MOCOS Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description molybdenum cofactor sulfurase|MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH; MIM 607633) and aldehyde oxidase (AOX1; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 [PubMed 11302742]).[supplied by OMIM, Feb 2010] (NCBI Entrez Gene Database, 55034)
External Link https://ncbi.nlm.nih.gov/gene/55034
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Genes

499 genes differentially expressed following the MOCOS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RHOB ras homolog family member B 0.0113358
CNPY3 canopy FGF signaling regulator 3 0.0111627
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0111585
ANXA3 annexin A3 0.011045
PLK2 polo-like kinase 2 0.0101968
TFPI2 tissue factor pathway inhibitor 2 0.00997536
NUSAP1 nucleolar and spindle associated protein 1 0.00976182
MAGEA3 melanoma antigen family A3 0.0097266
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00938102
GLUL glutamate-ammonia ligase 0.00936484
KRT7 keratin 7, type II 0.00912916
YBX3 Y box binding protein 3 0.00850497
KRT8 keratin 8, type II 0.00835568
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00825549
IRS2 insulin receptor substrate 2 0.00825218
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00825199
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00820912
TXNDC9 thioredoxin domain containing 9 0.0080815
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00780951
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.007766
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.007635
PXDN peroxidasin 0.00762267
ACKR3 atypical chemokine receptor 3 0.0076011
VAMP8 vesicle-associated membrane protein 8 0.00759901
SIK1 salt-inducible kinase 1 0.00758814
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00744332
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.00738815
CLDN1 claudin 1 0.00731759
FGL2 fibrinogen-like 2 0.00719321
SHTN1 shootin 1 0.00717547
RRM2 ribonucleotide reductase M2 0.00712237
ISG15 ISG15 ubiquitin-like modifier 0.00708292
KRT18 keratin 18, type I 0.00701501
CCND2 cyclin D2 0.00697952
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.00691095
STC1 stanniocalcin 1 0.00681932
FUCA1 fucosidase, alpha-L- 1, tissue 0.00677413
ARID1A AT rich interactive domain 1A (SWI-like) 0.00676125
MMP10 matrix metallopeptidase 10 0.00675265
DEFB1 defensin, beta 1 0.00674802
STOM stomatin 0.00673632
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00671635
SGK1 serum/glucocorticoid regulated kinase 1 0.00666016
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00662373
GPX3 glutathione peroxidase 3 0.00659776
WFDC2 WAP four-disulfide core domain 2 0.0065912
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00652594
CAPN1 calpain 1, (mu/I) large subunit 0.00650413
TLR4 toll-like receptor 4 0.00648211
SNX10 sorting nexin 10 0.00645376
SEPP1 selenoprotein P, plasma, 1 0.00639743
PLAAT3 phospholipase A and acyltransferase 3 0.00639727
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00637633
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00636915
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00636115
RREB1 ras responsive element binding protein 1 0.00628838
GPX1 glutathione peroxidase 1 0.006278
FPR3 formyl peptide receptor 3 0.00625267
CD163 CD163 molecule 0.00625
CUX1 cut-like homeobox 1 0.00623749
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.00622008
FNDC3B fibronectin type III domain containing 3B 0.00621611
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00617956
RNF167 ring finger protein 167 0.00617813
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00615806
STIP1 stress-induced phosphoprotein 1 0.00610198
GPNMB glycoprotein (transmembrane) nmb 0.00603626
S100A14 S100 calcium binding protein A14 0.00602926
PCLAF PCNA clamp associated factor 0.00602596
TNNT1 troponin T type 1 (skeletal, slow) 0.00600932
UBE2H ubiquitin-conjugating enzyme E2H 0.00599064
EXOSC4 exosome component 4 0.00598
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.00597648
COPS7A COP9 signalosome subunit 7A 0.00593134
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.00593121
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00591147
