MRC2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description mannose receptor, C type 2|This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012] (NCBI Entrez Gene Database, 9902)
External Link https://ncbi.nlm.nih.gov/gene/9902
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Genes

499 genes differentially expressed following the MRC2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
JCHAIN joining chain of multimeric IgA and IgM 0.014978
CD320 CD320 molecule 0.0137922
CAV1 caveolin 1, caveolae protein, 22kDa 0.0133823
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0113921
IGFBP4 insulin-like growth factor binding protein 4 0.0109778
ADIRF adipogenesis regulatory factor 0.0103913
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0102411
CXCL9 chemokine (C-X-C motif) ligand 9 0.0102407
NTS neurotensin 0.00992543
CDCA4 cell division cycle associated 4 0.0096186
CCL19 chemokine (C-C motif) ligand 19 0.00938327
CXCL13 chemokine (C-X-C motif) ligand 13 0.00903453
TFF3 trefoil factor 3 (intestinal) 0.00900399
FBLN1 fibulin 1 0.00897713
COL6A2 collagen, type VI, alpha 2 0.00885572
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00883943
PIR pirin (iron-binding nuclear protein) 0.00874636
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00871026
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 0.00865334
RBM47 RNA binding motif protein 47 0.00859338
PLVAP plasmalemma vesicle associated protein 0.00857599
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.00851512
SPON2 spondin 2, extracellular matrix protein 0.0083923
BIRC3 baculoviral IAP repeat containing 3 0.00838916
DUSP5 dual specificity phosphatase 5 0.00838043
TMEM106C transmembrane protein 106C 0.00834555
ZBTB18 zinc finger and BTB domain containing 18 0.00827401
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.00827039
MCOLN1 mucolipin 1 0.00822768
TYMP thymidine phosphorylase 0.00817982
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.00812619
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00791064
SLAMF7 SLAM family member 7 0.00787615
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00783397
RAB38 RAB38, member RAS oncogene family 0.00780103
TNC tenascin C 0.00776417
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.00769724
PPARG peroxisome proliferator-activated receptor gamma 0.00767115
CXCL14 chemokine (C-X-C motif) ligand 14 0.00765303
VWF von Willebrand factor 0.00764461
REG1A regenerating islet-derived 1 alpha 0.00762735
TSPAN7 tetraspanin 7 0.00760788
SEPTIN10 septin 10 0.00754
CFD complement factor D (adipsin) 0.00752441
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00745396
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00737104
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.00732313
PDLIM4 PDZ and LIM domain 4 0.00728105
TPSAB1 tryptase alpha/beta 1 0.00726425
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 0.007256
CXCL11 chemokine (C-X-C motif) ligand 11 0.00725581
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00724507
JAG2 jagged 2 0.00719097
C1QB complement component 1, q subcomponent, B chain 0.00711654
AIM2 absent in melanoma 2 0.00711109
TRIB2 tribbles pseudokinase 2 0.00702092
LGALS4 lectin, galactoside-binding, soluble, 4 0.00700541
ELN elastin 0.00697505
CAV2 caveolin 2 0.0069729
DNASE1L3 deoxyribonuclease I-like 3 0.00695196
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.00693935
ZNF532 zinc finger protein 532 0.00693509
DHCR24 24-dehydrocholesterol reductase 0.00688662
OLFM1 olfactomedin 1 0.00688015
CCNF cyclin F 0.00686657
FKBP9 FK506 binding protein 9, 63 kDa 0.00686281
MET MET proto-oncogene, receptor tyrosine kinase 0.00681195
PLA1A phospholipase A1 member A 0.00680882
OLFM4 olfactomedin 4 0.00679922
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00679138
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00678108
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.00673931
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.00672002
CCL8 chemokine (C-C motif) ligand 8 0.00671591
TNS1 tensin 1 0.00671033
PCGF2 polycomb group ring finger 2 0.00670692
NCAPG non-SMC condensin I complex, subunit G 0.00670215
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.00670165
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.00669535
