MRE11 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
External Link https://ncbi.nlm.nih.gov/gene/4361
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Genes

499 genes differentially expressed following the MRE11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center 0.0229953
TUBB2A tubulin, beta 2A class IIa 0.0181058
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0171859
CLCA4 chloride channel accessory 4 0.0154299
CXCL8 chemokine (C-X-C motif) ligand 8 0.0153307
CLDN8 claudin 8 0.0134774
ATF3 activating transcription factor 3 0.0134755
FCGBP Fc fragment of IgG binding protein 0.0127995
ADM adrenomedullin 0.0122468
CRYAB crystallin, alpha B 0.0119877
MAP7 microtubule-associated protein 7 0.0119839
PEG10 paternally expressed 10 0.0118434
H1-2 H1.2 linker histone, cluster member 0.0116612
KYNU kynureninase 0.0114773
STC1 stanniocalcin 1 0.011165
EHF ets homologous factor 0.0111041
MUC4 mucin 4, cell surface associated 0.0110064
CSTA cystatin A (stefin A) 0.011
CSRP2 cysteine and glycine-rich protein 2 0.0109618
KLF4 Kruppel-like factor 4 (gut) 0.0107538
HSPB1 heat shock 27kDa protein 1 0.0107292
RCAN1 regulator of calcineurin 1 0.0106883
POSTN periostin, osteoblast specific factor 0.0106107
MT1X metallothionein 1X 0.010558
CLDN7 claudin 7 0.0105557
SGCE sarcoglycan, epsilon 0.0104994
DHRS9 dehydrogenase/reductase (SDR family) member 9 0.0103803
FABP7 fatty acid binding protein 7, brain 0.0103607
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0102578
S100A10 S100 calcium binding protein A10 0.0102518
GRB7 growth factor receptor-bound protein 7 0.0101611
TSPAN1 tetraspanin 1 0.0100476
MUC2 mucin 2, oligomeric mucus/gel-forming 0.0100006
KRT81 keratin 81, type II 0.00998841
S100A9 S100 calcium binding protein A9 0.00993025
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.0098494
EIF5A eukaryotic translation initiation factor 5A 0.00980219
BAMBI BMP and activin membrane-bound inhibitor 0.0097137
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00967217
BTG1 B-cell translocation gene 1, anti-proliferative 0.00961728
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00949343
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00948823
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00947235
F3 coagulation factor III (thromboplastin, tissue factor) 0.00943808
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.00942704
GOLT1B golgi transport 1B 0.00926676
PIGR polymeric immunoglobulin receptor 0.00918628
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 0.00904579
ETHE1 ethylmalonic encephalopathy 1 0.00902357
CAST calpastatin 0.00901935
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.00891902
ZG16 zymogen granule protein 16 0.00891372
CCL20 chemokine (C-C motif) ligand 20 0.00889851
CHI3L2 chitinase 3-like 2 0.00887415
SGK1 serum/glucocorticoid regulated kinase 1 0.00884829
LXN latexin 0.00868616
CA2 carbonic anhydrase II 0.00862778
MREG melanoregulin 0.00861926
DHDDS dehydrodolichyl diphosphate synthase 0.00861855
CA4 carbonic anhydrase IV 0.00861116
NRCAM neuronal cell adhesion molecule 0.00859579
CD14 CD14 molecule 0.00858702
C3 complement component 3 0.00858658
ADAMDEC1 ADAM-like, decysin 1 0.00847509
RB1 retinoblastoma 1 0.00846594
MEN1 multiple endocrine neoplasia I 0.00844374
ZMAT3 zinc finger, matrin-type 3 0.00842326
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00840915
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00840492
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00838355
ZIC1 Zic family member 1 0.00835807
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.00832089
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00832086
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00826593
YBX3 Y box binding protein 3 0.00825272
CLEC2B C-type lectin domain family 2, member B 0.00824284
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00822606
S100A14 S100 calcium binding protein A14 0.00820302
PALLD palladin, cytoskeletal associated protein 0.00815537
GPNMB glycoprotein (transmembrane) nmb 0.0081483
SLC35G2 solute carrier family 35, member G2 0.00813239
CHGB chromogranin B 0.00809384
GLUL glutamate-ammonia ligase 0.00808227
CA12 carbonic anhydrase XII 0.00802765
