| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | matrix metallopeptidase 13|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4322) |
| External Link | https://ncbi.nlm.nih.gov/gene/4322 |
| Similar Terms | |
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499 genes differentially expressed following the MMP13 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPB1 | heat shock 27kDa protein 1 | 0.00845093 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0079559 |
| G0S2 | G0/G1 switch 2 | 0.00722419 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00718286 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00695793 |
| PLN | phospholamban | 0.00680046 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00643659 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00627495 |
| FILIP1L | filamin A interacting protein 1-like | 0.00615081 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00614734 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00614024 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00605599 |
| FHL1 | four and a half LIM domains 1 | 0.00601179 |
| TOX3 | TOX high mobility group box family member 3 | 0.00585393 |
| CCN2 | cellular communication network factor 2 | 0.00582648 |
| TSPYL5 | TSPY-like 5 | 0.00579085 |
| H1-0 | H1.0 linker histone | 0.00564144 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00556922 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0055583 |
| IL1RN | interleukin 1 receptor antagonist | 0.00554411 |
| FST | follistatin | 0.00547908 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00547081 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.00546127 |
| MAOA | monoamine oxidase A | 0.00543119 |
| NPEPL1 | aminopeptidase-like 1 | 0.00541926 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00541118 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00538633 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00533105 |
| LYST | lysosomal trafficking regulator | 0.00532578 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00532559 |
| ENAH | enabled homolog (Drosophila) | 0.00532551 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00530205 |
| FBLN1 | fibulin 1 | 0.00529176 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.0052876 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00520811 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00519863 |
| C7 | complement component 7 | 0.00519507 |
| RPL10 | ribosomal protein L10 | 0.00513425 |
| EGR1 | early growth response 1 | 0.00509399 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00503008 |
| PFKL | phosphofructokinase, liver | 0.0050188 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00496982 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00496466 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.00487952 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00483089 |
| GOLGA8A | golgin A8 family, member A | 0.00482955 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0048247 |
| MPDZ | multiple PDZ domain protein | 0.00478058 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00476648 |
| PLIN1 | perilipin 1 | 0.00474557 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00472956 |
| PLEK | pleckstrin | 0.00471954 |
| GATA2 | GATA binding protein 2 | 0.00471462 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00470436 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00467018 |
| CTSH | cathepsin H | 0.00466245 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00465048 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00464545 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.00462808 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00456727 |
| CFD | complement factor D (adipsin) | 0.00456598 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00455357 |
| RNF167 | ring finger protein 167 | 0.00449809 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00448417 |
| CPE | carboxypeptidase E | 0.00442131 |
| PNN | pinin, desmosome associated protein | 0.00440557 |
| AEBP1 | AE binding protein 1 | 0.00434979 |
| IL1B | interleukin 1, beta | 0.00432905 |
| ASPN | asporin | 0.00432508 |
| TJP2 | tight junction protein 2 | 0.00432026 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00429063 |
| MX1 | MX dynamin-like GTPase 1 | 0.00428007 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | 0.0042691 |
| DES | desmin | 0.00426752 |
| NIBAN1 | niban apoptosis regulator 1 | 0.00426351 |
| BMP2 | bone morphogenetic protein 2 | 0.004254 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | 0.00425336 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00425227 |
| BAG3 | BCL2-associated athanogene 3 | 0.00423256 |
| RORA | RAR-related orphan receptor A | 0.00421423 |
| NID1 | nidogen 1 | 0.00418891 |
| CUX1 | cut-like homeobox 1 | 0.00418232 |
| STK26 | serine/threonine protein kinase 26 | 0.00418205 |
| LYZ | lysozyme | 0.00417591 |
| FUT9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) | 0.00416811 |
| DIPK1A | divergent protein kinase domain 1A | 0.00416526 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00414645 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00413392 |
| TARDBP | TAR DNA binding protein | 0.00413381 |
| TBX3 | T-box 3 | 0.00412803 |
| MFAP4 | microfibrillar-associated protein 4 | 0.00412109 |
| VCAN | versican | 0.00411683 |
| DST | dystonin | 0.00411415 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00409003 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 | 0.00408616 |
