MRAP Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description melanocortin 2 receptor accessory protein|This gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2. Alternatively spliced transcript variants have been described. [provided by RefSeq, Dec 2009] (NCBI Entrez Gene Database, 56246)
External Link https://ncbi.nlm.nih.gov/gene/56246
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Genes

499 genes differentially expressed following the MRAP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ADIRF adipogenesis regulatory factor 0.0162567
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.0149086
P3H2 prolyl 3-hydroxylase 2 0.0143868
CDC42 cell division cycle 42 0.013999
CA12 carbonic anhydrase XII 0.0128859
NDRG1 N-myc downstream regulated 1 0.0122917
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.012151
CD9 CD9 molecule 0.0120514
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.011623
VWF von Willebrand factor 0.011618
LIMA1 LIM domain and actin binding 1 0.0115495
FGFR3 fibroblast growth factor receptor 3 0.01147
AGR2 anterior gradient 2 0.0112922
CLU clusterin 0.0112785
PIP prolactin-induced protein 0.0110927
BIRC3 baculoviral IAP repeat containing 3 0.0110647
SOX9 SRY (sex determining region Y)-box 9 0.0110391
S100P S100 calcium binding protein P 0.0109229
GJA1 gap junction protein, alpha 1, 43kDa 0.0109141
DLK1 delta-like 1 homolog (Drosophila) 0.0107935
CSTA cystatin A (stefin A) 0.0107222
IL7R interleukin 7 receptor 0.0105663
KRT13 keratin 13, type I 0.00997697
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00976197
CTSZ cathepsin Z 0.00975831
KAZN kazrin, periplakin interacting protein 0.00963248
TM4SF1 transmembrane 4 L six family member 1 0.00952254
S100A2 S100 calcium binding protein A2 0.00948664
KRT17 keratin 17, type I 0.00948098
CPE carboxypeptidase E 0.0093633
COL1A2 collagen, type I, alpha 2 0.00931303
PLPP3 phospholipid phosphatase 3 0.00929029
MGLL monoglyceride lipase 0.00911623
LIMCH1 LIM and calponin homology domains 1 0.00901888
RIN2 Ras and Rab interactor 2 0.00891673
TARP TCR gamma alternate reading frame protein 0.00885871
KRT5 keratin 5, type II 0.00882791
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00878487
TCTA T-cell leukemia translocation altered 0.00873777
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.0086978
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.00851622
HSPB8 heat shock 22kDa protein 8 0.00850977
KRT14 keratin 14, type I 0.00830299
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.00827921
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00821756
NPTX2 neuronal pentraxin II 0.00819809
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00805969
AUTS2 autism susceptibility candidate 2 0.00805145
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.0079868
MSMB microseminoprotein, beta- 0.00796122
RTN2 reticulon 2 0.0079353
BHLHE41 basic helix-loop-helix family, member e41 0.00789732
FXYD2 FXYD domain containing ion transport regulator 2 0.00789557
TOB1 transducer of ERBB2, 1 0.00788161
TFF1 trefoil factor 1 0.00787444
METTL7A methyltransferase like 7A 0.00784004
AQP3 aquaporin 3 (Gill blood group) 0.00775739
DSG3 desmoglein 3 0.00774668
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.0077147
FST follistatin 0.0076502
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.00760941
TSPAN1 tetraspanin 1 0.00760936
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00758904
ESM1 endothelial cell-specific molecule 1 0.00758142
EDN1 endothelin 1 0.00757085
NR2F1 nuclear receptor subfamily 2, group F, member 1 0.0075657
CARD10 caspase recruitment domain family, member 10 0.00755911
AKR1C3 aldo-keto reductase family 1, member C3 0.00750395
NUSAP1 nucleolar and spindle associated protein 1 0.00748556
PRPF4 pre-mRNA processing factor 4 0.00747392
EZR ezrin 0.00745129
FAM107A family with sequence similarity 107, member A 0.00739749
EMP1 epithelial membrane protein 1 0.00733967
NTS neurotensin 0.00731581
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00729816
TBX3 T-box 3 0.00725517
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.00725208
BASP1 brain abundant, membrane attached signal protein 1 0.007235
SIRT3 sirtuin 3 0.00722087
H1-2 H1.2 linker histone, cluster member 0.00721294
