MMACHC Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria|The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 25974)
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Genes

387 genes differentially expressed following the MMACHC gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
CFHR4 complement factor H-related 4 3.42631
CCNB3 cyclin B3 3.42631
DUSP10 dual specificity phosphatase 10 3.42631
GJB5 gap junction protein, beta 5, 31.1kDa 3.42631
LRRC56 leucine rich repeat containing 56 3.42631
HBA1 hemoglobin, alpha 1 3.42631
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 3.42631
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 3.42631
COL8A1 collagen, type VIII, alpha 1 3.42631
BATF basic leucine zipper transcription factor, ATF-like 3.42631
ASB17 ankyrin repeat and SOCS box containing 17 3.42631
OLFM4 olfactomedin 4 3.42631
TOMM20L translocase of outer mitochondrial membrane 20 homolog (yeast)-like 3.42631
HES3 hes family bHLH transcription factor 3 3.42631
ADRB2 adrenoceptor beta 2, surface 3.42631
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 3.42631
EGFLAM EGF-like, fibronectin type III and laminin G domains 3.42631
NAPSA napsin A aspartic peptidase 3.42631
CEMP1 cementum protein 1 3.42631
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 3.42631
SCN2A sodium channel, voltage gated, type II alpha subunit 3.42631
IGFL3 IGF-like family member 3 3.42631
HEATR9 HEAT repeat containing 9 3.42631
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 3.42631
CABP4 calcium binding protein 4 3.42631
TMEM176B transmembrane protein 176B 3.42631
C19ORF38 chromosome 19 open reading frame 38 3.42631
RFPL3 ret finger protein-like 3 3.42631
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.42631
PRR29 proline rich 29 3.42631
LVRN laeverin 3.42631
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.42631
KIAA1755 KIAA1755 3.42631
SLC10A5 solute carrier family 10, member 5 3.42631
PMCH pro-melanin-concentrating hormone 3.42631
GRM6 glutamate receptor, metabotropic 6 3.42631
PITX3 paired-like homeodomain 3 3.42631
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 3.42631
MNX1 motor neuron and pancreas homeobox 1 3.42631
SPINT4 serine peptidase inhibitor, Kunitz type 4 3.42631
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.42631
KLLN killin, p53-regulated DNA replication inhibitor 3.42631
CPLX4 complexin 4 3.42631
GUCY2F guanylate cyclase 2F, retinal 3.42631
RGPD3 RANBP2-like and GRIP domain containing 3 3.42631
TTPA tocopherol (alpha) transfer protein 3.42631
FAM229A family with sequence similarity 229, member A 3.42631
DLX4 distal-less homeobox 4 3.42631
C8ORF74 chromosome 8 open reading frame 74 3.42631
KYNU kynureninase 3.42631
HIPK4 homeodomain interacting protein kinase 4 3.42631
NPIPA3 nuclear pore complex interacting protein family, member A3 3.42631
FAM216B family with sequence similarity 216, member B 3.42631
LGALS2 lectin, galactoside-binding, soluble, 2 3.42631
PASD1 PAS domain containing 1 3.42631
CIMAP2 ciliary microtubule associated protein 2 3.42631
DNAAF1 dynein, axonemal, assembly factor 1 3.42631
C9ORF43 chromosome 9 open reading frame 43 3.42631
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 3.42631
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.42631
IGSF22 immunoglobulin superfamily, member 22 3.42631
ASB9 ankyrin repeat and SOCS box containing 9 3.42631
ASB5 ankyrin repeat and SOCS box containing 5 3.42631
ASB4 ankyrin repeat and SOCS box containing 4 3.42631
TMEM190 transmembrane protein 190 3.42631
F5 coagulation factor V (proaccelerin, labile factor) 3.42631
HNF1A HNF1 homeobox A 3.42631
RHCG Rh family, C glycoprotein 3.42631
CXCL13 chemokine (C-X-C motif) ligand 13 3.42631
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 3.42631
KIF1C-AS1 KIF1C antisense RNA 1 3.42631