| PSCA | prostate stem cell antigen | 0.00407797 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00407669 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00406072 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00405114 |
| PLTP | phospholipid transfer protein | 0.0040459 |
| PLS3 | plastin 3 | 0.00404395 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00404235 |
| DPT | dermatopontin | 0.00402386 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.0040191 |
| SQLE | squalene epoxidase | 0.00401597 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00400992 |
| MCM2 | minichromosome maintenance complex component 2 | 0.00399405 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00397659 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00396729 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00395714 |
| PIH1D1 | PIH1 domain containing 1 | 0.00395021 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | 0.00393353 |
| MYO6 | myosin VI | 0.00392489 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.00392286 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00390346 |
| NAV2 | neuron navigator 2 | 0.00385834 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00385783 |
| GSDME | gasdermin E | 0.00385468 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00385129 |
| ESRP2 | epithelial splicing regulatory protein 2 | 0.00384481 |
| FAM193B | family with sequence similarity 193, member B | 0.00384356 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00381841 |
| BTG2 | BTG family, member 2 | 0.00380206 |
| GRN | granulin | 0.00379604 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0037818 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.00376797 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00374836 |
| DVL3 | dishevelled segment polarity protein 3 | 0.00371935 |
| DSE | dermatan sulfate epimerase | 0.00371303 |
| PLXNC1 | plexin C1 | 0.00371244 |
| INA | internexin neuronal intermediate filament protein, alpha | 0.00370869 |
| CD27 | CD27 molecule | 0.00370699 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00370603 |
| CHFR | checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase | 0.00370521 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00369548 |
| PPL | periplakin | 0.00366839 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.00366597 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.00365964 |
| GNAS | GNAS complex locus | 0.00365913 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00365458 |
| HMG20B | high mobility group 20B | 0.00364669 |
| IFI44L | interferon-induced protein 44-like | 0.00364515 |
| NINL | ninein-like | 0.00363518 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.00363124 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.00362842 |
| VWF | von Willebrand factor | 0.00362632 |
| NAV3 | neuron navigator 3 | 0.00362232 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00361921 |
| AOC3 | amine oxidase, copper containing 3 | 0.00361849 |
| AGR2 | anterior gradient 2 | 0.00361583 |
| LOXL1 | lysyl oxidase-like 1 | 0.00361136 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00360926 |
| STK10 | serine/threonine kinase 10 | 0.00359382 |
| GKN1 | gastrokine 1 | 0.00357809 |
| XIC | X chromosome inactivation center | 0.00357328 |
| CNTN1 | contactin 1 | 0.00355217 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.00355191 |
| RBM26 | RNA binding motif protein 26 | 0.0035467 |
| NID2 | nidogen 2 (osteonidogen) | 0.00354509 |
| ITGA8 | integrin, alpha 8 | 0.0035326 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00353064 |
| ISL1 | ISL LIM homeobox 1 | 0.00352417 |
| INTS3 | integrator complex subunit 3 | 0.00352166 |
| GATA6 | GATA binding protein 6 | 0.00352024 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00351307 |
| ACTN1 | actinin, alpha 1 | 0.00350537 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00349492 |
| CTSA | cathepsin A | 0.00348135 |
| ADRB2 | adrenoceptor beta 2, surface | 0.00347649 |
| MMP9 | matrix metallopeptidase 9 | 0.00347218 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00346943 |
| PEG10 | paternally expressed 10 | 0.00346693 |
| FOXF2 | forkhead box F2 | 0.00343692 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00343059 |
| YTHDC1 | YTH domain containing 1 | 0.00342252 |
| NPY | neuropeptide Y | 0.00341374 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00339645 |
| PXDC1 | PX domain containing 1 | 0.00339354 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00339114 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00338551 |
| SOX15 | SRY (sex determining region Y)-box 15 | 0.0033832 |
| MAPK10 | mitogen-activated protein kinase 10 | 0.003365 |
| PMM2 | phosphomannomutase 2 | 0.00334275 |
| WBP5 | WW domain binding protein 5 | 0.00334215 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00334149 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00334022 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00333825 |
| NBEA | neurobeachin | 0.0033371 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00333508 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00333378 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.003328 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00332764 |
| SPEN | spen family transcriptional repressor | 0.00332763 |
| HTRA1 | HtrA serine peptidase 1 | 0.0033251 |
| CCND2 | cyclin D2 | 0.00331757 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00331577 |
| MORF4L2 | mortality factor 4 like 2 | 0.00330877 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0033058 |
