| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.175258 |
| STC1 | stanniocalcin 1 | 0.138436 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.130967 |
| COL6A3 | collagen, type VI, alpha 3 | 0.108358 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0918435 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0916135 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0881342 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0863233 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0860564 |
| CD44 | CD44 molecule (Indian blood group) | 0.0847085 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0843326 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0826192 |
| CANX | calnexin | 0.0770862 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0756889 |
| HLA-B | major histocompatibility complex, class I, B | 0.0727928 |
| CALU | calumenin | 0.0716842 |
| KYNU | kynureninase | 0.070764 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0696454 |
| FTL | ferritin, light polypeptide | 0.0677736 |
| ARRDC3 | arrestin domain containing 3 | 0.0666815 |
| HLA-A | major histocompatibility complex, class I, A | 0.0656328 |
| ECE1 | endothelin converting enzyme 1 | 0.0647312 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0641224 |
| IL6 | interleukin 6 | 0.0640024 |
| ENO1 | enolase 1, (alpha) | 0.0637035 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0617596 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0562363 |
| CALR | calreticulin | 0.0557952 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0557443 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.054994 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0549933 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0545242 |
| FN1 | fibronectin 1 | 0.0530509 |
| ADM | adrenomedullin | 0.0517479 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0500282 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0499351 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0486349 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0480506 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0476655 |
| PGK1 | phosphoglycerate kinase 1 | 0.0468928 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0468244 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.046333 |
| GOLGA4 | golgin A4 | 0.0442959 |
| RPS8 | ribosomal protein S8 | 0.0440574 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0439223 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0430085 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0427411 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0425627 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0421195 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.042028 |
| SQSTM1 | sequestosome 1 | 0.0416863 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0407134 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0404831 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0394918 |
| ANXA1 | annexin A1 | 0.0391874 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0367805 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0362943 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0361546 |
| POM121 | POM121 transmembrane nucleoporin | 0.0360944 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0353902 |
| ANXA2 | annexin A2 | 0.0346014 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0345193 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0343564 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0342272 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0339202 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0334633 |
| FAM13A | family with sequence similarity 13, member A | 0.0331638 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0328126 |
| SPAG9 | sperm associated antigen 9 | 0.0324403 |
| ACVR1 | activin A receptor, type I | 0.0321635 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0319264 |
| ERBIN | erbb2 interacting protein | 0.031777 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0315912 |
| YIPF5 | Yip1 domain family, member 5 | 0.0315652 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0313452 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0309091 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0307634 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0305682 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0304392 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0304364 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0301059 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0300295 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0297065 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.029514 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0291621 |
| TFG | TRK-fused gene | 0.0289061 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0288859 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0286452 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0281194 |
| MTDH | metadherin | 0.0278149 |
| ZNF395 | zinc finger protein 395 | 0.027738 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.027573 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0275567 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0274323 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0273441 |
| COL3A1 | collagen, type III, alpha 1 | 0.0272799 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.027164 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0269667 |
| PTMA | prothymosin, alpha | 0.0265274 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0264599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.088719 |
| CDH13 | cadherin 13 | -0.0797884 |
| VIM | vimentin | -0.0734122 |
| MT2A | metallothionein 2A | -0.0666549 |
| EGFR | epidermal growth factor receptor | -0.0634727 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0526366 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0504616 |
| MT1X | metallothionein 1X | -0.0500883 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0482892 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0423444 |
| NRXN3 | neurexin 3 | -0.0420836 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0419392 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.040382 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0345861 |
| EFNA5 | ephrin-A5 | -0.03355 |
| NAV1 | neuron navigator 1 | -0.0335409 |
| RTN4 | reticulon 4 | -0.0328858 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0311661 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0309099 |
| HMGA2 | high mobility group AT-hook 2 | -0.029981 |
| NBAS | neuroblastoma amplified sequence | -0.0290412 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | -0.0285624 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0276619 |
| TSPAN5 | tetraspanin 5 | -0.0274855 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0270144 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0267766 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0267137 |
| KIF16B | kinesin family member 16B | -0.0264933 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0261014 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0260312 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0259065 |
| PKM | pyruvate kinase, muscle | -0.025727 |
| RBM33 | RNA binding motif protein 33 | -0.0256742 |
| SEC24D | SEC24 family member D | -0.0255734 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.025118 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0246604 |
| RASA2 | RAS p21 protein activator 2 | -0.0246113 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | -0.0243953 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0243667 |
| PDE10A | phosphodiesterase 10A | -0.0242974 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0241859 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0241088 |
| ZNF638 | zinc finger protein 638 | -0.0241013 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.023747 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0237452 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.023661 |
| CENPF | centromere protein F, 350/400kDa | -0.0231054 |
| OGA | O-GlcNAcase | -0.0230743 |
| SEPTIN2 | septin 2 | -0.0229883 |
| KRIT1 | KRIT1, ankyrin repeat containing | -0.0229779 |
| LMNA | lamin A/C | -0.0225124 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0221009 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0219883 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0219685 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0218033 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0216531 |
| FOSL1 | FOS-like antigen 1 | -0.0216191 |
| CDK19 | cyclin-dependent kinase 19 | -0.0215693 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0215499 |
| DST | dystonin | -0.0215268 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0213643 |
| TPX2 | TPX2, microtubule-associated | -0.0213516 |
| HDLBP | high density lipoprotein binding protein | -0.0213237 |
| SMYD3 | SET and MYND domain containing 3 | -0.0212428 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0211759 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0210467 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0208304 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0207885 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0207812 |
| EGR1 | early growth response 1 | -0.0206781 |
| MYOF | myoferlin | -0.0205511 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0204314 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0202425 |
| RPAP2 | RNA polymerase II associated protein 2 | -0.0201168 |
| ECT2 | epithelial cell transforming 2 | -0.0201126 |
| TNS3 | tensin 3 | -0.0200431 |
| ATP11B | ATPase, class VI, type 11B | -0.0199838 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0199405 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.019812 |
| VEGFA | vascular endothelial growth factor A | -0.0197981 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0197558 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0196865 |
| NAV2 | neuron navigator 2 | -0.0196778 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0196199 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0196092 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0196005 |
| CD109 | CD109 molecule | -0.0195823 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0195503 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0194264 |
| ACTN4 | actinin, alpha 4 | -0.0193863 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0193024 |
| RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing | -0.0192981 |
| OSMR | oncostatin M receptor | -0.0192256 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0191842 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | -0.0190403 |
| FRMD4A | FERM domain containing 4A | -0.0190267 |
| C1D | C1D nuclear receptor corepressor | -0.0190102 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0189769 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0189726 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | -0.0188999 |
