MLL1 complex Gene Set

Dataset GO Cellular Component Annotations 2023
Category structural or functional annotations
Type biological process
Description A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5. (Gene Ontology, GO_0071339)
External Link http://amigo.geneontology.org/amigo/term/GO:0071339
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Genes

31 proteins localized to the MLL1 complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol Name
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
C17ORF49 chromosome 17 open reading frame 49
CHD8 chromodomain helicase DNA binding protein 8
DPY30 dpy-30 homolog (C. elegans)
E2F6 E2F transcription factor 6
HCFC1 host cell factor C1
HCFC2 host cell factor C2
INO80C INO80 complex subunit C
KANSL1 KAT8 regulatory NSL complex subunit 1
KAT8 K(lysine) acetyltransferase 8
KMT2A lysine (K)-specific methyltransferase 2A
LAS1L LAS1-like (S. cerevisiae)
MAX MYC associated factor X
MCRS1 microspherule protein 1
MEN1 multiple endocrine neoplasia I
MGAM maltase-glucoamylase
PELP1 proline, glutamate and leucine rich protein 1
PHF20 PHD finger protein 20
PRPF31 pre-mRNA processing factor 31
RBBP5 retinoblastoma binding protein 5
RNF2 ring finger protein 2
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TEX10 testis expressed 10
WDR5 WD repeat domain 5