CLEC10A C-type lectin domain family 10, member A 0.00668414
ANPEP alanyl (membrane) aminopeptidase 0.0066717
SOCS1 suppressor of cytokine signaling 1 0.00666082
SMS spermine synthase 0.00664623
ACADVL acyl-CoA dehydrogenase, very long chain 0.0066386
NOTCH3 notch 3 0.00662983
GAS6 growth arrest-specific 6 0.00655024
CHN1 chimerin 1 0.00647141
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00647053
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00646845
VCAM1 vascular cell adhesion molecule 1 0.00645624
CD209 CD209 molecule 0.00645044
C1QA complement component 1, q subcomponent, A chain 0.00640565
LTBP2 latent transforming growth factor beta binding protein 2 0.0064036
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.00639756
TSPAN4 tetraspanin 4 0.00638579
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.00636985
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00636497
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00632478
MDFIC MyoD family inhibitor domain containing 0.00632317
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00631754
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.0062873
GTSE1 G-2 and S-phase expressed 1 0.00628296
ENO2 enolase 2 (gamma, neuronal) 0.00628073
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) 0.00626701
REG1B regenerating islet-derived 1 beta 0.00626446
G0S2 G0/G1 switch 2 0.0062633
FABP4 fatty acid binding protein 4, adipocyte 0.00625702
REG3A regenerating islet-derived 3 alpha 0.00624841
KIAA0232 KIAA0232 0.00624502
CD8A CD8a molecule 0.00624233
COMP cartilage oligomeric matrix protein 0.00623313
JMJD6 jumonji domain containing 6 0.00621155
TMEM164 transmembrane protein 164 0.00620771
ITGA7 integrin, alpha 7 0.00618225
IGFBP6 insulin-like growth factor binding protein 6 0.00617744
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.0061297
CHRDL1 chordin-like 1 0.00608945
KIF18B kinesin family member 18B 0.00605565
RACGAP1 Rac GTPase activating protein 1 0.00605335
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.00602404
MCAM melanoma cell adhesion molecule 0.0060133
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) 0.00599361
RASIP1 Ras interacting protein 1 0.00598215
CCL5 chemokine (C-C motif) ligand 5 0.00598209
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00597628
PSPH phosphoserine phosphatase 0.00596771
MMP3 matrix metallopeptidase 3 0.00595822
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.00595658
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00594921
GPX2 glutathione peroxidase 2 0.00594901
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00592987
CDC25B cell division cycle 25B 0.00591482
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00587931
SYBU syntabulin (syntaxin-interacting) 0.00587715
REX1BD required for excision 1-B domain containing 0.00586883
TRIB3 tribbles pseudokinase 3 0.0058604
PRR5 proline rich 5 (renal) 0.00585086
TFF1 trefoil factor 1 0.00581591
KIAA0930 KIAA0930 0.00578194
IL7R interleukin 7 receptor 0.00577811
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.00577724
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00575266
SPC25 SPC25, NDC80 kinetochore complex component 0.00574497
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00571835
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00571213
MAT2A methionine adenosyltransferase II, alpha 0.00570984
CCL4 chemokine (C-C motif) ligand 4 0.00569459
FOXM1 forkhead box M1 0.00569409
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.005693
EHD2 EH-domain containing 2 0.005671
MMP1 matrix metallopeptidase 1 0.0056582
IL7 interleukin 7 0.00565554
CCN3 cellular communication network factor 3 0.0056502
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.00563513
CA12 carbonic anhydrase XII 0.00563006
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.00562087
SOAT1 sterol O-acyltransferase 1 0.00562069
FXYD2 FXYD domain containing ion transport regulator 2 0.00561706
SLURP1 secreted LY6/PLAUR domain containing 1 0.00560736
PNPLA6 patatin-like phospholipase domain containing 6 0.00559887
PRPF3 pre-mRNA processing factor 3 0.00558502
CCL13 chemokine (C-C motif) ligand 13 0.00558433
CTBP2 C-terminal binding protein 2 0.00557576
SETBP1 SET binding protein 1 0.00557061
NMU neuromedin U 0.00555668
