| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria|The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq, Oct 2009] (NCBI Entrez Gene Database, 25974) |
| External Link | https://ncbi.nlm.nih.gov/gene/25974 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the MMACHC gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | 0.0248856 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.0184055 |
| MAGEA3 | melanoma antigen family A3 | 0.0160533 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0153763 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0149183 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0137741 |
| TPBG | trophoblast glycoprotein | 0.0128151 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.012546 |
| PLK2 | polo-like kinase 2 | 0.0123565 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0122003 |
| MX1 | MX dynamin-like GTPase 1 | 0.0113504 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.011287 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.0109168 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0108781 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0108216 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0106277 |
| MAGEA12 | melanoma antigen family A12 | 0.0104594 |
| IER5 | immediate early response 5 | 0.0104472 |
| IL32 | interleukin 32 | 0.0100569 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0099844 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00991794 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00981642 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00977005 |
| PCDH9 | protocadherin 9 | 0.00964065 |
| IFI44 | interferon-induced protein 44 | 0.00963685 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00962324 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00959998 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00959058 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00954827 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00935506 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00933216 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00930658 |
| CCNA2 | cyclin A2 | 0.0092975 |
| S100A11 | S100 calcium binding protein A11 | 0.00920786 |
| IRF7 | interferon regulatory factor 7 | 0.00904864 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00904312 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00890194 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.0087944 |
| ABHD6 | abhydrolase domain containing 6 | 0.0087738 |
| TRIP6 | thyroid hormone receptor interactor 6 | 0.00874589 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00867742 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.00865824 |
| GOLM1 | golgi membrane protein 1 | 0.00862297 |
| UPP1 | uridine phosphorylase 1 | 0.0085294 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0085235 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00845678 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0084257 |
| TRIM16 | tripartite motif containing 16 | 0.00837664 |
| GNAS | GNAS complex locus | 0.00835092 |
| IFI35 | interferon-induced protein 35 | 0.00835033 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00833905 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00831943 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.00829888 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00824354 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00821222 |
| XAF1 | XIAP associated factor 1 | 0.0081856 |
| IFI44L | interferon-induced protein 44-like | 0.00818221 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00816545 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00807422 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00806933 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00806456 |
| KRT15 | keratin 15, type I | 0.00805834 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00804267 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00801305 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.00787695 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00781706 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00780894 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00777749 |
| PLXNC1 | plexin C1 | 0.00775134 |
| SP110 | SP110 nuclear body protein | 0.00769776 |
| IRF9 | interferon regulatory factor 9 | 0.00768568 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | 0.00765129 |
| CD163 | CD163 molecule | 0.00757643 |
| CD81 | CD81 molecule | 0.00755887 |
| VWF | von Willebrand factor | 0.00755766 |
| EGR2 | early growth response 2 | 0.00752717 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00751544 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00751416 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00750223 |
| MAGED2 | melanoma antigen family D2 | 0.00747766 |
| MT1X | metallothionein 1X | 0.00747283 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00746219 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00742731 |
| STK10 | serine/threonine kinase 10 | 0.00740873 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00740751 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00739925 |
| IL6ST | interleukin 6 signal transducer | 0.00738648 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00738005 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00737942 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00729519 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00729398 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00726444 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00725917 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00723979 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.0072326 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00721365 |