GNAS GNAS complex locus 0.00591117
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00587107
UGCG UDP-glucose ceramide glucosyltransferase 0.00586534
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00585226
IRAK1 interleukin-1 receptor-associated kinase 1 0.00584281
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.00581973
MT1E metallothionein 1E 0.00581963
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00581462
KLF6 Kruppel-like factor 6 0.00579315
INHBB inhibin, beta B 0.00578606
AMOTL2 angiomotin like 2 0.00578538
TSPAN1 tetraspanin 1 0.00577004
NXN nucleoredoxin 0.00575989
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 0.00572311
FBXO2 F-box protein 2 0.00572092
ZNHIT1 zinc finger, HIT-type containing 1 0.0056952
TGM2 transglutaminase 2 0.00569419
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.0056923
FN1 fibronectin 1 0.00567127
RBM47 RNA binding motif protein 47 0.00566845
TACSTD2 tumor-associated calcium signal transducer 2 0.00566611
ALOX5 arachidonate 5-lipoxygenase 0.00560269
GABARAPL1 GABA(A) receptor-associated protein like 1 0.00555298
KLK11 kallikrein-related peptidase 11 0.0055378
SH3BP4 SH3-domain binding protein 4 0.00552419
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00549841
PRDX2 peroxiredoxin 2 0.00547899
PXDC1 PX domain containing 1 0.0054715
RETREG2 reticulophagy regulator family member 2 0.00543317
MMP3 matrix metallopeptidase 3 0.00541631
DUSP10 dual specificity phosphatase 10 0.00540506
CP ceruloplasmin (ferroxidase) 0.00540462
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.0054032
DOCK4 dedicator of cytokinesis 4 0.00537901
HSPA1A heat shock 70kDa protein 1A 0.0053778
PCNA proliferating cell nuclear antigen 0.00536523
ZWINT ZW10 interacting kinetochore protein 0.0053403
NUDC nudC nuclear distribution protein 0.00533325
RND3 Rho family GTPase 3 0.00532865
ACOT9 acyl-CoA thioesterase 9 0.0053193
UBAP2L ubiquitin associated protein 2-like 0.0053159
EGR1 early growth response 1 0.00531543
EPHB2 EPH receptor B2 0.00531388
C10ORF10 chromosome 10 open reading frame 10 0.00526334
MSMB microseminoprotein, beta- 0.00525338
MITF microphthalmia-associated transcription factor 0.00523129
LY6E lymphocyte antigen 6 complex, locus E 0.00520097
CTBP2 C-terminal binding protein 2 0.00517699
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.00517517
ZNF638 zinc finger protein 638 0.00516923
CST1 cystatin SN 0.00516378
KCTD14 potassium channel tetramerization domain containing 14 0.00513931
TMEM176B transmembrane protein 176B 0.00511842
TRIP6 thyroid hormone receptor interactor 6 0.00511628
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.00511594
EIF5B eukaryotic translation initiation factor 5B 0.00508644
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00508415
C6 complement component 6 0.00504956
NUP58 nucleoporin 58 0.00504659
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00502466
SPINT1 serine peptidase inhibitor, Kunitz type 1 0.00500396
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00499568
TGFBI transforming growth factor, beta-induced, 68kDa 0.00499401
ABHD2 abhydrolase domain containing 2 0.00499345
C2 complement component 2 0.00498697
FRS2 fibroblast growth factor receptor substrate 2 0.00497673
KIAA0040 KIAA0040 0.00495467
PRSS8 protease, serine, 8 0.00495323
COL4A5 collagen, type IV, alpha 5 0.00493387
PFKM phosphofructokinase, muscle 0.00492786
RTN2 reticulon 2 0.00492504
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00492428
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 0.00492248
PON2 paraoxonase 2 0.00491526
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 0.00490107
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00489857
DDIT3 DNA-damage-inducible transcript 3 0.00489829
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00489497
XIC X chromosome inactivation center 0.00489289
BCAP31 B-cell receptor-associated protein 31 0.00488432
CCR2 chemokine (C-C motif) receptor 2 0.00487307
IGFBP5 insulin-like growth factor binding protein 5 0.00486199
CCR1 chemokine (C-C motif) receptor 1 0.00483792
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.00480531
SDC2 syndecan 2 0.00479387
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.00479356
