MMP2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description matrix metallopeptidase 2|This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014] (NCBI Entrez Gene Database, 4313)
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Genes

408 genes differentially expressed following the MMP2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
DYNAP dynactin associated protein 3.28147
SPNS2 spinster homolog 2 (Drosophila) 3.28147
KCNK15 potassium channel, two pore domain subfamily K, member 15 3.28147
PTGER4 prostaglandin E receptor 4 (subtype EP4) 3.28147
CFAP45 cilia and flagella associated protein 45 3.28147
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 3.28147
SLITRK1 SLIT and NTRK-like family, member 1 3.28147
CCDC121 coiled-coil domain containing 121 3.28147
KLK4 kallikrein-related peptidase 4 3.28147
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.28147
DSG3 desmoglein 3 3.28147
WFDC1 WAP four-disulfide core domain 1 3.28147
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 3.28147
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.28147
SPATA46 spermatogenesis associated 46 3.28147
PTPRQ protein tyrosine phosphatase, receptor type, Q 3.28147
CD22 CD22 molecule 3.28147
SPMIP3 sperm microtubule inner protein 3 3.28147
MEOX2 mesenchyme homeobox 2 3.28147
MRPL53 mitochondrial ribosomal protein L53 3.28147
LGALS7B lectin, galactoside-binding, soluble, 7B 3.28147
OR56A3 olfactory receptor, family 56, subfamily A, member 3 3.28147
CHCT1 CHD1 helical C-terminal domain containing 1 3.28147
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 3.28147
SLC38A3 solute carrier family 38, member 3 3.28147
APOA1 apolipoprotein A-I 3.28147
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 3.16545
SIX1 SIX homeobox 1 3.16545
TMPRSS11A transmembrane protease, serine 11A 3.16545
TEX101 testis expressed 101 3.16545
IL11RA interleukin 11 receptor, alpha 3.16545
SIX2 SIX homeobox 2 3.16545
CLDN2 claudin 2 3.16545
GJA5 gap junction protein, alpha 5, 40kDa 3.16545
DMP1 dentin matrix acidic phosphoprotein 1 3.16545
FAM153A family with sequence similarity 153, member A 3.16545
PTPRB protein tyrosine phosphatase, receptor type, B 3.16545
FAM170A family with sequence similarity 170, member A 3.16545
SECTM1 secreted and transmembrane 1 3.16545
FOXD1 forkhead box D1 3.16545
MYO7B myosin VIIB 3.16545
GPR21 G protein-coupled receptor 21 3.16545
CARD16 caspase recruitment domain family, member 16 3.16545
HCST hematopoietic cell signal transducer 3.16545
ETNK2 ethanolamine kinase 2 3.16545
OCSTAMP osteoclast stimulatory transmembrane protein 3.16545
MSANTD1 Myb/SANT-like DNA-binding domain containing 1 3.16545
SHE Src homology 2 domain containing E 3.16545
COPZ2 coatomer protein complex, subunit zeta 2 3.16545
FAM216B family with sequence similarity 216, member B 3.16545
ATOH7 atonal homolog 7 (Drosophila) 3.16545
MYO1A myosin IA 3.16545
GALR3 galanin receptor 3 3.16545
TRPV5 transient receptor potential cation channel, subfamily V, member 5 3.16545
MYOM3 myomesin 3 3.16545
SCN2B sodium channel, voltage gated, type II beta subunit 3.16545
SPINK4 serine peptidase inhibitor, Kazal type 4 3.16545
TSGA13 testis specific, 13 3.16545
PRSS41 protease, serine, 41 3.16545
SOX18 SRY (sex determining region Y)-box 18 3.16545
MISP mitotic spindle positioning 3.16545
LRRC53 leucine rich repeat containing 53 3.16545
CSTL1 cystatin-like 1 3.16545
TYRP1 tyrosinase-related protein 1 3.16545
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 3.16545
SLC35G6 solute carrier family 35, member G6 3.16545
LOC114841035 uncharacterized LOC114841035 3.16545
GK3 glycerol kinase 3 3.16545
TMEM275 transmembrane protein 275 3.16545
CCDC9B coiled-coil domain containing 9B 3.16545
GIPC3 GIPC PDZ domain containing family, member 3 3.16545
ZNF726 zinc finger protein 726 3.16545
MCHR2 melanin-concentrating hormone receptor 2 3.16545
ROPN1B rhophilin associated tail protein 1B 3.16545
CAPN9 calpain 9 3.16545
AHCYL1 adenosylhomocysteinase-like 1 3.16545
FMO2 flavin containing monooxygenase 2 (non-functional) 3.16545