NKG7 natural killer cell granule protein 7 0.00555423
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 0.00553493
C1R complement component 1, r subcomponent 0.00551211
RAD51AP1 RAD51 associated protein 1 0.00550983
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.00550131
KIF23 kinesin family member 23 0.0054959
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00547643
KLHDC2 kelch domain containing 2 0.0054696
FANCG Fanconi anemia, complementation group G 0.00545916
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.00543934
COL14A1 collagen, type XIV, alpha 1 0.00543792
CPT1A carnitine palmitoyltransferase 1A (liver) 0.00542673
NCAPD3 non-SMC condensin II complex, subunit D3 0.00542112
DBF4 DBF4 zinc finger 0.00542084
P3H2 prolyl 3-hydroxylase 2 0.00541663
INSIG1 insulin induced gene 1 0.00541657
ECT2 epithelial cell transforming 2 0.00540575
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.00537745
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00537465
GSDMD gasdermin D 0.00537428
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00537288
EPHB2 EPH receptor B2 0.00536838
IGFBP5 insulin-like growth factor binding protein 5 0.00536143
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00536017
CLEC3B C-type lectin domain family 3, member B 0.00535709
PMEL premelanosome protein 0.00534758
IL11RA interleukin 11 receptor, alpha 0.00534324
MAOA monoamine oxidase A 0.00534182
THBD thrombomodulin 0.0053403
CPB1 carboxypeptidase B1 (tissue) 0.00533816
XCL1 chemokine (C motif) ligand 1 0.00533553
NEO1 neogenin 1 0.00532886
UPP1 uridine phosphorylase 1 0.0053078
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00529569
WDR13 WD repeat domain 13 0.00529122
TST thiosulfate sulfurtransferase (rhodanese) 0.00527628
MICU2 mitochondrial calcium uptake 2 0.00527458
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.00524776
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00524102
AOC3 amine oxidase, copper containing 3 0.00522917
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.00522582
MALL mal, T-cell differentiation protein-like 0.00521644
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00519843
C2CD5 C2 calcium-dependent domain containing 5 0.0051922
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.00518825
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00518568
PSIP1 PC4 and SFRS1 interacting protein 1 0.00518038
ZMIZ1 zinc finger, MIZ-type containing 1 0.00517416
KIF11 kinesin family member 11 0.00516594
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.00516472
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.00515682
EPHX2 epoxide hydrolase 2, cytoplasmic 0.00514923
C1QTNF1 C1q and tumor necrosis factor related protein 1 0.00514295
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.0051394
IL18RAP interleukin 18 receptor accessory protein 0.0051219
CENPM centromere protein M 0.00511585
ACOT7 acyl-CoA thioesterase 7 0.00511496
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.00511208
ARL4A ADP-ribosylation factor-like 4A 0.0051116
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00510826
STK17A serine/threonine kinase 17a 0.00509752
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.00509564
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00506742
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.00506652
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 0.00506322
C1ORF115 chromosome 1 open reading frame 115 0.00506276
GRAMD4 GRAM domain containing 4 0.00506051
COL4A2 collagen, type IV, alpha 2 0.00505058
TMX1 thioredoxin-related transmembrane protein 1 0.00503978
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.00502654
FAM13A family with sequence similarity 13, member A 0.00501902
TM4SF4 transmembrane 4 L six family member 4 0.00500587
ZNF217 zinc finger protein 217 0.00499909
NSD2 nuclear receptor binding SET domain protein 2 0.00499624
CIDEA cell death-inducing DFFA-like effector a 0.0049854
CRIP2 cysteine-rich protein 2 0.00495677
CISH cytokine inducible SH2-containing protein 0.00495632
RAB20 RAB20, member RAS oncogene family 0.00495412
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.0049523
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00494804
RPA1 replication protein A1, 70kDa 0.00493573
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.0049289
