MRC1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description mannose receptor, C type 1|The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011] (NCBI Entrez Gene Database, 4360)
External Link https://ncbi.nlm.nih.gov/gene/4360
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Genes

500 genes differentially expressed following the MRC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.0125695
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0102788
PBX1 pre-B-cell leukemia homeobox 1 0.00973224
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00971493
DLK1 delta-like 1 homolog (Drosophila) 0.00920543
DPYD dihydropyrimidine dehydrogenase 0.00919388
NUSAP1 nucleolar and spindle associated protein 1 0.00910044
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00896694
SSBP2 single-stranded DNA binding protein 2 0.00891159
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00884257
CALML5 calmodulin-like 5 0.0082059
HOPX HOP homeobox 0.00792789
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00792469
DEK DEK proto-oncogene 0.007798
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00723733
PRUNE2 prune homolog 2 (Drosophila) 0.00717693
CXCL9 chemokine (C-X-C motif) ligand 9 0.0070259
ENO2 enolase 2 (gamma, neuronal) 0.00697935
MAP7 microtubule-associated protein 7 0.00696396
FASN fatty acid synthase 0.00694315
KIF20A kinesin family member 20A 0.00693993
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00692945
COL1A2 collagen, type I, alpha 2 0.00689674
CDC20 cell division cycle 20 0.0068896
COL4A5 collagen, type IV, alpha 5 0.00675361
TMSB15A thymosin beta 15a 0.0066718
RAD23B RAD23 homolog B (S. cerevisiae) 0.00663486
G6PD glucose-6-phosphate dehydrogenase 0.00660739
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.00659554
BIRC5 baculoviral IAP repeat containing 5 0.00651847
SPTSSA serine palmitoyltransferase, small subunit A 0.00645354
GNAS GNAS complex locus 0.00644571
PCP4 Purkinje cell protein 4 0.00641178
ACP3 acid phosphatase 3 0.00640085
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00639993
NELL2 NEL-like 2 (chicken) 0.00636557
SV2A synaptic vesicle glycoprotein 2A 0.0063051
NMU neuromedin U 0.00622383
AMD1 adenosylmethionine decarboxylase 1 0.00619507
GANAB glucosidase, alpha; neutral AB 0.00607618
TMEM45A transmembrane protein 45A 0.00606724
CCNA2 cyclin A2 0.00606123
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.00604857
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.0060454
VLDLR very low density lipoprotein receptor 0.00603659
PSIP1 PC4 and SFRS1 interacting protein 1 0.00597494
NRGN neurogranin (protein kinase C substrate, RC3) 0.00590607
CKAP4 cytoskeleton-associated protein 4 0.00582001
SREBF1 sterol regulatory element binding transcription factor 1 0.00578776
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.00578077
ARG2 arginase 2 0.00576657
KYNU kynureninase 0.00575581
IDO1 indoleamine 2,3-dioxygenase 1 0.00573449
PTTG1 pituitary tumor-transforming 1 0.00572159
LAPTM4B lysosomal protein transmembrane 4 beta 0.00570853
TYRP1 tyrosinase-related protein 1 0.00569774
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00568994
TSPYL4 TSPY-like 4 0.00567388
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.00565359
LMO3 LIM domain only 3 (rhombotin-like 2) 0.0056322
MMRN1 multimerin 1 0.00560063
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.00557912
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00554593
KRT1 keratin 1, type II 0.00554027
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00553047
PRMT1 protein arginine methyltransferase 1 0.00552718
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00549867
CHGB chromogranin B 0.00549823
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00549178
SPART spartin 0.00547886
NPR3 natriuretic peptide receptor 3 0.00547258
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0054542
SERBP1 SERPINE1 mRNA binding protein 1 0.00545255
HOXB2 homeobox B2 0.0054495
CA11 carbonic anhydrase XI 0.00543354
PRAME preferentially expressed antigen in melanoma 0.00542313
CHKB choline kinase beta 0.0054228
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00539921
MCM2 minichromosome maintenance complex component 2 0.00539601
STXBP2 syntaxin binding protein 2 0.0053671
