MNK1 Gene Set

Dataset Kinase Library Serine Threonine Kinome Atlas
Category proteomics
Type kinase
Description MAP kinase interacting serine/threonine kinase 1|This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 8569)
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Genes

100 substrates of the kinase MNK1 from the Kinase Library Serine Threonine Kinome Atlas dataset.

Symbol Name Standardized Value
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
KIF2C kinesin family member 2C
KAT5 K(lysine) acetyltransferase 5
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ATF1 activating transcription factor 1
TRA2A transformer 2 alpha homolog (Drosophila)
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
IRS1 insulin receptor substrate 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
SCAF1 SR-related CTD-associated factor 1
PLXNB1 plexin B1
LARP1 La ribonucleoprotein domain family, member 1
LEMD2 LEM domain containing 2
UBE2O ubiquitin-conjugating enzyme E2O
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
RBM15B RNA binding motif protein 15B
NOLC1 nucleolar and coiled-body phosphoprotein 1
OSBPL10 oxysterol binding protein-like 10
SETD2 SET domain containing 2
PRDM2 PR domain containing 2, with ZNF domain
SPN sialophorin
CREB1 cAMP responsive element binding protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
IL2RA interleukin 2 receptor, alpha
SSTR5 somatostatin receptor 5
KMT2A lysine (K)-specific methyltransferase 2A
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
TACSTD2 tumor-associated calcium signal transducer 2
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
RASAL2 RAS protein activator like 2
MRVI1 murine retrovirus integration site 1 homolog
CASKIN2 CASK interacting protein 2
FRMD4B FERM domain containing 4B
MTF2 metal response element binding transcription factor 2
LTBP1 latent transforming growth factor beta binding protein 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
HEXIM1 hexamethylene bis-acetamide inducible 1
ZBTB44 zinc finger and BTB domain containing 44
PPP1R10 protein phosphatase 1, regulatory subunit 10
TP53RK TP53 regulating kinase
PRICKLE3 prickle homolog 3 (Drosophila)
FIGNL1 fidgetin-like 1
TOR4A torsin family 4, member A
MYO7B myosin VIIB
SOX9 SRY (sex determining region Y)-box 9
SRSF2 serine/arginine-rich splicing factor 2
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
FHOD1 formin homology 2 domain containing 1
ANKRD33B ankyrin repeat domain 33B
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
DUOX1 dual oxidase 1
CASC5 cancer susceptibility candidate 5
TP53BP1 tumor protein p53 binding protein 1
GRK7 G protein-coupled receptor kinase 7
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
MAP3K11 mitogen-activated protein kinase kinase kinase 11
RARG retinoic acid receptor, gamma
ATRX alpha thalassemia/mental retardation syndrome X-linked
PHF2 PHD finger protein 2
AEBP2 AE binding protein 2
GPATCH2 G patch domain containing 2
SYT6 synaptotagmin VI
CYTH2 cytohesin 2
DDA1 DET1 and DDB1 associated 1
PYGO2 pygopus family PHD finger 2
DOCK5 dedicator of cytokinesis 5
PPHLN1 periphilin 1
CDCA2 cell division cycle associated 2
INF2 inverted formin, FH2 and WH2 domain containing
CHERP calcium homeostasis endoplasmic reticulum protein
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
NOP56 NOP56 ribonucleoprotein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
LIMK2 LIM domain kinase 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
SYTL1 synaptotagmin-like 1
FOXP3 forkhead box P3
CDC25B cell division cycle 25B
CDC25A cell division cycle 25A
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
TTF1 transcription termination factor, RNA polymerase I
SF1 splicing factor 1
INCENP inner centromere protein antigens 135/155kDa
LOC113230 uncharacterized protein LOC113230
RNF111 ring finger protein 111
NOP2 NOP2 nucleolar protein
APC adenomatous polyposis coli
SRRM2 serine/arginine repetitive matrix 2
KCNK9 potassium channel, two pore domain subfamily K, member 9
MARCKS myristoylated alanine-rich protein kinase C substrate
PITPNB phosphatidylinositol transfer protein, beta
CLK3 CDC-like kinase 3
PRPF4B pre-mRNA processing factor 4B
BAG6 BCL2-associated athanogene 6
KCNK12 potassium channel, two pore domain subfamily K, member 12