TAFA3 TAFA chemokine like family member 3 3.42631
JAML junction adhesion molecule like 3.42631
CFAP65 cilia and flagella associated protein 65 3.42631
PNMA8B PNMA family member 8B 3.42631
SQOR sulfide quinone oxidoreductase 3.42631
PHF24 PHD finger protein 24 3.42631
GOLGA6L7 golgin A6 family like 7 3.42631
ERVW-1 endogenous retrovirus group W, member 1 3.42631
PTH1R parathyroid hormone 1 receptor 3.42631
CLDN16 claudin 16 3.42631
LTB lymphotoxin beta (TNF superfamily, member 3) 3.42631
ASIC4 acid sensing (proton gated) ion channel family member 4 3.42631
LRRC73 leucine rich repeat containing 73 3.42631
CD48 CD48 molecule 3.42631
HPR haptoglobin-related protein 3.42631
CCR6 chemokine (C-C motif) receptor 6 3.42631
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 3.42631
AMBP alpha-1-microglobulin/bikunin precursor 3.42631
LTBP2 latent transforming growth factor beta binding protein 2 3.42631
TLE6 transducin-like enhancer of split 6 3.42631
LOC390937 Ets2 repressor factor-like 3.42631
LOC122394732 uncharacterized LOC122394732 3.42631
TAS2R31 taste receptor, type 2, member 31 3.42631
RAET1E retinoic acid early transcript 1E 3.42631
C3ORF80 chromosome 3 open reading frame 80 3.42631
GOLGA6L4 golgin A6 family-like 4 3.42631
CBLN2 cerebellin 2 precursor 3.42631
HAL histidine ammonia-lyase 3.42631
PGLYRP1 peptidoglycan recognition protein 1 3.42631
TACR2 tachykinin receptor 2 3.42631
SPDYC speedy/RINGO cell cycle regulator family member C 3.42631
RASAL3 RAS protein activator like 3 3.42631
ZAN zonadhesin (gene/pseudogene) 3.42631
MYH15 myosin, heavy chain 15 3.42631
TLR9 toll-like receptor 9 3.42631
ZNF575 zinc finger protein 575 3.42631
TACSTD2 tumor-associated calcium signal transducer 2 3.42631
GOLGA7B golgin A7 family, member B 3.42631
USH1G Usher syndrome 1G (autosomal recessive) 3.42631
PLA2G4D phospholipase A2, group IVD (cytosolic) 3.42631
AQP7 aquaporin 7 3.42631
HSPA1L heat shock 70kDa protein 1-like 3.42631
KLF1 Kruppel-like factor 1 (erythroid) 3.42631
ADAM8 ADAM metallopeptidase domain 8 3.42631
TMED6 transmembrane emp24 protein transport domain containing 6 3.42631
SNX31 sorting nexin 31 3.42631
EMP1 epithelial membrane protein 1 3.42631
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 3.42631
VWA3B von Willebrand factor A domain containing 3B 3.42631
AQP9 aquaporin 9 3.42631
C2CD4D C2 calcium-dependent domain containing 4D 3.42631
FATE1 fetal and adult testis expressed 1 3.42631
CLEC7A C-type lectin domain family 7, member A 3.42631
NPPA natriuretic peptide A 3.42631
CCDC154 coiled-coil domain containing 154 3.42631
CTF1 cardiotrophin 1 3.42631
CCL27 chemokine (C-C motif) ligand 27 3.42631
DNAJB13 DnaJ (Hsp40) homolog, subfamily B, member 13 3.42631
CST5 cystatin D 3.42631
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 3.42631
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.42631
PLA1A phospholipase A1 member A 3.42631
COL6A5 collagen, type VI, alpha 5 3.42631
MSMP microseminoprotein, prostate associated 3.42631
GPRC6A G protein-coupled receptor, class C, group 6, member A 3.42631
PPP1R27 protein phosphatase 1, regulatory subunit 27 3.42631
ACSS1 acyl-CoA synthetase short-chain family member 1 3.42631
STRC stereocilin 3.42631
VMO1 vitelline membrane outer layer 1 homolog (chicken) 3.42631
GOLGA8N golgin A8 family, member N 3.42631
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 3.42631
CFI complement factor I 3.42631
LOXHD1 lipoxygenase homology domains 1 3.42631
DND1 DND microRNA-mediated repression inhibitor 1 3.42631
TMEM31 transmembrane protein 31 3.42631
PCDHA13 protocadherin alpha 13 3.42631
RASD1 RAS, dexamethasone-induced 1 3.42631
ASTL astacin-like metallo-endopeptidase (M12 family) 3.42631
CFAP47 cilia and flagella associated protein 47 3.42631
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 3.42631
EPHA10 EPH receptor A10 3.42631