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.00478246
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.0047788
TLN1 talin 1 0.0047783
GDI1 GDP dissociation inhibitor 1 0.00477571
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.0047523
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.0047522
HSPH1 heat shock 105kDa/110kDa protein 1 0.00475183
SMAD3 SMAD family member 3 0.00472972
ODC1 ornithine decarboxylase 1 0.0047212
KRT19 keratin 19, type I 0.00471608
ZFAND5 zinc finger, AN1-type domain 5 0.00471481
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.00470944
CISH cytokine inducible SH2-containing protein 0.00470218
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.0046932
TMBIM1 transmembrane BAX inhibitor motif containing 1 0.00469141
C1QB complement component 1, q subcomponent, B chain 0.00468452
HDLBP high density lipoprotein binding protein 0.00467754
SALL1 spalt-like transcription factor 1 0.00466993
SOX4 SRY (sex determining region Y)-box 4 0.00466413
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 0.00465801
CST4 cystatin S 0.00465725
EFNA1 ephrin-A1 0.00464717
RBPMS RNA binding protein with multiple splicing 0.00464042
MX1 MX dynamin-like GTPase 1 0.00463869
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.00462716
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00461799
F5 coagulation factor V (proaccelerin, labile factor) 0.00461319
TLR2 toll-like receptor 2 0.00460667
TRIB3 tribbles pseudokinase 3 0.0046064
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.0046048
SPPL2B signal peptide peptidase like 2B 0.00460063
NEU1 sialidase 1 (lysosomal sialidase) 0.00459614
JUP junction plakoglobin 0.00459328
DPT dermatopontin 0.00458616
CXCL6 chemokine (C-X-C motif) ligand 6 0.00458405
MAP7 microtubule-associated protein 7 0.00457489
LDLR low density lipoprotein receptor 0.00454906
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00454585
CDA cytidine deaminase 0.00453567
GTF2IRD1 GTF2I repeat domain containing 1 0.00453288
KIAA0930 KIAA0930 0.00452496
ESRP1 epithelial splicing regulatory protein 1 0.00451549
AHNAK AHNAK nucleoprotein 0.00451546
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00451264
NBPF10 neuroblastoma breakpoint family, member 10 0.00450277
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0044925
FURIN furin (paired basic amino acid cleaving enzyme) 0.0044895
EIF6 eukaryotic translation initiation factor 6 0.00448547
ADAM10 ADAM metallopeptidase domain 10 0.00448045
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00447575
BAG1 BCL2-associated athanogene 0.00447039
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.00445789
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.00444117
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.00443009
ARF3 ADP-ribosylation factor 3 0.00442279
BAD BCL2-associated agonist of cell death 0.00441991
ATG2A autophagy related 2A 0.00441706
HMOX1 heme oxygenase 1 0.0044101
BAG3 BCL2-associated athanogene 3 0.00440301
DHDDS dehydrodolichyl diphosphate synthase 0.00440087
HSPB8 heat shock 22kDa protein 8 0.00439342
ASXL2 additional sex combs like transcriptional regulator 2 0.00439335
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00438407
EPHA2 EPH receptor A2 0.00437079
GSPT1 G1 to S phase transition 1 0.00436745
AFF1 AF4/FMR2 family, member 1 0.00436455
LYPLA1 lysophospholipase I 0.00436148
SLC12A9 solute carrier family 12, member 9 0.00434749
CXCL9 chemokine (C-X-C motif) ligand 9 0.0043454
SSX1 synovial sarcoma, X breakpoint 1 0.00434199
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00433791
NNMT nicotinamide N-methyltransferase 0.00433452
CFH complement factor H 0.00432976
PLSCR3 phospholipid scramblase 3 0.00432685
KLK10 kallikrein-related peptidase 10 0.00432004
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00431665
C4BPA complement component 4 binding protein, alpha 0.00431654
PUM1 pumilio RNA-binding family member 1 0.00430953
ERBB3 erb-b2 receptor tyrosine kinase 3 0.00430594
IRS1 insulin receptor substrate 1 0.00430362
GOLM1 golgi membrane protein 1 0.00429968
PON3 paraoxonase 3 0.0042813
GRB7 growth factor receptor-bound protein 7 0.00428062
FOSL2 FOS-like antigen 2 0.00427578
