MPG Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description N-methylpurine-DNA glycosylase| (NCBI Entrez Gene Database, 4350)
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Genes

313 genes differentially expressed following the MPG gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
RAB44 RAB44, member RAS oncogene family 2.9112
SCN2B sodium channel, voltage gated, type II beta subunit 2.9112
IGFL2 IGF-like family member 2 2.9112
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 2.9112
TXNDC2 thioredoxin domain containing 2 (spermatozoa) 2.9112
ADRB2 adrenoceptor beta 2, surface 2.9112
PDIA2 protein disulfide isomerase family A, member 2 2.9112
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7 2.9112
PDYN prodynorphin 2.9112
PI16 peptidase inhibitor 16 2.9112
NPAP1 nuclear pore associated protein 1 2.9112
LOC390937 Ets2 repressor factor-like 2.9112
ELAVL4 ELAV like neuron-specific RNA binding protein 4 2.9112
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 2.9112
LBHD1 LBH domain containing 1 2.9112
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.9112
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.9112
FOLR1 folate receptor 1 (adult) 2.9112
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.9112
PCDHB6 protocadherin beta 6 2.9112
PCDHB9 protocadherin beta 9 2.9112
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.9112
THRSP thyroid hormone responsive 2.9112
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 2.9112
NCKAP1L NCK-associated protein 1-like 2.9112
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 2.9112
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 2.9112
TBATA thymus, brain and testes associated 2.9112
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 2.9112
ATOH1 atonal homolog 1 (Drosophila) 2.9112
OTUD6A OTU deubiquitinase 6A 2.9112
TRIM74 tripartite motif containing 74 2.9112
CCL5 chemokine (C-C motif) ligand 5 2.9112
ARHGAP36 Rho GTPase activating protein 36 2.9112
XCL1 chemokine (C motif) ligand 1 2.9112
FNDC7 fibronectin type III domain containing 7 2.9112
SLC30A4 solute carrier family 30 (zinc transporter), member 4 2.9112
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.9112
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.9112
SSTR5 somatostatin receptor 5 2.9112
MYO16 myosin XVI 2.9112
CIMIP2C ciliary microtubule inner protein 2C 2.9112
ZAR1 zygote arrest 1 2.9112
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.9112
HBG2 hemoglobin, gamma G 2.9112
CAPN9 calpain 9 2.9112
GPR35 G protein-coupled receptor 35 2.9112
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 2.9112
SPEM1 spermatid maturation 1 2.9112
SLC2A7 solute carrier family 2 (facilitated glucose transporter), member 7 2.9112
CES4A carboxylesterase 4A 2.9112
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 2.9112
H3C14 H3 clustered histone 14 2.9112
EZHIP EZH inhibitory protein 2.9112
GARIN6 golgi associated RAB2 interactor family member 6 2.9112
CFAP206 cilia and flagella associated protein 206 2.9112
PLAAT4 phospholipase A and acyltransferase 4 2.9112
ASDURF ASNSD1 upstream open reading frame 2.9112
H3-5 H3.5 histone 2.9112
STING1 stimulator of interferon response cGAMP interactor 1 2.9112
MYZAP myocardial zonula adherens protein 2.9112
LMNTD1 lamin tail domain containing 1 2.9112
NEURL3 neuralized E3 ubiquitin protein ligase 3 2.9112
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.9112
SH3TC2 SH3 domain and tetratricopeptide repeats 2 2.9112
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 2.9112
LOC124909439 uncharacterized LOC124909439 2.9112
MEOX1 mesenchyme homeobox 1 2.9112
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 2.9112
CCDC13 coiled-coil domain containing 13 2.9112
PCDHB12 protocadherin beta 12 2.9112
LSP1 lymphocyte-specific protein 1 2.9112
TCF23 transcription factor 23 2.9112
PRDM7 PR domain containing 7 2.9112
PRDM6 PR domain containing 6 2.9112
