MLKL Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description mixed lineage kinase domain-like| (NCBI Entrez Gene Database, 197259)
External Link https://ncbi.nlm.nih.gov/gene/197259
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Genes

499 genes differentially expressed following the MLKL gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen 0.0168913
GNAS GNAS complex locus 0.015332
ANPEP alanyl (membrane) aminopeptidase 0.0142349
FGFR2 fibroblast growth factor receptor 2 0.0130605
RAD23B RAD23 homolog B (S. cerevisiae) 0.0126809
COL11A1 collagen, type XI, alpha 1 0.0122417
IFI6 interferon, alpha-inducible protein 6 0.0115143
NPM3 nucleophosmin/nucleoplasmin 3 0.0111058
TYMS thymidylate synthetase 0.0110878
WSB1 WD repeat and SOCS box containing 1 0.0110449
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.010883
MAGEA3 melanoma antigen family A3 0.0107069
ALOX5 arachidonate 5-lipoxygenase 0.010702
CYBRD1 cytochrome b reductase 1 0.0105598
CDC20 cell division cycle 20 0.0105014
NUSAP1 nucleolar and spindle associated protein 1 0.0104893
NMU neuromedin U 0.0101478
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0101435
LUM lumican 0.00994177
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.00993408
PCLAF PCNA clamp associated factor 0.00984985
PDE4A phosphodiesterase 4A, cAMP-specific 0.00983329
CLEC7A C-type lectin domain family 7, member A 0.00971798
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00971723
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00960147
GOLM1 golgi membrane protein 1 0.00955317
POSTN periostin, osteoblast specific factor 0.00951225
COL1A2 collagen, type I, alpha 2 0.00942323
ISG15 ISG15 ubiquitin-like modifier 0.00932458
ASPN asporin 0.00927545
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00921332
GREB1 growth regulation by estrogen in breast cancer 1 0.00911174
FKBP4 FK506 binding protein 4, 59kDa 0.00907223
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00902404
POMZP3 POM121 and ZP3 fusion 0.00898956
ADCY1 adenylate cyclase 1 (brain) 0.00897865
COL3A1 collagen, type III, alpha 1 0.00889183
RRM2 ribonucleotide reductase M2 0.00887865
CADM1 cell adhesion molecule 1 0.00878978
NLRP2 NLR family, pyrin domain containing 2 0.00877168
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.00876412
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.00873198
COL4A5 collagen, type IV, alpha 5 0.00866659
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00862397
LMNB1 lamin B1 0.00860207
PDGFC platelet derived growth factor C 0.00858139
RNF167 ring finger protein 167 0.00855902
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00848434
SPTSSA serine palmitoyltransferase, small subunit A 0.0084791
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 0.00847149
ZFP36L1 ZFP36 ring finger protein-like 1 0.00846556
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00836205
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00830732
TGFB1 transforming growth factor, beta 1 0.00828447
SLC25A46 solute carrier family 25, member 46 0.00823396
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00821767
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.00821712
COL10A1 collagen, type X, alpha 1 0.00820887
SLBP stem-loop binding protein 0.00817457
CHN2 chimerin 2 0.00812237
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00811197
RIN2 Ras and Rab interactor 2 0.008108
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.0079782
LYPLA1 lysophospholipase I 0.00796068
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00790401
CCP110 centriolar coiled coil protein 110kDa 0.00789046
ADARB1 adenosine deaminase, RNA-specific, B1 0.00786326
ZWINT ZW10 interacting kinetochore protein 0.00786238
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.00785823
MCM5 minichromosome maintenance complex component 5 0.00785222
IGFBP5 insulin-like growth factor binding protein 5 0.0078414
PCP4 Purkinje cell protein 4 0.00783647
DUT deoxyuridine triphosphatase 0.00781147
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00777816
MMP9 matrix metallopeptidase 9 0.00775274
COL6A3 collagen, type VI, alpha 3 0.00772302
HCRT hypocretin (orexin) neuropeptide precursor 0.0076614
