MONO-MAC-6 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Human acute monocytic leukemia cell line; established from the peripheral blood of a 64-year-old man with relapsed acute monocytic leukemia (AML FAB M5) in 1985 following myeloid metaplasia. Sister cell line of MONO-MAC-1. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002333)
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Genes

29 genes with high or low copy number in MONO-MAC-6 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
SHISA2 shisa family member 2 2.76305
LNX2 ligand of numb-protein X 2 2.76305
GSX1 GS homeobox 1 2.76305
POMP proteasome maturation protein 2.76305
RNF6 ring finger protein (C3H2C3 type) 6 2.76305
CDK8 cyclin-dependent kinase 8 2.76305
POLR1D polymerase (RNA) I polypeptide D, 16kDa 2.76305
RPL21 ribosomal protein L21 2.76305
PAN3-AS1 PAN3 antisense RNA 1 2.76305
USP12 ubiquitin specific peptidase 12 2.76305
RASL11A RAS-like, family 11, member A 2.76305
FLT3 fms-related tyrosine kinase 3 2.76305
MTIF3 mitochondrial translational initiation factor 3 2.76305
GPR12 G protein-coupled receptor 12 2.76305
GTF3A general transcription factor IIIA 2.76305
SNORD102 small nucleolar RNA, C/D box 102 2.76305
SNORA27 small nucleolar RNA, H/ACA box 27 2.64759
CDX2 caudal type homeobox 2 2.64759
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 2.64759
PDX1 pancreatic and duodenal homeobox 1 2.64759
ATP5EP2 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2 2.64759
WASF3 WAS protein family, member 3 2.12225
FLT1 fms-related tyrosine kinase 1 2.12225
PAN3 PAN3 poly(A) specific ribonuclease subunit 2.12225

low copy number

Symbol Name Standardized Value
LINC00290 long intergenic non-protein coding RNA 290 -3.49112
LINC00462 long intergenic non-protein coding RNA 462 -2.99615
CYSLTR2 cysteinyl leukotriene receptor 2 -2.9644
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -2.87269
RB1 retinoblastoma 1 -2.83092