| MX2 | MX dynamin-like GTPase 2 | 0.00719107 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00715535 |
| KRT7 | keratin 7, type II | 0.00714824 |
| ZNF91 | zinc finger protein 91 | 0.00713868 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00710138 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.00710116 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00706697 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00706433 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00705123 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.00704302 |
| KRT17 | keratin 17, type I | 0.00702737 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00700628 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.00696055 |
| EFHD2 | EF-hand domain family, member D2 | 0.00694448 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00691037 |
| DCHS1 | dachsous cadherin-related 1 | 0.00689696 |
| CTSL | cathepsin L | 0.00689214 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00686573 |
| PRAME | preferentially expressed antigen in melanoma | 0.00684657 |
| TSPAN8 | tetraspanin 8 | 0.0068421 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00684073 |
| KRT14 | keratin 14, type I | 0.00683032 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.00682775 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00679559 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00677696 |
| PXDN | peroxidasin | 0.00676784 |
| DUSP5 | dual specificity phosphatase 5 | 0.00673921 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 0.00673674 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00670817 |
| HMOX1 | heme oxygenase 1 | 0.006706 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00670463 |
| FN1 | fibronectin 1 | 0.00669813 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00669297 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00664177 |
| PDLIM4 | PDZ and LIM domain 4 | 0.00661602 |
| VNN1 | vanin 1 | 0.00659226 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | 0.00659128 |
| PPIF | peptidylprolyl isomerase F | 0.0065724 |
| USP6NL | USP6 N-terminal like | 0.00657239 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00654596 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00653771 |
| EPHA2 | EPH receptor A2 | 0.00649439 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00647789 |
| G0S2 | G0/G1 switch 2 | 0.00647565 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00647389 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00645154 |
| FZD2 | frizzled class receptor 2 | 0.00644756 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.0064328 |
| NUTF2 | nuclear transport factor 2 | 0.00642697 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | 0.00641625 |
| RUNX3 | runt-related transcription factor 3 | 0.00640244 |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 0.00640226 |
| MYBPC1 | myosin binding protein C, slow type | 0.00637091 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00636886 |
| OLFML2A | olfactomedin-like 2A | 0.00636405 |
| WASHC4 | WASH complex subunit 4 | 0.00636098 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00635736 |
| ADRB2 | adrenoceptor beta 2, surface | 0.00633413 |
| DBN1 | drebrin 1 | 0.0063158 |
| SCAND1 | SCAN domain containing 1 | 0.00629768 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00627388 |
| FOXO1 | forkhead box O1 | 0.00626751 |
| PWWP3A | PWWP domain containing 3A, DNA repair factor | 0.00625034 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0062412 |
| KLF6 | Kruppel-like factor 6 | 0.00624062 |
| NINJ1 | ninjurin 1 | 0.00621195 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00620991 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00620553 |
| ZFHX4 | zinc finger homeobox 4 | 0.00620327 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00620327 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.0061869 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | 0.00618466 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.00617448 |
| IL1RN | interleukin 1 receptor antagonist | 0.00617 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00616874 |
| KRT13 | keratin 13, type I | 0.00616602 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.00615337 |
| C1QA | complement component 1, q subcomponent, A chain | 0.00611849 |
| RB1 | retinoblastoma 1 | 0.00611806 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00610473 |
| RBPMS | RNA binding protein with multiple splicing | 0.00610464 |
| KIAA0100 | KIAA0100 | 0.00610343 |
| MMP7 | matrix metallopeptidase 7 | 0.0060938 |
| TRIM29 | tripartite motif containing 29 | 0.00609098 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00608869 |
| STAB1 | stabilin 1 | 0.00605923 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00605749 |
| FBN2 | fibrillin 2 | 0.0060556 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00603767 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00603239 |
| TGFA | transforming growth factor, alpha | 0.00600404 |
| BEX4 | brain expressed, X-linked 4 | 0.00599324 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00599208 |
| GOLGA8A | golgin A8 family, member A | 0.0059765 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00597101 |
| CNTN1 | contactin 1 | 0.00596333 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00594927 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.00594479 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00593651 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00591464 |