NCKIPSD NCK interacting protein with SH3 domain 0.00536694
FANCL Fanconi anemia, complementation group L 0.00535475
RPS5 ribosomal protein S5 0.00534855
KLHL23 kelch-like family member 23 0.00531824
CDCA4 cell division cycle associated 4 0.00529921
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.00529831
CD164 CD164 molecule, sialomucin 0.00526737
ARMCX2 armadillo repeat containing, X-linked 2 0.00526368
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00525794
PAX6 paired box 6 0.00521649
CCND1 cyclin D1 0.00520495
CDK19 cyclin-dependent kinase 19 0.00520361
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.00520167
MEIS2 Meis homeobox 2 0.00519446
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00519434
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00518758
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.00518428
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00517947
CXCL11 chemokine (C-X-C motif) ligand 11 0.00515609
KLHDC3 kelch domain containing 3 0.00515059
RAPSN receptor-associated protein of the synapse 0.0051024
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.00509896
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00509391
ORC1 origin recognition complex, subunit 1 0.0050923
S100A7 S100 calcium binding protein A7 0.00504727
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00504676
ZNF750 zinc finger protein 750 0.0050442
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00503168
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00501489
SFTPB surfactant protein B 0.00500537
ISOC1 isochorismatase domain containing 1 0.00500346
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 0.00499996
PCGF2 polycomb group ring finger 2 0.00496524
PRDX2 peroxiredoxin 2 0.00495164
AURKB aurora kinase B 0.00494889
ASF1B anti-silencing function 1B histone chaperone 0.00494708
CENPF centromere protein F, 350/400kDa 0.00494618
INSM1 insulinoma-associated 1 0.00493029
SLC2A4RG SLC2A4 regulator 0.00491851
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00491188
RNF130 ring finger protein 130 0.00490197
LTA4H leukotriene A4 hydrolase 0.00489901
MRTFB myocardin related transcription factor B 0.00486292
CCDC47 coiled-coil domain containing 47 0.00485969
PER3 period circadian clock 3 0.00485894
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.00480139
GIMAP4 GTPase, IMAP family member 4 0.00479297
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.00479034
ACP2 acid phosphatase 2, lysosomal 0.00478914
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00476805
UNC13B unc-13 homolog B (C. elegans) 0.00475992
PRPF19 pre-mRNA processing factor 19 0.00475371
FABP7 fatty acid binding protein 7, brain 0.00473399
IPW imprinted in Prader-Willi syndrome (non-protein coding) 0.0047289
FAM120A family with sequence similarity 120A 0.00472337
NFE2 nuclear factor, erythroid 2 0.00471711
PRC1 protein regulator of cytokinesis 1 0.00470153
SRSF1 serine/arginine-rich splicing factor 1 0.00470146
NIBAN1 niban apoptosis regulator 1 0.00469003
DTWD1 DTW domain containing 1 0.00467474
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.00465426
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00463985
QPCT glutaminyl-peptide cyclotransferase 0.00463926
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.00462354
RNF167 ring finger protein 167 0.00461224
TMEM214 transmembrane protein 214 0.00459921
ZMYM3 zinc finger, MYM-type 3 0.00459486
BCLAF1 BCL2-associated transcription factor 1 0.00459457
RXRA retinoid X receptor, alpha 0.00459107
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.00459069
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.00458822
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.0045713
RPN2 ribophorin II 0.00456077
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.00454727
TSPAN12 tetraspanin 12 0.00454042
PMM2 phosphomannomutase 2 0.00453792
PRPF8 pre-mRNA processing factor 8 0.00453066
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.0045111
CASC3 cancer susceptibility candidate 3 0.0045089
RNASEH2A ribonuclease H2, subunit A 0.00450439
GSTT1 glutathione S-transferase theta 1 0.00449208
C1ORF115 chromosome 1 open reading frame 115 0.00448515
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0044816