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.00765835
ACAT2 acetyl-CoA acetyltransferase 2 0.00764121
LYZ lysozyme 0.00763886
CPE carboxypeptidase E 0.00759491
CXCL9 chemokine (C-X-C motif) ligand 9 0.00757831
CSAD cysteine sulfinic acid decarboxylase 0.00756124
ARF3 ADP-ribosylation factor 3 0.00755636
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00754534
PTK7 protein tyrosine kinase 7 (inactive) 0.0075423
F5 coagulation factor V (proaccelerin, labile factor) 0.00754184
SOCS1 suppressor of cytokine signaling 1 0.00751853
LGALS2 lectin, galactoside-binding, soluble, 2 0.00748289
PDIA3 protein disulfide isomerase family A, member 3 0.0074606
CHKB choline kinase beta 0.00745679
C2CD5 C2 calcium-dependent domain containing 5 0.00742008
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00741747
MAVS mitochondrial antiviral signaling protein 0.00740803
SETD6 SET domain containing 6 0.00737545
PON2 paraoxonase 2 0.00737399
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00736092
YAP1 Yes-associated protein 1 0.00731947
CFB complement factor B 0.00731339
FGFR3 fibroblast growth factor receptor 3 0.00729113
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00729022
CPB1 carboxypeptidase B1 (tissue) 0.0072482
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00722708
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00719937
CCNE2 cyclin E2 0.00719824
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00717261
ZBTB18 zinc finger and BTB domain containing 18 0.00717257
MEST mesoderm specific transcript 0.00716891
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00715907
COL6A1 collagen, type VI, alpha 1 0.00714536
STMN1 stathmin 1 0.00713571
ZNF43 zinc finger protein 43 0.00712762
DCT dopachrome tautomerase 0.00706696
LRRC15 leucine rich repeat containing 15 0.00705194
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.00703961
PSD3 pleckstrin and Sec7 domain containing 3 0.00702472
NIT1 nitrilase 1 0.00701253
GREM1 gremlin 1, DAN family BMP antagonist 0.00698392
SGK1 serum/glucocorticoid regulated kinase 1 0.00693826
SELENBP1 selenium binding protein 1 0.00693256
NADK NAD kinase 0.00692785
TGFB1I1 transforming growth factor beta 1 induced transcript 1 0.00692212
TMSB15A thymosin beta 15a 0.00690171
TGFBI transforming growth factor, beta-induced, 68kDa 0.00689888
HMGB2 high mobility group box 2 0.00688728
BCHE butyrylcholinesterase 0.00688669
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00687423
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00686875
PER3 period circadian clock 3 0.0068505
FBXO21 F-box protein 21 0.0068366
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00682817
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.00682153
CNPY3 canopy FGF signaling regulator 3 0.00682135
EXT1 exostosin glycosyltransferase 1 0.00680083
EFR3A EFR3 homolog A (S. cerevisiae) 0.00679396
THY1 Thy-1 cell surface antigen 0.00676525
BID BH3 interacting domain death agonist 0.00675746
BIRC2 baculoviral IAP repeat containing 2 0.00675177
EPAS1 endothelial PAS domain protein 1 0.00674097
MMP11 matrix metallopeptidase 11 0.0067341
HMGN2 high mobility group nucleosomal binding domain 2 0.00672493
LY6E lymphocyte antigen 6 complex, locus E 0.00671735
RACGAP1 Rac GTPase activating protein 1 0.00671376
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00670533
SUN1 Sad1 and UNC84 domain containing 1 0.00670242
MYO1D myosin ID 0.00669729
RTN2 reticulon 2 0.00668765
BTBD3 BTB (POZ) domain containing 3 0.00666311
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00666255
VCAM1 vascular cell adhesion molecule 1 0.00666178
PDE8A phosphodiesterase 8A 0.00664217
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00663624
NINL ninein-like 0.00662731
IQGAP2 IQ motif containing GTPase activating protein 2 0.00661761
DHFR dihydrofolate reductase 0.00659462
HIRA histone cell cycle regulator 0.0065685
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00654666
IL27RA interleukin 27 receptor, alpha 0.00653119
ARG2 arginase 2 0.0065152
GUSB glucuronidase, beta 0.00651119
BST2 bone marrow stromal cell antigen 2 0.00650928
ZBTB20 zinc finger and BTB domain containing 20 0.00650553
