MOS Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description v-mos Moloney murine sarcoma viral oncogene homolog|MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009] (NCBI Entrez Gene Database, 4342)
Similar Terms
Downloads & Tools

Genes

343 genes differentially expressed following the MOS gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RAET1E retinoic acid early transcript 1E 2.22298
TBX15 T-box 15 2.22298
GJB5 gap junction protein, beta 5, 31.1kDa 2.22298
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.22298
SLC15A5 solute carrier family 15, member 5 2.22298
CEP295NL CEP295 N-terminal like 2.22298
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.22298
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.22298
GPR21 G protein-coupled receptor 21 2.22298
CA1 carbonic anhydrase I 2.22298
REN renin 2.22298
UNC45B unc-45 homolog B (C. elegans) 2.22298
CNTNAP4 contactin associated protein-like 4 2.22298
BTLA B and T lymphocyte associated 2.22298
ZNF98 zinc finger protein 98 2.22298
AKAP6 A kinase (PRKA) anchor protein 6 2.22298
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.22298
CFHR3 complement factor H-related 3 2.22298
TMPRSS11F transmembrane protease, serine 11F 2.22298
RASL10A RAS-like, family 10, member A 2.22298
NECAB3 N-terminal EF-hand calcium binding protein 3 2.22298
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) 2.22298
PLIN4 perilipin 4 2.22298
RAX retina and anterior neural fold homeobox 2.22298
PCDHB9 protocadherin beta 9 2.22298
CA3 carbonic anhydrase III 2.22298
SFTPB surfactant protein B 2.22298
TSHZ1 teashirt zinc finger homeobox 1 2.22298
TMC3 transmembrane channel-like 3 2.22298
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 2.22298
SPACA7 sperm acrosome associated 7 2.22298
FAM110A family with sequence similarity 110, member A 2.22298
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 2.22298
MYL7 myosin, light chain 7, regulatory 2.22298
INTS3 integrator complex subunit 3 2.22298
LOC105378220 macrophage receptor MARCO-like 2.22298
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 2.22298
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 2.22298
MUC20 mucin 20, cell surface associated 2.22298
GNRH2 gonadotropin-releasing hormone 2 2.22298
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 2.22298
SNPH syntaphilin 2.22298
DRP2 dystrophin related protein 2 2.22298
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.22298
TDRD9 tudor domain containing 9 2.22298
TMEM72 transmembrane protein 72 2.22298
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.22298
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.22298
COPZ2 coatomer protein complex, subunit zeta 2 2.22298
S100A1 S100 calcium binding protein A1 2.22298
FOXJ1 forkhead box J1 2.22298
KIAA1755 KIAA1755 2.22298
EPCIP exosomal polycystin 1 interacting protein 2.22298
PRRC2C proline-rich coiled-coil 2C 2.22298
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.22298
SIM1 single-minded family bHLH transcription factor 1 2.22298
IGSF22 immunoglobulin superfamily, member 22 2.22298
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 2.22298
TMEM40 transmembrane protein 40 2.22298
FOXC2 forkhead box C2 2.22298
TMEM196 transmembrane protein 196 2.22298
GC group-specific component (vitamin D binding protein) 2.22298
MYL10 myosin, light chain 10, regulatory 2.22298
KHDC1L KH homology domain containing 1-like 2.22298
YPEL4 yippee-like 4 (Drosophila) 2.22298
ALDOB aldolase B, fructose-bisphosphate 2.22298
FAM240C family with sequence similarity 240 member C 2.22298
C17ORF114 chromosome 17 open reading frame 114 2.22298
MDFIC2 MyoD family inhibitor domain containing 2 2.22298
CLEC20A C-type lectin domain containing 20A 2.22298
CPHXL cytoplasmic polyadenylated homeobox like 2.22298
TENT5D terminal nucleotidyltransferase 5D 2.22298
TERB1 telomere repeat binding bouquet formation protein 1 2.22298
CLXN calaxin 2.22298
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 2.22298
VSIR V-set immunoregulatory receptor 2.22298
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 2.22298
GATA5 GATA binding protein 5 2.22298
CNTN6 contactin 6 2.22298
ECI1 enoyl-CoA delta isomerase 1 2.22298
IL4 interleukin 4 2.22298