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.007993
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.00799115
KRT15 keratin 15, type I 0.00798549
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00797691
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.00796129
TSC22D1 TSC22 domain family, member 1 0.00792717
DUSP10 dual specificity phosphatase 10 0.00792134
CLCA1 chloride channel accessory 1 0.00790377
FGF1 fibroblast growth factor 1 (acidic) 0.00789843
TCL1A T-cell leukemia/lymphoma 1A 0.00789101
PROM1 prominin 1 0.00785259
HOXC6 homeobox C6 0.00784975
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00784968
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00781829
TRIB2 tribbles pseudokinase 2 0.00777745
HSPA2 heat shock 70kDa protein 2 0.00776281
PLK1 polo-like kinase 1 0.00775063
EDN3 endothelin 3 0.00769615
CXADR coxsackie virus and adenovirus receptor 0.00761643
CREB3L2 cAMP responsive element binding protein 3-like 2 0.00759224
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00756159
LCN2 lipocalin 2 0.00755098
PCDH9 protocadherin 9 0.00752913
NMD3 NMD3 ribosome export adaptor 0.00750657
LTF lactotransferrin 0.00750457
PODXL podocalyxin-like 0.00749003
CD59 CD59 molecule, complement regulatory protein 0.00748962
GSN gelsolin 0.00744116
NCK1 NCK adaptor protein 1 0.00743374
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.00740898
S100B S100 calcium binding protein B 0.0074032
SCPEP1 serine carboxypeptidase 1 0.00730403
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00729212
CXCL12 chemokine (C-X-C motif) ligand 12 0.00727747
ZYX zyxin 0.00726476
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00726022
NRN1 neuritin 1 0.00724315
KLHL24 kelch-like family member 24 0.00723005
SOD2 superoxide dismutase 2, mitochondrial 0.00720722
KLF9 Kruppel-like factor 9 0.00711657
BLNK B-cell linker 0.007093
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00707787
CHP1 calcineurin-like EF-hand protein 1 0.0070628
CD36 CD36 molecule (thrombospondin receptor) 0.00705227
TUBB2B tubulin, beta 2B class IIb 0.00697592
HIST1H2BD histone cluster 1, H2bd 0.00695757
ANGPT1 angiopoietin 1 0.00695694
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.00694754
FGF13 fibroblast growth factor 13 0.00694076
LYN LYN proto-oncogene, Src family tyrosine kinase 0.00692931
GUCA2A guanylate cyclase activator 2A (guanylin) 0.0069181
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00688927
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00688612
EMP1 epithelial membrane protein 1 0.0068627
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.0068596
IRF6 interferon regulatory factor 6 0.00684674
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00682937
PRNP prion protein 0.00681842
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00680983
GPM6A glycoprotein M6A 0.00680786
MMP9 matrix metallopeptidase 9 0.00680682
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00680169
JUNB jun B proto-oncogene 0.00679103
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00676617
TCTA T-cell leukemia translocation altered 0.0067487
SOX10 SRY (sex determining region Y)-box 10 0.00672958
PTHLH parathyroid hormone-like hormone 0.00670319
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00669379
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.00666834
AQP8 aquaporin 8 0.00665946
MYO1B myosin IB 0.00664159
MFAP5 microfibrillar associated protein 5 0.00663174
RGCC regulator of cell cycle 0.006621
RIMS3 regulating synaptic membrane exocytosis 3 0.00660515
PTPN7 protein tyrosine phosphatase, non-receptor type 7 0.00660414
IQCG IQ motif containing G 0.0065738
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.00656479
EGR1 early growth response 1 0.00656357
FXYD3 FXYD domain containing ion transport regulator 3 0.00656161
STMN2 stathmin 2 0.00655393
CRABP2 cellular retinoic acid binding protein 2 0.00654614
KLF6 Kruppel-like factor 6 0.0065451
TPBG trophoblast glycoprotein 0.00652832
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00648811
IFRD1 interferon-related developmental regulator 1 0.00648684
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00646933
ESRP1 epithelial splicing regulatory protein 1 0.00644827
