MMRN1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description multimerin 1|Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 22915)
External Link https://ncbi.nlm.nih.gov/gene/22915
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Genes

496 genes differentially expressed following the MMRN1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
S100P S100 calcium binding protein P 0.016617
SYNGR3 synaptogyrin 3 0.0137494
LYZ lysozyme 0.0133587
SSBP2 single-stranded DNA binding protein 2 0.0123804
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0123644
MAGEA3 melanoma antigen family A3 0.0116932
IFI27 interferon, alpha-inducible protein 27 0.0111738
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.0110746
HOXB7 homeobox B7 0.0110651
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0109033
SMC1A structural maintenance of chromosomes 1A 0.0107475
QPRT quinolinate phosphoribosyltransferase 0.0102367
INAVA innate immunity activator 0.0101966
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00998285
COG7 component of oligomeric golgi complex 7 0.00996646
MAGEA12 melanoma antigen family A12 0.00966399
RNASET2 ribonuclease T2 0.00947672
S100A7 S100 calcium binding protein A7 0.00935073
CTSC cathepsin C 0.00934892
AKAP8 A kinase (PRKA) anchor protein 8 0.00925714
TPM4 tropomyosin 4 0.00913992
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.0090696
CLTB clathrin, light chain B 0.00904434
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00886111
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00883768
DMD dystrophin 0.00878823
MAL mal, T-cell differentiation protein 0.00873693
LCN2 lipocalin 2 0.00872429
NELL2 NEL-like 2 (chicken) 0.00864561
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.00863235
LRRN3 leucine rich repeat neuronal 3 0.00863046
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00859376
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00859093
AQP3 aquaporin 3 (Gill blood group) 0.00859085
PEG3 paternally expressed 3 0.00858166
CSTA cystatin A (stefin A) 0.00849537
ACTG2 actin, gamma 2, smooth muscle, enteric 0.00838448
FGF13 fibroblast growth factor 13 0.00826171
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00819571
PDZK1IP1 PDZK1 interacting protein 1 0.00816753
ITGA6 integrin, alpha 6 0.00816472
GPC3 glypican 3 0.00810504
COL15A1 collagen, type XV, alpha 1 0.0079984
GUCY2C guanylate cyclase 2C 0.00798536
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00794971
ITK IL2-inducible T-cell kinase 0.00787733
GBP2 guanylate binding protein 2, interferon-inducible 0.00786099
NID1 nidogen 1 0.00785
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00784991
RSL1D1 ribosomal L1 domain containing 1 0.00784129
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00778543
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00777558
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00773046
GYPC glycophorin C (Gerbich blood group) 0.00769882
IFRD2 interferon-related developmental regulator 2 0.00768358
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00755737
PUDP pseudouridine 5'-phosphatase 0.00753795
ARHGAP15 Rho GTPase activating protein 15 0.00753156
IFI16 interferon, gamma-inducible protein 16 0.00749787
IL32 interleukin 32 0.00748427
BST2 bone marrow stromal cell antigen 2 0.00746684
HOPX HOP homeobox 0.0074534
SNX10 sorting nexin 10 0.00743368
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.007413
C7 complement component 7 0.00729106
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 0.00727612
CALB1 calbindin 1, 28kDa 0.00719701
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00719432
CLEC2B C-type lectin domain family 2, member B 0.00714464
GNS glucosamine (N-acetyl)-6-sulfatase 0.00711139
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00707849
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00705486
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00700761
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00699059
AKAP12 A kinase (PRKA) anchor protein 12 0.00698374
GSTM3 glutathione S-transferase mu 3 (brain) 0.00696654
FZD6 frizzled class receptor 6 0.00694944
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00694826
PLLP plasmolipin 0.00694187
TMX4 thioredoxin-related transmembrane protein 4 0.00692713
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00688445
ADCY3 adenylate cyclase 3 0.00684395
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.00682883
RGS4 regulator of G-protein signaling 4 0.0067767
ZNF652 zinc finger protein 652 0.00676009
IQGAP2 IQ motif containing GTPase activating protein 2 0.00675379
MYO1C myosin IC 0.00674741
ACAA1 acetyl-CoA acyltransferase 1 0.00673798
ANXA3 annexin A3 0.00667616
RNF167 ring finger protein 167 0.00667302
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0066367
WIF1 WNT inhibitory factor 1 0.00662796
GCH1 GTP cyclohydrolase 1 0.00662309
RRM2 ribonucleotide reductase M2 0.00661908
SRP72 signal recognition particle 72kDa 0.00658887
VWF von Willebrand factor 0.00658334