INSR insulin receptor 0.00720436
GLIPR1 GLI pathogenesis-related 1 0.00720352
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00719331
PRUNE2 prune homolog 2 (Drosophila) 0.00713689
FCGBP Fc fragment of IgG binding protein 0.00712375
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00711993
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.00711596
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00708681
MYBPC1 myosin binding protein C, slow type 0.00707257
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0070186
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00700121
SPRR1A small proline-rich protein 1A 0.00699568
CRABP2 cellular retinoic acid binding protein 2 0.00697453
BTG1 B-cell translocation gene 1, anti-proliferative 0.00694989
PMP22 peripheral myelin protein 22 0.00694316
MXRA7 matrix-remodelling associated 7 0.00694064
SNAP25 synaptosomal-associated protein, 25kDa 0.00689516
TMED3 transmembrane emp24 protein transport domain containing 3 0.00689339
RNF19B ring finger protein 19B 0.00689271
FSCN1 fascin actin-bundling protein 1 0.00687997
MGAM maltase-glucoamylase 0.00687473
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.00687004
IGFBP4 insulin-like growth factor binding protein 4 0.00685749
MALL mal, T-cell differentiation protein-like 0.0068385
GUCY2C guanylate cyclase 2C 0.00680768
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.00678746
KRT19 keratin 19, type I 0.00677581
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00676117
TMEM204 transmembrane protein 204 0.00675126
PLVAP plasmalemma vesicle associated protein 0.00670713
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00664211
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00663593
IGFBP6 insulin-like growth factor binding protein 6 0.00663173
DIXDC1 DIX domain containing 1 0.0066269
KRT16 keratin 16, type I 0.0066197
PTN pleiotrophin 0.00660799
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00657926
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.00656594
SNX7 sorting nexin 7 0.00653517
CRYAB crystallin, alpha B 0.00651353
MB myoglobin 0.00646192
ACAT2 acetyl-CoA acetyltransferase 2 0.00645436
BMP2 bone morphogenetic protein 2 0.00644759
PUDP pseudouridine 5'-phosphatase 0.0064371
GPRC5C G protein-coupled receptor, class C, group 5, member C 0.00642289
PITX1 paired-like homeodomain 1 0.00642121
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00641361
TYMP thymidine phosphorylase 0.00639317
KRT15 keratin 15, type I 0.0063925
NANS N-acetylneuraminic acid synthase 0.00638578
GPC3 glypican 3 0.00637053
MMP9 matrix metallopeptidase 9 0.00635266
ZNF395 zinc finger protein 395 0.00634076
S100A4 S100 calcium binding protein A4 0.00633211
PI3 peptidase inhibitor 3, skin-derived 0.00632561
ELN elastin 0.00628455
EREG epiregulin 0.00627217
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.00626264
RASIP1 Ras interacting protein 1 0.00625815
MCTP1 multiple C2 domains, transmembrane 1 0.00625664
COL2A1 collagen, type II, alpha 1 0.00625394
SEPTIN10 septin 10 0.00625031
MID1 midline 1 0.00623765
ZNF185 zinc finger protein 185 (LIM domain) 0.00622818
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.00620138
PPARG peroxisome proliferator-activated receptor gamma 0.00619474
SPRR3 small proline-rich protein 3 0.00618016
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00616941
PDZD8 PDZ domain containing 8 0.00616769
COL6A3 collagen, type VI, alpha 3 0.00615432
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00615124
EGLN3 egl-9 family hypoxia-inducible factor 3 0.00614662
TRIM29 tripartite motif containing 29 0.00613689
FN1 fibronectin 1 0.00613307
TNNI2 troponin I type 2 (skeletal, fast) 0.00610967
EHD2 EH-domain containing 2 0.00610893
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) 0.00609723
NELL2 NEL-like 2 (chicken) 0.00609459
VAMP8 vesicle-associated membrane protein 8 0.00609082
TPI1 triosephosphate isomerase 1 0.00609077
TPM2 tropomyosin 2 (beta) 0.00608143
ARHGAP29 Rho GTPase activating protein 29 0.0060801
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00607975
HK2 hexokinase 2 0.00607702
PIR pirin (iron-binding nuclear protein) 0.00606825
WASHC4 WASH complex subunit 4 0.00606071