SATB2 SATB homeobox 2 0.00643825
VGLL4 vestigial-like family member 4 0.00642205
PI3 peptidase inhibitor 3, skin-derived 0.00637797
ROPN1B rhophilin associated tail protein 1B 0.00636021
UBE2S ubiquitin-conjugating enzyme E2S 0.00633454
IFNGR1 interferon gamma receptor 1 0.00633344
CEMIP cell migration inducing protein, hyaluronan binding 0.00632116
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00630901
TFF1 trefoil factor 1 0.00630886
PADI2 peptidyl arginine deiminase, type II 0.00630331
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00630072
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0062894
CD177 CD177 molecule 0.00628756
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00627952
FN1 fibronectin 1 0.00627174
POU2AF1 POU class 2 associating factor 1 0.00626273
AQP3 aquaporin 3 (Gill blood group) 0.0062435
ABHD4 abhydrolase domain containing 4 0.00622418
CALD1 caldesmon 1 0.00621085
REG1A regenerating islet-derived 1 alpha 0.00619705
ISG20 interferon stimulated exonuclease gene 20kDa 0.00618661
C1QBP complement component 1, q subcomponent binding protein 0.00618304
BIK BCL2-interacting killer (apoptosis-inducing) 0.00617598
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 0.0061651
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00616428
TICAM1 toll-like receptor adaptor molecule 1 0.00615097
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0061322
HIST1H2AC histone cluster 1, H2ac 0.00612841
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.00611442
RNF167 ring finger protein 167 0.00610995
ANXA2 annexin A2 0.00610028
CXCL2 chemokine (C-X-C motif) ligand 2 0.00608824
TPM4 tropomyosin 4 0.0060729
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00607185
COL15A1 collagen, type XV, alpha 1 0.00606457
TGFA transforming growth factor, alpha 0.00603887
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00603227
TUBB3 tubulin, beta 3 class III 0.00602942
ITM2C integral membrane protein 2C 0.0060268
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00601604
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00601065
CLMN calmin (calponin-like, transmembrane) 0.00600764
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00600289
CNTN1 contactin 1 0.00600026
IGFBP5 insulin-like growth factor binding protein 5 0.00599983
RTCA RNA 3'-terminal phosphate cyclase 0.00598115
GSR glutathione reductase 0.0059796
CD9 CD9 molecule 0.00597526
ACKR3 atypical chemokine receptor 3 0.00596709
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00595605
CXCL3 chemokine (C-X-C motif) ligand 3 0.00595021
SAV1 salvador family WW domain containing protein 1 0.00594118
NIP7 NIP7, nucleolar pre-rRNA processing protein 0.00592829
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00591803
L1CAM L1 cell adhesion molecule 0.00591748
EHBP1 EH domain binding protein 1 0.00591427
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00590365
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.00589856
C3ORF52 chromosome 3 open reading frame 52 0.00589469
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00589118
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.00588859
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00588141
CFAP20 cilia and flagella associated protein 20 0.00587322
RSL1D1 ribosomal L1 domain containing 1 0.00586387
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.00584205
NFIL3 nuclear factor, interleukin 3 regulated 0.00583974
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.00583853
NEU1 sialidase 1 (lysosomal sialidase) 0.0058373
MUC1 mucin 1, cell surface associated 0.00583268
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.00582787
PDZK1IP1 PDZK1 interacting protein 1 0.00582482
TNC tenascin C 0.00582411
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.00582071
PEG3 paternally expressed 3 0.00579894
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.00579755
LGALS2 lectin, galactoside-binding, soluble, 2 0.00579635
TSC22D3 TSC22 domain family, member 3 0.00578537
IER5 immediate early response 5 0.00577636
CD79A CD79a molecule, immunoglobulin-associated alpha 0.0057641

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0257043
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0193963