BIK BCL2-interacting killer (apoptosis-inducing) 0.00426968
RPL10 ribosomal protein L10 0.00426886
MMP8 matrix metallopeptidase 8 0.00426473

decreased expression

Symbol Name Standardized Value
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0146203
ITM2A integral membrane protein 2A -0.0131643
PITX3 paired-like homeodomain 3 -0.0131013
HOPX HOP homeobox -0.0129181
KIF2C kinesin family member 2C -0.0126268
PRR7 proline rich 7 (synaptic) -0.0113337
CD200 CD200 molecule -0.0109557
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0105915
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0103649
CRYBG1 crystallin beta-gamma domain containing 1 -0.00992606
SRPX sushi-repeat containing protein, X-linked -0.00991236
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -0.00938319
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00919492
HEPH hephaestin -0.00900461
CYCS cytochrome c, somatic -0.00898085
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00881157
NT5E 5'-nucleotidase, ecto (CD73) -0.00859108
FAM162A family with sequence similarity 162, member A -0.00858688
PRKCA protein kinase C, alpha -0.0083156
ADIRF adipogenesis regulatory factor -0.00822443
ZW10 zw10 kinetochore protein -0.00821887
NRN1 neuritin 1 -0.00817624
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00816867
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00813251
CD3D CD3d molecule, delta (CD3-TCR complex) -0.00799808
COL6A3 collagen, type VI, alpha 3 -0.00795782
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00792212
DLK1 delta-like 1 homolog (Drosophila) -0.00789305
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00784224
MEF2C myocyte enhancer factor 2C -0.00777502
MATN2 matrilin 2 -0.00775691
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00768424
TGFBR3 transforming growth factor, beta receptor III -0.00767532
WIF1 WNT inhibitory factor 1 -0.00766715
PMP22 peripheral myelin protein 22 -0.0076278
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00759844
TKTL1 transketolase-like 1 -0.00759784
GPM6B glycoprotein M6B -0.00755783
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.00752507
CD69 CD69 molecule -0.0074696
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00745515
CCR7 chemokine (C-C motif) receptor 7 -0.00737972
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -0.00736734
CLDN8 claudin 8 -0.00734092
TSPAN7 tetraspanin 7 -0.0072415
ERAP2 endoplasmic reticulum aminopeptidase 2 -0.00722692
CHRDL1 chordin-like 1 -0.00718881
MEIS2 Meis homeobox 2 -0.0071665
RGS10 regulator of G-protein signaling 10 -0.00711003
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0071036
KRT14 keratin 14, type I -0.00710014
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.0070621
WDR61 WD repeat domain 61 -0.00705098
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00703855
IL2RG interleukin 2 receptor, gamma -0.00703563
BCL2A1 BCL2-related protein A1 -0.00702462
LXN latexin -0.00701685
SFRP4 secreted frizzled-related protein 4 -0.00697673
KRT20 keratin 20, type I -0.00696063
FAR2 fatty acyl CoA reductase 2 -0.00694956
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00692258
S100A10 S100 calcium binding protein A10 -0.00684295
MEN1 multiple endocrine neoplasia I -0.00682694
PRSS3 protease, serine, 3 -0.00677123
CDC20 cell division cycle 20 -0.00671758
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00669476
STK10 serine/threonine kinase 10 -0.00667212
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00663756
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.00663516
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00659746
PASK PAS domain containing serine/threonine kinase -0.00645353
DGKZ diacylglycerol kinase, zeta -0.00642265
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00641616
AKR1C3 aldo-keto reductase family 1, member C3 -0.00641323
PRSS21 protease, serine, 21 (testisin) -0.00640383
CA4 carbonic anhydrase IV -0.00639047
COCH cochlin -0.0063812
CHEK1 checkpoint kinase 1 -0.00637979
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.0063451
MGP matrix Gla protein -0.00630899
NAP1L3 nucleosome assembly protein 1-like 3 -0.00629265
CSTA cystatin A (stefin A) -0.00626884
SI sucrase-isomaltase (alpha-glucosidase) -0.00623459