ELP1 elongator acetyltransferase complex subunit 1 0.00447722
UQCRC1 ubiquinol-cytochrome c reductase core protein I 0.00447272
CUL4B cullin 4B 0.00447258
BCHE butyrylcholinesterase 0.00445215
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3 0.00444122
CNR1 cannabinoid receptor 1 (brain) 0.00444023
KIF15 kinesin family member 15 0.00443799
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.004427
PDE4D phosphodiesterase 4D, cAMP-specific 0.00442274
NTS neurotensin 0.00441732
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.0044156
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.00441173
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.004409
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00440468
IL13RA2 interleukin 13 receptor, alpha 2 0.00439753
RTN1 reticulon 1 0.00439293
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00437946
KIF4A kinesin family member 4A 0.00436799
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00436427
GPRASP1 G protein-coupled receptor associated sorting protein 1 0.00436356
SFTPA2 surfactant protein A2 0.00435719
NPM3 nucleophosmin/nucleoplasmin 3 0.00435455
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.0043536
SHROOM2 shroom family member 2 0.00435155
OIP5 Opa interacting protein 5 0.00434751
TGM2 transglutaminase 2 0.00434573
MAGEA3 melanoma antigen family A3 0.00433002
PITX1 paired-like homeodomain 1 0.00432933
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00432556
CTDNEP1 CTD nuclear envelope phosphatase 1 0.0043089
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.00430226
LDOC1 leucine zipper, down-regulated in cancer 1 0.00429613
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00428903
LMNB2 lamin B2 0.00427227
EPAS1 endothelial PAS domain protein 1 0.00426465
VDAC3 voltage-dependent anion channel 3 0.00426048
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.00426003
ADAMDEC1 ADAM-like, decysin 1 0.00425787
LMNB1 lamin B1 0.00423787
UNG uracil-DNA glycosylase 0.00423264
ADARB1 adenosine deaminase, RNA-specific, B1 0.00422525
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00421405
ENO1 enolase 1, (alpha) 0.00420935
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.00420468
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.0042008
P4HB prolyl 4-hydroxylase, beta polypeptide 0.00419539
TPX2 TPX2, microtubule-associated 0.0041946
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00419114
PRPF4 pre-mRNA processing factor 4 0.00418141
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.00418084
PTBP1 polypyrimidine tract binding protein 1 0.00417646
STON1 stonin 1 0.00417269
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00416232
KANK2 KN motif and ankyrin repeat domains 2 0.00414961
H2AX H2A.X variant histone 0.00413766
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.00413639
KLK3 kallikrein-related peptidase 3 0.00413391
NPY neuropeptide Y 0.00412351
SRPRA SRP receptor subunit alpha 0.00412165
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00412075
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00411002
WBP5 WW domain binding protein 5 0.00410996
FGFR1 fibroblast growth factor receptor 1 0.0041086
NUCB1 nucleobindin 1 0.00410198
FOXM1 forkhead box M1 0.00409979
SLC38A10 solute carrier family 38, member 10 0.00409516
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00409322
SYNGR3 synaptogyrin 3 0.00409037
PDZRN3 PDZ domain containing ring finger 3 0.00408967
HMG20B high mobility group 20B 0.00408443
ACOX2 acyl-CoA oxidase 2, branched chain 0.00407247
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00406779
FOCAD focadhesin 0.00406564
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 0.00406383
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 0.0040496
ZNF571 zinc finger protein 571 0.00404077
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.00403926
PHB2 prohibitin 2 0.00402641
TMED9 transmembrane emp24 protein transport domain containing 9 0.00402094
GCH1 GTP cyclohydrolase 1 0.00401167
MEN1 multiple endocrine neoplasia I 0.0039899
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.0039801
DENND2B DENN domain containing 2B 0.00397994
TRMT5 tRNA methyltransferase 5 0.00397974
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.00397675
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.00397571
