MMP1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description matrix metallopeptidase 1|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 4312)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_MMP1
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Genes

32 co-expressed genes for MMP1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CALU calumenin
CCL2 chemokine (C-C motif) ligand 2
CCL7 chemokine (C-C motif) ligand 7
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEMIP cell migration inducing protein, hyaluronan binding
CSF3 colony stimulating factor 3 (granulocyte)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
FBN1 fibrillin 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GREM1 gremlin 1, DAN family BMP antagonist
IL1B interleukin 1, beta
IL6 interleukin 6
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LOXL1 lysyl oxidase-like 1
LOXL2 lysyl oxidase-like 2
LRRC17 leucine rich repeat containing 17
MMP1 matrix metallopeptidase 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
PXDN peroxidasin
RAI14 retinoic acid induced 14
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
THBS2 thrombospondin 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TWSG1 twisted gastrulation BMP signaling modulator 1