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.00492234
RALB v-ral simian leukemia viral oncogene homolog B 0.00492213

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -0.0337368
MAP7 microtubule-associated protein 7 -0.0193322
PROM1 prominin 1 -0.0148431
PEG3 paternally expressed 3 -0.0137612
TACSTD2 tumor-associated calcium signal transducer 2 -0.0122699
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0121541
LTF lactotransferrin -0.0114653
FOLR1 folate receptor 1 (adult) -0.0114405
SCGB2A1 secretoglobin, family 2A, member 1 -0.0111654
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.0111296
TNNC1 troponin C type 1 (slow) -0.0109892
VCAN versican -0.0104727
S100A8 S100 calcium binding protein A8 -0.010396
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -0.00993593
CEMIP cell migration inducing protein, hyaluronan binding -0.00984001
KRT23 keratin 23, type I -0.00978433
S100P S100 calcium binding protein P -0.00969511
DLK1 delta-like 1 homolog (Drosophila) -0.00952385
CLDN10 claudin 10 -0.00941357
MSLN mesothelin -0.00935435
RFTN1 raftlin, lipid raft linker 1 -0.00925643
BMP4 bone morphogenetic protein 4 -0.00917595
MPO myeloperoxidase -0.008971
CD14 CD14 molecule -0.00889285
SGK1 serum/glucocorticoid regulated kinase 1 -0.00886564
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00874694
OXA1L oxidase (cytochrome c) assembly 1-like -0.00869507
WIF1 WNT inhibitory factor 1 -0.00857277
CCNG1 cyclin G1 -0.008474
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00846345
CLDN7 claudin 7 -0.00845096
SLPI secretory leukocyte peptidase inhibitor -0.00838778
IFITM3 interferon induced transmembrane protein 3 -0.00835321
PADI2 peptidyl arginine deiminase, type II -0.00827643
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00818662
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00814285
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00803071
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00800412
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00797597
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00797224
RGCC regulator of cell cycle -0.00793643
LRRN3 leucine rich repeat neuronal 3 -0.00790451
EMX2 empty spiracles homeobox 2 -0.00787209
FOXC1 forkhead box C1 -0.00772525
KRT19 keratin 19, type I -0.00769918
SH3BGR SH3 domain binding glutamate-rich protein -0.00769535
S100A7 S100 calcium binding protein A7 -0.00768988
BAX BCL2-associated X protein -0.00763793
RGS4 regulator of G-protein signaling 4 -0.00763258
NEBL nebulette -0.00762341
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00759047
CNTN1 contactin 1 -0.0075623
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00754426
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00749357
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.00748002
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00746995
COX5A cytochrome c oxidase subunit Va -0.00746084
CXADR coxsackie virus and adenovirus receptor -0.00744312
ECM1 extracellular matrix protein 1 -0.00740464
TAGLN2 transgelin 2 -0.00738451
PAM peptidylglycine alpha-amidating monooxygenase -0.00738277
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 -0.00737322
DACH1 dachshund family transcription factor 1 -0.00735186
INHBA inhibin, beta A -0.00734679
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00729328
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.00729094
FABP7 fatty acid binding protein 7, brain -0.00725778
CNR1 cannabinoid receptor 1 (brain) -0.00725596
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 -0.00724166
FILIP1L filamin A interacting protein 1-like -0.00724021
SSBP2 single-stranded DNA binding protein 2 -0.00721974
TNNT1 troponin T type 1 (skeletal, slow) -0.0072099
TMEM47 transmembrane protein 47 -0.00719698
GFAP glial fibrillary acidic protein -0.00716314
TRPS1 trichorhinophalangeal syndrome I -0.00715799
S100A10 S100 calcium binding protein A10 -0.00714122
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00711139
KLF9 Kruppel-like factor 9 -0.00707883
LZTS3 leucine zipper, putative tumor suppressor family member 3 -0.00707799
AQP4 aquaporin 4 -0.00707288
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00706359
FAM198B family with sequence similarity 198, member B -0.00705179