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 3.16545
RTL9 retrotransposon Gag like 9 3.16545
MSANTD5 Myb/SANT DNA binding domain containing 5 3.16545
HSFX4 heat shock transcription factor family, X-linked member 4 3.16545
PNMA6F PNMA family member 6F 3.16545
NOTCH2NLB notch 2 N-terminal like B 3.16545
LOC124903233 uncharacterized LOC124903233 3.16545
SMIM45 small integral membrane protein 45 3.16545
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 3.16545
IQCN IQ motif containing N 3.16545
SPEM2 SPEM family member 2 3.16545
DEFB131B defensin beta 131B 3.16545
SPMIP9 sperm microtubule inner protein 9 3.16545
RTL5 retrotransposon Gag like 5 3.16545
GSG1L GSG1-like 3.16545
SMLR1 small leucine-rich protein 1 3.16545
S100B S100 calcium binding protein B 3.16545
NPFF neuropeptide FF-amide peptide precursor 3.16545
C1QL2 complement component 1, q subcomponent-like 2 3.16545
OR2A12 olfactory receptor, family 2, subfamily A, member 12 3.16545
ZIC4 Zic family member 4 3.16545
GOLGA7B golgin A7 family, member B 3.16545
RHCG Rh family, C glycoprotein 3.16545
CATSPER3 cation channel, sperm associated 3 3.16545
ANXA10 annexin A10 3.16545
C3ORF80 chromosome 3 open reading frame 80 3.16545
CHRD chordin 3.16545
TACR2 tachykinin receptor 2 3.16545
SAA2 serum amyloid A2 3.16545
TBC1D3L TBC1 domain family, member 3L 3.16545
TBX10 T-box 10 3.16545
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 3.16545
GATA4 GATA binding protein 4 3.16545
OR7D2 olfactory receptor, family 7, subfamily D, member 2 3.16545
KL klotho 3.16545
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 3.16545
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.16545
CNTN6 contactin 6 3.16545
ABHD15 abhydrolase domain containing 15 3.16545
ADIG adipogenin 3.16545
NXPE4 neurexophilin and PC-esterase domain family, member 4 3.16545
KRTAP5-2 keratin associated protein 5-2 3.16545
DNAH12 dynein, axonemal, heavy chain 12 3.16545
NUTM2F NUT family member 2F 3.16545
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 3.16545
DAND5 DAN domain family member 5, BMP antagonist 3.16545
FITM1 fat storage-inducing transmembrane protein 1 3.16545
CLEC4G C-type lectin domain family 4, member G 3.16545
CYS1 cystin 1 3.16545
FIBIN fin bud initiation factor homolog (zebrafish) 3.16545
RERGL RERG/RAS-like 3.16545
EMP1 epithelial membrane protein 1 3.16545
NUPR1 nuclear protein, transcriptional regulator, 1 3.16545
SULT1C3 sulfotransferase family, cytosolic, 1C, member 3 3.16545
CER1 cerberus 1, DAN family BMP antagonist 3.16545
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.16545
PYHIN1 pyrin and HIN domain family, member 1 3.16545
RTN4RL1 reticulon 4 receptor-like 1 3.16545
NPBWR1 neuropeptides B/W receptor 1 3.16545
LPAR5 lysophosphatidic acid receptor 5 3.16545
EXTL1 exostosin-like glycosyltransferase 1 3.16545
UBQLNL ubiquilin-like 3.16545
NIM1K NIM1 serine/threonine protein kinase 3.16545
DQX1 DEAQ box RNA-dependent ATPase 1 3.16545
CCDC154 coiled-coil domain containing 154 3.16545
NPIPB15 nuclear pore complex interacting protein family, member B15 3.16545
STAB1 stabilin 1 3.16545
KLHL6 kelch-like family member 6 3.16545
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 3.16545
WFDC6 WAP four-disulfide core domain 6 3.16545
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 3.16545
NPFFR1 neuropeptide FF receptor 1 3.16545
OR56A4 olfactory receptor, family 56, subfamily A, member 4 3.16545
SERINC4 serine incorporator 4 3.16545
ECM1 extracellular matrix protein 1 3.16545
UTS2B urotensin 2B 3.16545
CALR3 calreticulin 3 3.16545
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 3.16545
KCNK16 potassium channel, two pore domain subfamily K, member 16 3.16545
LRRC43 leucine rich repeat containing 43 3.16545
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 3.16545
AOC1 amine oxidase, copper containing 1 3.16545
MSMP microseminoprotein, prostate associated 3.16545
POU4F1 POU class 4 homeobox 1 3.16545
IRX5 iroquois homeobox 5 3.16545
OR6B1 olfactory receptor, family 6, subfamily B, member 1 3.16545