GPI glucose-6-phosphate isomerase 0.00658201
HEPH hephaestin 0.00658177
DLK1 delta-like 1 homolog (Drosophila) 0.00656221
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00653991
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.00653539
GPR171 G protein-coupled receptor 171 0.00653251
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00651
PDZD2 PDZ domain containing 2 0.00650328
LAPTM4B lysosomal protein transmembrane 4 beta 0.00644856
ATF3 activating transcription factor 3 0.00643326
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00643149
CADM1 cell adhesion molecule 1 0.00643032
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00639872
ACOT7 acyl-CoA thioesterase 7 0.00639551
ISG15 ISG15 ubiquitin-like modifier 0.00638206
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.0063456
BRCA1 breast cancer 1, early onset 0.00633909
TMED3 transmembrane emp24 protein transport domain containing 3 0.00633595
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00632971
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00632809
TNIP1 TNFAIP3 interacting protein 1 0.00632411
CA2 carbonic anhydrase II 0.00630972
HIST3H2A histone cluster 3, H2a 0.00628213
KDM6A lysine (K)-specific demethylase 6A 0.0062649
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00622866
RPN2 ribophorin II 0.00622862
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 0.00622016
FILIP1L filamin A interacting protein 1-like 0.0061917
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.00617445
RAP1B RAP1B, member of RAS oncogene family 0.00616954
VLDLR very low density lipoprotein receptor 0.00615098
PLBD1 phospholipase B domain containing 1 0.00614296
SNAP23 synaptosomal-associated protein, 23kDa 0.00611546
DEFB1 defensin, beta 1 0.00609609
KRT13 keratin 13, type I 0.00609588
FABP6 fatty acid binding protein 6, ileal 0.00609579
ZNF185 zinc finger protein 185 (LIM domain) 0.00609279
RBMS1 RNA binding motif, single stranded interacting protein 1 0.00607856
WASHC4 WASH complex subunit 4 0.00603799
KIF2C kinesin family member 2C 0.00603702
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00602768
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.00601753
NDN necdin, melanoma antigen (MAGE) family member 0.00600365
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00599782
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.00599457
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00597357
PRKCH protein kinase C, eta 0.00596411
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00596003
SPRR3 small proline-rich protein 3 0.00593853
CCNG1 cyclin G1 0.00593433
MX2 MX dynamin-like GTPase 2 0.00592753
KYAT3 kynurenine aminotransferase 3 0.00591261
L1CAM L1 cell adhesion molecule 0.00590217
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.00589148
TFRC transferrin receptor 0.00586594
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00585926
HBB hemoglobin, beta 0.0058556
HSPA8 heat shock 70kDa protein 8 0.00584155
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00583053
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00582857
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.0058189
TCTA T-cell leukemia translocation altered 0.00581204
ELF1 E74-like factor 1 (ets domain transcription factor) 0.005798
VNN1 vanin 1 0.0057601
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00575656
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00570463
RIOX2 ribosomal oxygenase 2 0.00569005
TMPRSS4 transmembrane protease, serine 4 0.00568673
XIC X chromosome inactivation center 0.0056726
FLNA filamin A, alpha 0.00565139
SAMD9 sterile alpha motif domain containing 9 0.00560628
KYNU kynureninase 0.00559802
STOM stomatin 0.00559233
FMO1 flavin containing monooxygenase 1 0.00557917
HOXB6 homeobox B6 0.00557326
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00556941
CTSS cathepsin S 0.00556327
ACP1 acid phosphatase 1, soluble 0.00551989
COL4A5 collagen, type IV, alpha 5 0.00551666
CNN2 calponin 2 0.00549766
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.00548651
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00548352
COL3A1 collagen, type III, alpha 1 0.00547809
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.00547757
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.00547334
STATH statherin 0.00546239
CST3 cystatin C 0.00546034
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 0.0054552
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.005455
CCL14 chemokine (C-C motif) ligand 14 0.00545012
ELL2 elongation factor, RNA polymerase II, 2 0.00543707
PRF1 perforin 1 (pore forming protein) 0.0054296
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 0.00540874
S100A9 S100 calcium binding protein A9 0.00540042
C6ORF48 chromosome 6 open reading frame 48 0.00539458
PRAME preferentially expressed antigen in melanoma 0.00535847
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.0053488
DAZAP2 DAZ associated protein 2 0.00534717
SKAP2 src kinase associated phosphoprotein 2 0.00533329
PITX1 paired-like homeodomain 1 0.0053266