RHOBTB3 Rho-related BTB domain containing 3 -0.0070403
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00701598
GLIPR1 GLI pathogenesis-related 1 -0.00701471
CD302 CD302 molecule -0.00698985
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.0069541
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00694636
ANGPT1 angiopoietin 1 -0.00694343
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.00692247
B2M beta-2-microglobulin -0.00688814
DKK3 dickkopf WNT signaling pathway inhibitor 3 -0.00688112
ATP5F1C ATP synthase F1 subunit gamma -0.00688057
BAALC brain and acute leukemia, cytoplasmic -0.00686944
HOPX HOP homeobox -0.0068614
BMP7 bone morphogenetic protein 7 -0.00684606
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -0.00676193
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.0067365
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0067192
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00669842
ABAT 4-aminobutyrate aminotransferase -0.00665375
AKIRIN1 akirin 1 -0.00664021
MEIS1 Meis homeobox 1 -0.0066361
SCD5 stearoyl-CoA desaturase 5 -0.00662843
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00661491
CCNA1 cyclin A1 -0.00660563
ZMAT3 zinc finger, matrin-type 3 -0.00659521
FN1 fibronectin 1 -0.00659383
MT1F metallothionein 1F -0.00659237
NPR3 natriuretic peptide receptor 3 -0.00658418
PERP PERP, TP53 apoptosis effector -0.0065747
MKNK2 MAP kinase interacting serine/threonine kinase 2 -0.00656987
PHYH phytanoyl-CoA 2-hydroxylase -0.00654622
C1ORF56 chromosome 1 open reading frame 56 -0.00653871
MBD2 methyl-CpG binding domain protein 2 -0.00652207
HLA-A major histocompatibility complex, class I, A -0.0064961
MUC16 mucin 16, cell surface associated -0.00649213
MLF1 myeloid leukemia factor 1 -0.00645014
C8ORF4 chromosome 8 open reading frame 4 -0.00640695
ZNF91 zinc finger protein 91 -0.00639957
EIF3H eukaryotic translation initiation factor 3, subunit H -0.00638734
AUTS2 autism susceptibility candidate 2 -0.00635047
ABLIM1 actin binding LIM protein 1 -0.00633761
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00632231
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.00629074
BCAS1 breast carcinoma amplified sequence 1 -0.00629016
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00628472
TENT5A terminal nucleotidyltransferase 5A -0.006264
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00625569
ATF3 activating transcription factor 3 -0.00625203
FNDC3B fibronectin type III domain containing 3B -0.00624538
ACTA1 actin, alpha 1, skeletal muscle -0.00624534
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.00623637
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -0.0062054
EXPH5 exophilin 5 -0.00620444
CD59 CD59 molecule, complement regulatory protein -0.00619992
SCAMP1 secretory carrier membrane protein 1 -0.00617188
TLR4 toll-like receptor 4 -0.00613781
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00613332
HCRTR1 hypocretin (orexin) receptor 1 -0.00613271
DOK5 docking protein 5 -0.00611553
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00611544
MAP9 microtubule-associated protein 9 -0.00610968
IL17RA interleukin 17 receptor A -0.00606348
RPL14 ribosomal protein L14 -0.00605875
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00605872
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00605711
ATP5F1E ATP synthase F1 subunit epsilon -0.00605651
IFITM1 interferon induced transmembrane protein 1 -0.00603778
GPM6A glycoprotein M6A -0.00603373
CALB1 calbindin 1, 28kDa -0.00603369
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00602469
EN1 engrailed homeobox 1 -0.00600906
THBS2 thrombospondin 2 -0.00600905
KRT5 keratin 5, type II -0.00600644
ATP5MG ATP synthase membrane subunit g -0.0059904
SLN sarcolipin -0.00598609
CLDN3 claudin 3 -0.00598183
MFAP3L microfibrillar-associated protein 3-like -0.00595724
ISG15 ISG15 ubiquitin-like modifier -0.00592335
ZIC1 Zic family member 1 -0.00591126
RIPK2 receptor-interacting serine-threonine kinase 2 -0.00588931
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 -0.00586623
ART3 ADP-ribosyltransferase 3 -0.0058653
HMOX1 heme oxygenase 1 -0.00585788
ANXA1 annexin A1 -0.00585482
TJP2 tight junction protein 2 -0.00585462
EFNA1 ephrin-A1 -0.00584571
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00583971