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00605206
SPARCL1 SPARC-like 1 (hevin) 0.00602523
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00602205
SAP30 Sin3A-associated protein, 30kDa 0.00602159
TPSAB1 tryptase alpha/beta 1 0.00600584
FBN2 fibrillin 2 0.00600429
CA9 carbonic anhydrase IX 0.00599406
PSPH phosphoserine phosphatase 0.0059926
TNNT1 troponin T type 1 (skeletal, slow) 0.00598722
AFP alpha-fetoprotein 0.00598115
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 0.00597549
SOWAHC sosondowah ankyrin repeat domain family member C 0.00597367
GSTP1 glutathione S-transferase pi 1 0.00597311
LAMB3 laminin, beta 3 0.00596747
STON1 stonin 1 0.00596633
EIF1AX eukaryotic translation initiation factor 1A, X-linked 0.00595787
IL17RB interleukin 17 receptor B 0.00595159
XIC X chromosome inactivation center 0.00594655
SLC38A1 solute carrier family 38, member 1 0.00594229
SYNPO synaptopodin 0.00592915
APOLD1 apolipoprotein L domain containing 1 0.00592706
BGN biglycan 0.00590754
PALM paralemmin 0.00588787
LPAR1 lysophosphatidic acid receptor 1 0.00588132
COPS7A COP9 signalosome subunit 7A 0.00587859
CA2 carbonic anhydrase II 0.00582465
KCTD12 potassium channel tetramerization domain containing 12 0.00581403
TRH thyrotropin-releasing hormone 0.00580031
LGALS2 lectin, galactoside-binding, soluble, 2 0.00578943
TTN titin 0.0057867
ADCY9 adenylate cyclase 9 0.0057808
HOXB6 homeobox B6 0.00576676
ABLIM1 actin binding LIM protein 1 0.00575332
RHOF ras homolog family member F (in filopodia) 0.00574793
MAST4 microtubule associated serine/threonine kinase family member 4 0.00574655
AHNAK AHNAK nucleoprotein 0.00573851
CPB1 carboxypeptidase B1 (tissue) 0.00573093
KLF6 Kruppel-like factor 6 0.00570366
TMEM14A transmembrane protein 14A 0.00569601
PFKP phosphofructokinase, platelet 0.00569484
TUBA3D tubulin, alpha 3d 0.00569202
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00568882
PCDH17 protocadherin 17 0.00568207
KRT6B keratin 6B, type II 0.00568203
TSPO translocator protein (18kDa) 0.00567463
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00563561
ANXA2 annexin A2 0.00562057
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00561421
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00559593
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00557718
CALML3 calmodulin-like 3 0.00557653
ETHE1 ethylmalonic encephalopathy 1 0.00557098
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00556814
LYPD3 LY6/PLAUR domain containing 3 0.00556494
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00556037
LY6D lymphocyte antigen 6 complex, locus D 0.0055401
DCK deoxycytidine kinase 0.00553867
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00552843
C1QA complement component 1, q subcomponent, A chain 0.00552449
NFE2L2 nuclear factor, erythroid 2-like 2 0.00551431
C9ORF3 chromosome 9 open reading frame 3 0.00551199
CD93 CD93 molecule 0.00550672
HSPA1A heat shock 70kDa protein 1A 0.00547759
FKBP4 FK506 binding protein 4, 59kDa 0.00546875
NUPR1 nuclear protein, transcriptional regulator, 1 0.00545768
SLN sarcolipin 0.0054496
NEFH neurofilament, heavy polypeptide 0.0054415
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) 0.00544047
SDC2 syndecan 2 0.00543448
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00542443
ACTA1 actin, alpha 1, skeletal muscle 0.0054192
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.00541503
CHEK1 checkpoint kinase 1 0.00541182
LOX lysyl oxidase 0.0054082
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00540229
GLTP glycolipid transfer protein 0.00539935
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.00538896
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.0053803
LRRN3 leucine rich repeat neuronal 3 0.0053801
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.00537729
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00537299
ACOX2 acyl-CoA oxidase 2, branched chain 0.00536924
SDC4 syndecan 4 0.00535811

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -0.0293573
EGR3 early growth response 3 -0.0115213
IFI27 interferon, alpha-inducible protein 27 -0.0114754
MYH10 myosin, heavy chain 10, non-muscle -0.0106605
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.0103391
ASPN asporin -0.0103291
EIF5 eukaryotic translation initiation factor 5 -0.010225