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.00531257
PRMT5 protein arginine methyltransferase 5 0.0053112
MGAM maltase-glucoamylase 0.00530772
IL2RB interleukin 2 receptor, beta 0.00528714
LARP1 La ribonucleoprotein domain family, member 1 0.00525338
MOAP1 modulator of apoptosis 1 0.00523718
CPD carboxypeptidase D 0.00523545
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00519937
CDC42 cell division cycle 42 0.00519449
MVP major vault protein 0.00518687
CANX calnexin 0.00518476
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.00517803
MYRF myelin regulatory factor 0.00517603
EDN3 endothelin 3 0.00517569
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.0051753
PSAT1 phosphoserine aminotransferase 1 0.00517321
CTSH cathepsin H 0.00517171
AK4 adenylate kinase 4 0.00517082
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00516933
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 0.00516256
ELAVL1 ELAV like RNA binding protein 1 0.00516083
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.0051552
VAMP5 vesicle-associated membrane protein 5 0.00515448
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00514951
PRSS21 protease, serine, 21 (testisin) 0.00514257
SEPP1 selenoprotein P, plasma, 1 0.00513688
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00512041
NLRP2 NLR family, pyrin domain containing 2 0.00510572
DONSON downstream neighbor of SON 0.00507087
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00507039
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00506799
MICB MHC class I polypeptide-related sequence B 0.00506722
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00506222
SIRPG signal-regulatory protein gamma 0.00505657
IL6ST interleukin 6 signal transducer 0.00505231
SP140L SP140 nuclear body protein-like 0.00505216
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00504787
AIM2 absent in melanoma 2 0.00504773
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00504621
PUM2 pumilio RNA-binding family member 2 0.00503597
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00503593
PRB1 proline-rich protein BstNI subfamily 1 0.00503187
TCF21 transcription factor 21 0.00502827
ITM2A integral membrane protein 2A 0.0050191
OXA1L oxidase (cytochrome c) assembly 1-like 0.00501601
COCH cochlin 0.00501253
SPRR2B small proline-rich protein 2B 0.00500931
NIBAN1 niban apoptosis regulator 1 0.00500534
TFDP1 transcription factor Dp-1 0.0050043
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.00499834
CNPPD1 cyclin Pas1/PHO80 domain containing 1 0.00499044
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00498903
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.00497687

decreased expression

Symbol Name Standardized Value
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0157122
MAP7 microtubule-associated protein 7 -0.014585
ZBTB18 zinc finger and BTB domain containing 18 -0.0135501
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0135205
JCHAIN joining chain of multimeric IgA and IgM -0.0122815
KDM5D lysine (K)-specific demethylase 5D -0.0121322
APOD apolipoprotein D -0.0120548
RRAGA Ras-related GTP binding A -0.0110735
NOTCH2NL notch 2 N-terminal like -0.010883
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.0104238
BASP1 brain abundant, membrane attached signal protein 1 -0.0103017
ZDHHC6 zinc finger, DHHC-type containing 6 -0.010003
TFF3 trefoil factor 3 (intestinal) -0.0099847
WDR7 WD repeat domain 7 -0.00986773
ZBTB20 zinc finger and BTB domain containing 20 -0.00985443
SCGB1D2 secretoglobin, family 1D, member 2 -0.00974966
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00973838
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00953432
ADIRF adipogenesis regulatory factor -0.00942214
COPS7A COP9 signalosome subunit 7A -0.00941255
MMP1 matrix metallopeptidase 1 -0.00900041
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00888593
LPAR1 lysophosphatidic acid receptor 1 -0.00884454
TPSAB1 tryptase alpha/beta 1 -0.00876659
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00872504
PEG10 paternally expressed 10 -0.00866554
PITX3 paired-like homeodomain 3 -0.0085992
MBL2 mannose-binding lectin (protein C) 2, soluble -0.0085689
GAS6 growth arrest-specific 6 -0.00843206
CNOT7 CCR4-NOT transcription complex, subunit 7 -0.0083284
PDLIM3 PDZ and LIM domain 3 -0.00832418
PTK2B protein tyrosine kinase 2 beta -0.00827276
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00822542
DSP desmoplakin -0.00821128
CTBP2 C-terminal binding protein 2 -0.00811204
AKR1C3 aldo-keto reductase family 1, member C3 -0.00810963
TPD52 tumor protein D52 -0.0080829
GAL galanin/GMAP prepropeptide -0.00805676
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00796484
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00796216
SCGB2A2 secretoglobin, family 2A, member 2 -0.00793557
PDE4DIP phosphodiesterase 4D interacting protein -0.00783305
CDC20 cell division cycle 20 -0.0078319
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00782427
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00781024