PSRC1 proline/serine-rich coiled-coil 1 0.00650034
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00648599
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00646919
CLDN3 claudin 3 0.00645449
BRCA1 breast cancer 1, early onset 0.00644918
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00642553
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 0.00640292
ERBIN erbb2 interacting protein 0.00640208
PHTF2 putative homeodomain transcription factor 2 0.0063472
NDUFA4 NDUFA4, mitochondrial complex associated 0.00634086
CHN1 chimerin 1 0.00633666
SALL2 spalt-like transcription factor 2 0.00632915
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00632239
RGS16 regulator of G-protein signaling 16 0.00632182
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 0.00630496
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.00630487
EPHX2 epoxide hydrolase 2, cytoplasmic 0.00629629
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00628901
ADSL adenylosuccinate lyase 0.00627508
PDAP1 PDGFA associated protein 1 0.00627291
PPT1 palmitoyl-protein thioesterase 1 0.00627204
KIF18B kinesin family member 18B 0.0062548
NUAK1 NUAK family, SNF1-like kinase, 1 0.00625108
RNF144A ring finger protein 144A 0.00624195
CNN3 calponin 3, acidic 0.00623977
NXN nucleoredoxin 0.00623653
KIF22 kinesin family member 22 0.00623212
NUPR1 nuclear protein, transcriptional regulator, 1 0.00623024
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 0.00622618
NIBAN1 niban apoptosis regulator 1 0.00621185
CBS cystathionine-beta-synthase 0.00619191
TIMP1 TIMP metallopeptidase inhibitor 1 0.00618696
EXPH5 exophilin 5 0.00617069
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00614994
RANBP1 RAN binding protein 1 0.00614607
TESK1 testis-specific kinase 1 0.00613516
MCM4 minichromosome maintenance complex component 4 0.00612586
FRY furry homolog (Drosophila) 0.00611962
UBE2C ubiquitin-conjugating enzyme E2C 0.00608141
ABAT 4-aminobutyrate aminotransferase 0.00608005
BCL7B B-cell CLL/lymphoma 7B 0.00607374
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 0.00607145
TRMT5 tRNA methyltransferase 5 0.00606735
ICOS inducible T-cell co-stimulator 0.00606066
SCARB2 scavenger receptor class B, member 2 0.00605756
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00604446
TFPI2 tissue factor pathway inhibitor 2 0.00604283
HSPB11 heat shock protein family B (small), member 11 0.00602327
HIC2 hypermethylated in cancer 2 0.00602223
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00602057
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00600995
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.00600992
AURKB aurora kinase B 0.00600382
HNMT histamine N-methyltransferase 0.00599458
ITM2B integral membrane protein 2B 0.00599155
LPAR6 lysophosphatidic acid receptor 6 0.00597958
SDF4 stromal cell derived factor 4 0.00597629
PLBD1 phospholipase B domain containing 1 0.00597533
PRDX2 peroxiredoxin 2 0.00596935
C1ORF115 chromosome 1 open reading frame 115 0.00596433
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.00595958
KIFC1 kinesin family member C1 0.00595729
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00594975
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 0.00594741
PBLD phenazine biosynthesis-like protein domain containing 0.00593388
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00592971
EDNRA endothelin receptor type A 0.00591454
SEPHS2 selenophosphate synthetase 2 0.00591278
LRRC47 leucine rich repeat containing 47 0.00590401
MT1E metallothionein 1E 0.0058864
IFI44 interferon-induced protein 44 0.00588387
CCNL2 cyclin L2 0.00587795
INSIG1 insulin induced gene 1 0.00587323
CTSA cathepsin A 0.00586928
NUP50 nucleoporin 50kDa 0.00585388
FAM120A family with sequence similarity 120A 0.00585328
ISYNA1 inositol-3-phosphate synthase 1 0.00585058
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00583053
PLCL1 phospholipase C-like 1 0.00580554
SNX5 sorting nexin 5 0.00579145
COL5A2 collagen, type V, alpha 2 0.00578315
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.00576738
DEFA4 defensin, alpha 4, corticostatin 0.00576707
LBR lamin B receptor 0.00576678
MEPCE methylphosphate capping enzyme 0.00575511
