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0277835 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0277247 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0277044 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.027618 |
| B2M | beta-2-microglobulin | 0.0275622 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0275589 |
| ASPH | aspartate beta-hydroxylase | 0.0273554 |
| UTRN | utrophin | 0.0272445 |
| RPS2 | ribosomal protein S2 | 0.0271123 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.027063 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0270232 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0269912 |
| CALR | calreticulin | 0.0269582 |
| MYO9A | myosin IXA | 0.0269008 |
| RPL7 | ribosomal protein L7 | 0.0262771 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0260071 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.27229 |
| TMSB10 | thymosin beta 10 | -0.134807 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.100218 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0976085 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0954772 |
| POTEF | POTE ankyrin domain family, member F | -0.0763744 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0637865 |
| NTM | neurotrimin | -0.0632229 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0596912 |
| UBC | ubiquitin C | -0.0589965 |
| PLPP1 | phospholipid phosphatase 1 | -0.0551326 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0546993 |
| HDAC9 | histone deacetylase 9 | -0.053504 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0524081 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.050545 |
| LRRC4C | leucine rich repeat containing 4C | -0.0503698 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0499856 |
| MEIS2 | Meis homeobox 2 | -0.0470048 |
| PRR16 | proline rich 16 | -0.0466945 |
| GNAS | GNAS complex locus | -0.0448927 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0447945 |
| RHEB | Ras homolog enriched in brain | -0.0445151 |
| SRPK2 | SRSF protein kinase 2 | -0.0435315 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0422621 |
| ACTN4 | actinin, alpha 4 | -0.0410544 |
| THBS1 | thrombospondin 1 | -0.0409424 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0402751 |
| YAP1 | Yes-associated protein 1 | -0.0378111 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0377356 |
| RTN4 | reticulon 4 | -0.0377049 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0371992 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0355343 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0353192 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0351403 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0347949 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0341454 |
| EMP1 | epithelial membrane protein 1 | -0.0338156 |
| SET | SET nuclear proto-oncogene | -0.0334555 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | -0.0332256 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0331751 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0329577 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0321372 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0321036 |
| S100A10 | S100 calcium binding protein A10 | -0.031286 |
| NXN | nucleoredoxin | -0.0309394 |
| SHROOM3 | shroom family member 3 | -0.0307009 |
| HMGA1 | high mobility group AT-hook 1 | -0.0302732 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.029737 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.029718 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0296599 |
| NOP58 | NOP58 ribonucleoprotein | -0.029659 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0295452 |
| MEF2A | myocyte enhancer factor 2A | -0.0293462 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.029241 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0281721 |
| CD2AP | CD2-associated protein | -0.0279628 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0277312 |
| CAPNS1 | calpain, small subunit 1 | -0.0276278 |
| MPG | N-methylpurine-DNA glycosylase | -0.0274068 |
| RCOR1 | REST corepressor 1 | -0.0272818 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0270735 |
| USP3 | ubiquitin specific peptidase 3 | -0.0269923 |
| GAB2 | GRB2-associated binding protein 2 | -0.0269201 |
| VGLL3 | vestigial-like family member 3 | -0.026777 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0264925 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0261648 |
| GJD3 | gap junction protein, delta 3, 31.9kDa | -0.0259369 |
| NRG1 | neuregulin 1 | -0.0259161 |
| RNF145 | ring finger protein 145 | -0.0257624 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.025687 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0256025 |
| POU2F1 | POU class 2 homeobox 1 | -0.0250979 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0250795 |
| NPR2 | natriuretic peptide receptor 2 | -0.0247958 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0246572 |
| MTCL1 | microtubule crosslinking factor 1 | -0.0246351 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0246229 |
| ZNF207 | zinc finger protein 207 | -0.0245759 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0243491 |
| FBXO27 | F-box protein 27 | -0.0243415 |
| MMP1 | matrix metallopeptidase 1 | -0.0240386 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0238339 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0236929 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0232787 |
| ITGAV | integrin, alpha V | -0.0232716 |
| EP300 | E1A binding protein p300 | -0.0232451 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0232208 |
| MEMO1 | mediator of cell motility 1 | -0.0230372 |
| PFN1 | profilin 1 | -0.0229343 |
| DMD | dystrophin | -0.0228232 |
| WDR43 | WD repeat domain 43 | -0.0224468 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | -0.0221453 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0221208 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0220568 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0220031 |
| RAI1 | retinoic acid induced 1 | -0.0218113 |
| FLNA | filamin A, alpha | -0.0216939 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0213901 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0211523 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0211452 |
