MLH1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description mutL homolog 1|This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 4292)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MLH1
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Genes

42 co-expressed genes for MLH1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
C14ORF166 chromosome 14 open reading frame 166
CBX3 chromobox homolog 3
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CNOT1 CCR4-NOT transcription complex, subunit 1
DKC1 dyskeratosis congenita 1, dyskerin
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
FANCI Fanconi anemia, complementation group I
H2AFZ H2A histone family, member Z
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
ILF2 interleukin enhancer binding factor 2
KARS lysyl-tRNA synthetase
KNTC1 kinetochore associated 1
LRPPRC leucine-rich pentatricopeptide repeat containing
MCM3 minichromosome maintenance complex component 3
MLH1 mutL homolog 1
MRPL42 mitochondrial ribosomal protein L42
MSH2 mutS homolog 2
MSH6 mutS homolog 6
NCL nucleolin
NDC80 NDC80 kinetochore complex component
NUP107 nucleoporin 107kDa
NUP153 nucleoporin 153kDa
PA2G4 proliferation-associated 2G4, 38kDa
PTGES3 prostaglandin E synthase 3 (cytosolic)
RBBP4 retinoblastoma binding protein 4
RBMX RNA binding motif protein, X-linked
RFC4 replication factor C (activator 1) 4, 37kDa
SERBP1 SERPINE1 mRNA binding protein 1
SLBP stem-loop binding protein
SMC3 structural maintenance of chromosomes 3
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SRSF1 serine/arginine-rich splicing factor 1
SSRP1 structure specific recognition protein 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TCERG1 transcription elongation regulator 1
TCP1 t-complex 1
U2SURP U2 snRNP-associated SURP domain containing
USP1 ubiquitin specific peptidase 1