| CPNE1 | copine I | 0.00591448 |
| MYLK | myosin light chain kinase | 0.00590659 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00589229 |
| CFB | complement factor B | 0.00588965 |
| POU2AF1 | POU class 2 associating factor 1 | 0.0058852 |
| H1-0 | H1.0 linker histone | 0.00587818 |
| DUSP7 | dual specificity phosphatase 7 | 0.00587626 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | 0.00586328 |
| LOXL2 | lysyl oxidase-like 2 | 0.0058567 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00584858 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00583928 |
| OXTR | oxytocin receptor | 0.00580954 |
| BGN | biglycan | 0.00579215 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00574628 |
| EMP1 | epithelial membrane protein 1 | 0.00573267 |
| PDZD2 | PDZ domain containing 2 | 0.00572965 |
| KYNU | kynureninase | 0.00572444 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00572148 |
| TYMP | thymidine phosphorylase | 0.00571204 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00569357 |
| TESC | tescalcin | 0.00568713 |
| NOP56 | NOP56 ribonucleoprotein | 0.00567436 |
| TFF1 | trefoil factor 1 | 0.00566746 |
| TSPYL5 | TSPY-like 5 | 0.0056613 |
| CD14 | CD14 molecule | 0.00565881 |
| CTSK | cathepsin K | 0.00565573 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.00565278 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00565039 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00564495 |
| LY96 | lymphocyte antigen 96 | 0.00564311 |
| ANXA3 | annexin A3 | 0.00564067 |
| MT1F | metallothionein 1F | 0.0056351 |
| SQSTM1 | sequestosome 1 | 0.00562783 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00560102 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00559785 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.00559063 |
| WDR43 | WD repeat domain 43 | 0.00557743 |
| SYNM | synemin, intermediate filament protein | 0.00556834 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00555617 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00555136 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit | 0.00554898 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00554419 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.00554373 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00554225 |
| GDF15 | growth differentiation factor 15 | 0.00553852 |
| KLK10 | kallikrein-related peptidase 10 | 0.00553832 |
| EIF6 | eukaryotic translation initiation factor 6 | 0.00553761 |
| WDR45 | WD repeat domain 45 | 0.00553183 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | 0.00549355 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00547962 |
| RND3 | Rho family GTPase 3 | 0.00547882 |
| C1S | complement component 1, s subcomponent | 0.00547415 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00547158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0280356 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0186766 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0164142 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.0132154 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.0116075 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.01157 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.0104415 |
| MAP7 | microtubule-associated protein 7 | -0.0102818 |
| CYB5A | cytochrome b5 type A (microsomal) | -0.0100174 |
| TXNDC9 | thioredoxin domain containing 9 | -0.00987512 |
| ADI1 | acireductone dioxygenase 1 | -0.0098688 |
| CLC | Charcot-Leyden crystal galectin | -0.00986023 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00939051 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00938909 |
| TOX3 | TOX high mobility group box family member 3 | -0.00913928 |
| ELANE | elastase, neutrophil expressed | -0.00911099 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00899968 |
| NVL | nuclear VCP-like | -0.00886119 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00879644 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00867147 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0086382 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00854762 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00846265 |
| EMX2 | empty spiracles homeobox 2 | -0.0084156 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00833926 |
| CST7 | cystatin F (leukocystatin) | -0.00831214 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00827899 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00825649 |
| S100A8 | S100 calcium binding protein A8 | -0.0082185 |
| FAM3C | family with sequence similarity 3, member C | -0.00805626 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00802011 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00801164 |
| PRTN3 | proteinase 3 | -0.00792059 |
| AZU1 | azurocidin 1 | -0.0078396 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00780548 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00772568 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0076835 |
| ASF1A | anti-silencing function 1A histone chaperone | -0.00768217 |
| HMGB3 | high mobility group box 3 | -0.00767381 |
| SMYD3 | SET and MYND domain containing 3 | -0.00755614 |
| RNASE3 | ribonuclease, RNase A family, 3 | -0.00753483 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | -0.00750698 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.00750049 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0074857 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0074673 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0074524 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00743958 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.00731275 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00729783 |