LRRC71 leucine rich repeat containing 71 2.9112
HAL histidine ammonia-lyase 2.9112
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 2.9112
TIMD4 T-cell immunoglobulin and mucin domain containing 4 2.9112
ABHD12 abhydrolase domain containing 12 2.9112
SAA4 serum amyloid A4, constitutive 2.9112
PCDHA6 protocadherin alpha 6 2.9112
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 2.9112
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.9112
DMRT1 doublesex and mab-3 related transcription factor 1 2.9112
LRRC43 leucine rich repeat containing 43 2.9112
FNDC1 fibronectin type III domain containing 1 2.9112
VHLL von Hippel-Lindau tumor suppressor-like 2.9112
PRH2 proline-rich protein HaeIII subfamily 2 2.9112
LRRC32 leucine rich repeat containing 32 2.9112
DAW1 dynein assembly factor with WDR repeat domains 1 2.9112
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 2.9112
LHX5 LIM homeobox 5 2.9112
KRT17 keratin 17, type I 2.9112
OPRK1 opioid receptor, kappa 1 2.9112
CD177 CD177 molecule 2.9112
CYTH4 cytohesin 4 2.9112
NTSR2 neurotensin receptor 2 2.9112
ABHD1 abhydrolase domain containing 1 2.9112
CCL27 chemokine (C-C motif) ligand 27 2.9112
TF transferrin 2.9112
LCT lactase 2.9112
CHI3L2 chitinase 3-like 2 2.9112
KLK12 kallikrein-related peptidase 12 2.9112
C22ORF42 chromosome 22 open reading frame 42 2.9112
NPBWR1 neuropeptides B/W receptor 1 2.9112
SAMD7 sterile alpha motif domain containing 7 2.9112
TBX1 T-box 1 2.9112
SLCO2B1 solute carrier organic anion transporter family, member 2B1 2.9112
SPATA4 spermatogenesis associated 4 2.9112
AICDA activation-induced cytidine deaminase 2.9112
PLET1 placenta expressed transcript 1 2.9112
TDRD15 tudor domain containing 15 2.9112
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 2.9112
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 2.9112
TSLP thymic stromal lymphopoietin 2.9112
DQX1 DEAQ box RNA-dependent ATPase 1 2.9112
MC5R melanocortin 5 receptor 2.9112
GPR142 G protein-coupled receptor 142 2.9112
UBASH3A ubiquitin associated and SH3 domain containing A 2.9112
IL10RA interleukin 10 receptor, alpha 2.9112
C10ORF105 chromosome 10 open reading frame 105 2.9112
FRMPD1 FERM and PDZ domain containing 1 2.9112
CLEC18B C-type lectin domain family 18, member B 2.9112
GCSAML germinal center-associated, signaling and motility-like 2.9112
BPIFC BPI fold containing family C 2.9112
GPR17 G protein-coupled receptor 17 2.9112
OR4M2 olfactory receptor, family 4, subfamily M, member 2 2.9112
NLRP3 NLR family, pyrin domain containing 3 2.9112
NPC1L1 NPC1-like 1 2.9112
ITGA8 integrin, alpha 8 2.9112
CCDC89 coiled-coil domain containing 89 2.9112
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 2.9112
OR2H1 olfactory receptor, family 2, subfamily H, member 1 2.9112
GH1 growth hormone 1 2.9112
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.9112
POTEI POTE ankyrin domain family, member I 2.9112
ADGRF4 adhesion G protein-coupled receptor F4 2.9112
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.9112
APOL6 apolipoprotein L, 6 2.9112
MEPE matrix extracellular phosphoglycoprotein 2.9112
APOL4 apolipoprotein L, 4 2.9112
CHRM1 cholinergic receptor, muscarinic 1 2.9112
EXTL3 exostosin-like glycosyltransferase 3 2.88936
PRPF38A pre-mRNA processing factor 38A 2.73534
ZBTB18 zinc finger and BTB domain containing 18 2.71793
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 2.53764
AR androgen receptor 2.53764
ATP5PD ATP synthase peripheral stalk subunit d 2.53764
KDM1A lysine (K)-specific demethylase 1A 2.53764
TSACC TSSK6 activating co-chaperone 2.53764
OSBP oxysterol binding protein 2.53764
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.48723
MPL MPL proto-oncogene, thrombopoietin receptor 2.46743
MTMR12 myotubularin related protein 12 2.45683
CYB5D2 cytochrome b5 domain containing 2 2.43664
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.41728
