MLN8054 Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

25 kinases inhibited by the MLN8054 small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
AURKB aurora kinase B 1.34449
AURKA aurora kinase A 1.32726
BLK BLK proto-oncogene, Src family tyrosine kinase 1.3104
DDR1 discoidin domain receptor tyrosine kinase 1 1.26991
EPHA5 EPH receptor A5 1.24671
LCK LCK proto-oncogene, Src family tyrosine kinase 1.23916
STK17A serine/threonine kinase 17a 1.21703
TEC tec protein tyrosine kinase 1.20983
EPHB1 EPH receptor B1 1.19568
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.16838
MERTK MER proto-oncogene, tyrosine kinase 1.1424
TEK TEK tyrosine kinase, endothelial 1.1424
HCK HCK proto-oncogene, Src family tyrosine kinase 1.12988
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.11767
DDR2 discoidin domain receptor tyrosine kinase 2 1.10576
YES1 YES proto-oncogene 1, Src family tyrosine kinase 1.08845
AXL AXL receptor tyrosine kinase 1.06105
EPHA2 EPH receptor A2 1.03535
SIK1 salt-inducible kinase 1 0.997567
CLK2 CDC-like kinase 2 0.929345
FGR FGR proto-oncogene, Src family tyrosine kinase 0.922275
FGFR2 fibroblast growth factor receptor 2 0.918808
STK17B serine/threonine kinase 17b 0.889549
EPHA7 EPH receptor A7 0.883492
FGFR3 fibroblast growth factor receptor 3 0.877587