| DCK | deoxycytidine kinase | -0.0072766 |
| CD69 | CD69 molecule | -0.00727426 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00726966 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00725716 |
| TMEM168 | transmembrane protein 168 | -0.00716811 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00715735 |
| EREG | epiregulin | -0.00710617 |
| RGCC | regulator of cell cycle | -0.00701276 |
| NPR3 | natriuretic peptide receptor 3 | -0.0070079 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00698717 |
| HBD | hemoglobin, delta | -0.0069378 |
| BIN2 | bridging integrator 2 | -0.00689028 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00685523 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00683935 |
| TBX2 | T-box 2 | -0.00681735 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -0.00681701 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00680508 |
| MEIS1 | Meis homeobox 1 | -0.00678278 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | -0.0067772 |
| MRTFB | myocardin related transcription factor B | -0.00677543 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.00677112 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -0.00672547 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00671375 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0066809 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00665932 |
| DIPK1A | divergent protein kinase domain 1A | -0.00664216 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00660359 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00659884 |
| APOC2 | apolipoprotein C-II | -0.00659425 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00657143 |
| DUSP2 | dual specificity phosphatase 2 | -0.00656066 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00656 |
| ACKR3 | atypical chemokine receptor 3 | -0.0065492 |
| CRYM | crystallin, mu | -0.00653488 |
| CBR4 | carbonyl reductase 4 | -0.00651007 |
| EFHD1 | EF-hand domain family, member D1 | -0.00650952 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00650931 |
| PANK3 | pantothenate kinase 3 | -0.00650231 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00643488 |
| FAM149A | family with sequence similarity 149, member A | -0.0064162 |
| CYCS | cytochrome c, somatic | -0.00635596 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | -0.00635105 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.0063484 |
| ITGA8 | integrin, alpha 8 | -0.00633652 |
| HPGDS | hematopoietic prostaglandin D synthase | -0.00630874 |
| RAB4A | RAB4A, member RAS oncogene family | -0.00629859 |
| ADA | adenosine deaminase | -0.0062748 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00626685 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00625286 |
| ANGPT1 | angiopoietin 1 | -0.00625155 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.00624838 |
| SFTPA2 | surfactant protein A2 | -0.00624739 |
| GPR183 | G protein-coupled receptor 183 | -0.00623132 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0062165 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00620956 |
| ZNF451 | zinc finger protein 451 | -0.00620125 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00619765 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 | -0.00619201 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00619094 |
| NTS | neurotensin | -0.00618609 |
| DSTN | destrin (actin depolymerizing factor) | -0.00618059 |
| GLO1 | glyoxalase I | -0.00617885 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00615841 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00615239 |
| PLPP3 | phospholipid phosphatase 3 | -0.0061281 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00611939 |
| MFAP5 | microfibrillar associated protein 5 | -0.00610134 |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 | -0.00605213 |
| RHOA | ras homolog family member A | -0.00601237 |
| CETN2 | centrin, EF-hand protein, 2 | -0.0060017 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0059768 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | -0.00597502 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00596287 |
| ZNF331 | zinc finger protein 331 | -0.00596162 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.0059589 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00592824 |
| BEX1 | brain expressed, X-linked 1 | -0.00592366 |
| RAB20 | RAB20, member RAS oncogene family | -0.00588351 |
| UXS1 | UDP-glucuronate decarboxylase 1 | -0.0058714 |
| C14ORF132 | chromosome 14 open reading frame 132 | -0.00586932 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | -0.00585292 |
| PIR | pirin (iron-binding nuclear protein) | -0.0058406 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00582362 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.005821 |
| CCNB2 | cyclin B2 | -0.00580972 |
| FOXC1 | forkhead box C1 | -0.00578424 |
| CD2 | CD2 molecule | -0.00578098 |
| STOM | stomatin | -0.00577244 |
| TMEM14B | transmembrane protein 14B | -0.00576818 |
| CALU | calumenin | -0.00575942 |
| CHGA | chromogranin A | -0.00573663 |
| FCGBP | Fc fragment of IgG binding protein | -0.00569559 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | -0.00569273 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00568521 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.00567956 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | -0.00567001 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00566818 |
| MGST3 | microsomal glutathione S-transferase 3 | -0.0056671 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.005664 |