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0168892
KDM5D lysine (K)-specific demethylase 5D -0.0163431
SIRT3 sirtuin 3 -0.0146312
DAPK1 death-associated protein kinase 1 -0.0125079
ELN elastin -0.0123738
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0103292
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.0102097
SCGB1D2 secretoglobin, family 1D, member 2 -0.0101929
TLCD3A TLC domain containing 3A -0.00999711
BST2 bone marrow stromal cell antigen 2 -0.0099288
PDGFC platelet derived growth factor C -0.00987452
MET MET proto-oncogene, receptor tyrosine kinase -0.00976516
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -0.00968637
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00967563
IL7R interleukin 7 receptor -0.00965077
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -0.00925293
ACOT9 acyl-CoA thioesterase 9 -0.0091771
FBLN1 fibulin 1 -0.00917152
BGN biglycan -0.00916361
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00916156
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00911918
PBX1 pre-B-cell leukemia homeobox 1 -0.00905062
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.00902969
LRRC17 leucine rich repeat containing 17 -0.00901319
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00890071
ALOX5 arachidonate 5-lipoxygenase -0.00885213
ANXA3 annexin A3 -0.00881426
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00854918
C7 complement component 7 -0.00853101
COMP cartilage oligomeric matrix protein -0.0084857
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.00838567
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00832313
TIMP1 TIMP metallopeptidase inhibitor 1 -0.00813775
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00812112
ADGRF5 adhesion G protein-coupled receptor F5 -0.00810993
ICMT isoprenylcysteine carboxyl methyltransferase -0.0080881
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 -0.00808145
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00799983
IFITM1 interferon induced transmembrane protein 1 -0.00797849
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00794534
FBP1 fructose-1,6-bisphosphatase 1 -0.00794503
MFAP2 microfibrillar-associated protein 2 -0.00794375
ANXA10 annexin A10 -0.0078871
RXRA retinoid X receptor, alpha -0.00773062
DACH1 dachshund family transcription factor 1 -0.00771466
TBL1X transducin (beta)-like 1X-linked -0.0077012
CCDC92 coiled-coil domain containing 92 -0.00767817
PPARG peroxisome proliferator-activated receptor gamma -0.00767461
CDC7 cell division cycle 7 -0.00761433
FGFR3 fibroblast growth factor receptor 3 -0.00756956
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00755732
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00755677
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00755491
TNS3 tensin 3 -0.00754955
XYLT1 xylosyltransferase I -0.00753181
GSTM3 glutathione S-transferase mu 3 (brain) -0.00752084
ANO1 anoctamin 1, calcium activated chloride channel -0.00748861
PXDN peroxidasin -0.00747905
TPSAB1 tryptase alpha/beta 1 -0.00747046
C9 complement component 9 -0.00743412
USP9Y ubiquitin specific peptidase 9, Y-linked -0.00740518
ADIRF adipogenesis regulatory factor -0.00737711
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00735142
MMP2 matrix metallopeptidase 2 -0.00733843
NSD2 nuclear receptor binding SET domain protein 2 -0.00730115
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00723377
MN1 meningioma (disrupted in balanced translocation) 1 -0.00717738
FBN2 fibrillin 2 -0.00717428
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00716123
TNNI2 troponin I type 2 (skeletal, fast) -0.00712956
PRKCZ protein kinase C, zeta -0.00709267
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00701587
CDKN2A cyclin-dependent kinase inhibitor 2A -0.00699939
MOXD1 monooxygenase, DBH-like 1 -0.00696307
FZD10 frizzled class receptor 10 -0.00695013
C4BPA complement component 4 binding protein, alpha -0.00693601
NELL2 NEL-like 2 (chicken) -0.00692127
FANCL Fanconi anemia, complementation group L -0.0069027
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00689481
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00688551
OLFM4 olfactomedin 4 -0.00684668