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 3.16545
CCDC78 coiled-coil domain containing 78 3.16545
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 3.16545
VMO1 vitelline membrane outer layer 1 homolog (chicken) 3.16545
NR2F2 nuclear receptor subfamily 2, group F, member 2 3.16545
GOLGA8M golgin A8 family, member M 3.16545
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 3.16545
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.16545
ANGPTL6 angiopoietin-like 6 3.16545
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 3.16545
TMPRSS12 transmembrane (C-terminal) protease, serine 12 3.16545
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 3.16545
DMRTC2 DMRT-like family C2 3.16545
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 3.16545
PENK proenkephalin 3.16545
SOSTDC1 sclerostin domain containing 1 3.16545
CGA glycoprotein hormones, alpha polypeptide 3.16545
TGM4 transglutaminase 4 3.16545
PGR progesterone receptor 3.16545
PADI6 peptidyl arginine deiminase, type VI 3.16545
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 3.13028
ZC2HC1C zinc finger, C2HC-type containing 1C 3.05869
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 3.0475
PCDHA13 protocadherin alpha 13 3.0475
GNPAT glyceronephosphate O-acyltransferase 3.01963
ZNF710 zinc finger protein 710 2.8702
MRPS31 mitochondrial ribosomal protein S31 2.82832
E2F7 E2F transcription factor 7 2.66338
RASL11A RAS-like, family 11, member A 2.63411
ZSCAN32 zinc finger and SCAN domain containing 32 2.5338
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 2.52074
PRDX5 peroxiredoxin 5 2.51199
PDZD9 PDZ domain containing 9 2.51199
HORMAD2 HORMA domain containing 2 2.51199
INTS7 integrator complex subunit 7 2.51199
LUC7L3 LUC7-like 3 (S. cerevisiae) 2.50339
SHARPIN SHANK-associated RH domain interactor 2.49568
MARCHF7 membrane associated ring-CH-type finger 7 2.49522
KIF6 kinesin family member 6 2.46343
CHERP calcium homeostasis endoplasmic reticulum protein 2.44318
SPMIP10 sperm microtubule inner protein 10 2.42115
SETMAR SET domain and mariner transposase fusion gene 2.41755
RASGEF1B RasGEF domain family, member 1B 2.41599
MZT2A mitotic spindle organizing protein 2A 2.39801
TRAK2 trafficking protein, kinesin binding 2 2.37548
STIM1 stromal interaction molecule 1 2.3694
SCN11A sodium channel, voltage gated, type XI alpha subunit 2.36214
LIMK1 LIM domain kinase 1 2.36214
PCDH18 protocadherin 18 2.35912
OLFM2 olfactomedin 2 2.3557
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 2.34082
TMEM191C transmembrane protein 191C 2.33507
OCM oncomodulin 2.33507
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 2.33507
SIX3 SIX homeobox 3 2.33507
UBXN2B UBX domain protein 2B 2.3337
VWA2 von Willebrand factor A domain containing 2 2.31952
AFF2 AF4/FMR2 family, member 2 2.30426
ARCN1 archain 1 2.2843
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 2.28301
METTL23 methyltransferase like 23 2.22838
LBH limb bud and heart development 2.20992
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.20603
LYRM1 LYR motif containing 1 2.2028
NOTCH2NLA notch 2 N-terminal like A 2.2003
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 2.17758
NCEH1 neutral cholesterol ester hydrolase 1 2.17522
USP28 ubiquitin specific peptidase 28 2.17264
NRSN2 neurensin 2 2.17209
FGGY FGGY carbohydrate kinase domain containing 2.15802
DSCAM Down syndrome cell adhesion molecule 2.15386
FAM234B family with sequence similarity 234 member B 2.15367
SETD1B SET domain containing 1B 2.15043
SCAND3 SCAN domain containing 3 2.14606
BTD biotinidase 2.14166
VAMP7 vesicle-associated membrane protein 7 2.14051
PPP1R15B protein phosphatase 1, regulatory subunit 15B 2.13947
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.12532
ADH6 alcohol dehydrogenase 6 (class V) 2.12532
ADAP1 ArfGAP with dual PH domains 1 2.12532
GTF2A1L general transcription factor IIA, 1-like 2.12532
XK X-linked Kx blood group 2.12532
CPM carboxypeptidase M 2.12532
ZFP92 ZFP92 zinc finger protein 2.12532