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 3.42631
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 3.42631
DLX1 distal-less homeobox 1 3.42631
KLK6 kallikrein-related peptidase 6 3.42631
TECRL trans-2,3-enoyl-CoA reductase-like 3.42631
PPP1R3G protein phosphatase 1, regulatory subunit 3G 3.42631
POU3F3 POU class 3 homeobox 3 3.42631
OR11G2 olfactory receptor, family 11, subfamily G, member 2 3.42631
AMDHD1 amidohydrolase domain containing 1 3.42631
TMEM45B transmembrane protein 45B 3.42631
SPNS3 spinster homolog 3 (Drosophila) 3.42631
FZD1 frizzled class receptor 1 3.42631
LST1 leukocyte specific transcript 1 3.42631
CLCNKA chloride channel, voltage-sensitive Ka 3.42631
IL17B interleukin 17B 3.42631
ROM1 retinal outer segment membrane protein 1 3.42631
PTGDR prostaglandin D2 receptor (DP) 3.42631
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 3.42631
FGF16 fibroblast growth factor 16 3.42631
FIGLA folliculogenesis specific basic helix-loop-helix 3.42631
CD177 CD177 molecule 3.42631
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 3.42631
TRIM29 tripartite motif containing 29 3.42631
ZNF396 zinc finger protein 396 3.42631
DUT deoxyuridine triphosphatase 3.42631
MROH8 maestro heat-like repeat family member 8 3.338
STKLD1 serine/threonine kinase-like domain containing 1 3.338
DRC10 dynein regulatory complex subunit 10 3.338
IL4I1 interleukin 4 induced 1 3.26518
GPR171 G protein-coupled receptor 171 3.14946
TADA3 transcriptional adaptor 3 3.10873
ELAVL3 ELAV like neuron-specific RNA binding protein 3 3.06754
CMTM1 CKLF-like MARVEL transmembrane domain containing 1 3.06754
LMTK3 lemur tyrosine kinase 3 2.95079
ASS1 argininosuccinate synthase 1 2.85428
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase 2.84859
TIMM29 translocase of inner mitochondrial membrane 29 2.83747
DGCR2 DiGeorge syndrome critical region gene 2 2.72521
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2.71142
PRIM2 primase, DNA, polypeptide 2 (58kDa) 2.69975
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 2.69618
FHL1 four and a half LIM domains 1 2.68544
BFSP1 beaded filament structural protein 1, filensin 2.67949
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 2.61939
ZCRB1 zinc finger CCHC-type and RNA binding motif 1 2.59678
PCNX3 pecanex 3 2.59035
SELENBP1 selenium binding protein 1 2.58816
AANAT aralkylamine N-acetyltransferase 2.58193
KIF12 kinesin family member 12 2.58193
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.58193
ADAM23 ADAM metallopeptidase domain 23 2.53347
NLGN2 neuroligin 2 2.51385
CERS3 ceramide synthase 3 2.50863
STARD5 StAR-related lipid transfer (START) domain containing 5 2.50863
TWF2 twinfilin actin binding protein 2 2.49727
ABITRAM actin binding transcription modulator 2.4937
SDS serine dehydratase 2.49304
ALX3 ALX homeobox 3 2.49304
CCDC91 coiled-coil domain containing 91 2.4887
RBM14 RNA binding motif protein 14 2.48866
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 2.47999
PTAR1 protein prenyltransferase alpha subunit repeat containing 1 2.46883
SMAD2 SMAD family member 2 2.41283
EXOC3L2 exocyst complex component 3-like 2 2.41184
CCDC74B coiled-coil domain containing 74B 2.41184
FNDC1 fibronectin type III domain containing 1 2.41184
ETNPPL ethanolamine-phosphate phospho-lyase 2.41184
VCX variable charge, X-linked 2.41184
MORF4L1 mortality factor 4 like 1 2.41032
DLG2 discs, large homolog 2 (Drosophila) 2.41032
PBX3 pre-B-cell leukemia homeobox 3 2.41032
TEAD3 TEA domain family member 3 2.37652
UCK1 uridine-cytidine kinase 1 2.37559
RPE ribulose-5-phosphate-3-epimerase 2.34515
PLSCR2 phospholipid scramblase 2 2.33607
TET1 tet methylcytosine dioxygenase 1 2.32831
MAP3K12 mitogen-activated protein kinase kinase kinase 12 2.32154
EGFL7 EGF-like-domain, multiple 7 2.29521