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.22298
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 2.22298
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.22298
MBD5 methyl-CpG binding domain protein 5 2.22298
ARL5C ADP-ribosylation factor-like 5C 2.22298
RHOXF2 Rhox homeobox family, member 2 2.22298
PCDHA7 protocadherin alpha 7 2.22298
FOXD1 forkhead box D1 2.22298
GRXCR1 glutaredoxin, cysteine rich 1 2.22298
IL27RA interleukin 27 receptor, alpha 2.22298
SCN7A sodium channel, voltage gated, type VII alpha subunit 2.22298
DYNAP dynactin associated protein 2.22298
HNF1A HNF1 homeobox A 2.22298
WNT9B wingless-type MMTV integration site family, member 9B 2.22298
NPIPB7 nuclear pore complex interacting protein family, member B7 2.22298
PNPLA1 patatin-like phospholipase domain containing 1 2.22298
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 2.22298
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.22298
S100P S100 calcium binding protein P 2.22298
CCR8 chemokine (C-C motif) receptor 8 2.22298
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.22298
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.22298
LOC114841035 uncharacterized LOC114841035 2.22298
CLCF1 cardiotrophin-like cytokine factor 1 2.22298
TMEM132E transmembrane protein 132E 2.22298
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.22298
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 2.22298
CD248 CD248 molecule, endosialin 2.22298
PSKH2 protein serine kinase H2 2.22298
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 2.22298
CYS1 cystin 1 2.22298
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.22298
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.22298
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 2.22298
ISL1 ISL LIM homeobox 1 2.22298
IL19 interleukin 19 2.22298
OAZ3 ornithine decarboxylase antizyme 3 2.22298
C2ORF66 chromosome 2 open reading frame 66 2.22298
TSNAXIP1 translin-associated factor X interacting protein 1 2.22298
F10 coagulation factor X 2.22298
DYDC1 DPY30 domain containing 1 2.22298
LRTM2 leucine-rich repeats and transmembrane domains 2 2.22298
CST1 cystatin SN 2.22298
HDAC2 histone deacetylase 2 2.22298
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.22298
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.22298
BTNL8 butyrophilin-like 8 2.22298
C11ORF91 chromosome 11 open reading frame 91 2.22298
NOX3 NADPH oxidase 3 2.22298
MLIP muscular LMNA-interacting protein 2.22298
ZFP92 ZFP92 zinc finger protein 2.22298
RGS4 regulator of G-protein signaling 4 2.22298
HMGB4 high mobility group box 4 2.22298
MYLK3 myosin light chain kinase 3 2.22298
GPR149 G protein-coupled receptor 149 2.22298
ADCY4 adenylate cyclase 4 2.22298
IL21 interleukin 21 2.22298
HPGDS hematopoietic prostaglandin D synthase 2.22298
SKA2 spindle and kinetochore associated complex subunit 2 2.22298
PLA2G5 phospholipase A2, group V 2.22298
EVI2A ecotropic viral integration site 2A 2.22298
GOLGA8T golgin A8 family, member T 2.22298
PLCD4 phospholipase C, delta 4 2.22298
CLEC4A C-type lectin domain family 4, member A 2.22298
ZNF843 zinc finger protein 843 2.22298
SAMD7 sterile alpha motif domain containing 7 2.22298
TBX1 T-box 1 2.22298
ITGA10 integrin, alpha 10 2.22298
ZC3H12D zinc finger CCCH-type containing 12D 2.22298
ANKRD53 ankyrin repeat domain 53 2.22298
SCNN1D sodium channel, non voltage gated 1 delta subunit 2.22298
DEFA6 defensin, alpha 6, Paneth cell-specific 2.22298
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 2.22298
NT5C1B 5'-nucleotidase, cytosolic IB 2.22298
CTSO cathepsin O 2.22298
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.22298
LPO lactoperoxidase 2.22298
OR11G2 olfactory receptor, family 11, subfamily G, member 2 2.22298
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.22298
ICAM5 intercellular adhesion molecule 5, telencephalin 2.22298
SIL1 SIL1 nucleotide exchange factor 2.22298
AOC3 amine oxidase, copper containing 3 2.22298
NUTM2D NUT family member 2D 2.22298
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 2.22298
SH2D3C SH2 domain containing 3C 2.22298
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 2.22298
ALLC allantoicase 2.22298
TEX36 testis expressed 36 2.22298
CLN5 ceroid-lipofuscinosis, neuronal 5 2.22298