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00620333
PLS3 plastin 3 -0.00619735
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00607474
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00606977
ABHD4 abhydrolase domain containing 4 -0.00603733
GMFG glia maturation factor, gamma -0.00603122
PDZRN3 PDZ domain containing ring finger 3 -0.00602217
TSPAN13 tetraspanin 13 -0.00601462
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00600783
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00599555
RPL36 ribosomal protein L36 -0.00598063
S100A8 S100 calcium binding protein A8 -0.00597679
DHRS11 dehydrogenase/reductase (SDR family) member 11 -0.00596905
MALL mal, T-cell differentiation protein-like -0.00594059
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -0.00593431
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.00592749
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00590168
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00584596
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.00583368
OGN osteoglycin -0.00583366
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.00582699
SNAP25 synaptosomal-associated protein, 25kDa -0.00580843
CCNF cyclin F -0.00580326
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00580132
RGS4 regulator of G-protein signaling 4 -0.00579459
CRABP1 cellular retinoic acid binding protein 1 -0.00577384
MYBPC1 myosin binding protein C, slow type -0.00576819
DUSP2 dual specificity phosphatase 2 -0.00575675
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 -0.00574645
TYRP1 tyrosinase-related protein 1 -0.0057454
TPM2 tropomyosin 2 (beta) -0.0057371
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00573605
TMEM38B transmembrane protein 38B -0.00572727
TARP TCR gamma alternate reading frame protein -0.00569594
JAM2 junctional adhesion molecule 2 -0.00566697
PCOLCE procollagen C-endopeptidase enhancer -0.00564863
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -0.00558639
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.0055835
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -0.00557395
NDRG1 N-myc downstream regulated 1 -0.00557064
ARHGAP15 Rho GTPase activating protein 15 -0.00554907
NDP Norrie disease (pseudoglioma) -0.00552886
FABP1 fatty acid binding protein 1, liver -0.00549603
RCAN2 regulator of calcineurin 2 -0.00547588
CLIC5 chloride intracellular channel 5 -0.00546354
DOCK10 dedicator of cytokinesis 10 -0.00546339
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00545986
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.00542696
PNMA1 paraneoplastic Ma antigen 1 -0.0054244
MPC2 mitochondrial pyruvate carrier 2 -0.00541871
CCNB2 cyclin B2 -0.00541778
VEGFA vascular endothelial growth factor A -0.0053705
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00536995
C9ORF40 chromosome 9 open reading frame 40 -0.0053485
XYLT1 xylosyltransferase I -0.00533694
BTNL8 butyrophilin-like 8 -0.0053321
PRAME preferentially expressed antigen in melanoma -0.00533065
OPN3 opsin 3 -0.00532421
NFASC neurofascin -0.0053223
S100A7 S100 calcium binding protein A7 -0.0053202
TOX thymocyte selection-associated high mobility group box -0.00531648
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.00530617
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.00530191
MEP1A meprin A, alpha (PABA peptide hydrolase) -0.00530043
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -0.0052999
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00528598
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.00528257
RFTN1 raftlin, lipid raft linker 1 -0.00527442
SRGN serglycin -0.00527211
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -0.00526553
GCH1 GTP cyclohydrolase 1 -0.00524885
SCML2 sex comb on midleg-like 2 (Drosophila) -0.00524685
NRGN neurogranin (protein kinase C substrate, RC3) -0.0052238
GLTP glycolipid transfer protein -0.00520332
CCNI cyclin I -0.00519931
TMEM45A transmembrane protein 45A -0.00518528
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -0.00518432
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00517895
PLP1 proteolipid protein 1 -0.00517701
JAM3 junctional adhesion molecule 3 -0.0051769