SPON2 spondin 2, extracellular matrix protein -0.00779728
SCAF4 SR-related CTD-associated factor 4 -0.00776159
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00771777
MLPH melanophilin -0.0076538
PDLIM5 PDZ and LIM domain 5 -0.00763343
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00762583
PLAAT3 phospholipase A and acyltransferase 3 -0.00761786
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00759378
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00758569
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00757005
PLIN2 perilipin 2 -0.00756766
OLFM4 olfactomedin 4 -0.00743555
PTPRD protein tyrosine phosphatase, receptor type, D -0.00740761
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00737337
HTRA1 HtrA serine peptidase 1 -0.00734412
SIRT3 sirtuin 3 -0.00731694
IPO13 importin 13 -0.0072956
CYB5A cytochrome b5 type A (microsomal) -0.00728205
ENO3 enolase 3 (beta, muscle) -0.00728184
GPX1 glutathione peroxidase 1 -0.00725263
VIM vimentin -0.00723975
TNC tenascin C -0.0072387
MYBPC1 myosin binding protein C, slow type -0.00723594
RUFY3 RUN and FYVE domain containing 3 -0.0072045
HMGB3 high mobility group box 3 -0.00718665
PRPF4 pre-mRNA processing factor 4 -0.00713675
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00711241
TPM2 tropomyosin 2 (beta) -0.00708295
IGFBP6 insulin-like growth factor binding protein 6 -0.00707331
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00706217
PFN2 profilin 2 -0.0070594
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00705812
GAS1 growth arrest-specific 1 -0.00702593
NNMT nicotinamide N-methyltransferase -0.00702375
S100A4 S100 calcium binding protein A4 -0.00702134
HMGB1 high mobility group box 1 -0.0070125
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.00700582
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00698942
AMACR alpha-methylacyl-CoA racemase -0.00690843
CD9 CD9 molecule -0.00689187
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00689143
FSTL1 follistatin-like 1 -0.00688538
FASN fatty acid synthase -0.00685954
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00682514
TNNT1 troponin T type 1 (skeletal, slow) -0.00681982
IRS2 insulin receptor substrate 2 -0.00679123
KLHL41 kelch-like family member 41 -0.00679092
TMSB15A thymosin beta 15a -0.00673649
ZSCAN18 zinc finger and SCAN domain containing 18 -0.0067338
INSM1 insulinoma-associated 1 -0.00673167
MPC2 mitochondrial pyruvate carrier 2 -0.00670383
NAV2 neuron navigator 2 -0.00669303
CFB complement factor B -0.00668601
AXL AXL receptor tyrosine kinase -0.00667859
TRIO trio Rho guanine nucleotide exchange factor -0.00667178
APMAP adipocyte plasma membrane associated protein -0.00665526
DPYSL2 dihydropyrimidinase-like 2 -0.00665307
EMP3 epithelial membrane protein 3 -0.00662862
SMAD7 SMAD family member 7 -0.00661466
ELN elastin -0.00661422
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00659538
MB myoglobin -0.00659201
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0065512
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00654694
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -0.00654176
ARHGAP22 Rho GTPase activating protein 22 -0.00649494
ATP5MF ATP synthase membrane subunit f -0.00646704
KIAA0930 KIAA0930 -0.00644521
LONP2 lon peptidase 2, peroxisomal -0.00641154
TFPI2 tissue factor pathway inhibitor 2 -0.0064106
EFHD1 EF-hand domain family, member D1 -0.00640682
GREM1 gremlin 1, DAN family BMP antagonist -0.00639149
HPGDS hematopoietic prostaglandin D synthase -0.00636247
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00635685
TTN titin -0.0063127
CP ceruloplasmin (ferroxidase) -0.00626436
PDGFRL platelet-derived growth factor receptor-like -0.00626347
RTN2 reticulon 2 -0.00623478
COMP cartilage oligomeric matrix protein -0.0062347
EML3 echinoderm microtubule associated protein like 3 -0.00620095
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00620028
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -0.0061932
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00619219
DCT dopachrome tautomerase -0.00618822
NECTIN3 nectin cell adhesion molecule 3 -0.00614581
OLFML2A olfactomedin-like 2A -0.00613337
CUX2 cut-like homeobox 2 -0.00610582
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.00610477
ELOVL5 ELOVL fatty acid elongase 5 -0.00607731
ZNF22 zinc finger protein 22 -0.00606403
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00605337
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00605044
ST18 suppression of tumorigenicity 18, zinc finger -0.00604725
CLGN calmegin -0.00604202
IGFBP4 insulin-like growth factor binding protein 4 -0.0060259
LIMCH1 LIM and calponin homology domains 1 -0.00602547
PLXND1 plexin D1 -0.00600581
FMO3 flavin containing monooxygenase 3 -0.0059874
ASS1 argininosuccinate synthase 1 -0.00597173
CKM creatine kinase, muscle -0.00596022
PSD3 pleckstrin and Sec7 domain containing 3 -0.00595603
MZB1 marginal zone B and B1 cell-specific protein -0.0059422
LEPR leptin receptor -0.00593861
TSPO translocator protein (18kDa) -0.00593197