| USP48 | ubiquitin specific peptidase 48 | 0.00329691 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.00329093 |
| DGKA | diacylglycerol kinase, alpha 80kDa | 0.00328431 |
| MEIS2 | Meis homeobox 2 | 0.00328375 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00328248 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00327791 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 0.00326744 |
| NXN | nucleoredoxin | 0.0032667 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 0.00326117 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00325989 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 | 0.00325634 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.00325003 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00323769 |
| STAB1 | stabilin 1 | 0.00322906 |
| PRPF8 | pre-mRNA processing factor 8 | 0.00320941 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00320776 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00320291 |
| PER3 | period circadian clock 3 | 0.0032014 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.00319975 |
| RGS5 | regulator of G-protein signaling 5 | 0.00318528 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00317431 |
| DSG2 | desmoglein 2 | 0.0031661 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00316416 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00314943 |
| PAPOLA | poly(A) polymerase alpha | 0.00314858 |
| HIP1R | huntingtin interacting protein 1 related | 0.00313864 |
| CCNL2 | cyclin L2 | 0.0031376 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | 0.00313252 |
| BLNK | B-cell linker | 0.00311634 |
| THOC2 | THO complex 2 | 0.00311483 |
| MITF | microphthalmia-associated transcription factor | 0.00311099 |
| CXXC1 | CXXC finger protein 1 | 0.00311066 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.00311013 |
| PXDN | peroxidasin | 0.00310898 |
| REC8 | REC8 meiotic recombination protein | 0.00310527 |
| PLAU | plasminogen activator, urokinase | 0.00309687 |
| CALD1 | caldesmon 1 | 0.00309634 |
| CHMP4A | charged multivesicular body protein 4A | 0.00308543 |
| COL6A3 | collagen, type VI, alpha 3 | 0.00308363 |
| CLUH | clustered mitochondria (cluA/CLU1) homolog | 0.00308252 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.00308094 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.00307545 |
| TCP1 | t-complex 1 | 0.00306915 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00306774 |
| COL10A1 | collagen, type X, alpha 1 | 0.00306236 |
| FAM13A | family with sequence similarity 13, member A | 0.00305709 |
| CCNB1 | cyclin B1 | 0.00305247 |
| USO1 | USO1 vesicle transport factor | 0.0030503 |
| PERP | PERP, TP53 apoptosis effector | 0.0030499 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00303829 |
| DUSP6 | dual specificity phosphatase 6 | 0.00302881 |
| USP3 | ubiquitin specific peptidase 3 | 0.00302749 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MMP1 | matrix metallopeptidase 1 | -0.0147659 |
| FABP7 | fatty acid binding protein 7, brain | -0.00881849 |
| PROM1 | prominin 1 | -0.00810253 |
| MMP3 | matrix metallopeptidase 3 | -0.00799347 |
| PODXL | podocalyxin-like | -0.00774459 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00759637 |
| FCGBP | Fc fragment of IgG binding protein | -0.0075066 |
| TCTA | T-cell leukemia translocation altered | -0.00722367 |
| FOLR1 | folate receptor 1 (adult) | -0.00708117 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00702418 |
| NNMT | nicotinamide N-methyltransferase | -0.00691282 |
| COL9A3 | collagen, type IX, alpha 3 | -0.0067932 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00655584 |
| NPR3 | natriuretic peptide receptor 3 | -0.00653819 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00648689 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00647126 |
| PDZK1 | PDZ domain containing 1 | -0.0064694 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00645812 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.0062607 |
| MAP7 | microtubule-associated protein 7 | -0.00621427 |
| PRKD3 | protein kinase D3 | -0.0062064 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | -0.00605791 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0058509 |
| AREG | amphiregulin | -0.00572211 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00553431 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00540488 |
| RPA3 | replication protein A3, 14kDa | -0.00534085 |
| POSTN | periostin, osteoblast specific factor | -0.00532529 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00522343 |
| OLFM4 | olfactomedin 4 | -0.0052217 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00515259 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.00513032 |
| REEP5 | receptor accessory protein 5 | -0.00509576 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.00506176 |
| DMAC2L | distal membrane arm assembly component 2 like | -0.00501137 |
| LTF | lactotransferrin | -0.00495708 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00492226 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00489213 |
| GPX7 | glutathione peroxidase 7 | -0.00485347 |
| PLAT | plasminogen activator, tissue | -0.00484236 |
| RHOH | ras homolog family member H | -0.00479372 |
| TSPAN6 | tetraspanin 6 | -0.00474746 |
| TOX | thymocyte selection-associated high mobility group box | -0.00471633 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00467508 |
| NEBL | nebulette | -0.00466579 |
| S100A9 | S100 calcium binding protein A9 | -0.00465951 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00465524 |
| CFB | complement factor B | -0.00464749 |