H1-0 H1.0 linker histone 0.00575158
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.00573077

decreased expression

Symbol Name Standardized Value
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -0.0143291
KRT14 keratin 14, type I -0.0139423
S100A8 S100 calcium binding protein A8 -0.0131863
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0131335
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.013009
ISG20 interferon stimulated exonuclease gene 20kDa -0.0124861
SPRR3 small proline-rich protein 3 -0.0124838
CRYAB crystallin, alpha B -0.0124339
ADM adrenomedullin -0.0123655
BHLHE41 basic helix-loop-helix family, member e41 -0.0119493
PI3 peptidase inhibitor 3, skin-derived -0.0119349
BAMBI BMP and activin membrane-bound inhibitor -0.0118742
IGFBP6 insulin-like growth factor binding protein 6 -0.0117313
RHCG Rh family, C glycoprotein -0.0117226
RCAN1 regulator of calcineurin 1 -0.0114774
FABP4 fatty acid binding protein 4, adipocyte -0.0113913
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0113634
GPX3 glutathione peroxidase 3 -0.0111068
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0109936
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.0107789
KRT13 keratin 13, type I -0.0104678
S100A9 S100 calcium binding protein A9 -0.0104361
BAALC brain and acute leukemia, cytoplasmic -0.010398
TGFBR3 transforming growth factor, beta receptor III -0.0103855
HEATR1 HEAT repeat containing 1 -0.0102459
PTHLH parathyroid hormone-like hormone -0.0101681
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.010096
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.0100782
HSPB8 heat shock 22kDa protein 8 -0.0100681
S100P S100 calcium binding protein P -0.0100438
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0099998
TRIM16 tripartite motif containing 16 -0.0099475
FERMT1 fermitin family member 1 -0.00989625
PSCA prostate stem cell antigen -0.00987527
LY6D lymphocyte antigen 6 complex, locus D -0.00978162
ADIRF adipogenesis regulatory factor -0.00970907
HOPX HOP homeobox -0.00963179
TM4SF1 transmembrane 4 L six family member 1 -0.00961247
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.00943617
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00940918
NDRG1 N-myc downstream regulated 1 -0.00936591
MALL mal, T-cell differentiation protein-like -0.00934075
KLF6 Kruppel-like factor 6 -0.00928184
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00926252
GPX2 glutathione peroxidase 2 -0.0092037
ABLIM1 actin binding LIM protein 1 -0.00919771
FAM107A family with sequence similarity 107, member A -0.00918075
FGFBP1 fibroblast growth factor binding protein 1 -0.00915291
YBX3 Y box binding protein 3 -0.00903185
MATN2 matrilin 2 -0.00899195
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.0089606
CRYBG1 crystallin beta-gamma domain containing 1 -0.00893877
TEX10 testis expressed 10 -0.00889603
S100A2 S100 calcium binding protein A2 -0.00886782
TSPAN13 tetraspanin 13 -0.00885426
PPP1R3C protein phosphatase 1, regulatory subunit 3C -0.0087597
TENT5A terminal nucleotidyltransferase 5A -0.00871877
S100A7 S100 calcium binding protein A7 -0.00868974
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 -0.00866593
FOSL1 FOS-like antigen 1 -0.00866154
TRIM29 tripartite motif containing 29 -0.00858762
KLF2 Kruppel-like factor 2 -0.00856446
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00855544
KRT6B keratin 6B, type II -0.00855011
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00854025
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00850011
PLIN3 perilipin 3 -0.00849065
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 -0.00845389
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00843194
BTG1 B-cell translocation gene 1, anti-proliferative -0.00841125
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 -0.00838064
CHRDL1 chordin-like 1 -0.00826468
SMAD3 SMAD family member 3 -0.00822785
KLK6 kallikrein-related peptidase 6 -0.00816967
LPIN1 lipin 1 -0.00816616
KRT6A keratin 6A, type II -0.00816043
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00811495
EMP1 epithelial membrane protein 1 -0.00811419
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00808689