RGN regucalcin 2.12532
RAB12 RAB12, member RAS oncogene family 2.12532
TUBB4A tubulin, beta 4A class IVa 2.10764
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 2.10764
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 2.10764
C15ORF40 chromosome 15 open reading frame 40 2.1048
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.10443
BCL7B B-cell CLL/lymphoma 7B 2.10443
CCNC cyclin C 2.10443
C2ORF69 chromosome 2 open reading frame 69 2.09767
CLP1 cleavage and polyadenylation factor I subunit 1 2.09307
PDPN podoplanin 2.08625
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 2.08179
DLC1 DLC1 Rho GTPase activating protein 2.08179
FGF14 fibroblast growth factor 14 2.08179
TENM1 teneurin transmembrane protein 1 2.05325
POLR2G polymerase (RNA) II (DNA directed) polypeptide G 2.02346
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like 2.01775

decreased expression

Symbol Name Standardized Value
LRATD1 LRAT domain containing 1 -3.28147
RBM44 RNA binding motif protein 44 -3.28147
C17ORF100 chromosome 17 open reading frame 100 -3.28147
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae) -3.28147
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -3.28147
TOM1L2 target of myb1-like 2 (chicken) -3.28147
ACSL6 acyl-CoA synthetase long-chain family member 6 -3.28147
UCMA upper zone of growth plate and cartilage matrix associated -3.28147
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 -3.28147
MGARP mitochondria-localized glutamic acid-rich protein -3.28147
PIRT phosphoinositide-interacting regulator of transient receptor potential channels -3.28147
ROPN1L rhophilin associated tail protein 1-like -3.16545
RPA4 replication protein A4, 30kDa -3.16545
KLK6 kallikrein-related peptidase 6 -3.16545
PNPLA8 patatin-like phospholipase domain containing 8 -3.16545
LTF lactotransferrin -3.16545
EMILIN1 elastin microfibril interfacer 1 -3.16545
CD80 CD80 molecule -3.16545
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -3.16545
F10 coagulation factor X -3.16545
SFN stratifin -3.16545
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -3.16545
LMNTD2 lamin tail domain containing 2 -3.16545
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -3.16545
SLC23A3 solute carrier family 23, member 3 -3.16545
FLACC1 flagellum associated containing coiled-coil domains 1 -3.16545
PRKN parkin RBR E3 ubiquitin protein ligase -3.16545
PTX3 pentraxin 3, long -3.16545
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 -3.16545
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 -3.16545
DPPA3 developmental pluripotency associated 3 -3.16545
SVOP SV2 related protein homolog (rat) -3.16545
HSPB6 heat shock protein, alpha-crystallin-related, B6 -3.16545
ANAPC2 anaphase promoting complex subunit 2 -3.16545
C6ORF118 chromosome 6 open reading frame 118 -3.16545
HES7 hes family bHLH transcription factor 7 -3.16545
LHX6 LIM homeobox 6 -3.16545
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -3.16545
DAW1 dynein assembly factor with WDR repeat domains 1 -3.16545
CD160 CD160 molecule -3.16545
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 -3.12088
MMP2 matrix metallopeptidase 2 -3.08737
INPP5J inositol polyphosphate-5-phosphatase J -3.05931
SPATA18 spermatogenesis associated 18 -3.0511
MANEAL mannosidase, endo-alpha-like -3.0511
UBL4A ubiquitin-like 4A -3.01485
PDK2 pyruvate dehydrogenase kinase, isozyme 2 -3.01083
CFAP300 cilia and flagella associated protein 300 -2.82832
MYO1H myosin IH -2.8186
CD99 CD99 molecule -2.77882
IGSF10 immunoglobulin superfamily, member 10 -2.75931
HMGN2 high mobility group nucleosomal binding domain 2 -2.75831
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -2.75173
CCN2 cellular communication network factor 2 -2.73539
DGKQ diacylglycerol kinase, theta 110kDa -2.70768
SBSPON somatomedin B and thrombospondin, type 1 domain containing -2.70768
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -2.67004
HEATR1 HEAT repeat containing 1 -2.65339
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -2.65335
QTRT1 queuine tRNA-ribosyltransferase 1 -2.63547