THBS2 thrombospondin 2 -0.0100822
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.00985932
MX1 MX dynamin-like GTPase 1 -0.00976994
ESR1 estrogen receptor 1 -0.00952612
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -0.0094652
IFI6 interferon, alpha-inducible protein 6 -0.00945782
BCHE butyrylcholinesterase -0.00940335
E2F2 E2F transcription factor 2 -0.00932675
TXNDC9 thioredoxin domain containing 9 -0.00913121
TXNIP thioredoxin interacting protein -0.00904483
TFPI2 tissue factor pathway inhibitor 2 -0.00888534
CADM1 cell adhesion molecule 1 -0.00882033
KDM5D lysine (K)-specific demethylase 5D -0.00881807
ECM1 extracellular matrix protein 1 -0.00869275
XPO7 exportin 7 -0.00860808
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0085833
FAM3C family with sequence similarity 3, member C -0.00856593
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00850795
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00843711
PROM1 prominin 1 -0.00836152
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00835223
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00834818
MX2 MX dynamin-like GTPase 2 -0.00831972
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0082657
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 -0.0082538
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.00818245
KIAA0125 KIAA0125 -0.00813141
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00801699
ISG15 ISG15 ubiquitin-like modifier -0.00793083
GREB1 growth regulation by estrogen in breast cancer 1 -0.00787715
MPDZ multiple PDZ domain protein -0.00778291
FZD3 frizzled class receptor 3 -0.00774383
LUM lumican -0.00772474
TOP1 topoisomerase (DNA) I -0.00767162
TRIM22 tripartite motif containing 22 -0.00760932
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00757675
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00754367
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00752226
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.00749504
CDC20 cell division cycle 20 -0.00746523
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00736441
MOXD1 monooxygenase, DBH-like 1 -0.00733896
DCN decorin -0.00730679
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 -0.00725846
RCAN1 regulator of calcineurin 1 -0.00723428
DDIT4 DNA-damage-inducible transcript 4 -0.00712502
ZNF512B zinc finger protein 512B -0.00711482
KLF11 Kruppel-like factor 11 -0.00709587
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 -0.00703186
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.00702919
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00702571
CD200 CD200 molecule -0.00699287
GPATCH8 G patch domain containing 8 -0.00697815
FAM46C family with sequence similarity 46, member C -0.00696578
RAI14 retinoic acid induced 14 -0.00695623
NELFCD negative elongation factor complex member C/D -0.00690965
OXTR oxytocin receptor -0.00690089
JCHAIN joining chain of multimeric IgA and IgM -0.00689567
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00687537
TM7SF2 transmembrane 7 superfamily member 2 -0.00683095
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -0.00680824
IFI44L interferon-induced protein 44-like -0.00673519
MPPED2 metallophosphoesterase domain containing 2 -0.00673028
SCAF8 SR-related CTD-associated factor 8 -0.00664141
SLC38A2 solute carrier family 38, member 2 -0.00660608
STAU1 staufen double-stranded RNA binding protein 1 -0.00660573
PHF11 PHD finger protein 11 -0.00657072
TMX4 thioredoxin-related transmembrane protein 4 -0.00652809
BST2 bone marrow stromal cell antigen 2 -0.00648169
ELOVL2 ELOVL fatty acid elongase 2 -0.0064551
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.00643534
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00642021
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00639986
GPNMB glycoprotein (transmembrane) nmb -0.00639669
DBN1 drebrin 1 -0.00639464
PLN phospholamban -0.0063883
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 -0.006386
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00637968
SATB2 SATB homeobox 2 -0.00630731
SFRP1 secreted frizzled-related protein 1 -0.00629538
AFM afamin -0.00624431
ZFP36L2 ZFP36 ring finger protein-like 2 -0.00619212
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A -0.00619041