AREG amphiregulin -0.00807374
IER3 immediate early response 3 -0.00805554
C10ORF10 chromosome 10 open reading frame 10 -0.00804151
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00803135
XPO7 exportin 7 -0.00799665
CRCT1 cysteine-rich C-terminal 1 -0.00799604
E2F2 E2F transcription factor 2 -0.00795602
PODXL podocalyxin-like -0.00792474
RUNX1 runt-related transcription factor 1 -0.00791623
DDIT3 DNA-damage-inducible transcript 3 -0.00789002
TIMP4 TIMP metallopeptidase inhibitor 4 -0.00788995
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00786896
ACTC1 actin, alpha, cardiac muscle 1 -0.00786162
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00782301
CSTA cystatin A (stefin A) -0.00779338
ANXA2P2 annexin A2 pseudogene 2 -0.00777654
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.0077513
SYNM synemin, intermediate filament protein -0.00772896
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.00771561
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00768372
BPGM 2,3-bisphosphoglycerate mutase -0.00763572
EHD3 EH-domain containing 3 -0.00758737
KRT7 keratin 7, type II -0.0075859
AQP3 aquaporin 3 (Gill blood group) -0.00756074
CD59 CD59 molecule, complement regulatory protein -0.00755253
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00750047
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00749987
MAP7 microtubule-associated protein 7 -0.00746989
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.00746739
CFD complement factor D (adipsin) -0.00746724
RADX RPA1 related single stranded DNA binding protein, X-linked -0.00744361
LAMC2 laminin, gamma 2 -0.00743447
CGRRF1 cell growth regulator with ring finger domain 1 -0.00741174
IVL involucrin -0.00738216
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.0073773
TCTN2 tectonic family member 2 -0.0073705
KRT5 keratin 5, type II -0.00733651
PUF60 poly-U binding splicing factor 60KDa -0.00731866
TRAF3IP2 TRAF3 interacting protein 2 -0.00731385
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00729488
ADGRG6 adhesion G protein-coupled receptor G6 -0.00729428
MIA melanoma inhibitory activity -0.00727593
CLTB clathrin, light chain B -0.00725632
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00724346
NCK1 NCK adaptor protein 1 -0.00721976
LAMA2 laminin, alpha 2 -0.00716943
CLCA4 chloride channel accessory 4 -0.00714815
CLDN10 claudin 10 -0.00712578
SLC35G2 solute carrier family 35, member G2 -0.00712397
DSG3 desmoglein 3 -0.00712276
KRT81 keratin 81, type II -0.00708035
TGFA transforming growth factor, alpha -0.00707588
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00704616
KANK1 KN motif and ankyrin repeat domains 1 -0.00703405
SPRR1A small proline-rich protein 1A -0.00703079
S100A10 S100 calcium binding protein A10 -0.00702527
RBM34 RNA binding motif protein 34 -0.00696399
PMP2 peripheral myelin protein 2 -0.00694002
ANXA2 annexin A2 -0.00693435
POPDC3 popeye domain containing 3 -0.00691864
RPL36AL ribosomal protein L36a-like -0.00691705
IER3IP1 immediate early response 3 interacting protein 1 -0.0069129
BEX1 brain expressed, X-linked 1 -0.00689394
HSPA2 heat shock 70kDa protein 2 -0.00689209
HOMER1 homer scaffolding protein 1 -0.00688739
DHRS9 dehydrogenase/reductase (SDR family) member 9 -0.00687147
TMPRSS11D transmembrane protease, serine 11D -0.00685012
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00683752
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00683692
EAF2 ELL associated factor 2 -0.00682587
STON1 stonin 1 -0.00682166
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00680399
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00679109
FEM1C fem-1 homolog c (C. elegans) -0.00678853
KLK11 kallikrein-related peptidase 11 -0.00678489
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -0.00678096
SRPX sushi-repeat containing protein, X-linked -0.00677055
IL15 interleukin 15 -0.006764
MMP10 matrix metallopeptidase 10 -0.00675655
VLDLR very low density lipoprotein receptor -0.00675621
MEN1 multiple endocrine neoplasia I -0.00675531
EMX2 empty spiracles homeobox 2 -0.00674983
PALLD palladin, cytoskeletal associated protein -0.00674666
MED6 mediator complex subunit 6 -0.00671778
CLCA2 chloride channel accessory 2 -0.00669246
