| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ML264 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ML264_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.114448 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0881408 |
| EXT1 | exostosin glycosyltransferase 1 | 0.073774 |
| STC2 | stanniocalcin 2 | 0.0673437 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0627507 |
| NRG1 | neuregulin 1 | 0.0597879 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0593505 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.052111 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.052071 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.051433 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0487413 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0482008 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0480501 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0474807 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0466693 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0450369 |
| SQSTM1 | sequestosome 1 | 0.0439374 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0438888 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0432545 |
| INTS6 | integrator complex subunit 6 | 0.0428744 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0426275 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0412537 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0401187 |
| HMGA2 | high mobility group AT-hook 2 | 0.0399639 |
| VCL | vinculin | 0.0385884 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0352947 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0352533 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.035193 |
| CTBP2 | C-terminal binding protein 2 | 0.0339605 |
| FAT1 | FAT atypical cadherin 1 | 0.0337063 |
| SIK3 | SIK family kinase 3 | 0.0335134 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0332801 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0328706 |
| FN1 | fibronectin 1 | 0.032445 |
| SVIL | supervillin | 0.0319368 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.031853 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0315886 |
| MCL1 | myeloid cell leukemia 1 | 0.0312767 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0305501 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.030508 |
| RASAL2 | RAS protein activator like 2 | 0.0298923 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0298774 |
| AEBP2 | AE binding protein 2 | 0.0298715 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0298684 |
| ATF6 | activating transcription factor 6 | 0.0295172 |
| EMP1 | epithelial membrane protein 1 | 0.0293711 |
| AHNAK | AHNAK nucleoprotein | 0.0287073 |
| EFNA5 | ephrin-A5 | 0.0283646 |
| CRY1 | cryptochrome circadian clock 1 | 0.0278799 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0272982 |
| LOXL2 | lysyl oxidase-like 2 | 0.0267052 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0265938 |
| SEPTIN9 | septin 9 | 0.0265851 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0265045 |
| GPATCH2L | G patch domain containing 2-like | 0.0261194 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0261096 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0258783 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0254876 |
| MYOF | myoferlin | 0.0252932 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.025196 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0240975 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0236019 |
| LMNA | lamin A/C | 0.0233503 |
| GPC6 | glypican 6 | 0.0227551 |
| TUFT1 | tuftelin 1 | 0.0227514 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0220559 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0219684 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0219404 |
| SMAD3 | SMAD family member 3 | 0.0217779 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0215256 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0211314 |
| SFTPA2 | surfactant protein A2 | 0.0210489 |
| RAI14 | retinoic acid induced 14 | 0.0210015 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.020742 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0206657 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0203652 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0201612 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0199715 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0198849 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0198741 |
| TGFA | transforming growth factor, alpha | 0.0194232 |
| SGMS2 | sphingomyelin synthase 2 | 0.0194153 |
| ENO1 | enolase 1, (alpha) | 0.0193592 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0192634 |
| JUN | jun proto-oncogene | 0.0192606 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0192603 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0192519 |
| DSG2 | desmoglein 2 | 0.0190643 |
| FAM107B | family with sequence similarity 107, member B | 0.0190068 |
| PALLD | palladin, cytoskeletal associated protein | 0.0190066 |
| EZR | ezrin | 0.0189361 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0187223 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0186167 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0185661 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0185499 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0185215 |
| FAM13A | family with sequence similarity 13, member A | 0.0183893 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0183492 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.018134 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0180786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.230594 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.104044 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.1003 |
| MT2A | metallothionein 2A | -0.0849969 |
| TMSB10 | thymosin beta 10 | -0.0814453 |
| FTL | ferritin, light polypeptide | -0.0653433 |
| PTMA | prothymosin, alpha | -0.0653355 |
| VIM | vimentin | -0.0603611 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.058551 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0558502 |
| RPS6 | ribosomal protein S6 | -0.0466916 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0443721 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0431815 |
| CENPF | centromere protein F, 350/400kDa | -0.0412465 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.040531 |
| RBM25 | RNA binding motif protein 25 | -0.0387202 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0377912 |
| S100A6 | S100 calcium binding protein A6 | -0.037785 |
| RNF145 | ring finger protein 145 | -0.0376782 |
| PKM | pyruvate kinase, muscle | -0.0351229 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0350826 |
| NDRG1 | N-myc downstream regulated 1 | -0.0348388 |
| RPLP1 | ribosomal protein, large, P1 | -0.0344879 |
| TMEM165 | transmembrane protein 165 | -0.033102 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0327551 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0324571 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0318815 |
| OGA | O-GlcNAcase | -0.0297614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0297134 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0292788 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0289665 |
| HMGA1 | high mobility group AT-hook 1 | -0.0275168 |
| TXNIP | thioredoxin interacting protein | -0.027253 |
| TXNRD1 | thioredoxin reductase 1 | -0.0269744 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0269539 |
| SMOX | spermine oxidase | -0.0268612 |
| RPS19 | ribosomal protein S19 | -0.0261589 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0250704 |
| COG5 | component of oligomeric golgi complex 5 | -0.0248354 |
| COPA | coatomer protein complex, subunit alpha | -0.0243641 |
| ZNF292 | zinc finger protein 292 | -0.0241204 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.024113 |
| POTEF | POTE ankyrin domain family, member F | -0.0240622 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0239727 |
| AHR | aryl hydrocarbon receptor | -0.0236341 |
| RPS5 | ribosomal protein S5 | -0.0233737 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.022554 |
| PELO | pelota homolog (Drosophila) | -0.0216399 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0216065 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0215258 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0214349 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0214185 |
| RBM39 | RNA binding motif protein 39 | -0.0213554 |
| GNAS | GNAS complex locus | -0.021081 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0210194 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0208271 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0206542 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0205968 |
| CDC27 | cell division cycle 27 | -0.0205694 |
| NUP58 | nucleoporin 58 | -0.0204892 |
| CCNL1 | cyclin L1 | -0.0201811 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0200492 |
| PLIN2 | perilipin 2 | -0.0198545 |
| RPL23 | ribosomal protein L23 | -0.019789 |
| RPL28 | ribosomal protein L28 | -0.0196872 |
| WDR45B | WD repeat domain 45B | -0.0196643 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0196444 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0193339 |
| PFN1 | profilin 1 | -0.019294 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0192815 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0192425 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0192049 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0191871 |
| TFG | TRK-fused gene | -0.0190815 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0190697 |
| TPR | translocated promoter region, nuclear basket protein | -0.0190547 |
| RPS20 | ribosomal protein S20 | -0.0187928 |
| NKTR | natural killer cell triggering receptor | -0.0186728 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0185998 |
| SEPTIN7 | septin 7 | -0.0185051 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0183218 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0182934 |
| NEK7 | NIMA-related kinase 7 | -0.0181375 |
| HDGF | hepatoma-derived growth factor | -0.0180515 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0179106 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.017868 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0177808 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0176982 |
| RTN4 | reticulon 4 | -0.0175721 |
| MATR3 | matrin 3 | -0.0175158 |
| FAF2 | Fas associated factor family member 2 | -0.0174129 |
| RPL9 | ribosomal protein L9 | -0.0173172 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0171911 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0171678 |
| RPS24 | ribosomal protein S24 | -0.0171432 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0170862 |
| RPL32 | ribosomal protein L32 | -0.0170202 |
| RNF24 | ring finger protein 24 | -0.0168322 |
| RPLP2 | ribosomal protein, large, P2 | -0.0166184 |
| OSMR | oncostatin M receptor | -0.0166062 |