RCSD1 RCSD domain containing 1 -2.633
RASL10B RAS-like, family 10, member B -2.62647
CNTNAP5 contactin associated protein-like 5 -2.59098
TXNIP thioredoxin interacting protein -2.56269
PCDHA9 protocadherin alpha 9 -2.5548
ZSCAN1 zinc finger and SCAN domain containing 1 -2.5548
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -2.5548
MANSC1 MANSC domain containing 1 -2.5548
TULP2 tubby like protein 2 -2.54793
SYCP3 synaptonemal complex protein 3 -2.54793
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -2.51387
KREMEN1 kringle containing transmembrane protein 1 -2.49568
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -2.46982
CFAP410 cilia and flagella associated protein 410 -2.46982
DCAF5 DDB1 and CUL4 associated factor 5 -2.41705
BRIX1 BRX1, biogenesis of ribosomes -2.40665
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -2.38831
MME membrane metallo-endopeptidase -2.37
PCDHGC3 protocadherin gamma subfamily C, 3 -2.36679
FBXO48 F-box protein 48 -2.36679
COG3 component of oligomeric golgi complex 3 -2.36328
GJA1 gap junction protein, alpha 1, 43kDa -2.36142
SRRM1 serine/arginine repetitive matrix 1 -2.35912
ACOT11 acyl-CoA thioesterase 11 -2.35912
ANG angiogenin, ribonuclease, RNase A family, 5 -2.35637
ABLIM2 actin binding LIM protein family, member 2 -2.35637
HES6 hes family bHLH transcription factor 6 -2.3337
GCLM glutamate-cysteine ligase, modifier subunit -2.3337
NEIL1 nei endonuclease VIII-like 1 (E. coli) -2.3321
HSPB2 heat shock 27kDa protein 2 -2.3204
FZD9 frizzled class receptor 9 -2.3204
RAB27B RAB27B, member RAS oncogene family -2.3204
SYT15B synaptotagmin 15B -2.3204
HLA-DRA major histocompatibility complex, class II, DR alpha -2.3204
MRPL50 mitochondrial ribosomal protein L50 -2.30875
SETX senataxin -2.28877
MED18 mediator complex subunit 18 -2.28826
CA5B carbonic anhydrase VB, mitochondrial -2.2843
SRSF9 serine/arginine-rich splicing factor 9 -2.28301
TIMP4 TIMP metallopeptidase inhibitor 4 -2.2771
RXFP1 relaxin/insulin-like family peptide receptor 1 -2.25948
KIF21A kinesin family member 21A -2.25634
PRAF2 PRA1 domain family, member 2 -2.25029
BRD9 bromodomain containing 9 -2.25029
HDDC3 HD domain containing 3 -2.24551
AK4 adenylate kinase 4 -2.24484
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -2.24484
TZMP1 transition zone microprotein 1 -2.24306
OGFRL1 opioid growth factor receptor-like 1 -2.22265
AP1M1 adaptor-related protein complex 1, mu 1 subunit -2.21328
ZW10 zw10 kinetochore protein -2.20992
FANCE Fanconi anemia, complementation group E -2.20992
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -2.20638
PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 -2.20638
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha) -2.18933
BTF3 basic transcription factor 3 -2.17209
GPR161 G protein-coupled receptor 161 -2.15802
CARNMT1 carnosine N-methyltransferase 1 -2.14697
ADD3 adducin 3 (gamma) -2.14606
PAPOLA poly(A) polymerase alpha -2.14082
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 -2.13654
MZF1 myeloid zinc finger 1 -2.13654
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.13325
OPLAH 5-oxoprolinase (ATP-hydrolysing) -2.13123
GAB3 GRB2-associated binding protein 3 -2.13123
HMG20A high mobility group 20A -2.12532
PAIP2 poly(A) binding protein interacting protein 2 -2.10764
RTKN rhotekin -2.10443
MTX1 metaxin 1 -2.10354
FRG1 FSHD region gene 1 -2.10156
PIPOX pipecolic acid oxidase -2.09307
TRMT5 tRNA methyltransferase 5 -2.08742
PMPCA peptidase (mitochondrial processing) alpha -2.08591
LDHD lactate dehydrogenase D -2.07104
NCAN neurocan -2.07104
LDLRAD3 low density lipoprotein receptor class A domain containing 3 -2.06751
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -2.06751
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -2.06129
ABHD3 abhydrolase domain containing 3 -2.05325
LRRC58 leucine rich repeat containing 58 -2.03005
CHD9NB CHD9 neighbor -2.01775
ZBED8 zinc finger, BED-type containing 8 -2.01748
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like -2.01734