SRPRA SRP receptor subunit alpha -0.00683489
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00682657
IRAK1 interleukin-1 receptor-associated kinase 1 -0.00680338
MECOM MDS1 and EVI1 complex locus -0.00678907
PDE10A phosphodiesterase 10A -0.00678465
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00673311
HYOU1 hypoxia up-regulated 1 -0.00671836
F5 coagulation factor V (proaccelerin, labile factor) -0.0067113
SMAD6 SMAD family member 6 -0.0067099
SUB1 SUB1 homolog (S. cerevisiae) -0.00668332
IGFBP1 insulin-like growth factor binding protein 1 -0.00668054
LTA4H leukotriene A4 hydrolase -0.00663798
LDOC1 leucine zipper, down-regulated in cancer 1 -0.00661402
SDC1 syndecan 1 -0.00655665
AMACR alpha-methylacyl-CoA racemase -0.00653145
SFTPD surfactant protein D -0.00651783
SLIT2 slit homolog 2 (Drosophila) -0.00651092
GATA2 GATA binding protein 2 -0.00648175
C2CD5 C2 calcium-dependent domain containing 5 -0.00643231
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.0064237
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00641569
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 -0.00632164
ESR1 estrogen receptor 1 -0.00631879
SUSD5 sushi domain containing 5 -0.00629802
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.0062672
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00626281
CTSZ cathepsin Z -0.00625242
ZBTB20 zinc finger and BTB domain containing 20 -0.00624935
ASPN asporin -0.00623191
ZNF589 zinc finger protein 589 -0.00623122
NXN nucleoredoxin -0.0062277
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00620668
FXYD1 FXYD domain containing ion transport regulator 1 -0.0061995
FAM193A family with sequence similarity 193, member A -0.00619299
ERBB2 erb-b2 receptor tyrosine kinase 2 -0.00618942
COL14A1 collagen, type XIV, alpha 1 -0.00616918
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.00616509
GUSB glucuronidase, beta -0.00615303
CA3 carbonic anhydrase III -0.00613706
USP48 ubiquitin specific peptidase 48 -0.00612066
NAV2 neuron navigator 2 -0.00610925
WWC3 WWC family member 3 -0.00609588
LDB2 LIM domain binding 2 -0.00609382
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.00608214
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00604063
IFITM2 interferon induced transmembrane protein 2 -0.00602784
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.00601634
CTSK cathepsin K -0.00600234
UBL4A ubiquitin-like 4A -0.00599842
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00599745
MYBPC1 myosin binding protein C, slow type -0.00599441
WFS1 Wolfram syndrome 1 (wolframin) -0.00599341
P3H2 prolyl 3-hydroxylase 2 -0.00598129
FERMT1 fermitin family member 1 -0.00598084
ZCCHC24 zinc finger, CCHC domain containing 24 -0.0059701
SUOX sulfite oxidase -0.00594042
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00593634
KRT18 keratin 18, type I -0.00593543
MTCL1 microtubule crosslinking factor 1 -0.00590768
ZNF423 zinc finger protein 423 -0.00590462
RIC8A RIC8 guanine nucleotide exchange factor A -0.00588905
CDK11A cyclin-dependent kinase 11A -0.00588806
RBM26 RNA binding motif protein 26 -0.00586449
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00585769
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -0.00585421
TALDO1 transaldolase 1 -0.00584702
PFAS phosphoribosylformylglycinamidine synthase -0.00583238
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -0.00583018
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.0058244
CBR4 carbonyl reductase 4 -0.00582369
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -0.00581501
DENND5A DENN/MADD domain containing 5A -0.00581361
TXNDC9 thioredoxin domain containing 9 -0.00581193
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -0.00578967
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -0.00578697
HOPX HOP homeobox -0.00576485
TSPAN8 tetraspanin 8 -0.00575161
TMCC1 transmembrane and coiled-coil domain family 1 -0.00572625
NDNF neuron-derived neurotrophic factor -0.00572078
KANK2 KN motif and ankyrin repeat domains 2 -0.00571284
DUSP4 dual specificity phosphatase 4 -0.00571048
CD93 CD93 molecule -0.00569115
HPN hepsin -0.00569106
STK10 serine/threonine kinase 10 -0.00567236
MPRIP myosin phosphatase Rho interacting protein -0.00566646