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.00397226

decreased expression

Symbol Name Standardized Value
AREG amphiregulin -0.0155499
ADIRF adipogenesis regulatory factor -0.0145739
IFI27 interferon, alpha-inducible protein 27 -0.0137002
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0132541
HSPA1A heat shock 70kDa protein 1A -0.0128758
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.0106949
HMOX1 heme oxygenase 1 -0.0105982
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0100189
CRYAB crystallin, alpha B -0.00995221
GPX2 glutathione peroxidase 2 -0.00984329
SFRP4 secreted frizzled-related protein 4 -0.00956876
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0095154
G0S2 G0/G1 switch 2 -0.00917085
PLAAT3 phospholipase A and acyltransferase 3 -0.0091477
HIST1H2BD histone cluster 1, H2bd -0.00909644
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00860961
HSPB8 heat shock 22kDa protein 8 -0.00842241
KLF6 Kruppel-like factor 6 -0.00826216
THBS4 thrombospondin 4 -0.00820746
IFI6 interferon, alpha-inducible protein 6 -0.00818894
HIST1H2BK histone cluster 1, H2bk -0.00817414
MX1 MX dynamin-like GTPase 1 -0.00816596
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00798908
LGALS4 lectin, galactoside-binding, soluble, 4 -0.00798471
HIST1H2AC histone cluster 1, H2ac -0.00793847
DEFB1 defensin, beta 1 -0.00790816
RBM34 RNA binding motif protein 34 -0.00788766
ADD3 adducin 3 (gamma) -0.00777919
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.00773561
MET MET proto-oncogene, receptor tyrosine kinase -0.00773331
KRT14 keratin 14, type I -0.00772622
STK17A serine/threonine kinase 17a -0.00770704
COL14A1 collagen, type XIV, alpha 1 -0.00754312
ATF3 activating transcription factor 3 -0.00747319
GPR137B G protein-coupled receptor 137B -0.00739488
S100P S100 calcium binding protein P -0.00738428
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00737272
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00735114
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00723463
SNAI2 snail family zinc finger 2 -0.00717363
JAG1 jagged 1 -0.00714632
BIK BCL2-interacting killer (apoptosis-inducing) -0.00711414
ZBTB18 zinc finger and BTB domain containing 18 -0.00700982
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00693857
MT1M metallothionein 1M -0.00693313
BAMBI BMP and activin membrane-bound inhibitor -0.00692741
EMP1 epithelial membrane protein 1 -0.00692711
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00691345
STC2 stanniocalcin 2 -0.00687318
CHIC2 cysteine-rich hydrophobic domain 2 -0.00676219
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00675777
SCGB2A2 secretoglobin, family 2A, member 2 -0.00674227
IRF7 interferon regulatory factor 7 -0.00671769
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.00671454
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00670874
ZMAT3 zinc finger, matrin-type 3 -0.00660952
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00656505
TRIM22 tripartite motif containing 22 -0.00654574
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00653302
CFD complement factor D (adipsin) -0.00652401
THBD thrombomodulin -0.00647864
RPS27L ribosomal protein S27-like -0.00647591
KRT19 keratin 19, type I -0.00643724
CSRP1 cysteine and glycine-rich protein 1 -0.00640198
AKR1C2 aldo-keto reductase family 1, member C2 -0.00639454
MT1X metallothionein 1X -0.0063801
FGF1 fibroblast growth factor 1 (acidic) -0.00636956
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00636438
LAMC2 laminin, gamma 2 -0.00635884
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00633476
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00629681
ISG15 ISG15 ubiquitin-like modifier -0.006273
ASS1 argininosuccinate synthase 1 -0.00622486
HTRA1 HtrA serine peptidase 1 -0.00622106
MIR22HG MIR22 host gene -0.00621736
PCDH9 protocadherin 9 -0.00621226
GAS6 growth arrest-specific 6 -0.00617567
INHBA inhibin, beta A -0.00615701
AEBP1 AE binding protein 1 -0.00615408
MYO1B myosin IB -0.00615134
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00614591
BUD31 BUD31 homolog (S. cerevisiae) -0.00612575
AOC1 amine oxidase, copper containing 1 -0.0060261
CA2 carbonic anhydrase II -0.00601858
IER5 immediate early response 5 -0.00600527
