MRK-NU-1 Gene Set

Dataset COSMIC Cell Line Gene CNV Profiles
Category genomics
Type cell line
Description Human mammary gland carcinoma cell line, established from a 46 years old female. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003679)
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Genes

99 genes with high or low copy number in MRK-NU-1 relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

high copy number

Symbol Name Standardized Value
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 4.51153
RND3 Rho family GTPase 3 4.51153
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 4.51153
AHCTF1P1 AT hook containing transcription factor 1 pseudogene 1 4.51153
MIR4773-1 microRNA 4773-1 4.51153
MIR4773-2 microRNA 4773-2 4.51153
RBM43 RNA binding motif protein 43 3.12177
NMI N-myc (and STAT) interactor 3.12177
SRGAP2C SLIT-ROBO Rho GTPase activating protein 2C 2.93899
C4BPA complement component 4 binding protein, alpha 2.93899
C4BPB complement component 4 binding protein, beta 2.93899
EIF2D eukaryotic translation initiation factor 2D 2.93899
YOD1 YOD1 deubiquitinase 2.93899
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.93899
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2.93899
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.93899
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 2.93899
IL24 interleukin 24 2.93899
C1ORF116 chromosome 1 open reading frame 116 2.93899
CR2 complement component (3d/Epstein Barr virus) receptor 2 2.93899
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 2.93899
CD46 CD46 molecule, complement regulatory protein 2.93899
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 2.93899
MIR29C microRNA 29c 2.93899
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.93899
CHIT1 chitinase 1 (chitotriosidase) 2.93899
PIGR polymeric immunoglobulin receptor 2.93899
CTSE cathepsin E 2.93899
AVPR1B arginine vasopressin receptor 1B 2.93899
IL20 interleukin 20 2.93899
C1ORF186 chromosome 1 open reading frame 186 2.93899
BTG2 BTG family, member 2 2.93899
IL19 interleukin 19 2.93899
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.93899
IL10 interleukin 10 2.93899
CR1L complement component (3b/4b) receptor 1-like 2.93899
FCMR Fc fragment of IgM receptor 2.93899
FCAMR Fc receptor, IgA, IgM, high affinity 2.93899
REN renin 2.76305
SNORD95 small nucleolar RNA, C/D box 95 2.76305
PLEKHA6 pleckstrin homology domain containing, family A member 6 2.76305
PPP1R15B protein phosphatase 1, regulatory subunit 15B 2.76305
FMOD fibromodulin 2.76305
NFASC neurofascin 2.76305
ETNK2 ethanolamine kinase 2 2.76305
KISS1 KiSS-1 metastasis-suppressor 2.76305
LRRN2 leucine rich repeat neuronal 2 2.76305
LINC00628 long intergenic non-protein coding RNA 628 2.76305
GOLT1A golgi transport 1A 2.76305
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 2.76305
MDM4 MDM4, p53 regulator 2.76305
OPTC opticin 2.64759
SNRPE small nuclear ribonucleoprotein polypeptide E 2.64759
ZBED6 zinc finger, BED-type containing 6 2.64759
LINC00260 long intergenic non-protein coding RNA 260 2.64759
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 2.64759
LINC00303 long intergenic non-protein coding RNA 303 2.64759
ZC3H11A zinc finger CCCH-type containing 11A 2.64759
LAX1 lymphocyte transmembrane adaptor 1 2.64759
SNORA77 small nucleolar RNA, H/ACA box 77 2.64759
PRELP proline/arginine-rich end leucine-rich repeat protein 2.64759
SOX13 SRY (sex determining region Y)-box 13 2.64759
ITGB6 integrin, beta 6 2.14311
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.14311
LY75 lymphocyte antigen 75 2.14311
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 2.14311
CD302 CD302 molecule 2.14311
LY75-CD302 LY75-CD302 readthrough 2.14311
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 2.14116
CCDC148 coiled-coil domain containing 148 2.14116
UPP2 uridine phosphorylase 2 2.14116
CCDC148-AS1 CCDC148 antisense RNA 1 2.14116
CYTIP cytohesin 1 interacting protein 2.14116
PKP4 plakophilin 4 2.14116
ACVR1C activin A receptor, type IC 2.14116
RBMS1 RNA binding motif, single stranded interacting protein 1 2.12931
ACVR1 activin A receptor, type I 2.12703
MIR4785 microRNA 4785 2.12703

low copy number

Symbol Name Standardized Value
CD164 CD164 molecule, sialomucin -5.12655
DEPDC5 DEP domain containing 5 -3.7119
GPR19 G protein-coupled receptor 19 -3.38669
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.36169
APOLD1 apolipoprotein L domain containing 1 -3.36169
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -3.36169
FOXK2 forkhead box K2 -3.2703
LOC100996634 transmembrane protein FLJ37396 -3.24687
ARMC2 armadillo repeat containing 2 -3.24687
CEP57L1 centrosomal protein 57kDa-like 1 -3.24687
CCDC162P coiled-coil domain containing 162, pseudogene -3.24687
SEC63 SEC63 homolog (S. cerevisiae) -3.24687
OSTM1 osteopetrosis associated transmembrane protein 1 -3.24687
SCML4 sex comb on midleg-like 4 (Drosophila) -3.24687
LINC00222 long intergenic non-protein coding RNA 222 -3.24687
NR2E1 nuclear receptor subfamily 2, group E, member 1 -3.24687
SESN1 sestrin 1 -3.24687
CREBL2 cAMP responsive element binding protein-like 2 -3.16503
FOXO3 forkhead box O3 -3.11641
LACE1 lactation elevated 1 -3.11641
SNX3 sorting nexin 3 -3.05196