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2.26013
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.25938
UBR1 ubiquitin protein ligase E3 component n-recognin 1 2.2459
CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) 2.24422
MRPS14 mitochondrial ribosomal protein S14 2.22446
MOB4 MOB family member 4, phocein 2.21161
REPIN1 replication initiator 1 2.19094
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.18429
SLC38A4 solute carrier family 38, member 4 2.16722
PROK2 prokineticin 2 2.16722
TMEM33 transmembrane protein 33 2.15675
TPD52 tumor protein D52 2.13859
NSRP1 nuclear speckle splicing regulatory protein 1 2.13414
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.12589
SLC44A1 solute carrier family 44 (choline transporter), member 1 2.10333
DCAF8 DDB1 and CUL4 associated factor 8 2.10127
HACD3 3-hydroxyacyl-CoA dehydratase 3 2.09236
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.08256
KIF21B kinesin family member 21B 2.03712
FEM1C fem-1 homolog c (C. elegans) 2.03609
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 2.03438
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 2.02007
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) 2.01781
TDGF1 teratocarcinoma-derived growth factor 1 2.01684
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 2.01378
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 2.01378

decreased expression

Symbol Name Standardized Value
PVR poliovirus receptor -3.42631
RPL14 ribosomal protein L14 -3.42631
SHISA4 shisa family member 4 -3.42631
C1QTNF12 C1q and TNF related 12 -3.42631
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) -3.42631
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -3.42631
ACSL1 acyl-CoA synthetase long-chain family member 1 -3.42631
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 -3.42631
PCP4 Purkinje cell protein 4 -3.42631
ATP8B4 ATPase, class I, type 8B, member 4 -3.42631
C17ORF49 chromosome 17 open reading frame 49 -3.41449
FRZB frizzled-related protein -3.39864
NGFR nerve growth factor receptor -3.338
IFIH1 interferon induced with helicase C domain 1 -3.338
NBPF8 neuroblastoma breakpoint family, member 8 -3.338
CCDC159 coiled-coil domain containing 159 -3.338
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 -3.338
DGAT2 diacylglycerol O-acyltransferase 2 -3.338
OR2A12 olfactory receptor, family 2, subfamily A, member 12 -3.338
VAMP5 vesicle-associated membrane protein 5 -3.338
VSTM2L V-set and transmembrane domain containing 2 like -3.338
PCDHB9 protocadherin beta 9 -3.338
LRRC66 leucine rich repeat containing 66 -3.338
PRDM16 PR domain containing 16 -3.338
HRH4 histamine receptor H4 -3.338
PROZ protein Z, vitamin K-dependent plasma glycoprotein -3.338
FAM110D family with sequence similarity 110, member D -3.338
RNF39 ring finger protein 39 -3.338
CCDC17 coiled-coil domain containing 17 -3.338
IGFL4 IGF-like family member 4 -3.338
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -3.338
PCP4L1 Purkinje cell protein 4 like 1 -3.338
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 -3.338
F10 coagulation factor X -3.338
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C -3.338
UPK2 uroplakin 2 -3.338
IGIP IgA-inducing protein -3.338
MLIP muscular LMNA-interacting protein -3.338
SERINC4 serine incorporator 4 -3.338
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive) -3.338
GOLGA6C golgin A6 family, member C -3.338
TMEM61 transmembrane protein 61 -3.338
PCSK1 proprotein convertase subtilisin/kexin type 1 -3.338
ANO3 anoctamin 3 -3.338
DEFB131B defensin beta 131B -3.338
ERLN endoregulin -3.338
MUCL3 mucin like 3 -3.338
PLCL1 phospholipase C-like 1 -3.338
STAG3 stromal antigen 3 -3.32161
MAGEL2 melanoma antigen family L2 -3.14873
DESI1 desumoylating isopeptidase 1 -3.10873
VILL villin-like -3.03266
CNIH2 cornichon family AMPA receptor auxiliary protein 2 -2.95079