PKDCC protein kinase domain containing, cytoplasmic 2.41728
SLC22A10 solute carrier family 22, member 10 2.36028
NDEL1 nudE neurodevelopment protein 1-like 1 2.36028
NOS2 nitric oxide synthase 2, inducible 2.36028
BAG2 BCL2-associated athanogene 2 2.36028
ZFR zinc finger RNA binding protein 2.34845
FBXL14 F-box and leucine-rich repeat protein 14 2.33446
CXCL14 chemokine (C-X-C motif) ligand 14 2.33446
MRC1 mannose receptor, C type 1 2.33446
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 2.32275
CLYBL citrate lyase beta like 2.32101
NARS1 asparaginyl-tRNA synthetase 1 2.28734
OTUD3 OTU deubiquitinase 3 2.28734
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 2.28211
CABLES1 Cdk5 and Abl enzyme substrate 1 2.25485
GPS2 G protein pathway suppressor 2 2.2394
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.21851
EXO5 exonuclease 5 2.20048
COG8 component of oligomeric golgi complex 8 2.20048
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.19354
MYRIP myosin VIIA and Rab interacting protein 2.18853
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1 2.18853
MAPK4 mitogen-activated protein kinase 4 2.16247
RIMOC1 RAB7A interacting MON1-CCZ1 complex subunit 1 2.15845
NOXO1 NADPH oxidase organizer 1 2.14811
KCNRG potassium channel regulator 2.14811
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.14811
CSMD3 CUB and Sushi multiple domains 3 2.14811
AASDH aminoadipate-semialdehyde dehydrogenase 2.14462
DACH1 dachshund family transcription factor 1 2.09401
CHRM2 cholinergic receptor, muscarinic 2 2.09401
ZNF570 zinc finger protein 570 2.08354
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.07649
GSTO1 glutathione S-transferase omega 1 2.06938
DHRS11 dehydrogenase/reductase (SDR family) member 11 2.05585
SERP2 stress-associated endoplasmic reticulum protein family member 2 2.03524
USP51 ubiquitin specific peptidase 51 2.02189
TCAF1 TRPM8 channel-associated factor 1 2.01374
COMMD10 COMM domain containing 10 2.01355

decreased expression

Symbol Name Standardized Value
SCN1A sodium channel, voltage gated, type I alpha subunit -2.9112
ZBTB47 zinc finger and BTB domain containing 47 -2.9112
ZNF284 zinc finger protein 284 -2.9112
COL9A2 collagen, type IX, alpha 2 -2.9112
EID2 EP300 interacting inhibitor of differentiation 2 -2.9112
ZSCAN22 zinc finger and SCAN domain containing 22 -2.9112
NOL4 nucleolar protein 4 -2.9112
MANBAL mannosidase, beta A, lysosomal-like -2.9112
H3C6 H3 clustered histone 6 -2.90562
ZNF415 zinc finger protein 415 -2.8188
DHCR7 7-dehydrocholesterol reductase -2.77789
ZNF443 zinc finger protein 443 -2.68626
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -2.60372
IFT43 intraflagellar transport 43 -2.59459
TMEM9 transmembrane protein 9 -2.59459
CCNA2 cyclin A2 -2.58449
AGBL1 ATP/GTP binding protein-like 1 -2.53764
SPDYE2B speedy/RINGO cell cycle regulator family member E2B -2.53764
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -2.53764
LRRIQ4 leucine-rich repeats and IQ motif containing 4 -2.53764
DEFB134 defensin, beta 134 -2.53764
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2 -2.53764
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 -2.53764
CLCN4 chloride channel, voltage-sensitive 4 -2.53764
PRPF19 pre-mRNA processing factor 19 -2.53764
NMUR1 neuromedin U receptor 1 -2.53764
NR4A3 nuclear receptor subfamily 4, group A, member 3 -2.53764
C1ORF146 chromosome 1 open reading frame 146 -2.53764
NPSR1 neuropeptide S receptor 1 -2.53764
VEGFD vascular endothelial growth factor D -2.53764
GOLGA6L7 golgin A6 family like 7 -2.53764
PCDHGA9 protocadherin gamma subfamily A, 9 -2.53764
PHF11 PHD finger protein 11 -2.53764
POU2F1 POU class 2 homeobox 1 -2.53764
PIWIL3 piwi-like RNA-mediated gene silencing 3 -2.53764
STXBP2 syntaxin binding protein 2 -2.53764
TSGA10IP testis specific, 10 interacting protein -2.53764
ZNF99 zinc finger protein 99 -2.53764
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -2.53764