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00618621
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00617269
LECT2 leukocyte cell-derived chemotaxin 2 -0.00616754
JARID2 jumonji, AT rich interactive domain 2 -0.00615343
TLE4 transducin-like enhancer of split 4 -0.00613761
WDR26 WD repeat domain 26 -0.00610407
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00608732
NPY1R neuropeptide Y receptor Y1 -0.00606663
FAXDC2 fatty acid hydroxylase domain containing 2 -0.00606143
FZD6 frizzled class receptor 6 -0.006052
LAMC1 laminin, gamma 1 (formerly LAMB2) -0.00603127
GANAB glucosidase, alpha; neutral AB -0.00601913
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00598439
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00596103
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00594954
N4BP2L2 NEDD4 binding protein 2-like 2 -0.00594317
SOX10 SRY (sex determining region Y)-box 10 -0.00593515
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.00592965
SOX11 SRY (sex determining region Y)-box 11 -0.00592514
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00591921
CTH cystathionine gamma-lyase -0.005909
SRSF5 serine/arginine-rich splicing factor 5 -0.00590261
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00589796
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00588482
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -0.00586798
RNASET2 ribonuclease T2 -0.00582062
DIO1 deiodinase, iodothyronine, type I -0.00577907
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -0.00577418
PMEL premelanosome protein -0.00576647
CPVL carboxypeptidase, vitellogenic-like -0.00576218
PON1 paraoxonase 1 -0.0057602
VLDLR very low density lipoprotein receptor -0.00572084
TSPYL4 TSPY-like 4 -0.00569427
RPS27L ribosomal protein S27-like -0.00569343
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -0.0056591
MYH11 myosin, heavy chain 11, smooth muscle -0.00565486
C14ORF132 chromosome 14 open reading frame 132 -0.00565462
NRN1 neuritin 1 -0.00565278
MAGEA3 melanoma antigen family A3 -0.00565055
SMAD4 SMAD family member 4 -0.0056166
EGR1 early growth response 1 -0.00561251
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00560591
POGK pogo transposable element with KRAB domain -0.00560405
AKAP7 A kinase (PRKA) anchor protein 7 -0.00559913
CFHR4 complement factor H-related 4 -0.00557833
GRB14 growth factor receptor-bound protein 14 -0.00555709
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -0.00550607
TLK2 tousled-like kinase 2 -0.00550498
PSAT1 phosphoserine aminotransferase 1 -0.00550351
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.00550163
STARD7 StAR-related lipid transfer (START) domain containing 7 -0.00549097
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00548669
GOLGA8A golgin A8 family, member A -0.00547545
DCHS1 dachsous cadherin-related 1 -0.0054737
WARS1 tryptophanyl-tRNA synthetase 1 -0.00546966
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria -0.00546452
ARMC9 armadillo repeat containing 9 -0.00545738
NAMPT nicotinamide phosphoribosyltransferase -0.00544726
ATP5F1E ATP synthase F1 subunit epsilon -0.00543757
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 -0.00543229
RAB5A RAB5A, member RAS oncogene family -0.00540559
OTC ornithine carbamoyltransferase -0.00539015
CREG1 cellular repressor of E1A-stimulated genes 1 -0.00537787
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00535387
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00534369
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00533892
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 -0.00532725
TAC1 tachykinin, precursor 1 -0.00532649
IFIH1 interferon induced with helicase C domain 1 -0.0053261
UCKL1 uridine-cytidine kinase 1-like 1 -0.00531527
GREM1 gremlin 1, DAN family BMP antagonist -0.0053122
LAPTM4B lysosomal protein transmembrane 4 beta -0.00531185
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00529708
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -0.0052871
SYCP2 synaptonemal complex protein 2 -0.0052834
TMEM255A transmembrane protein 255A -0.0052721
CPB2 carboxypeptidase B2 (plasma) -0.00526454
F9 coagulation factor IX -0.00526262
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.00523407