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.85428
DEDD2 death effector domain containing 2 -2.85428
LHX4 LIM homeobox 4 -2.80619
ZNF83 zinc finger protein 83 -2.80598
SPOPL speckle-type POZ protein-like -2.7157
GTF2B general transcription factor IIB -2.68544
ERVK3-1 endogenous retrovirus group K3, member 1 -2.68544
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -2.67353
XIRP2 xin actin binding repeat containing 2 -2.62938
PRICKLE3 prickle homolog 3 (Drosophila) -2.62938
SFN stratifin -2.62938
PTGR3 prostaglandin reductase 3 -2.62938
FAM50A family with sequence similarity 50, member A -2.62282
MT2A metallothionein 2A -2.58816
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -2.57343
AHDC1 AT hook, DNA binding motif, containing 1 -2.55328
CAPN3 calpain 3, (p94) -2.53347
MITF microphthalmia-associated transcription factor -2.53347
RNPS1 RNA binding protein S1, serine-rich domain -2.5264
ZRANB1 zinc finger, RAN-binding domain containing 1 -2.52108
DOCK8 dedicator of cytokinesis 8 -2.4937
PRNP prion protein -2.41179
RYR3 ryanodine receptor 3 -2.41115
ZC3H11A zinc finger CCCH-type containing 11A -2.39163
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -2.39163
SCGB2B2 secretoglobin, family 2B, member 2 -2.36926
FBXW9 F-box and WD repeat domain containing 9 -2.36029
RAB19 RAB19, member RAS oncogene family -2.36029
CBS cystathionine-beta-synthase -2.33297
SH3GL3 SH3-domain GRB2-like 3 -2.31303
SLC60A1 solute carrier family 60 member 1 -2.31059
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like -2.30274
ZNF778 zinc finger protein 778 -2.30094
LRRN1 leucine rich repeat neuronal 1 -2.27942
TMPRSS2 transmembrane protease, serine 2 -2.27804
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -2.27514
DOC2B double C2-like domains, beta -2.24594
ZSCAN22 zinc finger and SCAN domain containing 22 -2.24594
NQO2 NAD(P)H dehydrogenase, quinone 2 -2.24547
RUVBL1 RuvB-like AAA ATPase 1 -2.24547
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.23424
PTGR2 prostaglandin reductase 2 -2.22463
DISP3 dispatched RND transporter family member 3 -2.21161
ECH1 enoyl CoA hydratase 1, peroxisomal -2.20309
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -2.19454
ZNF502 zinc finger protein 502 -2.19094
ZNF623 zinc finger protein 623 -2.18587
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 -2.16518
LRRC20 leucine rich repeat containing 20 -2.16518
CXXC1 CXXC finger protein 1 -2.15507
NANOG Nanog homeobox -2.1406
EHBP1 EH domain binding protein 1 -2.13854
KCNK5 potassium channel, two pore domain subfamily K, member 5 -2.13776
DENND4C DENN/MADD domain containing 4C -2.13251
NGEF neuronal guanine nucleotide exchange factor -2.13232
POU3F4 POU class 3 homeobox 4 -2.13232
LRRC19 leucine rich repeat containing 19 -2.13232
CDH18 cadherin 18, type 2 -2.13232
LCAT lecithin-cholesterol acyltransferase -2.13232
PIGM phosphatidylinositol glycan anchor biosynthesis, class M -2.12952
TYRO3 TYRO3 protein tyrosine kinase -2.12952
SLU7 SLU7 splicing factor homolog (S. cerevisiae) -2.12177
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -2.09665
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) -2.0948
DNM2 dynamin 2 -2.08314
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.08314
ALOX12 arachidonate 12-lipoxygenase -2.0442
ACTR8 ARP8 actin-related protein 8 homolog (yeast) -2.04346
CISD3 CDGSH iron sulfur domain 3 -2.04346
ZNF506 zinc finger protein 506 -2.03583
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 -2.03331
TMEM144 transmembrane protein 144 -2.02007
RUMY2 RUMY family member 2 -2.02007
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -2.01378
ZNF625 zinc finger protein 625 -2.01378
ZNF619 zinc finger protein 619 -2.01378
PLAAT3 phospholipase A and acyltransferase 3 -2.01108
CABLES1 Cdk5 and Abl enzyme substrate 1 -2.00209