SHISA6 shisa family member 6 2.22298
MMP19 matrix metallopeptidase 19 2.22298
PAX4 paired box 4 2.22298
GREM1 gremlin 1, DAN family BMP antagonist 2.22298
SDSL serine dehydratase-like 2.22298
ASCL3 achaete-scute family bHLH transcription factor 3 2.22298
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.22298
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.22298
SH2D3A SH2 domain containing 3A 2.22298
ANKRD30B ankyrin repeat domain 30B 2.22298
RHOC ras homolog family member C 2.22298
TWIST1 twist family bHLH transcription factor 1 2.22298
FEM1C fem-1 homolog c (C. elegans) 2.22298
RFC3 replication factor C (activator 1) 3, 38kDa 2.22298
RNASE9 ribonuclease, RNase A family, 9 (non-active) 2.22298
AKNAD1 AKNA domain containing 1 2.22298
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 2.22298
VAX2 ventral anterior homeobox 2 2.22298
CCL27 chemokine (C-C motif) ligand 27 2.22298
ZNF473 zinc finger protein 473 2.22298
WFDC13 WAP four-disulfide core domain 13 2.22298
TBC1D21 TBC1 domain family, member 21 2.22298
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 2.22298
GALP galanin-like peptide 2.22298
FXYD2 FXYD domain containing ion transport regulator 2 2.22298
FRMD6 FERM domain containing 6 2.22026
MADD MAP-kinase activating death domain 2.22026
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 2.21978
SPHK2 sphingosine kinase 2 2.21641
ADNP activity-dependent neuroprotector homeobox 2.21313
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 2.19748
PC pyruvate carboxylase 2.19393
FAM174B family with sequence similarity 174, member B 2.19147
THAP8 THAP domain containing 8 2.1826
FSD1L fibronectin type III and SPRY domain containing 1-like 2.1723
TRIM4 tripartite motif containing 4 2.16739
PALB2 partner and localizer of BRCA2 2.15384
YIPF6 Yip1 domain family, member 6 2.14912
RFTN1 raftlin, lipid raft linker 1 2.13462
PRTFDC1 phosphoribosyl transferase domain containing 1 2.1267
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 2.1265
MSH3 mutS homolog 3 2.11692
LYSET lysosomal enzyme trafficking factor 2.1141
TM9SF3 transmembrane 9 superfamily member 3 2.10858
NOVA1 neuro-oncological ventral antigen 1 2.10187
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.10187
PXN paxillin 2.09823
ADAM9 ADAM metallopeptidase domain 9 2.09823
FBLN1 fibulin 1 2.09591
TPBG trophoblast glycoprotein 2.09176
CEP85L centrosomal protein 85kDa-like 2.07218
MIB2 mindbomb E3 ubiquitin protein ligase 2 2.06383
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 2.05602
ZNF322 zinc finger protein 322 2.05298
ADIPOR2 adiponectin receptor 2 2.05051
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 2.04488
SAAL1 serum amyloid A-like 1 2.04488
TULP4 tubby like protein 4 2.0425
GLCE glucuronic acid epimerase 2.01729
HNF4G hepatocyte nuclear factor 4, gamma 2.01168
TNK2 tyrosine kinase, non-receptor, 2 2.00532
NRG3 neuregulin 3 2.0031

decreased expression

Symbol Name Standardized Value
INPP5J inositol polyphosphate-5-phosphatase J -2.22298
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -2.22298
RAPSN receptor-associated protein of the synapse -2.22298
CORO1B coronin, actin binding protein, 1B -2.22298
OLFM1 olfactomedin 1 -2.22298
HSPB11 heat shock protein family B (small), member 11 -2.22298
RNF167 ring finger protein 167 -2.22298
ZBTB40 zinc finger and BTB domain containing 40 -2.22298
ERN2 endoplasmic reticulum to nucleus signaling 2 -2.22298
PKD1L1 polycystic kidney disease 1 like 1 -2.22298
ARSI arylsulfatase family, member I -2.22298
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -2.22298
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.22298
SGMS2 sphingomyelin synthase 2 -2.22298
ZNF619 zinc finger protein 619 -2.22298
RHOA ras homolog family member A -2.22298
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.22298
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 -2.22298
DMXL2 Dmx-like 2 -2.22298
STK31 serine/threonine kinase 31 -2.22298
NPIPA2 nuclear pore complex interacting protein family, member A2 -2.22298
TNNI1 troponin I type 1 (skeletal, slow) -2.22298
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) -2.22298
NPPC natriuretic peptide C -2.22298
REC114 REC114 meiotic recombination protein -2.22298