| CHI3L2 | chitinase 3-like 2 | -0.00460549 |
| CREM | cAMP responsive element modulator | -0.0046046 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00460289 |
| DENND1B | DENN/MADD domain containing 1B | -0.00459173 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00457078 |
| KRT17 | keratin 17, type I | -0.00456959 |
| PEX2 | peroxisomal biogenesis factor 2 | -0.00456767 |
| CYBRD1 | cytochrome b reductase 1 | -0.0045668 |
| ACE2 | angiotensin I converting enzyme 2 | -0.00452771 |
| ORM1 | orosomucoid 1 | -0.00452272 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00451073 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00450433 |
| MSLN | mesothelin | -0.0044854 |
| KRT14 | keratin 14, type I | -0.00448269 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.00447908 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00447727 |
| STK17A | serine/threonine kinase 17a | -0.00447091 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00442774 |
| PMP2 | peripheral myelin protein 2 | -0.00439876 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.00438743 |
| GPM6A | glycoprotein M6A | -0.00437475 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.00437059 |
| CLCA4 | chloride channel accessory 4 | -0.00436941 |
| PLPP3 | phospholipid phosphatase 3 | -0.00436785 |
| SPP1 | secreted phosphoprotein 1 | -0.00436196 |
| KIAA0226L | KIAA0226-like | -0.00435487 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00434478 |
| FAM107A | family with sequence similarity 107, member A | -0.00434236 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00432222 |
| MUC16 | mucin 16, cell surface associated | -0.00431328 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.00425041 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0042332 |
| HAT1 | histone acetyltransferase 1 | -0.00422631 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00420436 |
| ZW10 | zw10 kinetochore protein | -0.00419765 |
| EGR2 | early growth response 2 | -0.00419166 |
| KIAA0125 | KIAA0125 | -0.0041653 |
| FAM102A | family with sequence similarity 102, member A | -0.0041615 |
| NCK1 | NCK adaptor protein 1 | -0.00415886 |
| CRYAB | crystallin, alpha B | -0.00415034 |
| KYNU | kynureninase | -0.00414408 |
| TPM4 | tropomyosin 4 | -0.00414341 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00412213 |
| CHEK1 | checkpoint kinase 1 | -0.00410161 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00407969 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00406963 |
| EDN3 | endothelin 3 | -0.00405878 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | -0.0040416 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00403768 |
| TFF1 | trefoil factor 1 | -0.00401515 |
| EMP3 | epithelial membrane protein 3 | -0.00400623 |
| SELENBP1 | selenium binding protein 1 | -0.0040041 |
| PLK1 | polo-like kinase 1 | -0.00400288 |
| TP53I3 | tumor protein p53 inducible protein 3 | -0.00400277 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00399282 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00398944 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00398866 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | -0.00398818 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00397332 |
| KIAA0100 | KIAA0100 | -0.00397277 |
| GRAMD4 | GRAM domain containing 4 | -0.0039701 |
| HMOX1 | heme oxygenase 1 | -0.00396882 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00395781 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00393221 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00392712 |
| NES | nestin | -0.0039119 |
| AMD1 | adenosylmethionine decarboxylase 1 | -0.00390282 |
| TSPAN3 | tetraspanin 3 | -0.00389933 |
| MALL | mal, T-cell differentiation protein-like | -0.0038972 |
| ZNF226 | zinc finger protein 226 | -0.00388555 |
| STC1 | stanniocalcin 1 | -0.00388043 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | -0.00387504 |
| TSC22D1 | TSC22 domain family, member 1 | -0.00387042 |
| SCRG1 | stimulator of chondrogenesis 1 | -0.00387035 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00386079 |
| SLC26A3 | solute carrier family 26 (anion exchanger), member 3 | -0.00385843 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0038515 |
| FBLN5 | fibulin 5 | -0.00383464 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00383225 |
| HMBS | hydroxymethylbilane synthase | -0.00382082 |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta | -0.00381565 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00380981 |
| PNMA2 | paraneoplastic Ma antigen 2 | -0.00379062 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00377392 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00375282 |
| FZD7 | frizzled class receptor 7 | -0.00374104 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.00373925 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma | -0.00373377 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.00372488 |
| ZNF580 | zinc finger protein 580 | -0.00372125 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00371274 |
| SLC35A5 | solute carrier family 35, member A5 | -0.00369883 |
| CPNE1 | copine I | -0.00369842 |
| GPR18 | G protein-coupled receptor 18 | -0.00368526 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00368048 |
| COPS7A | COP9 signalosome subunit 7A | -0.00367684 |
| GLCE | glucuronic acid epimerase | -0.00365782 |
| SCAND1 | SCAN domain containing 1 | -0.00364673 |
| AUTS2 | autism susceptibility candidate 2 | -0.00364367 |
| AASDHPPT | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | -0.00364266 |