KIF5B kinesin family member 5B -0.00590826
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00590104
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -0.00588969
SLC16A6 solute carrier family 16, member 6 -0.00588901
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00588087
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 -0.00587527
SLC38A4 solute carrier family 38, member 4 -0.00583589
AKR1C1 aldo-keto reductase family 1, member C1 -0.00581039
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.00580659
RAPSN receptor-associated protein of the synapse -0.0058063
ZNF586 zinc finger protein 586 -0.00580578
TTC39A tetratricopeptide repeat domain 39A -0.00580074
VAV3 vav 3 guanine nucleotide exchange factor -0.00579822
SIGLEC15 sialic acid binding Ig-like lectin 15 -0.00579411
TNNT3 troponin T type 3 (skeletal, fast) -0.00579104
PON1 paraoxonase 1 -0.00578291
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00576857
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00576802
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.00575667
PFKM phosphofructokinase, muscle -0.0057277
NDRG2 NDRG family member 2 -0.00571635
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00568722
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00565535
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00565351
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -0.00564783
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -0.00563423
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 -0.0056216
RBX1 ring-box 1, E3 ubiquitin protein ligase -0.00560971
HMG20B high mobility group 20B -0.00560518
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00559875
GLA galactosidase, alpha -0.0055982
AHNAK AHNAK nucleoprotein -0.00557755
EHD2 EH-domain containing 2 -0.00555496
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00554728
RND3 Rho family GTPase 3 -0.00553795
ECI2 enoyl-CoA delta isomerase 2 -0.0055317
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) -0.00553131
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00552027
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00550395
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00549331
ASPN asporin -0.00547419
PMEL premelanosome protein -0.00547245
LECT2 leukocyte cell-derived chemotaxin 2 -0.00544597
ARHGAP29 Rho GTPase activating protein 29 -0.0054433
MACROD1 MACRO domain containing 1 -0.00542074
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00541184
ESR1 estrogen receptor 1 -0.00539755
PCLAF PCNA clamp associated factor -0.00539324
CAPG capping protein (actin filament), gelsolin-like -0.00539128
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00538649
CRABP2 cellular retinoic acid binding protein 2 -0.00537895
TOB1 transducer of ERBB2, 1 -0.00537466
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00536599
FKBP11 FK506 binding protein 11, 19 kDa -0.00535808
CLDN3 claudin 3 -0.00535196
PDHX pyruvate dehydrogenase complex, component X -0.00535094
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00533381
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00532473
PLEC plectin -0.00531702
PID1 phosphotyrosine interaction domain containing 1 -0.00531194
TNNI2 troponin I type 2 (skeletal, fast) -0.00530981
MAGED1 melanoma antigen family D1 -0.00530201
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 -0.00529739
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00527519
EFNB2 ephrin-B2 -0.00527
TRAPPC6A trafficking protein particle complex 6A -0.00526878
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00526348
TSPAN12 tetraspanin 12 -0.00524373
MYOM2 myomesin 2 -0.00524216
MFSD10 major facilitator superfamily domain containing 10 -0.00524014
CCND1 cyclin D1 -0.00523229
MT1E metallothionein 1E -0.00523171
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide -0.00522857
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -0.00522213
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00521
LPXN leupaxin -0.00520902
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00520887
PTN pleiotrophin -0.00520367
EHF ets homologous factor -0.0051914
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) -0.005187
TMEM176B transmembrane protein 176B -0.00518522
COL6A2 collagen, type VI, alpha 2 -0.0051679
NOTCH2 notch 2 -0.00516586
HELLS helicase, lymphoid-specific -0.00514875
TAPBP TAP binding protein (tapasin) -0.00514639
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00514043
DUSP5 dual specificity phosphatase 5 -0.00513866
NOTCH1 notch 1 -0.00511367
ANGPTL2 angiopoietin-like 2 -0.00508291
TOX3 TOX high mobility group box family member 3 -0.00508196
C6 complement component 6 -0.00507621
EPHB3 EPH receptor B3 -0.00507214
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00506973
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00506006
PHGDH phosphoglycerate dehydrogenase -0.00504803
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00504332
IRX5 iroquois homeobox 5 -0.00501979
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00501672