NAP1L4 nucleosome assembly protein 1-like 4 -0.00566128
ADGRL2 adhesion G protein-coupled receptor L2 -0.0056594
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.0056582
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -0.00564459
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase -0.00564156
ANGEL2 angel homolog 2 (Drosophila) -0.00563186
E2F3 E2F transcription factor 3 -0.00562969
LYZ lysozyme -0.00562686
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0056249
VCAM1 vascular cell adhesion molecule 1 -0.00562338
GSTP1 glutathione S-transferase pi 1 -0.00562183
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -0.00562169
CKM creatine kinase, muscle -0.00561261
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00558231
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.00556536
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -0.0055588
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -0.00554333
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 -0.00554252
BRD3 bromodomain containing 3 -0.00554063
TOMM34 translocase of outer mitochondrial membrane 34 -0.00553632
PHKA2 phosphorylase kinase, alpha 2 (liver) -0.00553331
GPR143 G protein-coupled receptor 143 -0.00552663
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.0055251
CPA3 carboxypeptidase A3 (mast cell) -0.00548085
CBS cystathionine-beta-synthase -0.00546769
KLHL41 kelch-like family member 41 -0.00546139
GRP gastrin-releasing peptide -0.00545278
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle -0.0054233
PYGM phosphorylase, glycogen, muscle -0.00541352
SIM2 single-minded family bHLH transcription factor 2 -0.00539628
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00539072
JADE1 jade family PHD finger 1 -0.00538886
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00538347
KIF20A kinesin family member 20A -0.00537229
LEPR leptin receptor -0.0053689
CBX3 chromobox homolog 3 -0.00536659
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00535823
FSTL1 follistatin-like 1 -0.00535506
CRHBP corticotropin releasing hormone binding protein -0.00535002
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00534547
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00533057
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.00532569
MANSC1 MANSC domain containing 1 -0.00532317
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00532306
MYBPC2 myosin binding protein C, fast type -0.00530893
LDHA lactate dehydrogenase A -0.00530638
F9 coagulation factor IX -0.00529935
SLC38A4 solute carrier family 38, member 4 -0.0052962
PASK PAS domain containing serine/threonine kinase -0.00529076
TM4SF4 transmembrane 4 L six family member 4 -0.00528938
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00527784
VDAC1 voltage-dependent anion channel 1 -0.00527619
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 -0.00527243
LIMCH1 LIM and calponin homology domains 1 -0.00527154
TENT4A terminal nucleotidyltransferase 4A -0.00527075
COQ8A coenzyme Q8A -0.00526246
KLK2 kallikrein-related peptidase 2 -0.00526195
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.00525406
ADAR adenosine deaminase, RNA-specific -0.00525243
TRIM5 tripartite motif containing 5 -0.00524927
MYOM1 myomesin 1 -0.00524853
APOF apolipoprotein F -0.00524654
LOXL1 lysyl oxidase-like 1 -0.00524182
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.0052257
NKTR natural killer cell triggering receptor -0.00522425
C1ORF216 chromosome 1 open reading frame 216 -0.00521577
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00521287
RESF1 retroelement silencing factor 1 -0.00520919
PON1 paraoxonase 1 -0.00520812
KIAA0232 KIAA0232 -0.00520408
EHD2 EH-domain containing 2 -0.00518812
ACADVL acyl-CoA dehydrogenase, very long chain -0.00516912
ECHDC3 enoyl CoA hydratase domain containing 3 -0.00516541
MEF2C myocyte enhancer factor 2C -0.00515807
WDFY3 WD repeat and FYVE domain containing 3 -0.00515317
COL5A2 collagen, type V, alpha 2 -0.00513626
TMSB15A thymosin beta 15a -0.00513462
DVL1 dishevelled segment polarity protein 1 -0.00513296
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00513027
GLS glutaminase -0.00512977
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -0.00512884