ASIC4 acid sensing (proton gated) ion channel family member 4 -2.22298
LTF lactotransferrin -2.22298
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) -2.22298
PCDHGA9 protocadherin gamma subfamily A, 9 -2.22298
KYAT1 kynurenine aminotransferase 1 -2.22298
METTL26 methyltransferase like 26 -2.22298
SMIM41 small integral membrane protein 41 -2.22298
RAMACL RNA guanine-7 methyltransferase activating subunit like -2.22298
ARID4B AT rich interactive domain 4B (RBP1-like) -2.22298
ACP2 acid phosphatase 2, lysosomal -2.22298
TRIP4 thyroid hormone receptor interactor 4 -2.22298
ZNF597 zinc finger protein 597 -2.22298
POMC proopiomelanocortin -2.22298
GDA guanine deaminase -2.22298
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -2.22298
IRF6 interferon regulatory factor 6 -2.22298
AKR1D1 aldo-keto reductase family 1, member D1 -2.22298
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -2.22298
CHPF2 chondroitin polymerizing factor 2 -2.22298
CRIPTO3 cripto, EGF-CFC family member 3 -2.22298
RASA4 RAS p21 protein activator 4 -2.22298
CAV1 caveolin 1, caveolae protein, 22kDa -2.22298
ECE2 endothelin converting enzyme 2 -2.22298
TTBK2 tau tubulin kinase 2 -2.22298
SMAD2 SMAD family member 2 -2.22298
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 -2.22298
STIP1 stress-induced phosphoprotein 1 -2.22298
PCDHGA8 protocadherin gamma subfamily A, 8 -2.22298
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 -2.22298
FBXO32 F-box protein 32 -2.22298
EMILIN1 elastin microfibril interfacer 1 -2.22298
OPA1 optic atrophy 1 (autosomal dominant) -2.22298
CD200R1 CD200 receptor 1 -2.22298
ANKRD55 ankyrin repeat domain 55 -2.22298
TSLIG3C tRNA splicing ligase complex subunit 3C -2.22298
HNMT histamine N-methyltransferase -2.22298
ERCC6 excision repair cross-complementation group 6 -2.22298
RIBC1 RIB43A domain with coiled-coils 1 -2.22298
CPZ carboxypeptidase Z -2.22298
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -2.22298
ZMYND12 zinc finger, MYND-type containing 12 -2.22298
PRKG2 protein kinase, cGMP-dependent, type II -2.22298
INCENP inner centromere protein antigens 135/155kDa -2.22298
NIFK nucleolar protein interacting with the FHA domain of MKI67 -2.22298
TMEM86B transmembrane protein 86B -2.22298
SNTN sentan, cilia apical structure protein -2.22298
PRNP prion protein -2.22298
FAM216A family with sequence similarity 216, member A -2.22026
FBRSL1 fibrosin-like 1 -2.21978
TBC1D22A TBC1 domain family, member 22A -2.21641
COTL1 coactosin-like F-actin binding protein 1 -2.21641
RNF41 ring finger protein 41, E3 ubiquitin protein ligase -2.20829
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 -2.19748
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B -2.19748
SVBP small vasohibin binding protein -2.19238
DENND2C DENN/MADD domain containing 2C -2.16853
IRF7 interferon regulatory factor 7 -2.15384
ZSCAN12 zinc finger and SCAN domain containing 12 -2.11924
RPGR retinitis pigmentosa GTPase regulator -2.11692
TMEM232 transmembrane protein 232 -2.11692
ZNF780B zinc finger protein 780B -2.11297
TMED5 transmembrane emp24 protein transport domain containing 5 -2.10187
STK11IP serine/threonine kinase 11 interacting protein -2.10038
BST1 bone marrow stromal cell antigen 1 -2.07218
HSPA12B heat shock 70kD protein 12B -2.07218
RARB retinoic acid receptor, beta -2.07218
TSPAN10 tetraspanin 10 -2.07218
HMGA2 high mobility group AT-hook 2 -2.07211
LRRC47 leucine rich repeat containing 47 -2.07107
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -2.07085
CALB1 calbindin 1, 28kDa -2.06778
ABHD6 abhydrolase domain containing 6 -2.06778
FRS3 fibroblast growth factor receptor substrate 3 -2.06778
NXPE3 neurexophilin and PC-esterase domain family, member 3 -2.06778
CALB2 calbindin 2 -2.06778
CREM cAMP responsive element modulator -2.05051
CHEK2 checkpoint kinase 2 -2.05051
WDR45 WD repeat domain 45 -2.0425
INTS6 integrator complex subunit 6 -2.04006
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -2.02586
RGS16 regulator of G-protein signaling 16 -2.02411
FNDC3A fibronectin type III domain containing 3A -2.01774
ATG13 autophagy related 13 -2.01774
TEFM transcription elongation factor, mitochondrial -2.01774
MACF1 microtubule-actin crosslinking factor 1 -2.01257
TMEM59 transmembrane protein 59 -2.00596