AKAP12 A kinase (PRKA) anchor protein 12 -0.00600277
PTHLH parathyroid hormone-like hormone -0.00600082
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00599582
CYBA cytochrome b-245, alpha polypeptide -0.00599461
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00595987
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00594334
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00593795
ITM2C integral membrane protein 2C -0.00589943
FHL2 four and a half LIM domains 2 -0.00588384
ANO1 anoctamin 1, calcium activated chloride channel -0.00587983
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00586134
HSPA2 heat shock 70kDa protein 2 -0.00584974
ANXA3 annexin A3 -0.00583016
CTSD cathepsin D -0.00582064
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00580763
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A -0.00580711
CLIC5 chloride intracellular channel 5 -0.00576214
FABP4 fatty acid binding protein 4, adipocyte -0.00574531
GAB2 GRB2-associated binding protein 2 -0.00570669
C14ORF132 chromosome 14 open reading frame 132 -0.0056981
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -0.00569645
AKR1C1 aldo-keto reductase family 1, member C1 -0.00565468
IGF1R insulin-like growth factor 1 receptor -0.00563324
IGFBP6 insulin-like growth factor binding protein 6 -0.00561581
CLEC3B C-type lectin domain family 3, member B -0.00560761
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.0056018
RCAN1 regulator of calcineurin 1 -0.00560026
CCN2 cellular communication network factor 2 -0.00559332
ASPN asporin -0.00553468
SPRY2 sprouty homolog 2 (Drosophila) -0.00553384
TSPAN1 tetraspanin 1 -0.00552623
ZNF706 zinc finger protein 706 -0.00551558
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00547087
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 -0.00546803
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.00544555
TAGLN transgelin -0.00543799
COPZ2 coatomer protein complex, subunit zeta 2 -0.00543635
NUTF2 nuclear transport factor 2 -0.00541611
IFNGR1 interferon gamma receptor 1 -0.00540981
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -0.00540108
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.00540101
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00538072
UPP1 uridine phosphorylase 1 -0.00537717
PTN pleiotrophin -0.00536404
H1-2 H1.2 linker histone, cluster member -0.0053603
ALOX5 arachidonate 5-lipoxygenase -0.00535729
BTG1 B-cell translocation gene 1, anti-proliferative -0.00535552
TP53I3 tumor protein p53 inducible protein 3 -0.00534836
BLNK B-cell linker -0.00533832
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00533353
SLC22A18 solute carrier family 22, member 18 -0.00530644
SLC16A4 solute carrier family 16, member 4 -0.00529799
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00527873
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00523419
THBS2 thrombospondin 2 -0.00521505
NT5E 5'-nucleotidase, ecto (CD73) -0.00520863
COMP cartilage oligomeric matrix protein -0.00520515
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00518987
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00518762
MYC v-myc avian myelocytomatosis viral oncogene homolog -0.00518077
METTL7A methyltransferase like 7A -0.00515892
RGS5 regulator of G-protein signaling 5 -0.0051488
DST dystonin -0.00514496
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00514434
TM4SF1 transmembrane 4 L six family member 1 -0.00513694
FAM107A family with sequence similarity 107, member A -0.00513635
FAM171A1 family with sequence similarity 171, member A1 -0.00512319
MMP19 matrix metallopeptidase 19 -0.00512108
DPYSL2 dihydropyrimidinase-like 2 -0.00511015
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00510326
ECM1 extracellular matrix protein 1 -0.00509731
ZNHIT1 zinc finger, HIT-type containing 1 -0.00509113
C1S complement component 1, s subcomponent -0.00508507
PUF60 poly-U binding splicing factor 60KDa -0.00507918
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.00507643
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00506727
BHLHE41 basic helix-loop-helix family, member e41 -0.00505044
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00503353
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -0.00503346
MFAP3L microfibrillar-associated protein 3-like -0.00502322