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00522372
MFAP5 microfibrillar associated protein 5 -0.0052223
PROSER1 proline and serine rich 1 -0.0052097
GAS7 growth arrest-specific 7 -0.00520689
LIPG lipase, endothelial -0.00519341
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.00519214
GEM GTP binding protein overexpressed in skeletal muscle -0.00519202
F5 coagulation factor V (proaccelerin, labile factor) -0.00518623
CELF2 CUGBP, Elav-like family member 2 -0.00518037
TDO2 tryptophan 2,3-dioxygenase -0.00517811
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -0.00517039
EFHD1 EF-hand domain family, member D1 -0.00516996
UBR2 ubiquitin protein ligase E3 component n-recognin 2 -0.00516085
DSG2 desmoglein 2 -0.0051497
SFRP4 secreted frizzled-related protein 4 -0.00514209
PLP1 proteolipid protein 1 -0.00513826
ZFAND5 zinc finger, AN1-type domain 5 -0.00512294
IRS2 insulin receptor substrate 2 -0.00511797
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.00511535
TRIM26 tripartite motif containing 26 -0.00511057
SP110 SP110 nuclear body protein -0.00509164
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00509094
SORT1 sortilin 1 -0.00508167
BIN3 bridging integrator 3 -0.00507884
LEFTY1 left-right determination factor 1 -0.00506997
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.00506912
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 -0.00505431
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00504885
RBM38 RNA binding motif protein 38 -0.00501996
ZBTB10 zinc finger and BTB domain containing 10 -0.00501818
SAMHD1 SAM domain and HD domain 1 -0.00501006
NT5E 5'-nucleotidase, ecto (CD73) -0.00500748
METTL5 methyltransferase like 5 -0.00500725
VWA8 von Willebrand factor A domain containing 8 -0.00500666
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa -0.00499581
CHD7 chromodomain helicase DNA binding protein 7 -0.00499083
GYPC glycophorin C (Gerbich blood group) -0.00498146
MARCO macrophage receptor with collagenous structure -0.00498091
MAGEA12 melanoma antigen family A12 -0.00497436
MBD2 methyl-CpG binding domain protein 2 -0.0049697
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.00496588
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -0.00495702
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.00495664
SALL1 spalt-like transcription factor 1 -0.00493904
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -0.00493115
COCH cochlin -0.00492959
MSX1 msh homeobox 1 -0.00492835
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00492649
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.00490714
CRHBP corticotropin releasing hormone binding protein -0.00490259
ZNF394 zinc finger protein 394 -0.00489944
DYNLL1 dynein, light chain, LC8-type 1 -0.00487441
KDM7A lysine (K)-specific demethylase 7A -0.00484333
GLDC glycine dehydrogenase (decarboxylating) -0.00484288
C3 complement component 3 -0.00484174
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.00484042
GYS2 glycogen synthase 2 (liver) -0.00483568
KIAA0226L KIAA0226-like -0.00483194
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 -0.00482606
RUNX1 runt-related transcription factor 1 -0.0048231
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00482024
PCCB propionyl CoA carboxylase, beta polypeptide -0.00481466
TADA2A transcriptional adaptor 2A -0.00481249
RNF130 ring finger protein 130 -0.00480827
GSE1 Gse1 coiled-coil protein -0.00480825
BTBD3 BTB (POZ) domain containing 3 -0.00480204
VCAN versican -0.00480027
IFITM1 interferon induced transmembrane protein 1 -0.00479489
NINL ninein-like -0.00479324
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 -0.00479009
ARID4B AT rich interactive domain 4B (RBP1-like) -0.00476961
AQP1 aquaporin 1 (Colton blood group) -0.00476006
TPX2 TPX2, microtubule-associated -0.00475852
IGFBP5 insulin-like growth factor binding protein 5 -0.00475495
GAS1 growth arrest-specific 1 -0.0047444
HLA-B major histocompatibility complex, class I, B -0.00473981
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A -0.00473438
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00473022
SFTPB surfactant protein B -0.00472703
HEXA hexosaminidase A (alpha polypeptide) -0.00472052
ADAM10 ADAM metallopeptidase domain 10 -0.00471208