| CCND1 | cyclin D1 | -0.00363033 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00362748 |
| TEX30 | testis expressed 30 | -0.00359976 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -0.00359908 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00359052 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00358714 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00358454 |
| SPA17 | sperm autoantigenic protein 17 | -0.00358194 |
| TTYH1 | tweety family member 1 | -0.00357907 |
| RNF19B | ring finger protein 19B | -0.00357357 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00357139 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00356999 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00356929 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00355795 |
| RAB8B | RAB8B, member RAS oncogene family | -0.00355101 |
| MAPK1 | mitogen-activated protein kinase 1 | -0.00355002 |
| ATP5MG | ATP synthase membrane subunit g | -0.00354544 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00354291 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00353735 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00353437 |
| STK17B | serine/threonine kinase 17b | -0.0035256 |
| COMMD10 | COMM domain containing 10 | -0.00350862 |
| CLIC5 | chloride intracellular channel 5 | -0.00350493 |
| SRGN | serglycin | -0.00350382 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -0.00350292 |
| SORD | sorbitol dehydrogenase | -0.00349431 |
| RDX | radixin | -0.00349417 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.0034916 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00348435 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00347869 |
| ZIC1 | Zic family member 1 | -0.00346851 |
| THYN1 | thymocyte nuclear protein 1 | -0.00346098 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00345963 |
| ACOT13 | acyl-CoA thioesterase 13 | -0.00345751 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00345097 |
| CLCA1 | chloride channel accessory 1 | -0.00344393 |
| GOLT1B | golgi transport 1B | -0.00344162 |
| GSTK1 | glutathione S-transferase kappa 1 | -0.00343997 |
| LMBRD1 | LMBR1 domain containing 1 | -0.00343391 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00343211 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00342593 |
| ICAM3 | intercellular adhesion molecule 3 | -0.00341834 |
| PLP1 | proteolipid protein 1 | -0.00341831 |
| GRHPR | glyoxylate reductase/hydroxypyruvate reductase | -0.00341777 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00340879 |
| NDC1 | NDC1 transmembrane nucleoporin | -0.00340625 |
| AK1 | adenylate kinase 1 | -0.0033908 |
| NOTCH1 | notch 1 | -0.00338676 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00338073 |
| FMO1 | flavin containing monooxygenase 1 | -0.00337963 |
| ANXA1 | annexin A1 | -0.00337935 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00337477 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | -0.00336443 |
| DEFB1 | defensin, beta 1 | -0.00336234 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0033574 |
| DAXX | death-domain associated protein | -0.00335158 |
| HOXA10 | homeobox A10 | -0.00332736 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00332528 |
| USE1 | unconventional SNARE in the ER 1 homolog (S. cerevisiae) | -0.0033112 |
| KLHL7 | kelch-like family member 7 | -0.00330092 |
| GPM6B | glycoprotein M6B | -0.00329956 |
| GCG | glucagon | -0.00329373 |
| THY1 | Thy-1 cell surface antigen | -0.0032911 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00328821 |
| SLA | Src-like-adaptor | -0.00328279 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00328265 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00327253 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00327077 |
| OLFML2A | olfactomedin-like 2A | -0.00326632 |
| FABP1 | fatty acid binding protein 1, liver | -0.00326625 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00326385 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00326166 |
| PIP | prolactin-induced protein | -0.00326129 |
| PPA1 | pyrophosphatase (inorganic) 1 | -0.00325449 |
| DCTN6 | dynactin 6 | -0.00325374 |
| ERF | Ets2 repressor factor | -0.00324723 |
| PUS3 | pseudouridylate synthase 3 | -0.00324661 |
| S100A7 | S100 calcium binding protein A7 | -0.00324226 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.0032393 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00323866 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.00323476 |
| SESN1 | sestrin 1 | -0.00323399 |
| CCDC90B | coiled-coil domain containing 90B | -0.00322521 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00321906 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00321385 |
| DOK5 | docking protein 5 | -0.00320925 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | -0.00320527 |
| ERGIC3 | ERGIC and golgi 3 | -0.00319821 |
| PRNP | prion protein | -0.00319345 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00319332 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.0031907 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | -0.00318512 |
| STOM | stomatin | -0.00318507 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.00317698 |
| MUC4 | mucin 4, cell surface associated | -0.0031743 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00317034 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | -0.00316364 |
| CD58 | CD58 molecule | -0.0031528 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | -0.00313911 |
| CRP | C-reactive protein, pentraxin-related | -0.0031278 |
| OPHN1 | oligophrenin 1 | -0.0031174 |