| INSIG1 | insulin induced gene 1 | -0.0056386 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.00562992 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00562763 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00560368 |
| HBB | hemoglobin, beta | -0.00558377 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00556811 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00555316 |
| TXNIP | thioredoxin interacting protein | -0.0055161 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.00551015 |
| STMN2 | stathmin 2 | -0.00549498 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00549456 |
| RPA3 | replication protein A3, 14kDa | -0.00547253 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00545997 |
| AHI1 | Abelson helper integration site 1 | -0.00545823 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00544314 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00541567 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00540314 |
| ZG16 | zymogen granule protein 16 | -0.00539461 |
| NREP | neuronal regeneration related protein | -0.00538111 |
| MPO | myeloperoxidase | -0.00537434 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00536374 |
| DAZAP2 | DAZ associated protein 2 | -0.00536277 |
| COLEC12 | collectin sub-family member 12 | -0.00534605 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.0053457 |
| COG7 | component of oligomeric golgi complex 7 | -0.00533049 |
| DDHD2 | DDHD domain containing 2 | -0.00530305 |
| SCP2 | sterol carrier protein 2 | -0.00530182 |
| S100A6 | S100 calcium binding protein A6 | -0.00529848 |
| TLCD3A | TLC domain containing 3A | -0.00529724 |
| FAM8A1 | family with sequence similarity 8, member A1 | -0.00529438 |
| CDHR1 | cadherin-related family member 1 | -0.00527396 |
| CHGB | chromogranin B | -0.00527369 |
| SELENBP1 | selenium binding protein 1 | -0.00526541 |
| SEH1L | SEH1-like (S. cerevisiae) | -0.0052623 |
| EAF2 | ELL associated factor 2 | -0.00525812 |
| DENND2D | DENN/MADD domain containing 2D | -0.00524214 |
| AQP1 | aquaporin 1 (Colton blood group) | -0.00523927 |
| RHOT1 | ras homolog family member T1 | -0.00523577 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | -0.00523081 |
| FABP1 | fatty acid binding protein 1, liver | -0.0052306 |
| ATP8B4 | ATPase, class I, type 8B, member 4 | -0.00522862 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | -0.00522508 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00522144 |
| MRS2 | MRS2 magnesium transporter | -0.00521036 |
| STX6 | syntaxin 6 | -0.00520393 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | -0.00520236 |
| SRP72 | signal recognition particle 72kDa | -0.00519714 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | -0.00519556 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00517442 |
| MEF2C | myocyte enhancer factor 2C | -0.00515926 |
| BDKRB1 | bradykinin receptor B1 | -0.00515356 |
| LOR | loricrin | -0.00514251 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.0051189 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00511778 |
| RRM2 | ribonucleotide reductase M2 | -0.00510975 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | -0.00509483 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00508726 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00508344 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00507599 |
| HLTF | helicase-like transcription factor | -0.00506718 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.00506294 |
| NINJ2 | ninjurin 2 | -0.00505887 |
| GSAP | gamma-secretase activating protein | -0.00505664 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -0.00505485 |
| GPER1 | G protein-coupled estrogen receptor 1 | -0.00504829 |
| ADK | adenosine kinase | -0.00504467 |
| NSF | N-ethylmaleimide-sensitive factor | -0.00503415 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00501319 |
| HSP90B2P | heat shock protein 90kDa beta (Grp94), member 2, pseudogene | -0.00501003 |
| EPHA1 | EPH receptor A1 | -0.00500819 |
| SESN1 | sestrin 1 | -0.0050063 |
| TMEM47 | transmembrane protein 47 | -0.00500307 |
| DPP4 | dipeptidyl-peptidase 4 | -0.00499815 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00498784 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00497946 |
| CD200 | CD200 molecule | -0.00497428 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) | -0.00496607 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00496435 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00494693 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00494344 |
| TMEM38B | transmembrane protein 38B | -0.00493953 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | -0.00493913 |
| ABHD17B | abhydrolase domain containing 17B | -0.00493867 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.00493107 |
| CA4 | carbonic anhydrase IV | -0.00491858 |
| GAL | galanin/GMAP prepropeptide | -0.00490341 |
| CADM1 | cell adhesion molecule 1 | -0.00489225 |
| CHEK1 | checkpoint kinase 1 | -0.00486991 |
| RAB33A | RAB33A, member RAS oncogene family | -0.00485381 |
| EAPP | E2F-associated phosphoprotein | -0.0048475 |
| COMMD8 | COMM domain containing 8 | -0.00483776 |
| ITGB7 | integrin, beta 7 | -0.00482902 |
| SMIM8 | small integral membrane protein 8 | -0.00482671 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 | -0.00482143 |
| METTL8 | methyltransferase like 8 | -0.00480282 |
| TMEM50B | transmembrane protein 50B | -0.00480069 |
| CLCA1 | chloride channel accessory 1 | -0.0047961 |
| ATP11B | ATPase, class VI, type 11B | -0.00477392 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.00477272 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00476069 |