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00583585
MOXD1 monooxygenase, DBH-like 1 -0.005822
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00581495
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -0.00578183
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00577014
FOXG1 forkhead box G1 -0.00575594
DTNA dystrobrevin, alpha -0.00575102
ESRP1 epithelial splicing regulatory protein 1 -0.00574846
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00573633
MAL mal, T-cell differentiation protein -0.00573584
EPCAM epithelial cell adhesion molecule -0.00573081
PDZD2 PDZ domain containing 2 -0.00571614
PNMA2 paraneoplastic Ma antigen 2 -0.00569899
NR1D2 nuclear receptor subfamily 1, group D, member 2 -0.00569341
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00568668
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -0.00566588
CCL14 chemokine (C-C motif) ligand 14 -0.00566038
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00565757
IRF6 interferon regulatory factor 6 -0.0056497
PHACTR2 phosphatase and actin regulator 2 -0.00564772
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.00564729
CFAP20 cilia and flagella associated protein 20 -0.00564664
PLAUR plasminogen activator, urokinase receptor -0.00563408
PRMT1 protein arginine methyltransferase 1 -0.00563242
FLRT3 fibronectin leucine rich transmembrane protein 3 -0.00562983
TMEM260 transmembrane protein 260 -0.00560898
LPPR4 lipid phosphate phosphatase-related protein type 4 -0.00558328
ZNF83 zinc finger protein 83 -0.005579
KLHL41 kelch-like family member 41 -0.00556684
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00556679
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.0055665
FZD3 frizzled class receptor 3 -0.00556391
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 -0.00553802
SCRG1 stimulator of chondrogenesis 1 -0.00553333
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00553051
PPP1R9A protein phosphatase 1, regulatory subunit 9A -0.00552876
WNT2 wingless-type MMTV integration site family member 2 -0.00552825
YBX1 Y box binding protein 1 -0.00552788
GNG5 guanine nucleotide binding protein (G protein), gamma 5 -0.00551716
PLLP plasmolipin -0.0055117
LRRC17 leucine rich repeat containing 17 -0.00548186
GAP43 growth associated protein 43 -0.00548107
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 -0.00547198
WASHC4 WASH complex subunit 4 -0.00543947
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -0.00542739
ZBTB10 zinc finger and BTB domain containing 10 -0.0054272
EGFL6 EGF-like-domain, multiple 6 -0.00542224
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.0054117
ERP44 endoplasmic reticulum protein 44 -0.00540772
SEPTIN9 septin 9 -0.00540586
NRCAM neuronal cell adhesion molecule -0.00539291
ADAM10 ADAM metallopeptidase domain 10 -0.00538685
CAPN3 calpain 3, (p94) -0.00538643
SPRR3 small proline-rich protein 3 -0.00538202
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00536742
ZNF512B zinc finger protein 512B -0.00534178
NME5 NME/NM23 family member 5 -0.00533676
MYH10 myosin, heavy chain 10, non-muscle -0.00533119
INAVA innate immunity activator -0.00532865
ACTN2 actinin, alpha 2 -0.00532476
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.005319
COBL cordon-bleu WH2 repeat protein -0.00531669
ACYP2 acylphosphatase 2, muscle type -0.00531139
C6ORF48 chromosome 6 open reading frame 48 -0.0053097
TSPAN1 tetraspanin 1 -0.00530914
TEX10 testis expressed 10 -0.00530845
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00528403
TREM1 triggering receptor expressed on myeloid cells 1 -0.00527387
THBS1 thrombospondin 1 -0.00527013
CDH3 cadherin 3, type 1, P-cadherin (placental) -0.00526086
F5 coagulation factor V (proaccelerin, labile factor) -0.00525972
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.00525873
FKBP10 FK506 binding protein 10, 65 kDa -0.00525243
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -0.00524934
PTPRD protein tyrosine phosphatase, receptor type, D -0.00524417
SOSTDC1 sclerostin domain containing 1 -0.00523721
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 -0.00523319
ZNF264 zinc finger protein 264 -0.00522831
SRPX2 sushi-repeat containing protein, X-linked 2 -0.00522022
GDI2 GDP dissociation inhibitor 2 -0.00521518
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) -0.00520121