WSB2 WD repeat and SOCS box containing 2 -0.00668074
SPRY2 sprouty homolog 2 (Drosophila) -0.00659886
RRAGD Ras-related GTP binding D -0.00658551
WWTR1 WW domain containing transcription regulator 1 -0.00658289
PDE4B phosphodiesterase 4B, cAMP-specific -0.00658195
ECPAS Ecm29 proteasome adaptor and scaffold -0.00657876
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00656229
GMDS GDP-mannose 4,6-dehydratase -0.00655503
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00655376
TSLIG3A tRNA splicing ligase complex subunit 3A -0.00651703
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00649823
KLK13 kallikrein-related peptidase 13 -0.00649395
CAST calpastatin -0.00646812
KLK12 kallikrein-related peptidase 12 -0.00644563
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -0.00643382
NEBL nebulette -0.00643121
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -0.00642746
LAMB3 laminin, beta 3 -0.0064267
GYPC glycophorin C (Gerbich blood group) -0.0064227
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00641342
AKR1C2 aldo-keto reductase family 1, member C2 -0.00641175
SLC38A6 solute carrier family 38, member 6 -0.00640967
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -0.00640399
CALCA calcitonin-related polypeptide alpha -0.00638574
TMPRSS11E transmembrane protease, serine 11E -0.00636518
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00636221
KRT19 keratin 19, type I -0.00634855
VAMP8 vesicle-associated membrane protein 8 -0.00634611
VPREB1 pre-B lymphocyte 1 -0.00634263
CLU clusterin -0.00634025
TNNC1 troponin C type 1 (slow) -0.00632795
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00632393
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00632136
PROM1 prominin 1 -0.0063017
OPTN optineurin -0.00629628
TDRD7 tudor domain containing 7 -0.00629264
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00628985
AKAP12 A kinase (PRKA) anchor protein 12 -0.00627584
CRNN cornulin -0.00627575
CD34 CD34 molecule -0.00624551
KLC1 kinesin light chain 1 -0.00623909
KLK7 kallikrein-related peptidase 7 -0.00623286
AHNAK AHNAK nucleoprotein -0.00622659
FHL2 four and a half LIM domains 2 -0.00622654
KRT15 keratin 15, type I -0.00620102
KLF5 Kruppel-like factor 5 (intestinal) -0.00619106
NKG7 natural killer cell granule protein 7 -0.00616902
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00616318
DNTT DNA nucleotidylexotransferase -0.0061523
PLPP3 phospholipid phosphatase 3 -0.00614559
DES desmin -0.00614321
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00614267
BIN1 bridging integrator 1 -0.00613339
TLR4 toll-like receptor 4 -0.00612473
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00610254
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.0060962
CALML3 calmodulin-like 3 -0.00608759
IL1B interleukin 1, beta -0.00607401
PITX3 paired-like homeodomain 3 -0.00607235
EPHA2 EPH receptor A2 -0.00601034
ADAM28 ADAM metallopeptidase domain 28 -0.0059954
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00598837
CLIP1 CAP-GLY domain containing linker protein 1 -0.00598816
TTN titin -0.00597926
LHFP lipoma HMGIC fusion partner -0.0059714
RHOF ras homolog family member F (in filopodia) -0.00596606
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00596031
TBX2 T-box 2 -0.00593867
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00592992
NXT2 nuclear transport factor 2-like export factor 2 -0.00592236
C3ORF52 chromosome 3 open reading frame 52 -0.00591667
SH3BGR SH3 domain binding glutamate-rich protein -0.00590075
EREG epiregulin -0.00589118
FABP7 fatty acid binding protein 7, brain -0.00589064
OPHN1 oligophrenin 1 -0.00588077
BMP6 bone morphogenetic protein 6 -0.00587405
THBS4 thrombospondin 4 -0.00587389
JUN jun proto-oncogene -0.00586111
NIP7 NIP7, nucleolar pre-rRNA processing protein -0.00585484
RIPK2 receptor-interacting serine-threonine kinase 2 -0.0058506
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00581861
CFH complement factor H -0.00581768
SPRR2B small proline-rich protein 2B -0.00581331
TH tyrosine hydroxylase -0.0057992
LTBP1 latent transforming growth factor beta binding protein 1 -0.00579491
AFF1 AF4/FMR2 family, member 1 -0.00578636