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00517427
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00516915
DAD1 defender against cell death 1 -0.00516558
HOXA10 homeobox A10 -0.00515039
MARCKSL1 MARCKS-like 1 -0.0051375
AK4 adenylate kinase 4 -0.00512849
GRAMD2B GRAM domain containing 2B -0.00512365
LYZ lysozyme -0.00511545
BAALC brain and acute leukemia, cytoplasmic -0.00511272
SCN3A sodium channel, voltage gated, type III alpha subunit -0.00510948
THYN1 thymocyte nuclear protein 1 -0.00510237
RCAN1 regulator of calcineurin 1 -0.00510084
CERK ceramide kinase -0.00510046
SCRG1 stimulator of chondrogenesis 1 -0.00510021
PAQR3 progestin and adipoQ receptor family member III -0.00508584
CHKB choline kinase beta -0.00508536
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00507078
GPM6A glycoprotein M6A -0.00507045
VIM vimentin -0.00506678
CCL5 chemokine (C-C motif) ligand 5 -0.0050605
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.00505161
AKAP7 A kinase (PRKA) anchor protein 7 -0.00504573
ARNTL aryl hydrocarbon receptor nuclear translocator-like -0.00503754
MOXD1 monooxygenase, DBH-like 1 -0.00503709
GUCA2A guanylate cyclase activator 2A (guanylin) -0.00501092
CAPN15 calpain 15 -0.00501067
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00500511
JADE3 jade family PHD finger 3 -0.00500395
HAT1 histone acetyltransferase 1 -0.00498924
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00498761
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -0.00495715
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00495267
C1ORF115 chromosome 1 open reading frame 115 -0.00492868
FSCN1 fascin actin-bundling protein 1 -0.00492203
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00490399
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00490338
ECI2 enoyl-CoA delta isomerase 2 -0.00490104
SMAD6 SMAD family member 6 -0.0048999
PRRX1 paired related homeobox 1 -0.00489583
PEX12 peroxisomal biogenesis factor 12 -0.00488768
ACP6 acid phosphatase 6, lysophosphatidic -0.00488381
LOX lysyl oxidase -0.00488225
REL v-rel avian reticuloendotheliosis viral oncogene homolog -0.00488162
TUBB2B tubulin, beta 2B class IIb -0.00487971
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.00487958
DCK deoxycytidine kinase -0.00487719
GPX2 glutathione peroxidase 2 -0.00487251
EIF2D eukaryotic translation initiation factor 2D -0.00485462
CYTL1 cytokine-like 1 -0.00484782
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -0.00484629
MAGT1 magnesium transporter 1 -0.00484606
MTMR11 myotubularin related protein 11 -0.00484426
MBIP MAP3K12 binding inhibitory protein 1 -0.00483852
TTC3 tetratricopeptide repeat domain 3 -0.00482799
POSTN periostin, osteoblast specific factor -0.00482741
GPC3 glypican 3 -0.00482587
DSP desmoplakin -0.00482249
SEC23A Sec23 homolog A (S. cerevisiae) -0.00481022
PPAP2A phosphatidic acid phosphatase type 2A -0.00480716
CPT1A carnitine palmitoyltransferase 1A (liver) -0.0048016
SFRP1 secreted frizzled-related protein 1 -0.00480079
PLN phospholamban -0.00479543
ZNF430 zinc finger protein 430 -0.00478448
COL5A2 collagen, type V, alpha 2 -0.00476676
DMD dystrophin -0.00476453
OAZ1 ornithine decarboxylase antizyme 1 -0.00475801
SPIB Spi-B transcription factor (Spi-1/PU.1 related) -0.00475567
ABHD17A abhydrolase domain containing 17A -0.00475467
COLEC12 collectin sub-family member 12 -0.00475352
ZNF91 zinc finger protein 91 -0.00474969
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00473941
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00473615
PRR5L proline rich 5 like -0.00472832
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00471848
MDFIC MyoD family inhibitor domain containing -0.00471339
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.00469722
GGCT gamma-glutamylcyclotransferase -0.00469127
MYO6 myosin VI -0.00467164
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00466728
CD2 CD2 molecule -0.00465951
PDE4B phosphodiesterase 4B, cAMP-specific -0.00465633
CHI3L2 chitinase 3-like 2 -0.00465446
F2R coagulation factor II (thrombin) receptor -0.00461951
CNR1 cannabinoid receptor 1 (brain) -0.00461504
PRKD1 protein kinase D1 -0.00461193
SNX11 sorting nexin 11 -0.00461125
CHMP2B charged multivesicular body protein 2B -0.00461106