LURAP1L leucine rich adaptor protein 1-like -2.53764
PKD1L1 polycystic kidney disease 1 like 1 -2.53764
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 -2.53764
CBX8 chromobox homolog 8 -2.53764
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -2.53764
PCDHGB1 protocadherin gamma subfamily B, 1 -2.53764
INSM1 insulinoma-associated 1 -2.53764
ZNF843 zinc finger protein 843 -2.53764
RASA4 RAS p21 protein activator 4 -2.53764
AQP7 aquaporin 7 -2.53764
HSPB2 heat shock 27kDa protein 2 -2.53764
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -2.53764
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) -2.51675
TSLIG1 tRNA splicing ligase complex subunit 1 -2.48166
RUFY1 RUN and FYVE domain containing 1 -2.46434
EXD3 exonuclease 3'-5' domain containing 3 -2.45683
ENO1 enolase 1, (alpha) -2.41728
RAD51B RAD51 paralog B -2.37504
LDHA lactate dehydrogenase A -2.36378
RNF44 ring finger protein 44 -2.36378
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.36378
SLC22A31 solute carrier family 22, member 31 -2.36028
MFAP4 microfibrillar-associated protein 4 -2.36028
PCNA proliferating cell nuclear antigen -2.36028
OVGP1 oviductal glycoprotein 1, 120kDa -2.36028
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -2.36028
MROH6 maestro heat-like repeat family member 6 -2.36028
TNPO1 transportin 1 -2.34407
RPS7 ribosomal protein S7 -2.33622
CAMK2G calcium/calmodulin-dependent protein kinase II gamma -2.33446
CAPN5 calpain 5 -2.33446
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.32101
SFT2D3 SFT2 domain containing 3 -2.31389
POFUT4 protein O-fucosyltransferase 4 -2.29147
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.28734
RABGAP1 RAB GTPase activating protein 1 -2.28734
COL9A1 collagen, type IX, alpha 1 -2.28734
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -2.28728
PGP phosphoglycolate phosphatase -2.2695
GAL3ST1 galactose-3-O-sulfotransferase 1 -2.26799
MSTO1 misato 1, mitochondrial distribution and morphology regulator -2.24688
ACBD3 acyl-CoA binding domain containing 3 -2.24098
ADAM19 ADAM metallopeptidase domain 19 -2.21683
INTS2 integrator complex subunit 2 -2.21111
RAB18 RAB18, member RAS oncogene family -2.20048
THAP11 THAP domain containing 11 -2.19354
IGSF3 immunoglobulin superfamily, member 3 -2.19354
PNMA8C PNMA family member 8C -2.19087
IFITM1 interferon induced transmembrane protein 1 -2.18853
EIF5 eukaryotic translation initiation factor 5 -2.17984
MTURN maturin, neural progenitor differentiation regulator homolog (Xenopus) -2.17646
S100A10 S100 calcium binding protein A10 -2.16247
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma -2.15845
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 -2.14909
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.14811
AMMECR1L AMMECR1-like -2.13874
BZW2 basic leucine zipper and W2 domains 2 -2.13815
TAMM41 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) -2.12277
AHDC1 AT hook, DNA binding motif, containing 1 -2.12058
LRRC37A leucine rich repeat containing 37A -2.10455
NBPF8 neuroblastoma breakpoint family, member 8 -2.09317
SLC35F1 solute carrier family 35, member F1 -2.09317
CTPS2 CTP synthase 2 -2.08275
PUF60 poly-U binding splicing factor 60KDa -2.07893
NEK6 NIMA-related kinase 6 -2.07432
TMEM219 transmembrane protein 219 -2.07293
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 -2.07293
CAPN3 calpain 3, (p94) -2.06938
CNTN2 contactin 2 (axonal) -2.06938
LRRC8E leucine rich repeat containing 8 family, member E -2.06938
SUSD1 sushi domain containing 1 -2.06223
WBP4 WW domain binding protein 4 -2.05543
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -2.04814
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 -2.03524
LHFPL2 lipoma HMGIC fusion partner-like 2 -2.03524
MRPL1 mitochondrial ribosomal protein L1 -2.0321
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.02656
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.0118