OGA O-GlcNAcase -0.00502285
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00502258
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00500757
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00499571
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.00499277
ANK2 ankyrin 2, neuronal -0.00498831
LAMB3 laminin, beta 3 -0.00496796
CEL carboxyl ester lipase -0.00495769
SPON2 spondin 2, extracellular matrix protein -0.00495506
GRAMD2B GRAM domain containing 2B -0.00495026
HIST1H2BH histone cluster 1, H2bh -0.00493028
CCDC90B coiled-coil domain containing 90B -0.0049141
PDGFRB platelet-derived growth factor receptor, beta polypeptide -0.00491349
ITGB4 integrin, beta 4 -0.00490895
PTEN phosphatase and tensin homolog -0.00490774
SLC38A1 solute carrier family 38, member 1 -0.00490101
RBM47 RNA binding motif protein 47 -0.00489679
MXRA7 matrix-remodelling associated 7 -0.00489479
PALLD palladin, cytoskeletal associated protein -0.00489357
OLFML2B olfactomedin-like 2B -0.00489107
AGTR1 angiotensin II receptor, type 1 -0.00489088
RASA4 RAS p21 protein activator 4 -0.00488453
TRIM29 tripartite motif containing 29 -0.00486849
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00486758
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.00485649
SPRR3 small proline-rich protein 3 -0.00485485
CTTN cortactin -0.00485084
DDA1 DET1 and DDB1 associated 1 -0.00484328
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.00483746
MYOF myoferlin -0.0048316
BIRC3 baculoviral IAP repeat containing 3 -0.00481586
TSC22D2 TSC22 domain family, member 2 -0.00481046
ZNF423 zinc finger protein 423 -0.00480861
MVP major vault protein -0.00480524
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00480512
MFAP5 microfibrillar associated protein 5 -0.00480108
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -0.00480092
TSPAN8 tetraspanin 8 -0.00477734
IRF9 interferon regulatory factor 9 -0.0047761
SP100 SP100 nuclear antigen -0.00475217
BCAS1 breast carcinoma amplified sequence 1 -0.00474826
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00474621
PRNP prion protein -0.0047449
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -0.00472954
RNASET2 ribonuclease T2 -0.00472251
MYRF myelin regulatory factor -0.00472188
ARHGAP29 Rho GTPase activating protein 29 -0.00471688
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00468932
ELN elastin -0.00468014
PTGDS prostaglandin D2 synthase 21kDa (brain) -0.0046788
S100A11 S100 calcium binding protein A11 -0.00467174
SCGB2A1 secretoglobin, family 2A, member 1 -0.00464693
CLTB clathrin, light chain B -0.0046446
TMEM243 transmembrane protein 243, mitochondrial -0.00458591
TICAM1 toll-like receptor adaptor molecule 1 -0.00457596
IGFBP4 insulin-like growth factor binding protein 4 -0.0045749
COBL cordon-bleu WH2 repeat protein -0.00457175
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00456905
IL1RN interleukin 1 receptor antagonist -0.00456277
TRAPPC6A trafficking protein particle complex 6A -0.00455734
PDGFA platelet-derived growth factor alpha polypeptide -0.00455144
MXRA5 matrix-remodelling associated 5 -0.00454487
ELOC elongin C -0.00453651
KLK10 kallikrein-related peptidase 10 -0.00453451
PLXDC1 plexin domain containing 1 -0.0045242
KLF4 Kruppel-like factor 4 (gut) -0.00451532
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.00450891
KLF2 Kruppel-like factor 2 -0.00449423
SAMD9 sterile alpha motif domain containing 9 -0.00449152
FCGRT Fc fragment of IgG, receptor, transporter, alpha -0.00448326
RAP2B RAP2B, member of RAS oncogene family -0.00447402
AK1 adenylate kinase 1 -0.00447382
AKR1C3 aldo-keto reductase family 1, member C3 -0.00446979
RRAGC Ras-related GTP binding C -0.00446401
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.00445759
KIAA0040 KIAA0040 -0.00443902
TTC39A tetratricopeptide repeat domain 39A -0.00443066
TIGAR TP53 induced glycolysis regulatory phosphatase -0.00441702
MME membrane metallo-endopeptidase -0.00441599
RND3 Rho family GTPase 3 -0.00440679
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0043997
TRIP6 thyroid hormone receptor interactor 6 -0.00439796
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.00439647
SOX4 SRY (sex determining region Y)-box 4 -0.00439135
APOL2 apolipoprotein L, 2 -0.00438858